Journal of adolescent and young adult oncology最新文献

{"title":"A Study on the Timing of Resumption of Menstruation After Interruption/Termination of GnRH Agonist Therapy in Premenopausal Breast Cancer Patients.","authors":"Kahori Takei, Haipeng Huang, Hazuki Sato, Soichiro Kashiwabara, Kouki Samejima, Shigetaka Matsunaga, Yasushi Takai","doi":"10.1177/21565333251394139","DOIUrl":"10.1177/21565333251394139","url":null,"abstract":"<p><strong>Purpose: </strong>In hormone therapy for premenopausal breast cancer (BC), gonadotropin-releasing hormone (GnRH) agonist (GnRHa) formulations, especially long-acting formulations, are often used in combination with tamoxifen (TAM). On the other hand, in recent years, endocrine therapy is increasingly interrupted to achieve pregnancy. Here, we examined ovarian function and the timing of resumption of menstruation after the interruption of GnRHa therapy.</p><p><strong>Methods: </strong>Fertility preservation patients with BC who visited our hospital between January 2010 and August 2023 and who interrupted endocrine therapy with a GnRHa formulation were included. Information on 22 cases (24 cycles), including two interruptions due to the desire for a second child, was collected from medical records and examined retrospectively.</p><p><strong>Results: </strong>Three cases started assisted reproductive technology treatments before menstruation resumed and were excluded from the analysis. Menstruation resumed at approximately 7, 9, and 12 months from the last dose of the 1-, 3-, and 6-month GnRHa formulations, respectively. The long delay of menstruation resumption was presumably caused by the use of (1) the 3-month formulation in the 6 months before the last GnRHa dose, (2) the 6-month formulation in the 12 months before the last dose, and (3) TAM when menstruation resumed.</p><p><strong>Conclusions: </strong>In BC patients who may seek pregnancy after interrupting endocrine therapy, it may be easier to estimate the timing of resumption of menstruation if the use of long-term GnRHa depot formulations is avoided for >6 months before the interruption. BC endocrine therapy should be optimized to achieve pregnancy and childbirth as soon as possible during its interruption.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"328-333"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Work Ability in Young Adult Survivors (WAYS WF-10217): Documenting Labor Force Participation, Occupation, and Educational Attainment Following Cancer Treatment.","authors":"Karly M Ingram, Janet A Tooze, Sharon M Castellino, Katherine A McLean, John M Salsman, Lauren V Ghazal, Heather Miller, James Lloyd Wade, Robert J Behrens, Joanne C Sandberg, Carla Strom, Thomas A Arcury, Glenn J Lesser, Suzanne C Danhauer","doi":"10.1177/21565333261418478","DOIUrl":"10.1177/21565333261418478","url":null,"abstract":"<p><strong>Purpose: </strong>Work ability and work-related outcomes (labor force participation, occupation, and educational attainment) are important for young adult-aged survivors of adolescent and young adult cancer (YAs). This study evaluates work-related outcomes and explores the role of workplace accommodations among YAs aged 25-34 years.</p><p><strong>Methods: </strong>For this cross-sectional study, YAs (<i>N</i> = 209) completed measures of educational attainment, labor force participation, occupation, work ability, and workplace accommodations. Work ability was assessed using the Work Ability Index and Work Limitations Questionnaire productivity loss index. We compared work-related outcomes with national benchmarks; analysis of variance models examined associations among work ability, work-related outcomes, and workplace accommodations.</p><p><strong>Results: </strong>Participant education and employment were greater than national benchmarks. Among employed cancer survivors (<i>N</i> = 176), individuals with less education reported lower work ability (<i>F</i> = 3.99, <i>p</i> = 0.004) and greater productivity loss (<i>F</i> = 4.21, <i>p</i> = 0.003) than those with higher levels of education. Workplace accommodations were a significant predictor of work ability; those with accommodations reported lower work ability (<i>F</i> = 3.99, <i>p</i> = 0.004) and greater productivity loss (<i>F</i> = 4.21, <i>p</i> = 0.003).</p><p><strong>Conclusions: </strong>While YAs in this sample generally demonstrated higher employment and educational attainment rates than the national average, those with lower educational levels face greater challenges in work ability. Workplace accommodations may only be provided to individuals experiencing the greatest deficits in work ability and productivity. This study highlights the need for additional data regarding workplace accommodations to enhance work ability and mitigate productivity loss among YAs.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"368-377"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disrupted Independence-Supporting Adolescents and Young Adults with Sarcoma in Maintaining Autonomy: A Qualitative Study.","authors":"Vinayak Venkataraman, Bridgette Merriman, Anna Revette, Brett Nava-Coulter, Suzanne George, David S Shulman, Katie A Greenzang","doi":"10.1177/21565333251397787","DOIUrl":"10.1177/21565333251397787","url":null,"abstract":"<p><strong>Purpose: </strong>Adolescents and young adults (AYAs; 15-39 years) with sarcoma undergo intensive therapies during a vulnerable time in their lives. We aimed to characterize the unmet needs of AYAs with sarcoma to inform strategies that improve outcomes.