Journal of adolescent and young adult oncology最新文献

{"title":"Recapturing Life: Virtual Peer-Based Psychological Support for Adolescent and Young Adult Cancer Survivors Delivered in the Community.","authors":"Elin Irestorm, Claire E Wakefield, Kate Hetherington, Brittany C McGill, Holly E Evans, Fiona McDonald, Pandora Patterson, Annette Beattie, Richard J Cohn, Ursula M Sansom-Daly","doi":"10.1177/21565333251369689","DOIUrl":"10.1177/21565333251369689","url":null,"abstract":"<p><strong>Purpose: </strong>Adolescent and young adult (AYA) cancer survivors have unique psychological needs and require tailored support, as they transition from hospital settings following cancer treatment. This study aimed to evaluate the safety and clinical effectiveness of the online \"Recapture Life\" program to improve AYA aged survivors' psychological adjustment in early cancer survivorship.</p><p><strong>Methods: </strong>The intervention was delivered in community settings, by trained psychosocial staff at partnering cancer-support organizations. The participants received seven cognitive behavioral therapy-based online sessions six weekly 90-minute group sessions and a booster session. A pre-post design was used, where participants completed patient-reported outcome measures at intake, and 6 months after intervention completion. Measures assessed psychological distress, cancer-related problems, peer support, and program benefit/burden.</p><p><strong>Results: </strong>Thirty 13-39-year-olds with mixed cancer diagnoses (mean time since diagnosis 2.9 years) completed both assessments. We did not find evidence that the intervention reduced psychological distress. However, 6 months after completing Recapture Life, AYAs reported fewer cancer-related problems (<i>t</i>(29) = 2.63, <i>p</i> = 0.003) and improved peer support (<i>t</i>(29) = 8.04, <i>p</i> = 0.015), with medium effect sizes. Most participants reported no program burden (72%) and found Recapture Life at least somewhat beneficial (79%). Most (73%) reported staying in contact with AYAs from their group post-intervention.</p><p><strong>Conclusion: </strong>Six months after completing Recapture Life, AYAs reported having more peer support and fewer cancer-related problems. This study addresses a well-documented gap in psychological services tailored to AYA survivors' needs. Recapture Life delivered in the community addressed areas of concern for the AYAs and may teach adaptive skills for survivors adjusting to life after cancer treatment.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"187-195"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transition of Childhood Cancer Survivors into Adult Health Care: A Perspective from Adult Care.","authors":"Tomoko Katsui Taniyama, Akiko Higuchi, Midori Kadowaki, Shinji Mochizuki, Hideko Uryu, Takeshi Inagaki, Hajime Oishi, Miyuki Sadatsuki, Akiyo Tanabe, Makiko Hashimoto, Shuji Kubota, Daisuke Katagiri, Chikako Kiyotani, Kimikazu Matsumoto, Chikako Shimizu","doi":"10.1177/21565333251372457","DOIUrl":"10.1177/21565333251372457","url":null,"abstract":"<p><strong>Purpose: </strong>The number of long-term childhood cancer survivors (CCSs) has been increasing, and the importance of transitioning from pediatric to adult care has been advocated. This study aimed to describe the health problems of adult CCSs from adult-care perspectives.</p><p><strong>Methods: </strong>We conducted a chart review of adult CCSs aged ≥18 years who visited a transition clinic in adult care between June 2019 and March 2024.</p><p><strong>Results: </strong>The study included 25 CCSs, with a median follow-up period of 14 months. The median number of medical departments requiring regular clinic visits was three (range 1-7). Among the participants, 15 (60%) had at least one severe health problem (grade 3 or higher). Notably, 45% (5 of 11) of participants with cardiovascular disease and 64% (9 of 14) of those with bone mineral density (BMD) deficiency were diagnosed after transition. During the follow-up period, 13 CCSs were hospitalized in the adult ward. Additionally, 52% (13 of 25) of the CCSs requested psychosocial intervention. Five CCSs who had health problems such as pituitary insufficiency, hearing loss, and visual impairment needed ongoing support from social workers.