Journal of adolescent and young adult oncology最新文献

{"title":"Influence of Personalized Advice on Cardiovascular Management in Childhood Cancer Survivors.","authors":"Léa Frémont, Léonie Casagranda, Hélène Sudour-Bonnange, Catherine Massoubre, Jean-Hugues Dalle, Cecile Teinturier, Pascale Guillot, Virginie Lanlo, Bernard Dal Molin, Michèle Dal Molin, Arnauld Garcin, Brice Fresneau, Claire Poulalhon, Charlotte Demoor-Goldschmidt, Claire Berger","doi":"10.1177/21565333261454210","DOIUrl":"https://doi.org/10.1177/21565333261454210","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the cardiovascular medical management of young adults who had viewed the massive open online course (MOOC) \"Childhood Cancer, Living Well, After\" four years earlier during the feasibility study (START-MOOC1), compared with those who had not.</p><p><strong>Methods: </strong>A retrospective, descriptive, French multicenter study was conducted involving 322 childhood cancer survivors (CCS) (range, 20-36 years) eligible to view the cardiovascular health module of the MOOC. Participants were divided into two groups those who had viewed the MOOC (MOOC+) four years earlier and those who had not (MOOC-). We collected data on medical follow-up, cardiovascular care, and lifestyle habits using a short questionnaire. We analyzed it using descriptive statistics and comparative tests.</p><p><strong>Results: </strong>Of the 322 eligible CCS, 95 completed the questionnaire (34 MOOC+ and 61 MOOC-). The participation rate was significantly higher in the MOOC+ group (55.7% vs. 23.4%, <i>p</i> < 0.0001). We found no significant difference between the groups regarding general medical care and cardiologist follow-up. However, 20% of MOOC+ participants began cardiological follow-up after the MOOC, 15% increased their physical activity, and 6% improved their diet. In addition, 25% of MOOC+ participants began complementary therapies.</p><p><strong>Conclusion: </strong>The MOOC \"Childhood Cancer, Living Well, After\" did not result in any significant difference in cardiovascular follow-up behaviors compared with patients who did not view the MOOC. However, the MOOC+ group promoted positive lifestyle changes. Further research with a larger cohort is necessary to assess the full impact of the MOOC on the long-term medical follow-up.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261454210"},"PeriodicalIF":1.2,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collaborative Multidisciplinary Teamwork in the Care of Adolescent and Young Adult Patients with Cancer: A Systematic Review.","authors":"Hyewon Shin, Angela Kabbe, Jennie C De Gagne","doi":"10.1177/21565333261451978","DOIUrl":"https://doi.org/10.1177/21565333261451978","url":null,"abstract":"<p><strong>Objective: </strong>Adolescents and young adults (AYAs) with cancer face unique developmental, psychosocial, and care transition challenges between pediatric and adult oncology systems. Multidisciplinary team (MDT) approaches are promoted to address these complex needs; however, collaboration, implementation, and impact on AYA care remain inconsistently described in the literature. This systematic review synthesizes evidence on how MDTs are organized, enacted, and experienced in AYA oncology care and examines implications for patient-centered, developmentally appropriate care.</p><p><strong>Methods: </strong>Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, a search of CINAHL, PsycINFO, and PubMed was conducted for studies published between January 2000 and March 2025. Eligible studies were peer-reviewed articles in English involving participants aged 15-39 years with cancer who addressed survivorship and multidisciplinary teamwork. Of 1048 screened records, 15 studies met the inclusion criteria and were included in the synthesis.</p><p><strong>Results: </strong>Four overarching themes were identified: (1) core elements of effective MDT collaboration, including flexible professional roles, MDT communication, and shared decision-making with AYAs; (2) addressing the unique psychosocial and developmental needs of AYAs, supporting care coordination, and psychosocial support; (3) implementation and functions of MDTs across the AYA cancer care continuum, facilitating smoother transitions between pediatric and adult services; and (4) the impact of MDT care on patient outcomes, including improved adherence to follow-up care and enhanced psychosocial well-being.</p><p><strong>Conclusion: </strong>Evidence shows MDTs function as relational processes shaping AYA cancer care quality, not just organizational structures. Effective MDTs emphasize patient-centered collaboration and multidisciplinary trust across the cancer trajectory. Future research should evaluate how MDT processes influence clinical, psychosocial, and survivorship outcomes for AYA.