JAMA Pediatrics最新文献_第7页

Further Considerations on Corticosteroid Use in Premature Infants.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.7130

Floris Groenendaal

引用次数: 0

Is Low-Fat Dairy an Appropriate Recommendation for Children?

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.7105

Natalie Xiao-Wen Ng, Susan Michelle Gross

引用次数: 0

Further Considerations on Corticosteroid Use in Premature Infants.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.7127

Talkad S Raghuveer, R E Zackula

引用次数: 0

What Parents Need to Know About Knee Pain in Active Children.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.6164

Maria Isabel Angulo, Geisel R Collazo, Lindsay A Thompson

引用次数: 0

Further Considerations on Corticosteroid Use in Premature Infants-Reply.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.7124

Lex W Doyle, Rheanna M Mainzer, Jeanie L Y Cheong

引用次数: 0

Antimicrobial Prophylaxis Use and Outcomes for Children Undergoing Cholecystectomy.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-24 DOI: 10.1001/jamapediatrics.2024.6391

Kerri A McKie, Anoosha Moturu, Dionne A Graham, Melvin Coleman, Reiping Huang, Catherine Grant, Jacqueline M Saito, Bruce L Hall, Robert A Cina, Jason G Newland, Clifford Ko, Shawn J Rangel

{"title":"Antimicrobial Prophylaxis Use and Outcomes for Children Undergoing Cholecystectomy.","authors":"Kerri A McKie, Anoosha Moturu, Dionne A Graham, Melvin Coleman, Reiping Huang, Catherine Grant, Jacqueline M Saito, Bruce L Hall, Robert A Cina, Jason G Newland, Clifford Ko, Shawn J Rangel","doi":"10.1001/jamapediatrics.2024.6391","DOIUrl":"10.1001/jamapediatrics.2024.6391","url":null,"abstract":"Importance: Consensus guidelines from the Infectious Disease Society of America recommend against antimicrobial prophylaxis in the operative management of uncomplicated cholelithiasis; however, these guidelines were derived entirely from the adult surgical population.Objective: To compare surgical site infection (SSI) outcomes between children undergoing cholecystectomy who received prophylaxis and those who did not.Design, setting, and participants: This was a cohort study using data from 141 hospitals participating in the National Surgical Quality Improvement Program-Pediatric. Patients younger than 18 years who underwent cholecystectomy for uncomplicated cholelithiasis from January 2021 to December 2022 were identified. Exclusion criteria included diagnoses of acute cholecystitis, pancreatitis, choledocholithiasis, hematologic disorders, and emergent procedures.Exposure: Administration of prophylactic antibiotics before incision.Main outcomes and measures: The main outcomes were 30-day postoperative SSI and readmission. Propensity score weighting on the likelihood of receiving prophylaxis was used to balance groups on case acuity, duration of surgery, hospital discharge diagnosis, and patient characteristics. The association between outcomes and the use of prophylaxis was estimated using logistic regression models, weighted by the inverse probability of treatment with a random effect by hospital to control for hospital-level clustering. A secondary analysis was performed exploring the association between broad-spectrum prophylaxis and outcomes.Results: Of 2234 children who met criteria for inclusion (median age, 15.3 years; 19.7% male [399 of 2025]), 2025 (90.6%) received prophylaxis (utilization rates ranged from 0% to 100% among hospitals). Cefazolin was the most commonly used antibiotic (69.2% [1401 of 2025]), and 559 of 2025 patients (27.6%) received extended-spectrum prophylaxis (compared with cefazolin). In the propensity-weighted cohort, SSI rates were lower for children who received prophylaxis compared with those who did not (18.0 of 2016 [0.9%] vs 7.8 of 212 [3.7%]; adjusted odds ratio [AOR], 0.28; 95% CI, 0.11-0.70), and rates were similar between children receiving cefazolin and those receiving more extended-spectrum antibiotics in a secondary propensity-weighted analysis (13.9 of 1399 [1.0%] vs 2.9 of 558 [0.5%]; AOR, 0.54; 95% CI, 0.15-1.95).Conclusions and relevance: The results of this study support prophylaxis use for children undergoing nonemergent cholecystectomy; however, use of extended-spectrum antibiotics was not associated with superior outcomes compared with cefazolin alone. Opportunities to optimize infection prevention or antimicrobial stewardship were identified in more than one-third of all children undergoing cholecystectomy.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supplemental Security Income for Low-Birth-Weight Infants-Addressing Gaps in Coverage.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-17 DOI: 10.1001/jamapediatrics.2024.6268

