JAMA Pediatrics最新文献

{"title":"Implications of Abortion Restrictions for Adolescents","authors":"Laura D. Lindberg, Julie Maslowsky, Paz Baum","doi":"10.1001/jamapediatrics.2025.0226","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0226","url":null,"abstract":"This cross-sectional study examines the proportion of the adolescent population potentially facing barriers to abortion access owing to 3 types of state restrictions in the US.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"102 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antenatal Opioid Exposure and Global and Regional Brain Volumes in Newborns","authors":"Yao Wu, Stephanie L. Merhar, Carla M. Bann, Jamie E. Newman, Kushal Kapse, Josepheen De Asis-Cruz, Nicole Mack, Sara B. De Mauro, Namasivayam Ambalavanan, Jonathan M. Davis, Scott A. Lorch, Deanne Wilson-Costello, Brenda B. Poindexter, Myriam Peralta-Carcelen, Catherine Limperopoulos","doi":"10.1001/jamapediatrics.2025.0277","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0277","url":null,"abstract":"ImportanceAlthough antenatal opioid exposure is associated with impaired brain growth, previous studies are limited by small sample sizes and lack of controls. As a result, the impacts of opioid exposure on the developing brain remain poorly understood.ObjectiveTo compare global, regional, and tissue-specific brain volumes in opioid-exposed newborns vs unexposed controls.Design, Setting, and ParticipantsIn the OBOE (Outcomes of Babies with Opioid Exposure) study, term newborns with antenatal opioid exposure and unexposed controls were recruited at 4 sites in the US from August 2020 to December 2023. Data analysis was performed from August 2020 to December 2024.Main Outcomes and MeasuresThe primary outcome was brain volumes in both groups, assessed via unsedated 3-dimensional (3-D) volumetric magnetic resonance imaging (MRI) in opioid-exposed and unexposed newborns prior to 8 weeks of age. T2-weighted MRI data were acquired on Siemens and Philips 3T scanners and harmonized across sites. Brains were segmented using DrawEM- and 3D U-Net–based pipelines and manual corrections. Brain volumes were compared between groups using analysis of covariance, adjusting for postmenstrual age at MRI, sex, birth weight, maternal smoking, and maternal education.ResultsA total of 173 newborns with antenatal opioid exposure and 96 unexposed controls were studied. MRIs were performed at a mean (SD) age of 42.84 (2.11) postmenstrual weeks, and 117 newborns (43.5%) were female. The opioid-exposed group had significantly smaller total brain volume (387.51 vs 407.06 cm<jats:sup>3</jats:sup>; difference, 19.55; 95% CI, 8.75-30.35) and cortical (167.07 vs 176.35 cm<jats:sup>3</jats:sup>; difference, 9.28; 95% CI, 3.86-14.70), deep gray matter (27.22 vs 28.76 cm<jats:sup>3</jats:sup>; difference, 1.54; 95% CI, 0.66-2.43), white matter (159.90 vs 166.65 cm<jats:sup>3</jats:sup>; difference, 6.76; 95% CI, 1.71-11.81), cerebellar (23.47 vs 24.99 cm<jats:sup>3</jats:sup>; difference, 1.52; 95% CI, 0.67-2.36), brainstem (6.80 vs 7.18 cm<jats:sup>3</jats:sup>; difference, 0.38; 95% CI, 0.19-0.57), and amygdala volumes (left: 0.48 vs 0.51 cm<jats:sup>3</jats:sup>; difference, 0.03; 95% CI, 0.004-0.05; right: 0.51 vs 0.55 cm<jats:sup>3</jats:sup>; difference, 0.04; 95% CI, 0.08-0.07) compared to controls. Methadone-exposed newborns showed significantly smaller white matter volume compared to controls, while buprenorphine-exposed newborns showed significantly smaller right amygdala volume than controls. Compared to controls, newborns exposed to opioids only and those exposed to opioids plus other substances both showed significant reductions in volumes of cortical and deep gray matter, cerebellum, brainstem, right amygdala, and total brain. Polysubstance-exposed newborns additionally showed smaller volumes in white matter and the left amygdala compared to controls.Conclusions and RelevanceIn a large cohort of antenatally opioid-exposed newborns, there were significant reductions in g","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"63 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Insights Into Fetal Growth in Twins-Pathology or Benign Adaptation?","authors":"Nir Melamed, Liran Hiersch","doi":"10.1001/jamapediatrics.2025.0113","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0113","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable Model of Early Intervention and Telerehabilitation for Children With Cerebral Palsy in Rural Bangladesh","authors":"Mahmudul Hassan Al Imam, Israt Jahan, Nuruzzaman Khan, Delwar Akbar, Shafiul Islam, Mohammad Muhit, Nadia Badawi, Gulam Khandaker","doi":"10.1001/jamapediatrics.2025.0150","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0150","url":null,"abstract":"ImportanceAccess to early intervention and rehabilitation services among children with cerebral palsy (CP) remains limited in Bangladesh, which demands an innovative and sustainable service delivery model.ObjectiveTo evaluate the effectiveness of the Sustainable Model of Early Intervention and Telerehabilitation for Children With CP (SMART-CP) model compared with usual care in improving access to and utilization of early diagnosis, early intervention, and rehabilitation services in rural Bangladesh.Design, Setting, and ParticipantsThis was a 2-arm cluster randomized clinical trial, with 8 clusters (ie, subdistricts) randomly allocated to the intervention (SMART-CP model) or control arm. The setting was in Sirajganj, Bangladesh, and included children with CP 18 years or younger. Outcomes were measured at 0 and 12 months, and an intention-to-treat analysis was conducted. Data were analyzed from December 2023 to May 2024.InterventionsThe SMART-CP model comprised (1) a rural referral network involving key informants and caregiver peer groups (called <jats:italic>mPower</jats:italic> or mothers’ power), (2) subdistrict level SMART-CP centers, and (3) telerehabilitation services. Children in the intervention arm received weekly goal-directed therapy, mPower group meetings every 2 weeks, and monthly telerehabilitation sessions.Main Outcomes and MeasuresThe primary outcome was whether a child with CP accessed any form of rehabilitation services, with secondary outcomes analyzed as hypothesis generating.ResultsOverall, 968 children with CP (mean [SD] age, 7.9 [4.9] years; 581 male [60.0%]) were enrolled, with 500 in the intervention arm and 468 in the control arm. Between baseline and endline, rehabilitation services uptake significantly increased in the intervention arm (70.2% [351 of 500] vs 99.4% [497 of 500]), compared with the control arm (63.9% [299 of 468] vs 68.2% [319 of 468]; <jats:italic>P</jats:italic> <.001). Children in the intervention arm were 1.5 times more likely to access rehabilitation than the control arm. Secondary analyses suggested that the intervention arm also facilitated early CP diagnosis (mean [SD] diagnosis time, 2.0 [2.0] years vs 3.8 [3.3] years; Cohen <jats:italic>d</jats:italic> = −0.7) and initiation of rehabilitation (mean [SD] rehabilitation time, 1.8 [1.8] years vs 3.6 [2.4] years; Cohen <jats:italic>d</jats:italic> = −0.9). Additionally, higher therapy session counts (mean [SD] session counts, 23.4 [31.7] vs 4.3 [20.8]; Cohen <jats:italic>d</jats:italic> = 0.7), increased assistive device utilization (20.8% [104 of 500] vs 3.0% [14 of 468]; risk ratio, 0.82; 95% CI, 0.78-0.86; <jats:italic>P</jats:italic> < .001), and lower out-of-pocket expenditure per month (mean [SD] expenditure, $1.5 [$1.6] vs $2.9 [$5.1]; Cohen <jats:italic>d</jats:italic> = −0.4) were found in the intervention arm. No significant difference in clinical outcomes and mortality rates was observed between the intervention and ","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"6 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal Body Composition in Twins and Singletons","authors":"Jessica L. Gleason, Wesley Lee, Zhen Chen, Kathryn A. Wagner, Dian He, William A. Grobman, Roger B. Newman, Seth Sherman, Robert Gore-Langton, Edward Chien, Luis Goncalves, Katherine L. Grantz","doi":"10.1001/jamapediatrics.2025.0116","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0116","url":null,"abstract":"ImportanceAn emerging paradigm attributes third-trimester fetal growth deceleration in uncomplicated twin pregnancies to an evolutionary adaptive process. Evaluating longitudinal fetal soft-tissue development may provide important insights into differential fetal growth trajectories between twins and singletons.ObjectiveTo compare twin vs singleton lean and fat tissue growth across pregnancy.Design, Setting, and ParticipantsProspective cohort study of dichorionic twins and singletons with serial ultrasound scans to chart fetal growth (2009-2013) and collect fetal