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451978"},"PeriodicalIF":1.2,"publicationDate":"2026-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148005292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linking Qualitative Mindfulness Reflections During MBSR to Meaningful Improvement in PROMIS Scores in a Young Adult Cancer Survivor Sample: The Role of Bodily Awareness.","authors":"Karen Llave, Christina Sauer, Shruti Parthasarathy, Carly Maletich, Bruriah Horowitz, Stacy Sanford, David Victorson","doi":"10.1177/21565333261451812","DOIUrl":"https://doi.org/10.1177/21565333261451812","url":null,"abstract":"<p><strong>Purpose: </strong>Young adult cancer survivors (YACS; 18-39 years old) face ongoing physical and psychosocial sequelae. The REDEFINE study tested the feasibility of mindfulness-based stress reduction (MBSR) using a randomized design. This secondary mixed-methods analysis examined whether qualitative mindfulness reflections were associated with meaningful changes in Patient Reported Outcomes Measurement Information System (PROMIS) depression, anxiety, fatigue, and pain interference scores.</p><p><strong>Methods: </strong>Participants were randomized to either an 8-week MBSR course or a waitlist control group. Waitlist participants began MBSR after 16 weeks. PROMIS measures were collected at baseline and at 8, 16, 24, and 32 weeks. For these analyses, data from both groups were combined. Participants submitted written mid-course and weekly homework reflections on their mindfulness experiences. Change scores were calculated between PROMIS T-scores at the start and end of MBSR and were assessed for meaningful change. Reflections were coded using grounded theory, and a concurrent triangulation mixed-methods design integrated qualitative and quantitative data.</p><p><strong>Results: </strong>Among 31 participants (mean age, 32.6 ± 5.8 years; 83.9% female, White, and non-Hispanic), nearly half reported meaningful improvement in pain interference (48.3%) and fatigue (48.3%), while more than half improved in depression (51.7%) and anxiety (58.6%). Mixed-methods analysis linked improvements in pain, depression, and anxiety with reflections describing increased bodily awareness, a more positive relationship with the body, and learning mindfulness skills.</p><p><strong>Conclusions: </strong>MBSR-related mind-body reflections align with meaningful improvements in psychosocial and physical symptoms among YACS. Reports of bodily relaxation and emotional regulation suggest the value of combining structured and unstructured patient-reported outcomes to capture the benefits of mindfulness interventions.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451812"},"PeriodicalIF":1.2,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Nerves Speak Louder Than Words: Polyneuropathy and Multisystem Involvement in a Teenager.","authors":"Courtney S Pugh, Casey McCaffrey, Christina Chen","doi":"10.1177/21565333261451817","DOIUrl":"https://doi.org/10.1177/21565333261451817","url":null,"abstract":"<p><p>POEMS syndrome is a rare plasma cell disorder that is characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes, most commonly affecting middle-aged men. Due to its rarity and clinical overlap with other conditions, diagnosis relies on established mandatory, major, and minor criteria. We report a case of POEMS syndrome in a 17-year-old female. This case contributes to the limited literature on pediatric and adolescent presentations of POEMS syndrome and underscores clinical features that may aid in earlier recognition and diagnosis.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451817"},"PeriodicalIF":1.2,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Insurance Literacy and Financial Toxicity in Adolescent and Young Adult Cancer Survivors.","authors":"Jean Edward, Amanda Wiggins, Mackenzie Caldwell, Louis Baser, Kimberly D Northrip, John D'Orazio","doi":"10.1177/21565333261451816","DOIUrl":"10.1177/21565333261451816","url":null,"abstract":"<p><strong>Purpose: </strong>Empirical evidence examining the impact of health insurance literacy (HIL) on cancer-related financial toxicity (FT) among adolescent and young adults (AYAs) is limited. AYA cancer survivors experience greater levels of financial hardship due to sociodemographic and developmentally related factors. The purpose of this study was to examine the relationship between HIL and FT in this vulnerable population.</p><p><strong>Methods: </strong>We used a cross-sectional design to survey 246 AYA cancer survivors (diagnosed between ages 15-39) through the Kentucky Cancer Registry (KCR). Survey data were collected on FT and HIL using the Health Insurance Literacy Scale (HILS) and Health Insurance Literacy Measure (HILM) subscales on behaviors related to choosing and using health insurance plans. Record-level KCR data included county of residence and race/ethnicity among other sociodemographic variables.</p><p><strong>Results: </strong>Two-thirds (67%) of participants indicated experiencing problems with understanding health insurance or medical bills. When adjusting for sociodemographic variables, those with inadequate HILS scores reporting higher (<i>p</i> = 0.002) FT scores than those with adequate HILS (<i>b</i> = 0.05, SE = 0.02). An inverse relationship (<i>p</i> = 0.042) was found between behaviors related to choosing health insurance plans and FT (<i>b</i> = -0.003, SE = 0.002). A significantly (<i>p</i> = 0.028) lower proportion of rural participants had adequate HILS scores (55%), compared to their urban counterparts (71%).</p><p><strong>Conclusion: </strong>Our findings highlight the need for integrating HIL education and resources in FT interventions tailored to address the unique needs of geographically diverse AYA cancer survivors across the cancer continuum.