</p><p><strong>Methods: </strong>We used purposive sampling to conduct semistructured focus groups of AYAs with sarcoma treated primarily at Dana-Farber Cancer Institute. Focus groups were conducted via Zoom by trained moderators and focused on experiences with treatment, decision-making, care communication, supportive care services, and the effects of cancer on daily life. Focus groups were audio recorded, transcribed, and thematically analyzed via a team-based approach.</p><p><strong>Results: </strong>We conducted four focus groups with 20 participants (16-34 years) adolescents, emerging adults, young adults, and those with recurrent/metastatic disease. Participants confirmed that sarcoma and its treatment affected their physical, emotional, social, and economic health. We identified three key overarching themes: (1) Disruption to agency and mobility negatively impacted well-being and social relations; (2) The transition from \"active treatment\" to \"surveillance\" was fraught as it often magnified challenges of \"returning to normal\" and loss of autonomy; and (3) Additional supports and services may help address identified unmet needs and gaps in care. Participants expressed a desire for support services to be introduced earlier to help facilitate independence.</p><p><strong>Conclusion: </strong>AYAs with sarcoma experience loss of agency, mobility, and impaired well-being due to their diagnoses and treatments. They desire early introduction of supportive services, and care teams can proactively address these challenges by connecting patients with targeted services, resources, tools, and community.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"319-327"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145573790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing a User-Centered Design to Develop a Web-Based Sperm Banking Decision Tool for Adolescent Males with Cancer.","authors":"Megan M Griffith, Emre Sezgin, Tanvi Karkare, Charleen I Roche, Jennifer English, Anthony Audino, Kathleen E Montgomery, Amanda J Saraf, Gwendolyn P Quinn, Ashley J Housten, Michael Scherer, Megan Scherer, Leena Nahata","doi":"10.1177/21565333251398494","DOIUrl":"10.1177/21565333251398494","url":null,"abstract":"<p><strong>Purpose: </strong>Approximately half of male childhood cancer survivors experience treatment-related fertility impairment. Regrets about missed sperm banking opportunities have been reported, yet few decision tools for male adolescents with cancer exist. This study aims to report the development, testing, and adaptation of the Family-centered Adolescent Sperm banking values clarification Tool (FAST) using an iterative, user-centered design with male adolescents with cancer and their caregivers and to obtain feedback from clinicians and community partners.</p><p><strong>Methods: </strong>Males (12-25 years, diagnosed with cancer in the past year, received a routine fertility consult where sperm banking was offered) and caregivers completed the FAST on a screen-recorded device, a semi-structured interview, the System Usability Scale (SUS), and a sociodemographic questionnaire. Feedback informed FAST adaptations and was documented using the Framework for Reporting Adaptations and Modifications-Expanded. Descriptive statistics and thematic analysis characterized FAST completion information.</p><p><strong>Results: </strong>Ten families (16 caregivers, 9 adolescents) enrolled. Themes included: ease of navigation, perceived usefulness of the FAST, and perspectives on tool adaptations. Forty-three FAST adaptations were made in response to participant feedback. Median FAST completion time was 5 minutes and 37 seconds. The mean FAST SUS score was high at 84.60 (minimum = 57.50, maximum = 100, standard deviation = 11.08).</p><p><strong>Conclusions: </strong>Applying an iterative, user-centered approach, the FAST was developed, usability-tested, and adapted to a web-based format that families found easy to navigate and useful. Web-based tools, such as the FAST, could improve the sperm banking decision-making process for adolescent males and their caregivers by addressing unmet needs and ultimately improving satisfaction with fertility counseling outcomes.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"311-318"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13244301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145563750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eating Experiences During Cancer Treatment in Adolescents and Young Adults: A Systematic Literature Review and Meta-Synthesis.","authors":"Marie Ernst Christensen, Rakel B Jónsdóttir, Sigrún Sunna Skúladóttir, Marianne Elisabeth Klinke","doi":"10.1177/21565333251412395","DOIUrl":"10.1177/21565333251412395","url":null,"abstract":"<p><p>Adolescents and young adults (AYAs) aged 15-39 with cancer face distinct challenges during treatment, with eating consistently emerging as one of the most distressing and underrecognized concerns. At a critical life stage, AYAs must navigate illness-related consequences that profoundly affect well-being. Eating reflects these broader challenges and is identified as a key issue requiring health care attention. To address this, we synthesized evidence on AYAs' eating experiences and well-being during mealtime-related activities to inform health care practice. Qualitative and mixed-method studies were identified through searches across