Journal of adolescent and young adult oncology最新文献

{"title":"Test-Retest Reliability and Mode Effects on Single-Item and Multi-Item Measures in a Survey of Adolescent and Young Adults with Cancer.","authors":"Salene M W Jones, Theresa H M Keegan, Erin E Hahn, Hazel B Nichols, Ellen S O'Meara, Marlaine Figueroa Gray, Karen J Wernli, Candice A M Sauder, Anne C Kirchhoff, Cecile A Laurent, Lawrence H Kushi, Jessica Chubak","doi":"10.1177/21565333251414792","DOIUrl":"10.1177/21565333251414792","url":null,"abstract":"<p><strong>Purpose: </strong>This project examined test-retest reliability and survey mode administration across single-item and multi-item measures among adolescent and young adult (AYA) cancer survivors.</p><p><strong>Methods: </strong>Forty-six AYAs randomly assigned to survey mode (phone, online, and paper) completed the survey and were invited to complete the survey again 1 week later.</p><p><strong>Results: </strong>Mode effects were found on 6% of single-items and 25% of multi-item scores. Reliability was low for 52% of single-items and 8% of multi-item scores.</p><p><strong>Conclusion: </strong>Multi-item measures should generally be used over single-item measures due to better reliability, but single-item measures may be preferable when mode effects are large.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"340-346"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13323965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to Care and Opportunities for Improvement: Adolescents and Young Adults with Cancer in Central America, Mexico, the Caribbean, and Peru.","authors":"Elysia M Alvarez, Renata Abrahão, Samantha Wong, Emily Johnston, Crystal Romero, Wendy Gómez García, Daniel Ortiz Morales, Federico Antillon-Klussmann, Soad Fuentes-Alabi, Ligia Fu, Ligia Rios, Karina Quintero Delgado, Pascale Yola Heurtelou Gassant, Melissa Gosdin, Marcio Malogolowkin, Paola Friedrich","doi":"10.1177/21565333261417885","DOIUrl":"10.1177/21565333261417885","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the barriers to care and resources needed for adolescents and young adults (AYAs, 15-39) with cancer in low- and middle-income countries, where most of these patients live. We aimed to address this gap through interviews with pediatric and adult hematologists/oncologists.</p><p><strong>Methods: </strong>We enrolled physicians from nine countries in Central America, Mexico, the Caribbean, and Peru. Semistructured interviews were conducted in Spanish, recorded, transcribed, and translated into English.</p><p><strong>Results: </strong>Twenty-eight respondents provided over 26 hours of data, and 46% were adult hematologists/oncologists. We identified multiple barriers in caring for AYA patients, including clinical, psychosocial, financial, and educational barriers. These include a lack of a multidisciplinary team focused on AYA patients, mental health support, a dedicated space for this patient population, high treatment costs, travel distance to the hospital, and discontinuity of care due to age limits. In addition, there are competing demands for resources with adult oncology, delays in diagnosis, and patients' abandonment of treatment. Potential opportunities for improvement included having multidisciplinary AYA oncology teams, standardized treatment protocols, AYA-specific cancer registry, dedicated space, mental health support (e.g., support groups), improving access to health insurance, patient and physician education, and vocational assistance.</p><p><strong>Conclusions: </strong>This study identifies substantial barriers to the care of AYA patients with cancer in Central America, Mexico, the Caribbean, and Peru. It also highlights key areas for potential intervention to improve outcomes in this population. These key findings can guide cancer control programs in Latin America as they begin to include AYAs.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"358-367"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Corrigendum to:</i> Air Pollution and Cardiovascular Risks in Testicular Cancer Survivors: An Exploratory Case-Crossover Study.","authors":"","doi":"10.1177/21565333251365620","DOIUrl":"10.1177/21565333251365620","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"389"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Processes in Adolescents Receiving Palliative Oncology Care: Clinical Implications for Multidisciplinary Teams.","authors":"Giulia Zucchetti, Mario Giordano, Beatrice Giustetto, Francesca Rossi, Pierpaolo Chialvo, Daniele Bertin, Stefano Vallero, Paola Quarello, Franca Fagioli","doi":"10.1177/21565333261485756","DOIUrl":"https://doi.org/10.1177/21565333261485756","url":null,"abstract":"<p><strong>Purpose: </strong>Palliative care for adolescents with poor-prognosis cancer raises distinct and unresolved psychological challenges that differ from the broader adolescent and young adult (AYA) oncology population. This article aims to clarify key psychological processes of adolescents in palliative care and to support multidisciplinary teams in navigating complex behaviors and clinical decision-making.