JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.104187
Mohammad Abed MD , Shi-Joon Yoo MD, PhD , Lee N. Benson MD
{"title":"Recanalization of Atretic Aortic Arch in Teenager Guided by Cardiac Magnetic-Resonance","authors":"Mohammad Abed MD , Shi-Joon Yoo MD, PhD , Lee N. Benson MD","doi":"10.1016/j.jaccas.2025.104187","DOIUrl":"10.1016/j.jaccas.2025.104187","url":null,"abstract":"<div><h3>Background</h3><div>Systemic hypertension secondary to total occlusion of the aortic arch is a rare etiology in children.</div></div><div><h3>Case Summary</h3><div>This case report describes the successful management of a 12-year-old girl with an atretic aortic arch by percutaneous recanalization guided by cardiac magnetic resonance (CMR) and angiography. The orientation of the atretic segment seen by CMR suggested a percutaneous intervention would be feasible. A coronary guidewire was used to traverse the atretic arch, and a balloon-expandable covered stent was deployed to restore luminal continuity.</div></div><div><h3>Discussion</h3><div>Atretic aortic arch recanalization is a high-risk surgical procedure owing to extensive collateral circulation. CMR plays a key role in preprocedural planning, detailing the vascular anatomy as well as collateral circulation.</div></div><div><h3>Take-Home Message</h3><div>This review illustrates the important role of CMR in planning percutaneous interventions as a feasible alternative to high-risk surgical repair in complex anatomies.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104187"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.104200
Mohammed Abutaqa MD , Hamza A. Abdul-Hafez MD , Hasan Alkhatib MD , Helmi Mahmoud Tamimi MD , Bilal Adwan MD
{"title":"Using 3D Heart Printing for Planning to Repair a Complex Congenital Heart Disease via Minimal Invasive Thoracotomy","authors":"Mohammed Abutaqa MD , Hamza A. Abdul-Hafez MD , Hasan Alkhatib MD , Helmi Mahmoud Tamimi MD , Bilal Adwan MD","doi":"10.1016/j.jaccas.2025.104200","DOIUrl":"10.1016/j.jaccas.2025.104200","url":null,"abstract":"<div><h3>Background</h3><div>Cor triatriatum sinister is a rare congenital heart disease that can mimic left atrial obstructive lesions. Symptoms vary based on the severity of obstruction.</div></div><div><h3>Case Summary</h3><div>We report a case of a 14-year-old girl with severe exercise intolerance. Echocardiography and computed tomography scan revealed a fibromuscular membrane causing left atrial obstruction and an anomalous venous drainage with a persistent left superior vena cava to the coronary sinus. Surgical intervention is definitive, typically via sternotomy.</div></div><div><h3>Discussion</h3><div>Given the complexity and lack of expertise in minimal invasive thoracotomy for such lesions, we used 3-dimensional (3D) heart printing for virtual surgical planning. This approach facilitated a safe and precise repair. To our knowledge, this is the first reported case using 3D printing to enable a minimally invasive thoracotomy for cor triatriatum sinister correction.</div></div><div><h3>Take-Home Messages</h3><div>Minimally invasive approaches should not be dismissed for complex congenital heart defects. Multimodal imaging can enhance surgical feasibility.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104200"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.104014
Joseph Burns MD , Lindsay F. Eilers MD , Stephen J. Dolgner MD , Edward J. Hickey MD , Silvana Molossi MD, PhD