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261451816"},"PeriodicalIF":1.2,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of End-of-Life Care for Adolescent and Young Adult Patients with Cancer and Depression and Grief in Bereaved Families: A Secondary Analysis.","authors":"Mitsunori Miyashita, Anni Fu, Satomi Ito, Lei Dong, Yoko Nakazawa, Masanori Mori, Chikako Shimizu","doi":"10.1177/21565333261450799","DOIUrl":"https://doi.org/10.1177/21565333261450799","url":null,"abstract":"<p><strong>Background: </strong>Adolescent and young adult (AYA) patients with cancer face numerous challenges, particularly at the end-of-life. However, little is known about how the patients and their families experience end-of-life care.</p><p><strong>Objective: </strong>We aimed to compare the quality of end-of-life palliative care and the levels of depression and grief among bereaved families of AYAs and middle-aged patients with cancer, and to identify associated factors.</p><p><strong>Methods: </strong>We conducted a secondary analysis of a nationwide mortality follow-back survey based on death certificates of patients who died from cancer in 2017 and 2018. Subjects were classified into two groups AYA (aged 20-39 years) and the middle-aged (aged 40-64 years). End-of-life quality was evaluated using the Care Evaluation Scale, Good Death Inventory, and Memorial Symptom Assessment Scale. Depression and grief levels among bereaved family members were also evaluated.</p><p><strong>Results: </strong>We analyzed 261 and 5790 bereaved families from the AYA and middle-aged groups, respectively. While the quality of end-of-life palliative care did not differ clinically significantly between the AYA and middle-aged group, the levels of grief and depression were significantly higher in the AYA compared with the middle-aged group (Effect Size [ES] = 0.57, <i>p</i> < 0.0001; ES = 0.22, <i>p</i> = 0.001, respectively).</p><p><strong>Conclusion: </strong>Although end-of-life care quality was comparable between AYAs and middle-aged patients, bereaved families of AYA patients experienced significantly greater grief and depression. These findings underscore the need for tailored bereavement support for AYA families.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261450799"},"PeriodicalIF":1.2,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147929822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disordered Eating Behaviors in Young Adult Cancer Survivors: A Cross-Sectional Analysis.","authors":"Ana Paula S Rodrigues, Acadia W Buro, Nashira I Brown, Tiffany L Carson, Marilyn Stern","doi":"10.1177/21565333261450802","DOIUrl":"10.1177/21565333261450802","url":null,"abstract":"<p><p>Disordered eating behaviors pose significant health risks, yet evidence among young adult (YA) cancer survivors is limited. We examined the prevalence and associated factors of disordered eating attitudes and binge eating symptoms in YA survivors (18-39 years). Participants (<i>n</i> = 173) completed surveys assessing eating attitudes and behaviors, food security, and demographics. Briefly, 21.5% reported high concern for disordered eating attitudes, and 26.6% had moderate-severe binge eating risk. Both outcomes were significantly associated with weight-related concerns (β = 0.45 and β = 0.46) and socioeconomic advantage (β = 0.31 and β = 0.22). Food insecurity predicted higher binge eating (β = 0.22). Screening, education, and resource provision in survivorship care are needed.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261450802"},"PeriodicalIF":1.6,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trunk Muscle Mass Changes During Chemotherapy in Children and Adolescents with Lower-Limb Osteosarcoma: A Retrospective Study Comparing Surgical Procedures.","authors":"Masahiro Aoki, Megumi Toki, Takanori Murakami, Makoto Emori","doi":"10.1177/21565333261449926","DOIUrl":"https://doi.org/10.1177/21565333261449926","url":null,"abstract":"<p><strong>Purpose: </strong>To examine longitudinal changes in trunk muscle mass during chemotherapy in children and adolescents with lower-limb osteosarcoma and to compare these changes according to surgical procedure.</p><p><strong>Methods: </strong>Medical records of 11 patients admitted to a university hospital in Japan between 2010 and 2023 were analyzed. Trunk muscle mass was assessed using computed tomography scans of the L3 vertebral body using the VINCENT^® abdominal analysis system. Changes in trunk muscle mass from admission to discharge were categorized as increase (≥5%), maintenance (±5%), or decrease (≤-5%). Rehabilitation-related variables and surgical procedures were examined in relation to muscle mass changes.</p><p><strong>Results: </strong>The mean age was 13.7 years (eight males and three females). Seven patients underwent limb-sparing surgery, and four underwent amputation. No significant associations were observed between rehabilitation-related variables (hospitalization duration, rehabilitation frequency, or session duration) and trunk muscle mass changes. However, a significant association was identified between surgical procedure and trunk muscle mass changes. All patients who underwent amputation maintained or increased muscle mass, whereas five of the seven patients who underwent limb-sparing surgery experienced a decrease.