volume data to measure fat and lean tissue (2015-2019) in 12 US clinical centers. Participants were individuals with singleton (n = 2802 enrolled) and twin (n = 171 pairs enrolled) pregnancies who generally had no chronic disease. Data analysis was performed from September 2023 to June 2024.ExposureTwin status.Main Outcomes and MeasuresAbdominal area, maximum abdominal subcutaneous tissue thickness, fractional thigh volume, fractional lean thigh volume, fractional fat thigh volume, midthigh area (including lean and fat components), ratio of fractional fat thigh volume to fractional thigh volume, and ratio of midthigh fat area to midthigh area, measured up to 6 times between 15 and 37 weeks’ gestation.ResultsAnalyses included 315 twin and 2604 singleton fetuses. The mean (SD) maternal age at delivery was 31.3 (6.1) years for twins and 28.2 (5.5) years for singletons, with a mean (SD) gestational age at delivery of 35.2 (4.2) weeks for twins and 39.2 (1.7) weeks for singletons. Mean twin abdominal measurements were significantly smaller than those of singletons between 25 and 37 weeks’ gestation for area (difference at 25 weeks, −48.6 [95% CI, −102.2 to −5.1] mm<jats:sup>2</jats:sup>; difference at 37 weeks, −480.5 [95% CI, −677.2 to −283.5] mm<jats:sup>2</jats:sup>) and between 27 and 37 weeks for maximum abdominal subcutaneous tissue thickness (difference at 27 weeks, −0.13 [95% CI, −0.24 to −0.02] mm; difference at 37 weeks, −0.40 [95% CI, −0.68 to −0.13] mm). Beginning at 15 weeks, fractional thigh volumes were significantly smaller for twins (mean fractional thigh volume difference, −0.11 [95% CI, −0.16 to −0.07] cm<jats:sup>3</jats:sup>; mean fractional fat thigh volume difference, −0.08 [95% CI,−0.12 to −0.05] cm<jats:sup>3</jats:sup>) relative to singletons, persisting through 37 weeks (mean fractional thigh volume difference, −7.55 [95% CI, −11.76 to −3.34] cm<jats:sup>3</jats:sup>; mean fractional fat thigh volume difference, −5.60 [95% CI, −8.37 to −2.82] cm<jats:sup>3</jats:sup>). Mean fractional lean thigh volume was significantly smaller for twins at 15 to 16 and 23 to 36 weeks. For the ratio of fractional fat thigh volume to fractional thigh volume, twins had a 2.7% to 4.2% smaller fat percentage between 15 and 37 weeks compared with singletons.Conclusions and RelevanceTwins had proportionally less fat tissue accumulation in utero compared with singletons as early as 15 week","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"34 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infant Mortality in the US—Sounding the Alarm","authors":"Philip A. Gruppuso, Emily F. Oster, Eli Y. Adashi","doi":"10.1001/jamapediatrics.2025.0369","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0369","url":null,"abstract":"This Viewpoint explores rising infant mortality rates in the US, including variation among states and associations with Medicaid expansion and abortion restrictions.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"61 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Following the Developing Brain Affected by Opioid Exposure.","authors":"Nethra K Madurai, Lauren L Jantzie","doi":"10.1001/jamapediatrics.2025.0274","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0274","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postvaccination Immunogenicity Among Pediatric Solid Organ Transplant Recipients.","authors":"Amy G Feldman, Brenda L Beaty, Jose A Ferrolino, Gabriela Maron, Saira A Ali, Leandra Bitterfeld, Adam Blatt, Mary Alice Boulware, Kathleen M Campbell, Emily Carr, Benhur Cetin, Shelley Chapman, Yeh-Chung Chang, Ryan Cunningham, Ronald H Dallas, Keerti L Dantuluri, Bryanna N Domenick, Noelle H Ebel, Scott Elisofon, Rima Fawaz, Marc Foca, Hayley A Gans, Vani V Gopalareddy, Nitika A Gupta, Katherine Harmann, Jessica Hollenbeck, Anna R Huppler, Catalina Jaramillo, Nagraj Kasi, Nanda Kerkar, Stacee Lerret, Steven J Lobritto, M James Lopez, Alisha Mavis, Sonia Mehra, Sindhu Mohandas, Flor M Munoz, Krupa R Mysore, Nadia Ovchinsky, Kerrigan Perkins, Stacy Postma, Lauren Pratscher, Elizabeth B Rand, Regina K Rowe, Daniel Ruderfer, Danielle Schultz, Katherine Sear, Megan L Sell, Tanvi S Sharma, Janis Stoll, Jerry Turner, Kristen G Valencia Deray, Dominique Villarin, Carly Weaver, Phoebe Wood, Olivia Woodford-Berry, George Yanni, Lara A Danziger-Isakov","doi":"10.1001/jamapediatrics.2024.6778","DOIUrl":"10.1001/jamapediatrics.2024.6778","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"467-471"},"PeriodicalIF":24.