CINAHL, Embase, PubMed, Scopus, and Web of Science for studies published up to May 2025, supplemented by snowball searches. Of 3214 records, 74 full-text articles were reviewed, and 18 met the inclusion criteria. These represented 302 AYAs, 73 relatives, and 88 health care professionals. Studies were analyzed using Joanna Briggs Institute review methods and GRADE-CERQual to support clinical interpretability. The meta-synthesis identified one core theme: \"Eating as an embodied struggle and act of agency,\" with three subthemes: (a) living through physical and sensory disruption, (b) carrying the weight of new emotions and shifting relations, and (c) finding ways through gaps in support. Eating emerged as a disrupted, emotionally charged, yet agentic act requiring sensitive, individualized approaches. Thirteen evidence-informed recommendations were developed to guide clinical application. These emphasize early nutritional screening, dietetic support, flexible meal options, respectful family involvement, and psychosocially attuned care. Future research should codevelop and evaluate tailored interventions that address AYAs' embodied, emotional, and social needs to improve eating-related quality of life during cancer treatment.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":"15 5","pages":"277-298"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Acceptability of an Age-Specific Multidimensional Rehabilitation Program for Young Adult Cancer Survivors: A Qualitative Feasibility Study.","authors":"Maria Aagesen, Marc Sampedro Pilegaard, Dorthe Søsted Jørgesen, May Aasebø Hauken, Karen la Cour","doi":"10.1177/21565333261416758","DOIUrl":"10.1177/21565333261416758","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the acceptability of the content and delivery of the age-specific cancer rehabilitation program Young Adults Taking Action (YATAC) from the perspective of young adult cancer survivors (YACSs).</p><p><strong>Methods: </strong>Nineteen YACSs (aged 18-39) participated. Program acceptability was explored through four focus groups. The Theoretical Framework of Acceptability guided data collection and analysis. Data from the focus groups were deductively analyzed using framework analysis.</p><p><strong>Results: </strong>The YACSs found the YATAC program acceptable and relevant to their needs. The participants reported enhanced physical self-efficacy, improved mood, greater acceptance of their condition, reduced loneliness, and increased confidence in managing daily life. Peer support, practical exercises, and tailored content were identified as particularly valuable. Referring to delivery acceptance, participants described the program format as engaging and supportive, though some found the intensive schedule burdensome. Few suggested removing content; instead, they recommended extending sessions and adding topics such as diet, fertility, and cognitive concerns. The participants also highlighted the need for clearer guidance on accessing resources after the program. Group discussions were generally beneficial; however, some participants expressed discomfort around discussing sensitive topics in mixed settings.</p><p><strong>Conclusion: </strong>The YATAC program was well received and perceived as beneficial by YACSs, particularly when sessions were practical, peer-supported, and individualized. The findings support the program's continued development and refinement.</p><p><strong>Implications for cancer survivors: </strong>This study highlights the importance of peer interaction and personalized content and thoughtful delivery design in survivorship care for young adults. Future research should explore long-term and wider outcomes.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"347-357"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review of Health Insurance and Survival Among Adolescent and Young Adult Cancer Patients.","authors":"Tara Martin, Rhonda Winegar, Zhaoli Liu","doi":"10.1177/21565333261417655","DOIUrl":"10.1177/21565333261417655","url":null,"abstract":"<p><p>Cancer is the leading cause of disease-related death among female adolescents and young adults (AYAs) and the second leading cause after heart disease among males in the United States. Despite recent improvements in survival outcomes, AYAs continue to experience poorer cancer survival rates compared with pediatric and older adult populations. Health care access and quality are substantially influenced by insurance coverage, and AYAs represent the age group with the highest proportion of uninsured individuals. The objective of this review was to examine the association between insurance status and cancer survival among AYAs to inform future policy interventions. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, peer-reviewed studies published in the United States between 2018 and 2024 were identified from PubMed, CINAHL, and Web of Science. Eligible studies examined associations between insurance status and survival outcomes among the AYA cancer population. Ten studies, encompassing 468,583 AYAs with cancer (60.1% female), were included. Individuals with Medicaid/public insurance, as well as those uninsured, exhibited poorer survival outcomes compared with those privately insured across multiple cancer types, including head and neck cancer, lymphoma, central nervous system tumors, hepatic carcinomas, sarcoma, germ cell, breast, thyroid, cervical, colorectal, uterine, ovarian, kidney, lung, and melanoma. Several associations appeared to be age-dependent (e.g., lymphoma). Findings from this review suggest that insurance status is associated with both short- and long-term cancer outcomes among AYAs. The results also highlight persistent challenges in accurately assessing and categorizing insurance status within this population.