Erika Gabriela Cordova-Ramos, Emily Miller, Susanne Klawetter

引用次数: 0

Receipt of Federal Income Support by Eligible Low-Birth-Weight Infants

IF 26.1 1区医学

JAMA Pediatrics Pub Date : 2025-02-17 DOI: 10.1001/jamapediatrics.2024.6262

Muqi Guo, Michelle Woodford Martin, Nolan M. Kavanagh, Jarvis T. Chen, Jeffrey Hemmeter, Ichiro Kawachi, Margaret Parker, Margaret McConnell

{"title":"Receipt of Federal Income Support by Eligible Low-Birth-Weight Infants","authors":"Muqi Guo, Michelle Woodford Martin, Nolan M. Kavanagh, Jarvis T. Chen, Jeffrey Hemmeter, Ichiro Kawachi, Margaret Parker, Margaret McConnell","doi":"10.1001/jamapediatrics.2024.6262","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2024.6262","url":null,"abstract":"ImportanceWhile many infants with low birth weight (LBW) are eligible for Supplemental Security Income (SSI), more evidence is needed about whether they receive benefits and whether income supports reach infants from the most socioeconomically disadvantaged households.ObjectiveTo assess receipt of SSI among LBW-eligible infants (infants eligible due to LBW) and targeting of SSI to LBW and income-eligible infants across county-level measures of socioeconomic disadvantage.Design, Setting, and ParticipantsThis cross-sectional study used administrative data from the SSI program, vital records, and the American Community Survey. It included a population-based sample of 185 920 LBW infants born between January 1, 2012, and December 31, 2018, from 482 US counties, with 2003 revised birth certificates, Social Security Administration–defined LBW, and survival of more than 31 days, and born in a county-year with at least 20 LBW infants surviving their first month of life. Analyses were conducted from January 1, 2022, to December 31, 2023.ExposuresThree measures of county-level socioeconomic disadvantage: poverty rates, median household income, and completion of postsecondary degrees.Main Outcomes and MeasuresReceipt of SSI among (1) infants who qualified due to LBW and (2) LBW- and likely income-eligible infants. In addition, whether receipt varied by county-level measures of socioeconomic disadvantage was evaluated using Poisson regression models.ResultsA total of 185 920 LBW-eligible infants were included in the study. During the study period, the proportion of LBW-eligible infants who received SSI was 0.38 (95% CI, 0.36-0.40). SSI receipt was higher in more disadvantaged counties measured by county poverty rates or median household income. After adjusting income eligibility, the proportion receiving SSI reached 0.65 (95% CI, 0.49-0.86). However, SSI receipt among LBW- and likely income-eligible infants decreased as the level of county socioeconomic disadvantage increased.Conclusions and RelevanceIn this cross-sectional study, most LBW infants who were eligible for SSI did not receive benefits. Likely income-eligible infants living in socioeconomically disadvantaged counties were covered by SSI at lower levels than those in more advantaged counties. More intensive outreach or reduced application burden may be necessary to ensure equitable access to social safety net programs in socioeconomically disadvantaged communities.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"36 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental and Somatic Conditions in Children With the Broad Avoidant Restrictive Food Intake Disorder Phenotype

IF 26.1 1区医学

JAMA Pediatrics Pub Date : 2025-02-17 DOI: 10.1001/jamapediatrics.2024.6065

Marie-Louis Wronski, Ralf Kuja-Halkola, Elin Hedlund, Miriam I. Martini, Paul Lichtenstein, Sebastian Lundström, Henrik Larsson, Mark J. Taylor, Nadia Micali, Cynthia M. Bulik, Lisa Dinkler