{"title":"Multimodal Imaging Directs Decision Making in Intraseptal L-AAOCA","authors":"Joseph Burns MD , Lindsay F. Eilers MD , Stephen J. Dolgner MD , Edward J. Hickey MD , Silvana Molossi MD, PhD","doi":"10.1016/j.jaccas.2025.104014","DOIUrl":"10.1016/j.jaccas.2025.104014","url":null,"abstract":"<div><h3>Background</h3><div>Congenital coronary artery abnormalities represent an uncommon class of congenital heart disease with an associated risk of sudden cardiac death. There is a paucity of data for the evaluation and management of affected patients with an intraseptal course.</div></div><div><h3>Case Summary</h3><div>A 27-year-old woman was found to have a single coronary trunk arising from the right sinus with a 2.7 cm intraseptal course of the left main coronary artery. She underwent stress cardiac magnetic resonance and catheterization, to assess for inducible ischemia before surgical repair with transconal unroofing. Her recovery was uneventful, and she remains free of symptoms.</div></div><div><h3>Discussion</h3><div>Management of congenital coronary artery anomalies requires an exhaustive evaluation. Further studies are warranted to define the ideal work-up, indication, and timing of intervention and the efficacy of medical management in improving symptoms.</div></div><div><h3>Take-Home Messages</h3><div>Congenital coronary anomalies represent a rare but consequential cause of exertional chest pain. This diagnosis requires multimodal imaging to inform decision making.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104014"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.104197
Abdellaziz Dahou MD, PhD, Nathanael Tran MD, Jacob Dal-Bianco MD, Danita Sanborn MD, MMSC, Judy Hung MD, Sarah Tsiaras MD
{"title":"Usefulness of Echocardiography Contrast Agents for the Detection of Residual Leak After Percutaneous LAA Closure Device Implantation","authors":"Abdellaziz Dahou MD, PhD, Nathanael Tran MD, Jacob Dal-Bianco MD, Danita Sanborn MD, MMSC, Judy Hung MD, Sarah Tsiaras MD","doi":"10.1016/j.jaccas.2025.104197","DOIUrl":"10.1016/j.jaccas.2025.104197","url":null,"abstract":"<div><h3>Background</h3><div>Residual leaks after percutaneous left atrial appendage closure (LAAC) are associated with an increase in thromboembolic events. Therefore, their detection and correction are crucial.</div></div><div><h3>Case Summary</h3><div>This case was a 78-year-old woman with history of long-standing atrial fibrillation complicated by transient ischemic attack who underwent a percutaneous LAAC with a WATCHMAN device, with no residual leak. Initial follow-up transesophageal echocardiography (TEE) was unremarkable and anticoagulation therapy was stopped. Subsequent TEE was performed due to abnormal gap around the device noted on cardiac computed tomography. TEE findings were concerning for residual leak by color Doppler, but a definite diagnosis could not be made. An echo contrast agent was then used, which helped establish a definite diagnosis of residual leak and helped guide further management.</div></div><div><h3>Discussion</h3><div>This is the first case to show the usefulness of echo contrast agents to detect residual leaks after LAAC.</div></div><div><h3>Take-Home Message</h3><div>The use of contrast agents during TEE represents a low-cost and readily available tool that may become an alternative to cardiac computed tomography for the detection of residual leaks after LAAC in challenging cases, when color Doppler is inconclusive.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104197"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atrial Septal Defect With Right-to-Left Shunt Without Pulmonary Hypertension","authors":"Ryusuke Sekii MD , Shingo Kato MD, PhD , Naoki Nakayama MD, PhD , Kazuki Fukui MD, PhD , Masanori Ito RT , Tae Iwasawa MD, PhD , Masaaki Konishi MD, PhD , Daisuke Utsunomiya MD, PhD , Kiyoshi Hibi MD, PhD","doi":"10.1016/j.jaccas.2025.103853","DOIUrl":"10.1016/j.jaccas.2025.103853","url":null,"abstract":"<div><h3>Background</h3><div>Four-dimensional flow magnetic resonance imaging (MRI) enhances the evaluation of complex cardiovascular diseases. We used MRI and advanced imaging modalities to assess a right-to-left shunt through an atrial septal defect without pulmonary hypertension (PH).</div></div><div><h3>Case Summary</h3><div>An 84-year-old woman with persistent hypoxemia was found to have a significant right-to-left shunt without PH. Computed tomography angiography revealed severe aortic tortuosity compressing the right atrium, likely contributing to continuous shunting. Four-dimensional flow MRI visualized the shunt and quantified a Q<sub>p</sub>/Q<sub>s</sub> ratio of 0.61, consistent with invasive measurements.