</p><p><strong>Approach: </strong>The study was grounded in developmental and psychodynamic theory and employed a structured reflective methodology to examine emotional, behavioral, and relational dynamics emerging during clinical management. Clinical observations and practices were integrated with current literature on palliative AYA oncology care.</p><p><strong>Conceptual framework: </strong>Anticipatory grief (AG) emerges as the primary psychological construct through which adolescents' experiences in palliative oncology care can be understood. It is associated with fragmentation of future perspectives, identity development, and bodily experiences. These processes are illustrated through clinical manifestations, with clear implications for multidisciplinary team practice. Defense mechanisms, along with transference and countertransference dynamics, are also crucial aspects for professionals to recognize and manage. Understanding these elements allows the health care team to provide better emotional containment, navigate relational complexities, and support the adolescent's evolving needs.</p><p><strong>Conclusions: </strong>Adolescents in palliative oncology require a distinct psychological framework that goes beyond standard AYA care models. Addressing AG as an organizing process of the adolescent experience calls for greater clinical attention to developmental disruption, relational dynamics, and meaning-making processes. Multidisciplinary teams should integrate reflective and psychologically informed approaches into routine care to improve care quality and clinical decision-making.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261485756"},"PeriodicalIF":1.6,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Outcomes of Melanoma Among Latin American Adolescents and Young Adults Compared to Middle-Aged and Elderly Population: A Cohort Analysis Over 10 Years.","authors":"Gabriel De la Cruz Ku, Anshumi Desai, Luis Piedra Delgado, Michael Mallouh, Carlos Gonzales, Jiddu Guart, Kabir Torres, Camila Franco, Marcelo Chavez Diaz, Gonzalo Ziegler","doi":"10.1177/21565333261485759","DOIUrl":"https://doi.org/10.1177/21565333261485759","url":null,"abstract":"<p><strong>Introduction: </strong>Outcomes among the Hispanic population are rarely explored in adolescents and young adults (AYAs). We aimed to compare sociodemographic, clinical, and survival outcomes of Latin American AYAs (≤39 years) with middle-aged (40-59 years) and older (≥60 years) patients with melanoma.</p><p><strong>Methods: </strong>A single-center retrospective cohort study among patients with melanoma stages I-IV was conducted in Lima, Peru, from 2010 to 2019. We evaluated overall survival (OS), event-free survival (EFS) rates, and prognostic factors.</p><p><strong>Results: </strong>Of 1121 patients with melanoma, 118 (10.5%) were AYAs, 357 (31.9%) were middle-aged, and 645 (57.6%) were elderly. Less frequencies of lower extremity as primary site (56.8%, 68.9%, and 82.3%, <i>p</i> < 0.01), ulceration (46.8%, 58.8%, 72.5%, <i>p</i> < 0.01), and acral histology (22.6%, and 32.8%, and 44.3%, <i>p</i> < 0.01) were present in AYAs. Moreover, AYAs had a higher frequency of American Joint Committee on Cancer stages I (16.1%, 10.1%, and 7.9%) and IV (25.4%, 24.6%, and 21.9%, <i>p</i> < 0.01). AYAs had less frequent adjuvant chemotherapy (10.3%, 18.4%, and 11.2%, <i>p</i> = 0.03). With a median follow-up of 9.8 years, the 5-year OS and EFS rates for AYAs (52%, 32%) were better than the middle-aged (43%, 23%) and older population (32%, 15%) (<i>p</i> < 0.01). Multivariate analyses showed that AYAs had better prognosis than elderly population (≥60 years, hazard ratio = 1.93).</p><p><strong>Conclusions: </strong>Latin American AYAs with melanoma had less aggressive tumor characteristics and received less systemic therapy compared to middle-aged patients, yet demonstrated better EFS and OS rates across all age groups. Therefore, younger age is not a risk factor for worse survival outcomes. Given the relatively high frequency of stage IV disease in AYAs, it is crucial to develop strategies for early detection in the primary care setting.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261485759"},"PeriodicalIF":1.6,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication Challenges and Strategies in Adolescent and Young Adult Cancer Survivorship Care: A Qualitative Study of Clinician Perspectives.","authors":"Mary Anne Kochenderfer, Briana Martin-Villa, Lidia Schapira, Stephanie M Smith","doi":"10.1177/21565333261483393","DOIUrl":"https://doi.org/10.1177/21565333261483393","url":null,"abstract":"<p><strong>Purpose: </strong>Adolescent and young adult (AYA) cancer survivors treated in pediatric settings face long-term physical and psychosocial effects from cancer treatment, and lifelong specialized survivorship care is recommended. Prior research has focused on <i>what</i> survivors need to know about past cancer and future health, with less emphasis on <i>how</i> clinicians communicate with AYAs and families. This study evaluated effective communication strategies and challenges with survivorship-related communication according to experienced clinicians.