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"299-310"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult Survivors of Childhood Cancer Unmet Needs: A Quality Improvement Brief Report.","authors":"Dori M Beeler, Susan Yaguda, Jennifer Pope","doi":"10.1177/21565333251407898","DOIUrl":"10.1177/21565333251407898","url":null,"abstract":"<p><p>Childhood cancer survivors (CCS) who completed treatment and are disease-free face long-term care transition challenges. This quality improvement (QI) study explored CCS needs and captured feedback for the Adult Survivors of Childhood Cancer Clinic (ASCC) program development. Participants were predominantly White and female; ages ranged from 1 to 17 years at diagnosis and 18 to 34 years at the time of the study. Surveys (n = 47) and interviews (n = 5) focused on the voice of the ASCC patient. REDCap facilitated descriptive survey analysis, while the rapid analysis of interviews identified high-level themes aligned with the survey findings. Nutrition and mental health needs were ranked equally as the top needs, and rapid interview analysis identified noteworthy gender-specific trends. Integrating the patient perspective helps ensure clinic programming is tailored to the patients it serves.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"384-388"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145856165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Predicts Next-Day Fatigue in Adolescents and Young Adults Receiving Maintenance Treatment for Acute Lymphoblastic Leukemia.","authors":"Kimberly L Klages, Ahna L H Pai, Alexandra M Psihogios","doi":"10.1177/21565333251406895","DOIUrl":"10.1177/21565333251406895","url":null,"abstract":"<p><strong>Objective: </strong>Fatigue is a prevalent and debilitating problem in adolescents and young adults (AYAs) with cancer. AYAs with acute lymphoblastic leukemia (ALL) are at particular risk for fatigue. Other factors, such as pain, nausea, and negative mood, have also been identified as contributors to cancer-related fatigue in cross-sectional studies. Because these states rapidly fluctuate, they may also serve as important time-varying predictors of fatigue. The purpose of this study was to determine whether current pain, nausea, and negative mood predict subsequent fatigue in AYAs during maintenance therapy and whether these relationships are moderated by sociodemographic factors.</p><p><strong>Methods: </strong>Eighteen AYAs (<i>M</i>_age = 17.90) completed a baseline demographic questionnaire and once-daily diaries to assess current fatigue, pain, nausea, and negative mood over a 28-day period during maintenance treatment. Dynamic structural equation modeling was used to examine whether pain, nausea, or negative mood predicts next-day fatigue, and if specific demographic variables, age, biological sex, race, ethnicity, and insurance status (public vs. private) moderated these relationships.</p><p><strong>Results: </strong>Pain significantly predicted next-day fatigue in AYAs (<i>Est.</i> = 0.35, <i>p</i> < 0.001), and age was the only significant moderator of this relationship (<i>Est.</i> = -0.13, <i>p</i> < 0.001). Nausea and negative mood did not significantly predict next-day fatigue.</p><p><strong>Conclusions: </strong>Pain positively predicted next-day fatigue, and the effect of pain as a predictor of fatigue was found to decrease with age. Routine pain assessments that trigger timely, in-the-moment interventions may help alleviate current pain and reduce near-term fatigue in AYAs with ALL during maintenance treatment, especially among younger adolescents.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"334-339"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145833904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Test-Retest Reliability and Mode Effects on Single-Item and Multi-Item Measures in a Survey of Adolescent and Young Adults with Cancer.","authors":"Salene M W Jones, Theresa H M Keegan, Erin E Hahn, Hazel B Nichols, Ellen S O'Meara, Marlaine Figueroa Gray, Karen J Wernli, Candice A M Sauder, Anne C Kirchhoff, Cecile A Laurent, Lawrence H Kushi, Jessica Chubak","doi":"10.1177/21565333251414792","DOIUrl":"10.1177/21565333251414792","url":null,"abstract":"<p><strong>Purpose: </strong>This project examined test-retest reliability and survey mode administration across single-item and multi-item measures among adolescent and young adult (AYA) cancer survivors.</p><p><strong>Methods: </strong>Forty-six AYAs randomly assigned to survey mode (phone, online, and paper) completed the survey and were invited to complete the survey again 1 week later.</p><p><strong>Results: </strong>Mode effects were found on 6% of single-items and 25% of multi-item scores. Reliability was low for 52% of single-items and 8% of multi-item scores.</p><p><strong>Conclusion: </strong>Multi-item measures should generally be used over single-item measures due to better reliability, but single-item measures may be preferable when mode effects are large.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"340-346"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13323965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}