JACC. Cardiovascular interventions最新文献

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Left Main Spontaneous Coronary Artery Dissection 左主干自发性冠状动脉夹层
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2025.03.003
Fernando Alfonso MD, David del Val MD, Teresa Bastante MD
{"title":"Left Main Spontaneous Coronary Artery Dissection","authors":"Fernando Alfonso MD, David del Val MD, Teresa Bastante MD","doi":"10.1016/j.jcin.2025.03.003","DOIUrl":"10.1016/j.jcin.2025.03.003","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 984-987"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter Pulmonary Valve Implantation Using Self-Expandable Percutaneous Pulmonary Valve System 使用自膨胀的经皮肺动脉瓣系统经导管肺动脉瓣植入术:3年的CE研究结果。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2024.12.031
Shakeel A. Qureshi MD , Matthew I. Jones MD , Kuberan Pushparajah MD , Jou-Kou Wang MD , Damien Kenny MD , Kevin Walsh MD , Younes Boudjemline MD , Worakan Promphan MD , Pimpak Prachasilchai MD , John Thomson MD , James R. Bentham MD , Felix Berger MD , Carlos A.C. Pedra MD , Marc Gewillig MD , Bryan P. Yan MD , Ziyad M. Hijazi MD
{"title":"Transcatheter Pulmonary Valve Implantation Using Self-Expandable Percutaneous Pulmonary Valve System","authors":"Shakeel A. Qureshi MD ,&nbsp;Matthew I. Jones MD ,&nbsp;Kuberan Pushparajah MD ,&nbsp;Jou-Kou Wang MD ,&nbsp;Damien Kenny MD ,&nbsp;Kevin Walsh MD ,&nbsp;Younes Boudjemline MD ,&nbsp;Worakan Promphan MD ,&nbsp;Pimpak Prachasilchai MD ,&nbsp;John Thomson MD ,&nbsp;James R. Bentham MD ,&nbsp;Felix Berger MD ,&nbsp;Carlos A.C. Pedra MD ,&nbsp;Marc Gewillig MD ,&nbsp;Bryan P. Yan MD ,&nbsp;Ziyad M. Hijazi MD","doi":"10.1016/j.jcin.2024.12.031","DOIUrl":"10.1016/j.jcin.2024.12.031","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary regurgitation is common during follow-up of patients after surgical repair of tetralogy of Fallot and other right ventricular outflow tracts (RVOTs). Many percutaneous pulmonary valves have been used but are limited to smaller RVOTs.</div></div><div><h3>Objectives</h3><div>Since August 2016, a multicenter CE (Conformité Européenne) study was initiated to evaluate a self-expandable VenusP-valve. We aimed to report the acute and 3-year follow-up results.</div></div><div><h3>Methods</h3><div>A total of 81 patients with pulmonary regurgitation were recruited for VenusP-valve implantation and assessed for a 3-year period.</div></div><div><h3>Results</h3><div>In all patients, VenusP-valves were successfully implanted. The mean age was 26.5 ± 13.3 years and the mean weight 59.5 ± 15.6 kg. There was no early procedure-related or late mortality. One patient experienced guidewire perforation of a branch pulmonary artery, causing hemoptysis, and 1 had ventricular tachycardia, at the end of the procedure. During follow-up, 1 patient developed runs of ventricular tachycardia and needed an implantable cardioverter-defibrillator and ablation of the RVOT 5 months after valve implantation. One developed endocarditis 11 months after implantation. After medical treatment, the valve has continued to function normally. One patient developed thrombus on the distal flare 3 years after implantation and was treated with anticoagulants. During 3-year follow-up, valve function has remained satisfactory and right ventricular remodeling has occurred in all patients.</div></div><div><h3>Conclusions</h3><div>We report the 3-year CE study results of percutaneous pulmonary valve implantation in patients with severe pulmonary regurgitation. The valve has shown promising safety and durability. Long-term evaluation is warranted.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1045-1056"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter Pulmonary Valves for the Native RVOT 经导管肺瓣膜治疗原生RVOT:金星是否上升?