</p><p><strong>Methods: </strong>We conducted individual interviews with survivorship clinicians from diverse practice settings across the United States between November 2024 and February 2025. Interviews queried communication strategies, barriers, and recommendations for improving clinical interactions with AYA survivors. Qualitative analysis identified key themes and patterns.</p><p><strong>Results: </strong>Clinicians (nine females and three males), in practice for 4-37 years, were physicians specializing in pediatric oncology (<i>N</i> = 7; two with med-peds training), primary care with a survivorship focus (<i>N</i> = 3), or nurse practitioners (<i>N</i> = 2). Barriers to effective communication included information complexity and volume, lack of time, and anxiety among AYA survivors and families. Effective communication strategies included building rapport, a mindset to \"meet the patient where they're at,\" use of clear, accessible language with visual aids, and contextualizing information about health risks and associated uncertainty. Findings illustrated ways that clinician communication may promote or inhibit AYA engagement in survivorship care.</p><p><strong>Conclusion: </strong>Effective communication between clinicians and AYA cancer survivors may improve health outcomes by helping survivors understand health risks, managing associated uncertainty and anxiety, and promoting AYA engagement in survivorship care. This study will inform the development of communication interventions and training for clinicians.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261483393"},"PeriodicalIF":1.6,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ho'oulu Me Ke Ikaika: A Community-Support Group that Improves Long-Term Emotional and Social Health of Adolescent and Young Adult Survivors of Childhood Cancer.","authors":"Maile Enos, Kiyomi Goto, Joyce Wong, Patricia W Nishimoto, Erin O Bantum, Ian Pagano, Dianne Fochtman, Paulette M Yamada","doi":"10.1177/21565333261484109","DOIUrl":"https://doi.org/10.1177/21565333261484109","url":null,"abstract":"<p><strong>Purpose: </strong>Survivors of childhood cancer have unique needs, requiring tailored psychosocial support. To ascertain the effectiveness of a community-based survivorship group's services on changes in emotional and social self-efficacy, perceived purpose and meaning in life, loneliness, and post-traumatic growth from pre- to postretreat among minority adolescent and young adult (AYA) survivors over a 2-year period.</p><p><strong>Methods: </strong>Two annual residential retreats were attended by 15 and 13 AYA survivors, respectively. Experiential learning activities that fostered connection, self-reflection, and resilience were provided. Inventories assessing meaning/purpose (Patient-Reported Outcomes Measures Information Systems [PROMIS]), social (SSE) and emotional self-efficacy (ESE), loneliness, and Post-Traumatic Growth Inventory (PTGI) were administered at four timepoints (pre-/post-2024 and 2025 retreat). Quantitative data were analyzed with orthogonal polynomial contrasts and the MIXED procedure method. Qualitative survivor feedback was collected after the retreats. Counselor journals, participant quotes, and exit interviews were used to contextualize survivor-reported data.</p><p><strong>Results: </strong>PROMIS, SSE, and ESE improved immediately following the retreats, with continual improvement after the second retreat. PTGI did not change. After each retreat, AYAs scored the improvement in loneliness (7.3 ± 1.3 and 7.5 ± 1.9, respectively, with 10 representing maximal benefit), indicating that each retreat impacted their loneliness to the same degree. Qualitative data indicate that AYAs appreciated the opportunity to face difficult topics in a safe space and could benefit from attending consecutive retreats.</p><p><strong>Conclusion: </strong>The intervention benefited participants who were in different stages of their cancer and life journey and reached an underserved minority population. Implementation of these types of support groups could reduce loneliness and improve self-efficacy, thereby having broader impacts on quality of life.