</p><p><strong>Conclusion: </strong>In this retrospective observational study, trunk muscle mass changes during chemotherapy were associated with the type of surgical procedure but not with rehabilitation-related variables. Further studies with larger sample sizes are warranted to better understand factors associated with muscle mass changes in this population.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261449926"},"PeriodicalIF":1.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Discussion to Action: Mapping the Oncofertility Referral Gap in Indian Breast Cancer Care.","authors":"Balasubramanian Venkitaraman, Sathyanarayanan M Shivkumaran, Lakshmi Jayachandran Susheela, Prithviraj Premkumar, Suhaildeen Kajamohideen","doi":"10.1177/21565333261445405","DOIUrl":"https://doi.org/10.1177/21565333261445405","url":null,"abstract":"<p><strong>Purpose: </strong>There is an increase in the incidence of breast cancer in young Indian women. With better oncological care leading to improved survival rates, fertility preservation (FP) has become an important part.</p><p><strong>Methods: </strong>A cross-sectional survey done across oncologists in India. The questionnaire included questions on their demographics and questions on knowledge of oncofertility, attitude toward discussing FP, and their current clinical practices. We used descriptive statistics to analyze the data using SPSS software.</p><p><strong>Results: </strong>A total of 123 oncologists completed the questionnaire. Most of them were surgical oncologists (68.3%). The majority (55%) had 3-10 years of experience, working in metropolitan areas (60%), and at teaching hospitals (58%). Their knowledge of oncofertility was assessed to be good. They also had a very positive attitude, with 89% being comfortable in discussing FP with their patients. However, we found a big gap, with nearly half (47%) of the oncologists saying that less than 25% of their patients ask questions pertaining to fertility. Only 22.8% of the oncologists had successfully referred at least one patient for a fertility consultation. This shows a large gap between knowledge of oncologists and actual discussion and final outcomes.</p><p><strong>Conclusion: </strong>Indian oncologists appear to have a sound knowledge and a positive attitude; however, there is a major gap between their awareness and what happens in practice. The main problem seems to be patient's perspective with patients not willing or not able to pursue these options, even when they are made aware about them.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261445405"},"PeriodicalIF":1.2,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distress in Adolescent and Young Adult Patients with Cancer: Age- and Gender-Related Differences in a Retrospective Screening Study.","authors":"Takako Ikegami, Naho Matsubara, Hiroto Ishiki, Mana Ota, Ayana Hirose, Ayaka Ishikawa, Rumi Nishimura, Naruaki Kawasaki, Sayaka Arakawa, Yuki Kojima, Takatoshi Hirayama, Ryoko Udagawa, Naoko Inamura, Takuma Koinuma, Takashi Kawaguchi, Yusuke Hori, Eriko Satomi","doi":"10.1177/21565333261445410","DOIUrl":"https://doi.org/10.1177/21565333261445410","url":null,"abstract":"<p><strong>Background: </strong>Adolescent and young adult (AYA) patients with cancer frequently experience psychosocial distress, yet age- and gender-related differences in distress in routine care are not fully understood.</p><p><strong>Purpose: </strong>To examine age- and gender-related differences in distress and specific psychosocial concerns among AYA patients with cancer using routine distress screening.</p><p><strong>Methods: </strong>This retrospective single-center study included AYA patients aged 15-39 years who completed distress screening with the Distress Thermometer (DT) and problem checklist prior to first-line cancer treatment. Clinically significant distress was defined as DT ≥ 4 based on NCCN guidelines and institutional practice. Distress levels and checklist items were compared across age groups (teens, 20s, 30s), gender, cancer stage, and time from diagnosis to screening.</p><p><strong>Results: </strong>Among 213 patients, clinically significant distress (DT ≥ 4) was more frequent among teenage males than among males in their 30s. Female patients reported more emotional concerns across all ages, while fertility-related concerns were reported by both males and females. Financial concerns, reflecting financial toxicity, were most common among patients in their 30s and those with advanced-stage disease. A shorter interval between diagnosis and screening was associated with higher distress levels.</p><p><strong>Conclusions: </strong>Using the standard DT cutoff of ≥4, distress among AYA patients with cancer varied significantly by age and gender. Teenage males represented a particularly vulnerable group with elevated distress at diagnosis, while financial toxicity was a major concern among patients in their 30s. These findings emphasize the need for early, age- and gender-tailored psychosocial screening and support in AYA oncology care.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261445410"},"PeriodicalIF":1.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}