</p><p><strong>Conclusion: </strong>Adult CCSs present with multiple health problems and risks. Because the health care system is different between adult care and pediatric care, comprehensive re-evaluation of health problems and care optimization from the adult-care perspective is important for the successful transition of CCSs to adult care.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"196-204"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Characteristics of Psychiatric Disorders in Adolescent and Young Adult Patients with Malignant Brain Tumors.","authors":"Eun Sang Yi, Yunseop Kim, Chaeeun Cho, Jimin Kim, O Kyu Noh, Jun Eun Park","doi":"10.1177/21565333251386716","DOIUrl":"10.1177/21565333251386716","url":null,"abstract":"<p><strong>Purpose: </strong>Adolescents and young adults (AYAs) with brain tumors are at an increased risk of developing psychiatric disorders. We aimed to investigate the incidence and characteristics of psychiatric disorders in AYA patients with brain tumors.</p><p><strong>Methods: </strong>Using the Korean Classification of Diseases, we identified a cohort of AYA patients (aged 15-34 years) diagnosed with malignant brain neoplasms (C71) between 2003 and 2016 from the Korean National Health Insurance Claims Database. The analysis included 7052 patients.</p><p><strong>Results: </strong>The 10-year cumulative incidence rate of psychiatric disorders was 21.5%. The most common psychiatric disorders were neurotic, stress-related, and somatoform disorders (11.4%), followed by mood (affective) disorders (9.4%). Factors associated with a higher incidence of psychiatric disorders included female sex (hazard ratio [HR] 1.16, 95% confidence interval [CI]: 1.05-1.28, <i>p</i> = 0.005), history of seizures (HR: 1.47, 95% CI: 1.31-1.66, <i>p</i> < 0.001), and brain tumor diagnosis during the latter part of the study period (HR: 1.14, 95% CI: 1.03-1.27, <i>p</i> = 0.010). Psychiatric hospital admissions were most frequent among patients with schizophrenia, schizotypal disorders, and delusional disorders (<i>n</i> = 5). The most common psychiatric disorders requiring psychotherapy were neurotic, stress-related, and somatoform (<i>n</i> = 580) and mood (<i>n</i> = 526) disorders.</p><p><strong>Conclusion: </strong>A significant number of AYA patients with brain tumors develop psychiatric disorders after diagnosis, and most require treatment. Early detection through screening programs and personalized psychological support during and after cancer treatment may improve the mental health and quality of life of AYA patients with brain tumors.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"179-186"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Adolescent and Young Adult Patients Undergoing Pancreatectomy for Malignant Tumors: A 20-Year Single Institution Experience.","authors":"Naonori Kawakubo, Minoru Esaki, Satoshi Nara, Akinori Miyata, Takahiro Mizui, Ryosuke Umino, Junkichi Takemoto, Tomoro Hishiki, Akihiro Yoneda","doi":"10.1177/21565333251394590","DOIUrl":"10.1177/21565333251394590","url":null,"abstract":"<p><strong>Background and aim: </strong>Adolescent and young adult (AYA) patients who require pancreatectomy are rare. There are few reports concerning the characteristics of AYA patients undergoing pancreatectomy for malignant tumors. This study aimed to clarify the characteristics and outcomes of AYA patients who had undergone pancreatectomy.</p><p><strong>Methods: </strong>AYA patients (age 15-35 years) who underwent pancreatectomy at our institution between 1995 and 2018 were included in this study. The diagnosis, operative procedure, complications, mortality, and survival were retrospectively analyzed.</p><p><strong>Results: </strong>Forty-seven patients underwent pancreatectomy (median age 29 years; range, 16-35 years). The diagnoses were solid-pseudopapillary neoplasm (SPN; <i>n</i> = 21 [44.6%]), neuroendocrine neoplasm (NEN; <i>n</i> = 12 [25.5%]), adenocarcinoma (<i>n</i> = 5 [10.6%]), and others (<i>n</i> = 9 [19.1%]). The surgical procedures included pancreatoduodenectomy (PD; <i>n</i> = 17 [36.1%]), distal pancreatectomy (DP; <i>n</i> = 18 [38.2%]), middle pancreatectomy (<i>n</i> = 8 [17.0%]), and tumor enucleation (<i>n</i> = 4 [8.5%]). The most common postoperative complication was pancreatic fistula (POPF) (<i>n</i> = 29 [61.7%]). Hemorrhage was noted in one case, but the surgical mortality rate was 0%. Long-term complications included four cases of pancreatitis, three cases of diabetes, two cases of bowel obstruction, and one case of cholangitis. The 5-year recurrence-free-survival (RFS) and overall-survival (OS) rates in patients with SPN/NEN/others were 91.8% and 97.5%, respectively. In contrast, the 5-year RFS and OS rates in patients with adenocarcinoma were 53.3% and 80.0%, respectively.