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks' Gestation: A Randomized Clinical Trial.","authors":"Roger G Faix, Abbot R Laptook, Seetha Shankaran, Barry Eggleston, Dhuly Chowdhury, Roy J Heyne, Abhik Das, Claudia Pedroza, Jon E Tyson, Courtney Wusthoff, Sonia L Bonifacio, Pablo J Sánchez, Bradley A Yoder, Matthew M Laughon, Diana M Vasil, Krisa P Van Meurs, Margaret M Crawford, Rosemary D Higgins, Brenda B Poindexter, Tarah T Colaizy, Shannon E G Hamrick, Lina F Chalak, Robin K Ohls, Michele E Hartley-McAndrew, Kevin Dysart, Carl T D'Angio, Ronnie Guillet, Stephen D Kicklighter, Waldemar A Carlo, Gregory M Sokol, Sara B DeMauro, Anna Maria Hibbs, C Michael Cotten, Stephanie L Merhar, Roopali V Bapat, Heidi M Harmon, Elizabeth Sewell, Sarah Winter, Girija Natarajan, Ricardo Mosquera, Susan R Hintz, Nathalie L Maitre, Kristen L Benninger, Myriam Peralta-Carcelen, Abbey C Hines, Andrea F Duncan, Deanne E Wilson-Costello, Andrea Trembath, William F Malcolm, Michele C Walsh","doi":"10.1001/jamapediatrics.2024.6613","DOIUrl":"10.1001/jamapediatrics.2024.6613","url":null,"abstract":"<p><strong>Importance: </strong>Hypothermia begun less than 6 hours after birth reduces death or disability in infants with encephalopathy due to hypoxia-ischemia at 36 or more weeks' gestation. Trials of hypothermia for infants younger than 36 weeks' gestation are lacking.</p><p><strong>Objective: </strong>To assess the probability that hypothermia at less than 6 hours after birth decreases death or disability in infants 33 to 35 weeks' gestation with moderate or severe hypoxic-ischemic encephalopathy.</p><p><strong>Design, setting, and participants: </strong>This randomized clinical trial was conducted between July 2015 and December 2022 for infants 33 to 35 weeks' gestation with moderate or severe hypoxic-ischemic encephalopathy at less than 6 hours after birth. Bayesian and intention-to-treat analyses were prespecified. The setting included 19 US Neonatal Research Network centers. Data were analyzed from March 2023 to November 2024.</p><p><strong>Interventions: </strong>Infants received unblinded targeted esophageal temperature management. Infants with hypothermia were maintained at 33.5 °C (acceptable 33-34 °C) for 72 hours and then rewarmed. Infants with normothermia were to be maintained at 37 °C (acceptable 36.5-37.3 °C).</p><p><strong>Main outcomes and measures: </strong>Composite of death or disability (moderate or severe) at 18 to 22 months' corrected age adjusted for level of encephalopathy and center.</p><p><strong>Results: </strong>A total of 168 infants with hypothermia and normothermia were preterm (mean [SD] age, 34.0 [0.8] weeks' gestation and 34.1 [0.8] weeks' gestation, respectively), while 46 of 88 (52%) and 45 of 80 (56%) were male, respectively. Randomization occurred at mean (SD) 4.5 (1.2) hours and 4.5 (1.3) hours for the groups with hypothermia and normothermia, respectively. The primary outcome occurred in 29 of 83 infants (35%) with hypothermia and 20 of 69 infants (29%) with normothermia (adjusted relative risk [hypothermic/normothermic], 1.11; 95% credibility interval, 0.74-2.00), and death occurred in 18 of 88 infants (20%) with hypothermia and 9 of 78 infants (12%) with normothermia (adjusted relative risk, 1.38; 95% credibility interval, 0.79-2.85). Bayesian analysis with neutral prior indicated 74% probability of increased death or disability and 87% probability of increased death with hypothermia.</p><p><strong>Conclusions and relevance: </strong>Among infants 33 to 35 weeks' gestation with hypoxic-ischemic encephalopathy, hypothermia at less than 6 hours' age did not reduce death or disability at 18 to 22 months' corrected age.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT01793129.</p>","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"396-406"},"PeriodicalIF":24.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adolescent Smartphone Use During School Hours.","authors":"Dimitri A Christakis, Gina Marie Mathew, David A Reichenberger, Isaac R Rodriguez, Benny Ren, Lauren Hale","doi":"10.1001/jamapediatrics.2024.6627","DOIUrl":"10.1001/jamapediatrics.2024.6627","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"475-478"},"PeriodicalIF":24.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}