</div></div><div><h3>Discussion</h3><div>Unlike classic platypnea-orthodeoxia syndrome, extreme aortic tortuosity may cause persistent right-to-left shunting even in the supine position. This case highlights how age-related anatomical changes contribute to intracardiac shunting and underscores the utility of advanced imaging.</div></div><div><h3>Take-Home Message</h3><div>Right-to-left shunting without PH can persist because of anatomical factors. In this case, a correct diagnosis was obtained through comprehensive imaging, including 4-dimensional flow MRI.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 103853"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fulminant Myocarditis With Normal Inflammatory Markers","authors":"Deva Nirthanakumaran MD, BMS , Shahab Pathan MBBS , Devang Parikh MBBS , Faraz Pathan MBBS, PhD","doi":"10.1016/j.jaccas.2025.103878","DOIUrl":"10.1016/j.jaccas.2025.103878","url":null,"abstract":"<div><h3>Background</h3><div>Fulminant myocarditis is a rare, rapidly progressive and life-threatening condition requiring early diagnosis and management.</div></div><div><h3>Case Summary</h3><div>We present the case of a 31-year-old man who presented with sudden onset chest pain; though his initial echocardiography was largely unremarkable, and angiography ruled out acute coronary syndrome, the patient developed worsening pain with rising high-sensitivity troponin markers. Cardiac magnetic resonance imaging revealed widespread transmural late gadolinium enhancement throughout the left ventricle, which prompted urgent transfer to a quaternary center before the patient’s acute deterioration. The patient deteriorated from symptom onset to overt cardiogenic shock requiring intubation, mechanical circulatory support, and high-dose immunosuppression within 25 hours.</div></div><div><h3>Discussion</h3><div>This case underscores the importance of multimodality imaging for rapid decision-making in diagnosing myocarditis, particularly when clinical suspicion is high despite initial nonspecific biochemical tests and echocardiography.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 103878"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.104163
Kevin Lee MD , Kifah Hussain MD , Christopher Ding MD , Daniel Tarchala MBA , Jonathan Rosenberg MD , Amit Pursnani MD
{"title":"Utility of Multimodality Imaging in Superior Anomalous Pulmonary Venous Return With Inferior Sinus Venosus Defect","authors":"Kevin Lee MD , Kifah Hussain MD , Christopher Ding MD , Daniel Tarchala MBA , Jonathan Rosenberg MD , Amit Pursnani MD","doi":"10.1016/j.jaccas.2025.104163","DOIUrl":"10.1016/j.jaccas.2025.104163","url":null,"abstract":"<div><h3>Background</h3><div>Inferior sinus venosus defects (SVD) are rare congenital malformations involving an overriding inferior vena cava resulting in an interatrial connection.</div></div><div><h3>Case Summary</h3><div>A female patient with multiple cryptogenic strokes was found to have a positive agitated saline study without evidence of atrial septal defect on transesophageal echocardiography. Cardiac computed tomography was used to diagnose partial anomalous pulmonary venous return (PAPVR) of the right superior and middle pulmonary veins associated with an inferior SVD. Three-dimensional printing was then used to aid in surgical planning.</div></div><div><h3>Discussion</h3><div>Traditionally, an inferior SVD is associated with inferior PAPVR. This is a rare case of an inferior SVD with superior PAPVR that highlights the importance of multimodality imaging for accurate diagnosis and management.</div></div><div><h3>Take-Home Messages</h3><div>Multimodality imaging is important in evaluating congenital heart disease, especially axial imaging such as cardiac computed tomography or cardiac magnetic resonance. Three-dimensional printed models can assist in presurgical planning to fully understand complex cardiac anatomy.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104163"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JACC. Case reportsPub Date : 2025-06-25DOI: 10.1016/j.jaccas.2025.103772