</p><p><strong>Conclusion: </strong>Most AYA patients who underwent pancreatectomy had low-grade malignancies and showed a favorable survival. Although POPF and pancreatitis frequently occur, radical surgery-even major pancreatectomy such as PD and DP-is feasible and effective in AYA patients with malignant tumors.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"220-225"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a Tool to Assess Needs of AYA Cancer Survivors in Rural, Medically Underserved Regions of Southwestern Indiana.","authors":"Brittany J Ritzman, Joseph Sakel, Ryan Heumann, Oseme Okoruwa, Bridget Hawryluk, Courtney Moore, Lisa Parks, Brandon Cockrum, Dustin Lynch, Andrea Kiser, Sarah Wiehe, Kara Garcia, Tammy Sajdyk","doi":"10.1177/21565333251405138","DOIUrl":"10.1177/21565333251405138","url":null,"abstract":"<p><p>While cancer has sustained impacts on survivors, no unified strategy exists to assess the ongoing needs of survivors. Adolescent and young adult (AYA) cancer survivors have unique needs and concerns related to their life stages, including education, career, relationships, and family planning, all of which may be impacted by cancer and its treatments. In this study, we co-designed with survivors a distributable digital tool for assessing needs among this population. Because of known disparities in outcomes for survivors in rural or medically underserved areas, initial tool development focused on feedback from AYA survivors in one such region (Southwest Indiana).</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"226-231"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145833981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Marriage and Parenthood in Adult Survivors of Childhood Cancers: An Indian Perspective.","authors":"Maya Prasad, Venkata Ramamohan Gollamudi, Savita Goswami","doi":"10.1177/21565333261456938","DOIUrl":"https://doi.org/10.1177/21565333261456938","url":null,"abstract":"<p><strong>Background: </strong>We analyzed the predictors of marriage and parenthood in our cohort of adult survivors of childhood cancer.</p><p><strong>Methods: </strong>We conducted a retrospective cohort analysis of adult survivors of childhood cancer aged > 25 years at a tertiary cancer center in India, evaluating marital status, parenthood, and associated predictors using multivariable logistic regression.</p><p><strong>Results: </strong>Among 844 survivors, 36.4% of males and 37.6% of females were ever married. On multivariable analysis, male sex (odds ratio [OR] 0.58, 95% confidence interval [CI] 0.41-0.83, <i>p</i> = 0.003) and diagnosis of central nervous system (CNS) tumor/retinoblastoma (OR 0.42, 95% CI 0.22-0.81, <i>p</i> = 0.009) were associated with lower likelihood of marriage, while employment was strongly associated with higher likelihood (OR 3.75, 95% CI 2.62-5.37, <i>p</i> < 0.001).Among married survivors, treatment before 2000 was associated with a higher likelihood of parenthood (OR 3.94, 95% CI 2.20-7.06, <i>p</i> < 0.001), while other treatment-related factors were not significantly associated. Highly gonadotoxic treatment (OR 2.19, 95% CI 1.22-3.93, <i>p</i> = 0.01) was associated with use of assisted reproductive technology.</p><p><strong>Conclusions: </strong>Sociodemographic and temporal factors, particularly employment and treatment era, were the primary determinants of marriage and parenthood in this cohort.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261456938"},"PeriodicalIF":1.2,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148054607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preference of Adolescent and Young Adult Patients with Hematological Malignancy Regarding the Disclosure of Bad News.","authors":"Yuko Osugi, Maiko Fujimori, Miwa Ozawa, Jiro Takeuchi, Masami Inoue, Junichi Kitagawa, Yuma Tada, Keishiro Amano, Yuhki Koga, Yosuke Uchitomi, Kazuhiro Ikegame","doi":"10.1177/21565333261450843","DOIUrl":"https://doi.org/10.1177/21565333261450843","url":null,"abstract":"<p><strong>Purpose: </strong>To clarify communication preferences regarding the disclosure of bad news in adolescent and young adult (AYA) patients with hematological malignancies.