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2024.11.046
Matthew J. Daniels MD, PhD , Santiago Garcia MD
{"title":"Transcatheter Pulmonary Valves for the Native RVOT","authors":"Matthew J. Daniels MD, PhD ,&nbsp;Santiago Garcia MD","doi":"10.1016/j.jcin.2024.11.046","DOIUrl":"10.1016/j.jcin.2024.11.046","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1057-1059"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Torn Leaflet 瓣叶撕裂:经导管主动脉瓣假体退行性手术的罕见并发症。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2024.11.024
Joaquín Vila-García MD, Guillermo De La Osa Hernández MD, Ángel Manuel Iniesta Manjavacas MD, Silvia Cayetana Valbuena López MD, Guillermo Galeote García MD, PhD, Elsa Prieto Moriche MD, Raúl Moreno MD, PhD
{"title":"A Torn Leaflet","authors":"Joaquín Vila-García MD,&nbsp;Guillermo De La Osa Hernández MD,&nbsp;Ángel Manuel Iniesta Manjavacas MD,&nbsp;Silvia Cayetana Valbuena López MD,&nbsp;Guillermo Galeote García MD, PhD,&nbsp;Elsa Prieto Moriche MD,&nbsp;Raúl Moreno MD, PhD","doi":"10.1016/j.jcin.2024.11.024","DOIUrl":"10.1016/j.jcin.2024.11.024","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1062-1064"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal Trends in 1-Year Cause-Specific Mortality After TAVR TAVR后1年病因特异性死亡率的时间趋势:来自STS/ACC TVT登记的见解
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2024.12.016
Dhaval Kolte MD, PhD, MPH , Guillaume Marquis-Gravel MD, MSc , Amanda Stebbins MS , Andrew M. Vekstein MD , Sreekanth Vemulapalli MD , Sammy Elmariah MD, MPH
{"title":"Temporal Trends in 1-Year Cause-Specific Mortality After TAVR","authors":"Dhaval Kolte MD, PhD, MPH ,&nbsp;Guillaume Marquis-Gravel MD, MSc ,&nbsp;Amanda Stebbins MS ,&nbsp;Andrew M. Vekstein MD ,&nbsp;Sreekanth Vemulapalli MD ,&nbsp;Sammy Elmariah MD, MPH","doi":"10.1016/j.jcin.2024.12.016","DOIUrl":"10.1016/j.jcin.2024.12.016","url":null,"abstract":"<div><h3>Background</h3><div>The impact of changing patient demographics and risk profiles on cause-specific mortality after transcatheter aortic valve replacement (TAVR) remains unclear.</div></div><div><h3>Objectives</h3><div>The aim of this study was to examine causes of death (CoDs) and temporal trends and predictors of cause-specific mortality after TAVR.</div></div><div><h3>Methods</h3><div>Data from the Society of Thoracic Surgeons/American College of Cardiology TVT (Transcatheter Valve Therapy) Registry were analyzed to identify patients who underwent isolated TAVR between January 2012 and October 2022 who had available information on 1-year CoD. The primary outcome was cause-specific (cardiac and noncardiac) mortality at 1 year. Fine and Gray subdistribution hazard models were used to account for the competing risk for cause-specific death.</div></div><div><h3>Results</h3><div>Of 36,877 patients who died within 1 year after TAVR and had available information on CoD, 11,560 (31.3%) had cardiac death and 25,317 (68.7%) had noncardiac death. There was an initial decline in the risk-adjusted hazards of 1-year cardiac and noncardiac death after TAVR from 2012 to 2017 (adjusted HR per year: 0.95 [95% CI: 0.92-0.97] and 0.92 [95% CI: 0.90-0.93], respectively), followed by an increase from 2018 to 2022 (adjusted HR per year: 1.07 [95% CI: 1.05-1.09] and 1.22 [95% CI: 1.20-1.24], respectively). Age &gt;80 years, comorbidities, poor functional status, nonelective procedure, nonfemoral access, and in-hospital complications were identified as independent predictors of both cardiac and noncardiac death after TAVR.</div></div><div><h3>Conclusions</h3><div>Noncardiac causes account for two-thirds of deaths within 1 year after TAVR. Further studies are needed to examine whether the COVID-19 pandemic, the rapid expansion in the number of TAVR sites, or other patient and hospital characteristics contributed to the increased risk for cardiac and noncardiac death after TAVR in recent years.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1013-1024"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Articulating the JACC Journals’ Direction in Times of Global Change 论全球变化时代JACC期刊的发展方向
