JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1555
Amy J Houtrow, Angela M Garcia, Jason Edinger, Unoma Akamagwuna
{"title":"Disability Competent Care in Pediatric Milestones.","authors":"Amy J Houtrow, Angela M Garcia, Jason Edinger, Unoma Akamagwuna","doi":"10.1001/jamapediatrics.2024.1555","DOIUrl":"10.1001/jamapediatrics.2024.1555","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1832
Micheal Sandbank, James E Pustejovsky, Kristen Bottema-Beutel, Nicolette Caldwell, Jacob I Feldman, Shannon Crowley LaPoint, Tiffany Woynaroski
{"title":"Determining Associations Between Intervention Amount and Outcomes for Young Autistic Children: A Meta-Analysis.","authors":"Micheal Sandbank, James E Pustejovsky, Kristen Bottema-Beutel, Nicolette Caldwell, Jacob I Feldman, Shannon Crowley LaPoint, Tiffany Woynaroski","doi":"10.1001/jamapediatrics.2024.1832","DOIUrl":"10.1001/jamapediatrics.2024.1832","url":null,"abstract":"<p><strong>Importance: </strong>Health professionals routinely recommend intensive interventions (ie, 20-40 hours per week) for autistic children. However, primary research backing this recommendation is sparse and plagued by methodological flaws.</p><p><strong>Objective: </strong>To examine whether different metrics of intervention amount are associated with intervention effects on any developmental domain for young autistic children.</p><p><strong>Data sources: </strong>A large corpus of studies taken from a recent meta-analysis (with a search date of November 2021) of early interventions for autistic children.</p><p><strong>Study selection: </strong>Studies were eligible if they reported a quasi-experimental or randomized clinical trial testing the effects of a nonpharmacological intervention on any outcome in participant samples comprising more than 50% autistic children 8 years or younger.</p><p><strong>Data extraction and synthesis: </strong>Data were independently extracted by multiple coders. Meta-regression models were constructed to determine whether each index of intervention amount was associated with effect sizes for each intervention type, while controlling for outcome domain, outcome proximity, age of participants, study design, and risk of detection bias. Data were analyzed from June 2023 to February 2024. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.</p><p><strong>Main outcomes and measures: </strong>The primary predictor of interest was intervention amount, quantified using 3 different metrics (daily intensity, duration, and cumulative intensity). The primary outcomes of interest were gains in any developmental domain, quantified by Hedges g effect sizes.</p><p><strong>Results: </strong>A total of 144 studies including 9038 children (mean [SD] age, 49.3 [17.2] months; mean [SD] percent males, 82.6% [12.7%]) were included in this analysis. None of the meta-regression models evidenced a significant, positive association between any index of intervention amount and intervention effect size when considered within intervention type.</p><p><strong>Conclusions and relevance: </strong>Findings of this meta-analysis do not support the assertion that intervention effects increase with increasing amounts of intervention. Health professionals recommending interventions should be advised that there is little robust evidence supporting the provision of intensive intervention.</p>","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11197026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1388
Samuele Cortese, Jae Il Shin, Marco Solmi
{"title":"Testing the Concerns Regarding the Global Burden of Disease.","authors":"Samuele Cortese, Jae Il Shin, Marco Solmi","doi":"10.1001/jamapediatrics.2024.1388","DOIUrl":"10.1001/jamapediatrics.2024.1388","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1840
Erica C Prochaska, Shaoming Xiao, Elizabeth Colantuoni, Reese H Clark, Julia Johnson, Sagori Mukhopadhyay, Ibukunoluwa C Kalu, Danielle M Zerr, Patrick J Reich, Jessica Roberts, Dustin D Flannery, Aaron M Milstone
