JAMA Pediatrics最新文献

{"title":"Sampling Errors in Study of Distribution of Pediatric Subspecialists and Patient Proximity to Specialized Care.","authors":"Adam Turner","doi":"10.1001/jamapediatrics.2025.1376","DOIUrl":"10.1001/jamapediatrics.2025.1376","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"923"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data and Analysis Concerns in Trial of Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants-Reply.","authors":"Roger G Faix, Abbot R Laptook, Seetha Shankaran","doi":"10.1001/jamapediatrics.2025.1441","DOIUrl":"10.1001/jamapediatrics.2025.1441","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"925-926"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Errors in Reported Effect Sizes.","authors":"","doi":"10.1001/jamapediatrics.2025.1466","DOIUrl":"10.1001/jamapediatrics.2025.1466","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"930"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Firearm Laws and Pediatric Mortality in the US.","authors":"Jeremy Samuel Faust, Ji Chen, Shriya Bhat, Onyekachi Otugo, Miranda Yaver, Benjamin Renton, Alexander Junxiang Chen, Zhenqiu Lin, Harlan M Krumholz","doi":"10.1001/jamapediatrics.2025.1363","DOIUrl":"10.1001/jamapediatrics.2025.1363","url":null,"abstract":"<p><strong>Importance: </strong>Firearms are the leading cause of death in US children and adolescents, but little is known about whether the overall legal landscape was associated with excess mortality after a landmark US Supreme Court decision in 2010.</p><p><strong>Objective: </strong>To measure excess mortality due to firearms among US children aged 0 to 17 years after the McDonald v Chicago US Supreme Court decision (2010).</p><p><strong>Design, setting, and participants: </strong>An excess mortality analysis was conducted using the US Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (WONDER) database before and after McDonald v Chicago, the landmark 2010 US Supreme Court decision on firearms regulation. States were divided into 3 groups based on legal actions taken before and since 2010, most permissive, permissive, and strict. Firearm mortality trends before (1999-2010) and after (2011-2023) were determined and compared across the 3 groups for all intents and by intent (homicide and suicide). Subgroup analysis by observed race and ethnicity was conducted. For each US state, pre-and post-McDonald v Chicago all-intent pediatric firearm mortality incident rates were compared. These data were analyzed January 2011 through December 2023.</p><p><strong>Exposure: </strong>The pre- and post-McDonald v Chicago legal landscape.</p><p><strong>Main outcomes and measures: </strong>Excess mortality during the post-McDonald v Chicago period.</p><p><strong>Results: </strong>During the post-McDonald v Chicago period (2011-2023), there were 6029 excess firearm deaths (incidence rate [IR], 158.6 per million population; 95% CI, 154.8-162.5) in the most permissive group. In the permissive group, there were 1424 excess firearm deaths (IR, 107.5 per million person-years; 95% CI, 103.8-111.3). In the strict group, there were -55 excess firearm deaths (IR, -2.5 per million person-years; 95% CI, -5.8 to 0.8). Non-Hispanic Black populations had the largest increase in firearm mortality in the most permissive and permissive state groupings. Four states (California, Maryland, New York, and Rhode Island) had decreased pediatric firearm mortality after McDonald v Chicago, all of which were in the strict firearms law group.</p><p><strong>Conclusion: </strong>States in the most permissive and permissive firearm law categories experienced greater pediatric firearm mortality during the post-McDonald v Chicago era. Future work should focus on determining which types of laws conferred the most harm and which offered the most protection.