{"title":"Mental and Somatic Conditions in Children With the Broad Avoidant Restrictive Food Intake Disorder Phenotype","authors":"Marie-Louis Wronski, Ralf Kuja-Halkola, Elin Hedlund, Miriam I. Martini, Paul Lichtenstein, Sebastian Lundström, Henrik Larsson, Mark J. Taylor, Nadia Micali, Cynthia M. Bulik, Lisa Dinkler","doi":"10.1001/jamapediatrics.2024.6065","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2024.6065","url":null,"abstract":"ImportanceAvoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by limited variety and/or quantity of food intake impacting physical health and psychosocial functioning. Children with ARFID often present with diverse psychiatric and somatic symptoms and therefore consult various pediatric subspecialties. Large-scale studies mapping coexisting conditions are, however, lacking.ObjectiveTo characterize the health care needs of youth with ARFID.Design, Setting, and ParticipantsThis cohort study used the Child and Adolescent Twin Study in Sweden (CATSS), in combination with inpatient and specialized outpatient clinical diagnoses from the Swedish National Patient Register. Data were collected from July 2004 to April 2020, and data were analyzed from September 2022 to February 2024.ExposureUsing a composite measure derived from parent or guardian reports and register data, children with the broad ARFID phenotype occurring between the ages of 6 to 12 years were identified, as well as children without ARFID.Main Outcomes and MeasuresFrom more than 1000 diagnostic <jats:italic>International Classification of Diseases </jats:italic>(<jats:italic>ICD</jats:italic>) codes, mental and somatic conditions within or across <jats:italic>ICD</jats:italic> chapters, the number of distinct per-person diagnoses, and inpatient treatment days between participants’ birth and 18th birthdays were specified (90 outcomes). Hazard ratios (HRs) and incidence rate ratios (IRRs) were calculated.ResultsOf 30 795 CATSS participants, a total of 616 children (2.0%) with the broad ARFID phenotype occurring between the ages of 6 to 12 years were identified, and 30 179 children without ARFID were identified. Of 616 children with ARFID, 241 children were female (39.1%). Relative risks of neurodevelopmental, gastrointestinal, endocrine or metabolic, respiratory, neurological, and allergic disorders were substantially increased in children with ARFID (eg, autism: HR, 9.7; 95% CI, 7.5-12.5; intellectual disability: HR, 10.3; 95% CI, 7.6-13.9; gastroesophageal reflux disease: HR, 6.7; 95% CI, 4.6-9.9; pituitary conditions: HR, 5.6; 95% CI, 2.7-11.3; chronic lower respiratory diseases: HR, 4.9; 95% CI, 2.4-10.1; and epilepsy: HR, 5.8; 95% CI, 4.1-8.2). ARFID was not associated with elevated risks of autoimmune illnesses and obsessive-compulsive disorder. Children with ARFID had significantly more distinct mental diagnoses (IRR, 4.7; 95% CI, 4.0-5.4) and longer hospital stays (IRR, 5.5; 95% CI, 1.7-17.6) compared with children without ARFID. Children with ARFID were diagnosed with a mental condition earlier than children without ARFID. No sex-specific differences emerged.Conclusions and RelevanceThis cohort study yields the broadest and most detailed evidence of coexisting mental and somatic conditions in the largest sample of children with ARFID to date. Findings suggest a complex pattern of health needs in youth with ARFID, underscoring the critica","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"5 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NICHD Magnetic Resonance Brain Imaging Score in Term Infants With Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of a Randomized Clinical Trial.