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2025.02.001
Harlan M. Krumholz MD, SM (Editor-in-Chief, JACC), Biykem Bozkurt MD, PhD (Editor-in-Chief, JACC: Heart Failure), Y. Chandrashekhar MD (Editor-in-Chief, JACC: Cardiovascular Imaging), Bonnie Ky MD, MSCE (Editor-in-Chief, JACC: CardioOncology), Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science), David J. Moliterno MD (Editor-in-Chief, JACC: Cardiovascular Interventions), Kalyanam Shivkumar MD, PhD (Editor-in-Chief, JACC: Clinical Electrophysiology), Candice K. Silversides MD (Editor-in-Chief, JACC: Advances), Gilbert H.L. Tang MD, MSc, MBA (Editor-in-Chief, JACC: Case Reports), Jian’an Wang MD, PhD (Editor-in-Chief, JACC: Asia)
{"title":"Articulating the JACC Journals’ Direction in Times of Global Change","authors":"Harlan M. Krumholz MD, SM (Editor-in-Chief, JACC),&nbsp;Biykem Bozkurt MD, PhD (Editor-in-Chief, JACC: Heart Failure),&nbsp;Y. Chandrashekhar MD (Editor-in-Chief, JACC: Cardiovascular Imaging),&nbsp;Bonnie Ky MD, MSCE (Editor-in-Chief, JACC: CardioOncology),&nbsp;Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science),&nbsp;David J. Moliterno MD (Editor-in-Chief, JACC: Cardiovascular Interventions),&nbsp;Kalyanam Shivkumar MD, PhD (Editor-in-Chief, JACC: Clinical Electrophysiology),&nbsp;Candice K. Silversides MD (Editor-in-Chief, JACC: Advances),&nbsp;Gilbert H.L. Tang MD, MSc, MBA (Editor-in-Chief, JACC: Case Reports),&nbsp;Jian’an Wang MD, PhD (Editor-in-Chief, JACC: Asia)","doi":"10.1016/j.jcin.2025.02.001","DOIUrl":"10.1016/j.jcin.2025.02.001","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1087-1088"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel TAVR Device and Whole-Body Embolic Protection for Safe and Effective Bicuspid Aortic Valve Treatment 新型TAVR装置和全身栓塞保护安全有效地治疗二尖瓣主动脉瓣
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2025.02.012
Alessandro Sticchi MD , Dario Grassini MD , Giulia Costa MD , Paolo Spontoni MD , Marco Angelillis MD , Cristina Giannini MD , Marco De Carlo MD
{"title":"Novel TAVR Device and Whole-Body Embolic Protection for Safe and Effective Bicuspid Aortic Valve Treatment","authors":"Alessandro Sticchi MD ,&nbsp;Dario Grassini MD ,&nbsp;Giulia Costa MD ,&nbsp;Paolo Spontoni MD ,&nbsp;Marco Angelillis MD ,&nbsp;Cristina Giannini MD ,&nbsp;Marco De Carlo MD","doi":"10.1016/j.jcin.2025.02.012","DOIUrl":"10.1016/j.jcin.2025.02.012","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1072-1075"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial Dyscoaptation of SAPIEN 3 Ultra RESILIA Treated by Postballooning During Transcatheter Aortic Valve Replacement 经导管主动脉瓣置换术中球囊后栓塞治疗SAPIEN 3超弹性瓣膜部分失适应。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2025.01.448
Takahide Sano MD , Mike Saji MD, PhD , Kojiro Sakurai MD , Kota Kawada MD , Hideo Amano MD, PhD , Takeshiro Fujii MD, PhD
{"title":"Partial Dyscoaptation of SAPIEN 3 Ultra RESILIA Treated by Postballooning During Transcatheter Aortic Valve Replacement","authors":"Takahide Sano MD ,&nbsp;Mike Saji MD, PhD ,&nbsp;Kojiro Sakurai MD ,&nbsp;Kota Kawada MD ,&nbsp;Hideo Amano MD, PhD ,&nbsp;Takeshiro Fujii MD, PhD","doi":"10.1016/j.jcin.2025.01.448","DOIUrl":"10.1016/j.jcin.2025.01.448","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1070-1071"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transesophageal Echocardiography Guidance Is Useful for Valve-in-Valve Transcatheter Aortic Valve Replacement 经食管超声心动图指导对经导管主动脉瓣置换术有用。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2025.01.443
Lior Henri Fortis MD, MHA , Akshat Khurana MD , Yoav Niv Granot MD , Lori B. Croft MD , Amit Hooda MD , Sahil Khera MD, MPH , Francesca Romana Prandi MD , Gilbert H.L. Tang MD, MSc, MBA , Samin K. Sharma MD , Annapoorna Kini MD , Stamatios Lerakis MD, PhD