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from January 2021 to March 2022 using a five-point Likert-scale questionnaire. Participants were patients diagnosed between the ages of 15-29 years and aged <40 years at the time of the survey. Preferences regarding physician communication during the disclosure of bad news were assessed. Trend tests were performed for items showing substantial interindividual variability.</p><p><strong>Results: </strong>Data from 90 participants (49 male) were analyzed. Compared with adult cancer populations, AYA patients were less likely to prefer receiving bad news in the presence of family or to prioritize reassurance or emotional support. Over 90% preferred detailed and concrete information about their medical condition, including unfavorable information, and wanted physicians to listen to their distress and concerns. Seventy percent preferred receiving information about life expectancy. Participants wanted physicians to break bad news to them first while also valuing physicians' consideration for their family members. Trend test results indicated that a preference for \"Using indirect or softened wording\" when delivering bad news was associated with younger age at diagnosis (<20 years), male sex, and shorter time since diagnosis (<5 years). Married participants more often preferred \"Breaking bad news before it is fully confirmed.\"</p><p><strong>Conclusion: </strong>AYA patients generally prefer clear and accurate disclosure of medical information while valuing physicians' consideration for their family members. Many prefer factual information before or alongside emotional support, highlighting the need for flexible, individualized communication strategies.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261450843"},"PeriodicalIF":1.2,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunities to Improve Care for Young Adults with Resectable Extremity Sarcoma: A Qualitative Study Highlighting Age-Specific Barriers.","authors":"Sara P Myers, Alison M Aldrich, Laura J Rush, Mireille Bitangacha, Rachael Hawthorn, Ann Scheck McAlearney, John H Alexander","doi":"10.1177/21565333261455257","DOIUrl":"https://doi.org/10.1177/21565333261455257","url":null,"abstract":"<p><strong>Background: </strong>Sarcomas are rare, heterogeneous malignancies that disproportionately affect adolescents and young adults (AYAs) aged 15-39 years. Despite representing less than 1% of new cancer diagnoses in the United States, sarcoma is a leading cause of mortality in individuals under 20 years old. Although age-specific challenges that may compromise long-term survivorship have been investigated, the specific experiences and perspectives of young adults navigating the sarcoma care continuum remain underexplored.</p><p><strong>Methods: </strong>We conducted a qualitative study using semistructured, web-based interviews with AYAs (18-39 years) who underwent surgical resection for extremity sarcoma at a single comprehensive cancer center, conducting interviews between August 2024 and January 2025. Participants were recruited from an orthopedic oncology clinic and consented electronically. Interviews explored experiences from diagnosis through recovery, including communication, support systems, and perioperative education. Transcripts were analyzed using inductive thematic analysis.</p><p><strong>Results: </strong>In total, 14 participants (64% female) with diverse sarcoma subtypes and treatment histories completed interviews. Themes included (1) diagnostic challenges, such as low clinical suspicion and delays in referral to sarcoma specialists; (2) the critical role of support systems during diagnosis and hospitalization; and (3) communication gaps regarding fertility, financial concerns, postoperative complications, and long-term recovery.</p><p><strong>Conclusions: </strong>AYAs with sarcoma face unique barriers across the care continuum, including delayed diagnosis, limited psychosocial support, and insufficient perioperative education. Interventions to improve early recognition, strengthen referral pathways, enhance communication, and deliver tailored resources are urgently needed. Larger, multicenter studies should validate these findings and inform strategies to optimize outcomes for this vulnerable population.