IF 24.7 1区医学

JAMA Pediatrics Pub Date : 2025-02-17 DOI: 10.1001/jamapediatrics.2024.6209

Seetha Shankaran, Abbot R Laptook, Carolina Guimaraes, Johnathan Murnick, Scott A McDonald, Abhik Das, Carolyn M Petrie Huitema, Athina Pappas, Rosemary D Higgins, Susan R Hintz, Kristin M Zaterka-Baxter, Krisa P Van Meurs, Gregory M Sokol, Lina F Chalak, Tarah T Colaizy, Uday Devaskar, Jon E Tyson, Anne Marie Reynolds, Sara B DeMauro, Pablo J Sánchez, Matthew M Laughon, Waldemar A Carlo, Kristi Watterberg, Karen M Puopolo, Anna Maria Hibbs, Shannon E G Hamrick, C Michael Cotten, John Barks, Brenda B Poindexter, William E Truog, Carl T D'Angio

{"title":"NICHD Magnetic Resonance Brain Imaging Score in Term Infants With Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of a Randomized Clinical Trial.","authors":"Seetha Shankaran, Abbot R Laptook, Carolina Guimaraes, Johnathan Murnick, Scott A McDonald, Abhik Das, Carolyn M Petrie Huitema, Athina Pappas, Rosemary D Higgins, Susan R Hintz, Kristin M Zaterka-Baxter, Krisa P Van Meurs, Gregory M Sokol, Lina F Chalak, Tarah T Colaizy, Uday Devaskar, Jon E Tyson, Anne Marie Reynolds, Sara B DeMauro, Pablo J Sánchez, Matthew M Laughon, Waldemar A Carlo, Kristi Watterberg, Karen M Puopolo, Anna Maria Hibbs, Shannon E G Hamrick, C Michael Cotten, John Barks, Brenda B Poindexter, William E Truog, Carl T D'Angio","doi":"10.1001/jamapediatrics.2024.6209","DOIUrl":"10.1001/jamapediatrics.2024.6209","url":null,"abstract":"Importance: The neonatal brain injury score on magnetic resonance imaging following moderate or severe hypoxic-ischemic encephalopathy developed by the National Institute of Child Health and Human Development Neonatal Research Network has been revised to separate watershed and basal ganglia or thalamic injury and their associated outcomes.Objective: To evaluate the association of the injury score with outcomes of death or moderate or severe disability among all infants, and with neurodevelopment among survivors in a trial of deeper and longer cooling.Design, setting, and participants: In this secondary analysis of a multicenter randomized clinical trial, brain imaging was obtained from infants between October 2010 and November 2013. Infants were followed up to 18 months of age, with follow-up completed in January 2016. Data analysis was performed from August 2021 to September 2024.Interventions: Infants were assigned to 4 hypothermia groups based on depth and duration of cooling, stratified by center and level of encephalopathy in a 2 × 2 factorial design to cooling at 33.5 °C or 32.0 °C and to 72 or 120 hours. A 10-level brain injury score was examined.Main outcomes and measures: The primary outcome was death or moderate or severe disability measured by the Bayley Scales of Infant and Toddler Development III, the Gross Motor Function Classification System level, vision, and hearing.Results: This study included 298 infants who had magnetic resonance imaging (MRI) and primary outcome data among 364 infants of the initial cohort (mean [SD] age at MRI, 9.18 [4.49] days). Death or moderate or severe disability occurred in 72 of 298 infants (24%), and disability occurred in 52 of 278 surviving infants (19%). Death or disability occurred in 12 of 28 infants (43%) with any or predominant watershed injury and in 17 of 46 (37%) of those with any or predominant basal ganglia or thalamic injury. Among the 32 infants with hemispheric devastation, 30 (94%) had death or disability, and 17 (89%) survived with moderate or severe disability. Injury scores of increasing severity were associated with death or disability among all infants (odds ratio, 13.66 [95% CI, 7.47-24.95]; area under the curve, 0.84 [95% CI, 0.78-0.90]) and with disability among surviving infants (odds ratio, 10.52 [95% CI, 5.46-20.28]; area under the curve, 0.80 [95% CI, 0.73-0.88]). There were no differences in the injury score between infants undergoing usual care cooling and those cooled to a greater depth or longer duration.Conclusions: Among infants with hypoxic-ischemic encephalopathy, outcomes were similar between infants with watershed and basal ganglia injury. Higher imaging scores were associated with risk of death or disability among all infants and with neurodevelopmental disability among surviving infants.<stron","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0