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261484109"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caring for Young Adults with Breast Cancer: Providers' Perspectives on Burnout in a Complex Care Landscape.","authors":"Caroline Lommer, Lila Schroeder, Caroline Amato, Katie Kenny, Lindsey Sova, Ann Scheck McAlearney, Tari A King, Ashley P Davenport, Sara P Myers","doi":"10.1177/21565333261481965","DOIUrl":"https://doi.org/10.1177/21565333261481965","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;While challenges faced by young adults (YAs) aged 18-39 years with breast cancer are well-documented, health care providers' experiences caring for YAs are underinvestigated. Given high burnout rates among oncologists, this study explores providers' perspectives about how complex care of YAs may impact emotional well-being.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Participants and methods: &lt;/strong&gt;A multidisciplinary cohort of breast oncology practitioners from a single Comprehensive Cancer Center were recruited to complete (1) semistructured interviews, and (2) the Maslach Burnout Inventory-Human Services Survey (MBI-HSS) between August and November 2025. Interview questions prompted participants' narratives about how complexities in clinical care for YAs might affect their emotional well-being. Transcribed interview audio-recordings were analyzed for recurring themes. Three MBI-HSS subscales were scored as follows: emotional exhaustion (low ≤ 16, moderate/high ≥ 17), depersonalization (low ≤ 5, moderate/high ≥ 6), and reduced personal accomplishment (low ≥ 40, moderate/high ≤ 39).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Participants included a multidisciplinary cohort of breast oncology providers comprised of 14 (70%) physicians and 6 (30%) advanced practice providers. Thirteen completed the MBI-HSS; 5 (38%) scored as moderate/high risk for emotional exhaustion and depersonalization, and 8 (62%) scored as moderate/high risk for reduced sense of professional achievement. Participant narratives highlighted four themes: (1) age-related considerations complicate care and contribute to workplace stress; (2) systematic barriers to patient care impact burnout; (3) multidisciplinary collaborations promote optimal care and provider well-being; and (4) system-level initiatives could facilitate delivery of high-value care.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;In this mixed-methods study of breast oncology providers caring for YA patients, risks for emotional exhaustion, depersonalization, and reduced sense of accomplishment were common. Qualitative findings underscore the emotional complexity of caring for this population and suggest that multidisciplinary support may play a crucial role in mitigating risk for burnout.Context Summary:Health care providers' experiences caring for young adults (YAs) aged 18-39 years with breast cancer are underinvestigated. Given high burnout rates among oncologists, this mixed-methods study explores providers' perspectives about how complex care of YAs may impact emotional well-being through (1) semistructured interviews, and (2) the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Of the 20 multidisciplinary breast oncology specialists who participated, 13 completed the MBI-HSS; 5 (38%) scored as moderate/high risk for emotional exhaustion and depersonalization, and 8 (62%) scored as moderate/high risk for reduced sense of professional achievement. Participant narratives highlighted four themes: (1) age-related conside","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261481965"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life of Adolescents and Young Adults with Cancer at Gustave Roussy Institute: The Role of Management in Enhancing Care and Ensuring Performance.","authors":"Morgane Cousin, Nathalie Sanquirgo, Lucy Metayer, Miguel Maiz, Benjamin Verret, Nathalie Gaspar","doi":"10.1177/21565333261483392","DOIUrl":"https://doi.org/10.1177/21565333261483392","url":null,"abstract":"<p><p>The Gustave Roussy Institute (IGR) is considered the leading cancer center in Europe. Since 2012, a multidisciplinary team dedicated to adolescents and young adults (AYAs)-known as SPIAJA-has been developing a comprehensive care model for patients in this age group treated at the IGR. This mobile unit, integrated into the pediatrics department, collaborates with several adult care departments and offers a wide range of specialized services. Based on both interviews and observations, this qualitative study highlights the role of leadership as a catalyst for overcoming barriers and improving interprofessional collaboration, which appears to have a positive impact on the quality of life of AYA patients. However, the identified barriers and challenges highlight certain performance limitations when this \"managerial culture\" is not implemented at all levels of the institution.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261483392"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Corrigendum to:</i> The Development of Parent Support Group Program in Young Adult Cancer Care.","authors":"","doi":"10.1177/21565333261486700","DOIUrl":"https://doi.org/10.1177/21565333261486700","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":"21565333261486700"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}