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261455257"},"PeriodicalIF":1.2,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Through Both Lenses: Patient-Clinician Dynamics in Serious Illness Conversations for Young Adults with Advanced Cancer.","authors":"Bethany J Lockwood, Rachael Hawthorn, Laura J Rush, Gennaro Di Tosto, Karen O Moss, Seuli Bose Brill","doi":"10.1177/21565333261451813","DOIUrl":"10.1177/21565333261451813","url":null,"abstract":"<p><strong>Purpose: </strong>Young adults (YAs) with advanced cancer face distinct medical and psychosocial challenges, making high-quality tailored communication essential. Yet the optimal timing and facilitation of serious illness conversations (SIC) remain variable. This study explores YA and multidisciplinary clinician perspectives on experiences with SIC.</p><p><strong>Methods: </strong>Using a prospective, cross-sectional mixed methods design, we surveyed 98 participants 39 YAs aged 18-39 years with advanced disease across cancer types and 59 clinicians across disciplines and cancer specialties. Qualitative data, using basic qualitative description, were integrated to triangulate quantitative findings related to advance care planning (ACP) and palliative care (PC) understanding and to identify SIC barriers, facilitators, and readiness.</p><p><strong>Results: </strong>YAs reported substantial emotional and career/education disruption from cancer. Nearly half (49%) were unsure about ACP, while others linked it with proxy decisions or end-of-life (EOL) planning. Clinicians broadly endorsed similar ACP topics, emphasizing care preferences, code status, and surrogate decision-making. Most YAs (59%) had limited PC knowledge and often equated it with EOL care. Shared SIC barriers included emotional toll and time limits, while a key facilitator was conversation initiation by the other party. Readiness for SIC was tied to emotional acceptance and clinical turning points.</p><p><strong>Conclusion: </strong>YAs with advanced cancer demonstrate varied awareness of ACP, PC, and experiences with SIC. Conversations typically arise at pivotal disease moments, a tipping point, requiring mutual readiness and recognition of changing realities by both patients and clinicians. Earlier and tailored communication may improve concordance of care delivered with YA values and preferences.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451813"},"PeriodicalIF":1.2,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward a Better Understanding of Fear of Cancer Recurrence in Adolescents and Young Adults: Validation of a Theoretical Model.","authors":"Maria Carolina Neves, José A E Custers, Judith B Prins, Filipa Nunes, Sara Monteiro, Célia Sales","doi":"10.1177/21565333261451809","DOIUrl":"https://doi.org/10.1177/21565333261451809","url":null,"abstract":"<p><strong>Purpose: </strong>Theoretical models on fear of cancer recurrence (FCR) have been developed and validated for adult cancer survivors, despite high levels of FCR being found in adolescents and young adults (AYAs). This study intended to empirically validate a model of FCR for AYAs based on the theoretical models of Lee-Jones and Lebel.</p><p><strong>Methods: </strong>One hundred AYAs diagnosed with cancer between the ages of 15 and 25 were included (59% female). Data were collected online and in-person from four hospitals and one association for young cancer patients in Portugal using the Quality of Life (QoL) Questionnaire Core-30, the FCR7 scale, the Emotion Regulation Questionnaire, the 15-item Systematic Clinical Outcome and Routine Evaluation scale, the Satisfaction with Social Support Scale, and the Hospital Anxiety and Depression Scale.</p><p><strong>Results: </strong>A path analysis showed an excellent model fit: χ²(28) = 30, <i>p</i> = 0.363; Bentler comparative fit index (CFI) = 0.99; Tucker-Lewis index = 0.98; root-mean-square error of approximation = 0.03; standardized root-mean-square residual = 0.08. Significant paths were found from FCR to depressive symptoms and QoL, with friends' support moderating the path between FCR and depressive symptoms. Depressive symptoms and QoL were also related to emotion suppression and friends' support.</p><p><strong>Conclusion: </strong>Being satisfied with their friends' support seems to be protective for AYAs with high FCR levels, while satisfaction with family support does not seem to have an influence. This diverges from previous models, supporting the need for a distinct AYA model. Additionally, emotion suppression was related to depression and QoL, but not FCR.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451809"},"PeriodicalIF":1.2,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}