{"title":"Hospital-Onset Bacteremia Among Neonatal Intensive Care Unit Patients.","authors":"Erica C Prochaska, Shaoming Xiao, Elizabeth Colantuoni, Reese H Clark, Julia Johnson, Sagori Mukhopadhyay, Ibukunoluwa C Kalu, Danielle M Zerr, Patrick J Reich, Jessica Roberts, Dustin D Flannery, Aaron M Milstone","doi":"10.1001/jamapediatrics.2024.1840","DOIUrl":"10.1001/jamapediatrics.2024.1840","url":null,"abstract":"<p><strong>Importance: </strong>The Centers for Disease Control and Prevention plans to introduce hospital-onset bacteremia (HOB) as a health care-associated infection measure. The epidemiology and clinical characteristics of HOB among infants admitted to the neonatal intensive care unit (NICU) are unknown.</p><p><strong>Objective: </strong>To estimate the rate of HOB among infants admitted to the NICU, measure the association of HOB risk with birth weight group and postnatal age, and estimate HOB-attributable mortality.</p><p><strong>Design, setting, and participants: </strong>This retrospective multicenter cohort study and emulated trial from 2016 to 2021 included a convenience sample of 322 NICUs in the United States. Participants were infants admitted to participating NICUs for 4 or more days.</p><p><strong>Exposures: </strong>The primary exposures were birth weight and postnatal age. Additional exposures included small for gestational age and central line presence.</p><p><strong>Main outcomes and measures: </strong>The primary study outcomes were HOB and HOB-attributable mortality.</p><p><strong>Results: </strong>Of 451 443 included infants, 250 763 (55.6%) were male, 200 680 (44.4%) were female, and 62 091 (13.8%) were born 1500 g or less. Of 9015 HOB events that occurred among 8356 infants (2%) during 8 163 432 days at risk (unadjusted incidence rate, 1.1 per 1000 patient-days; 95% CI, 1.0-1.2), 4888 HOB events (54.2%) occurred in the absence of a central line. Within the first 2 weeks after birth, the HOB rate was 14.2 per 1000 patient-days (95% CI, 12.6-16.1) among infants born 750 g or less, to 0.4 events per 1000 patient-days among infants born more than 2500 g (95% CI, 0.4-0.5). Among infants born 750 g or less, the relative HOB risk decreased by 90% after day 42 compared with days 4 to 14 (incidence rate ratio [IRR], 0.10; 95% CI, 0.1-0.1). Conversely, among infants born more than 2500 g, the relative HOB risk increased by 50% after day 42 compared with days 4 to 14 (IRR, 1.5, 95% CI, 1.2-1.9). Compared with otherwise similar infants without HOB, infants with HOB had an absolute difference in attributable mortality of 5.5% (95% CI, 4.7-6.3).</p><p><strong>Conclusions and relevance: </strong>This study found that HOB events in the NICU are associated with increased mortality. Birth weight is an important risk factor for HOB; however, the relative rate of HOB decreases over postnatal age among low-birth-weight infants and increases among infants born more than 2500 g. Identifying strategies to prevent HOB and programs to decrease HOB risk are urgently needed to reduce infant mortality.</p>","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11197452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1324
Vijay Vasudevan, Anne Nagel, Lindsay A Thompson
{"title":"What Parents Need to Know About Autism Screening and Early Treatment.","authors":"Vijay Vasudevan, Anne Nagel, Lindsay A Thompson","doi":"10.1001/jamapediatrics.2024.1324","DOIUrl":"10.1001/jamapediatrics.2024.1324","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1559
Jordan Tyris, Laura M Gottlieb
{"title":"Clinical Care Adjustments Based on Socioeconomic Adversity.","authors":"Jordan Tyris, Laura M Gottlieb","doi":"10.1001/jamapediatrics.2024.1559","DOIUrl":"10.1001/jamapediatrics.2024.1559","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1688
David E Hall, Kenneth B Roberts, Evan Charney
{"title":"Rethinking the Timetable for Spontaneous Closure of Pediatric Umbilical Hernia.","authors":"David E Hall, Kenneth B Roberts, Evan Charney","doi":"10.1001/jamapediatrics.2024.1688","DOIUrl":"10.1001/jamapediatrics.2024.1688","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2024-08-01DOI: 10.1001/jamapediatrics.2024.1391
Naveed Rabbani, Laura Burckett Patane, Jonathan Hatoun, Emily Trudell Correa, Louis Vernacchio
{"title":"Pediatric Primary Care Billing Trends After the 2021 Evaluation and Management Coding Changes.","authors":"Naveed Rabbani, Laura Burckett Patane, Jonathan Hatoun, Emily Trudell Correa, Louis Vernacchio","doi":"10.1001/jamapediatrics.2024.1391","DOIUrl":"10.1001/jamapediatrics.2024.1391","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":null,"pages":null},"PeriodicalIF":24.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}