Julio Echarte-Morales MD , Berenice Caneiro-Queija MD, PhD , Manuel Barreiro-Pérez MD, PhD , Francisco Estévez-Cid MD , Rocío González-Ferreiro MD, PhD , Miguel Piñón-Esteban MD , José Antonio Baz-Alonso MD , Rodrigo Estévez-Loureiro MD, PhD , Andrés Iñiguez-Romo MD, PhD
{"title":"Concomitant Transcatheter Aortic and Mitral Valve Replacement","authors":"Julio Echarte-Morales MD , Berenice Caneiro-Queija MD, PhD , Manuel Barreiro-Pérez MD, PhD , Francisco Estévez-Cid MD , Rocío González-Ferreiro MD, PhD , Miguel Piñón-Esteban MD , José Antonio Baz-Alonso MD , Rodrigo Estévez-Loureiro MD, PhD , Andrés Iñiguez-Romo MD, PhD","doi":"10.1016/j.jaccas.2025.103772","DOIUrl":"10.1016/j.jaccas.2025.103772","url":null,"abstract":"<div><h3>Background</h3><div>Multivalvular heart disease is a highly prevalent condition that causes significant morbidity and mortality.</div></div><div><h3>Case Summary</h3><div>A 75-year-old man presented with worsening functional class and asthenia. A transthoracic echocardiogram showed severe aortic stenosis and severe mitral stenosis. The patient underwent transcatheter aortic and mitral valve replacement in the same procedure.</div></div><div><h3>Discussion</h3><div>There is a lack of solid evidence regarding the management of multivalvular disease. Severe mitral stenosis can influence aortic stenosis, potentially leading to a low-flow, low-gradient profile. Establishing a streamlined workflow between transesophageal echo and cardiac tomography optimizes procedural safety, efficiency, and outcomes in patients with concomitant mitral and aortic disease.</div></div><div><h3>Take-Home Messages</h3><div>This case highlights the relevance of multimodality imaging for procedural planning in complex multivalvular disease. Concomitant transcatheter implantation of transcatheter aortic valve replacement for aortic stenosis followed by a transcatheter mitral valve replacement in mitral stenosis is a feasible option for patients at high surgical risk.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 103772"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Mitral Regurgitation Unveiling Infective Endocarditis in an Adolescent With Mitral Valve Prolapse","authors":"Adelaide Iervolino MD , Monica Barki MD , Giacomo Ingallina MD , Francesco Ancona MD , Elena Busnardo MD , Arturo Chiti MD , Vincenzo Rizza MD , Ludovica Bognoni MD , Eustachio Agricola MD","doi":"10.1016/j.jaccas.2025.104015","DOIUrl":"10.1016/j.jaccas.2025.104015","url":null,"abstract":"<div><h3>Background</h3><div>Infective endocarditis (IE) is a potentially life-threatening condition, possibly occurring in overlap with preexisting structural cardiac abnormalities. The Duke Criteria represent a cornerstone in the diagnosis of IE, and the detection of new regurgitation represents a major criterion that may be overlooked.</div></div><div><h3>Case Summary</h3><div>We present a case of a 14-year-old girl with mitral valve prolapse (MVP) who developed IE. Despite initial negative echocardiographic findings for vegetations, thorough analysis revealed the presence of a new regurgitation jet at P3 scallop, thereby distinguishing it from the mild preexisting central mitral regurgitation.</div></div><div><h3>Discussion</h3><div>This case highlights the diagnostic challenges of IE when vegetations are absent on echocardiography. In this setting, recognizing a new jet from a preexisting regurgitation is crucial in making the diagnosis.</div></div><div><h3>Take-Home Messages</h3><div>Echocardiography represents the cornerstone for diagnosing IE. Indeed, in patients with MVP, careful assessment of new regurgitation, even in the absence of visible vegetations, should raise suspicion for IE.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 16","pages":"Article 104015"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}