{"title":"Transesophageal Echocardiography Guidance Is Useful for Valve-in-Valve Transcatheter Aortic Valve Replacement","authors":"Lior Henri Fortis MD, MHA ,&nbsp;Akshat Khurana MD ,&nbsp;Yoav Niv Granot MD ,&nbsp;Lori B. Croft MD ,&nbsp;Amit Hooda MD ,&nbsp;Sahil Khera MD, MPH ,&nbsp;Francesca Romana Prandi MD ,&nbsp;Gilbert H.L. Tang MD, MSc, MBA ,&nbsp;Samin K. Sharma MD ,&nbsp;Annapoorna Kini MD ,&nbsp;Stamatios Lerakis MD, PhD","doi":"10.1016/j.jcin.2025.01.443","DOIUrl":"10.1016/j.jcin.2025.01.443","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1067-1069"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sirolimus- vs Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis 西罗莫司与紫杉醇包被球囊治疗冠状动脉支架内再狭窄:SIBLINT-ISR随机试验。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-04-28 DOI: 10.1016/j.jcin.2024.12.024
Haiwei Liu MD , Yi Li MD , Guosheng Fu MD , Jian An MD , Shaoliang Chen MD , Zhixiong Zhong MD , Bin Liu MD , Chunguang Qiu MD , Likun Ma MD , Hongliang Cong MD , Hui Li MD , Qian Tong MD , Ben He MD , Zening Jin MD , Jun Zhang MD , Haitao Yuan MD , Miaohan Qiu MD , Ruiyan Zhang MD , Yaling Han MD
{"title":"Sirolimus- vs Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis","authors":"Haiwei Liu MD ,&nbsp;Yi Li MD ,&nbsp;Guosheng Fu MD ,&nbsp;Jian An MD ,&nbsp;Shaoliang Chen MD ,&nbsp;Zhixiong Zhong MD ,&nbsp;Bin Liu MD ,&nbsp;Chunguang Qiu MD ,&nbsp;Likun Ma MD ,&nbsp;Hongliang Cong MD ,&nbsp;Hui Li MD ,&nbsp;Qian Tong MD ,&nbsp;Ben He MD ,&nbsp;Zening Jin MD ,&nbsp;Jun Zhang MD ,&nbsp;Haitao Yuan MD ,&nbsp;Miaohan Qiu MD ,&nbsp;Ruiyan Zhang MD ,&nbsp;Yaling Han MD","doi":"10.1016/j.jcin.2024.12.024","DOIUrl":"10.1016/j.jcin.2024.12.024","url":null,"abstract":"<div><h3>Background</h3><div>The use of drug-coated balloons is a well-established strategy for the management of coronary vessels. However, head-to-head comparisons of sirolimus-coated balloons (SCBs) and paclitaxel-coated balloons (PCBs) for treating in-stent restenosis (ISR) are currently limited.</div></div><div><h3>Objectives</h3><div>The aim of this randomized, controlled trial (SIBLINT-ISR [Sirolimus-Coated Balloon Versus Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis]) was to compare a novel SCB with a PCB for the treatment of ISR.</div></div><div><h3>Methods</h3><div>In this prospective, assessor-blinded, controlled trial, patients with eligible ISR lesions were randomized 1:1 to treatment with either an SCB (SeQuent SCB, B. Braun Melsungen; 4 μg/mm<sup>2</sup>) or a PCB (SeQuent Please NEO, B. Braun Melsungen; 3 μg/mm<sup>2</sup>). The primary endpoint was noninferiority for 9-month angiographic in-segment late lumen loss (LLL). The main secondary endpoints were procedural success, target lesion restenosis rate, and target lesion failure (cardiac death, target vessel myocardial infarction, or revascularization) at 12 months.</div></div><div><h3>Results</h3><div>A total of 258 patients with 285 lesions at 16 sites were randomly assigned to the SCB (n = 130) and PCB (n = 128) groups. At 9 months, the difference in the primary endpoint of in-segment LLL between the SCB group (0.37 ± 0.48 mm) and the PCB group (0.30 ± 0.38 mm) was 0.07 mm (95% CI: −0.05 to 0.19 mm), demonstrating noninferiority of the SCB to the PCB in terms of in-segment LLL, with a noninferiority margin of 0.20 mm (<em>P</em> for noninferiority &lt; 0.0001). There were no significant differences in 12-month clinical outcomes between the SCB and PCB groups.</div></div><div><h3>Conclusions</h3><div>In this study, a novel SCB was found to be noninferior to a PCB in terms of in-segment LLL at 9 months in treating patients with ISR. (Sirolimus-Coated Balloon Versus Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis [SIBLINT ISR]; <span><span>NCT04240444</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 963-971"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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