</p>","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"896-902"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exception From Informed Consent in Pediatric Trials.","authors":"Jay R Malone, Marissa Tremoglie-Barkowski, Barbara A Gaines, Christine M Leeper","doi":"10.1001/jamapediatrics.2025.1324","DOIUrl":"10.1001/jamapediatrics.2025.1324","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"815-816"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Errors in Editorial.","authors":"","doi":"10.1001/jamapediatrics.2025.2344","DOIUrl":"10.1001/jamapediatrics.2025.2344","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"930"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptance and Commitment Therapy-Based Parenting Program in Children With Co-Occurring Asthma and ADHD: A Randomized Clinical Trial.","authors":"Yuen Yu Chong, Wai Tong Chien, Kenneth P Fung, Sui Ping Leung, Shu Yan Lam","doi":"10.1001/jamapediatrics.2025.1313","DOIUrl":"10.1001/jamapediatrics.2025.1313","url":null,"abstract":"<p><strong>Importance: </strong>Co-occurring asthma and attention-deficit/hyperactivity disorder (ADHD) in children increase caregiving complexity and health care use, underscoring the need for holistic interventions addressing both conditions.</p><p><strong>Objective: </strong>To examine the efficacy of an acceptance and commitment therapy-based parenting program (ACT-PAM) on health outcomes in children with asthma and ADHD and their parents over 12 months postintervention.</p><p><strong>Design, setting, and participants: </strong>This assessor-blinded randomized clinical trial was conducted from April 1, 2021, to August 31, 2023, at a Hong Kong public hospital and enrolled 118 parents of children with asthma and comorbid ADHD. Participants were randomized to receive either ACT-PAM plus standard asthma care as treatment as usual (TAU) or TAU alone. Data were analyzed from December 1, 2023, to March 31, 2024, using an intention-to-treat principle.</p><p><strong>Interventions: </strong>Six ACT-PAM group sessions focused on acceptance, mindfulness, values-based parenting, and asthma management.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was the number of unscheduled health care visits for asthma exacerbations over 12 months. Secondary outcomes included asthma control (via the Childhood Asthma Control Test [C-ACT]), ADHD symptoms in children (via parent-rated scores on Strengths and Weaknesses of ADHD Symptoms and Normal Behaviors [SWAN] scale), parental psychological inflexibility, and asthma management self-efficacy.</p><p><strong>Results: </strong>Among 118 parent-child dyads (mean [SD] parent age, 40.3 [5.5] years; mean [SD] child age, 7.9 [2.2] years; 108 female parents [92%] and 31 female children [26%]), ACT-PAM plus TAU significantly reduced unscheduled health care visits compared with TAU alone (adjusted mean difference [aMD], -0.8 visits; 95% CI, -1.6 to -0.1; adjusted incidence rate ratio, 0.33; 95% CI, 0.19-0.55). C-ACT scores improved (aMD, 4.4; 95% CI, 2.5-6.5; Cohen d, 1.40; 95% CI, 1.10-1.79), while parent-rated SWAN combined scores decreased (aMD, -0.5; 95% CI, -0.8 to -0.3; Cohen d, -0.94; 95% CI, -1.32 to -0.56). Parental psychological inflexibility (aMD, -10.0; 95% CI, -15.6 to -4.5; Cohen d, -1.08; 95% CI, -1.47 to -0.69) and asthma management self-efficacy (aMD, 0.8; 95% CI, 0.4-1.2; Cohen d, 1.20; 95% CI, 0.78-1.68) were also improved with the combination of ACT-PAM and TAU.</p><p><strong>Conclusions and relevance: </strong>In this randomized clinical trial, ACT-PAM reduced health care use, improved asthma control, and alleviated ADHD symptoms, demonstrating its efficacy in managing pediatric asthma with comorbid ADHD.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT04991649.</p>","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"846-856"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraindications to Immunization of Solid Organ Transplant Patients With Varicella Vaccine.","authors":"Charles Grose","doi":"10.1001/jamapediatrics.2025.1307","DOIUrl":"10.1001/jamapediatrics.2025.1307","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"922"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effects of a Responsive Parenting Intervention on Child Weight Outcomes Through Age 9 Years: The INSIGHT Randomized Clinical Trial.","authors":"Ian M Paul, Jennifer M Barton, Stephanie Anzman-Frasca, Emily E Hohman, Orfeu M Buxton, Lindsey B Hess, Jennifer S Savage","doi":"10.1001/jamapediatrics.2024.6897","DOIUrl":"10.1001/jamapediatrics.2024.6897","url":null,"abstract":"<p><strong>Importance: </strong>Behavioral interventions to treat childhood obesity have had limited success. Primary prevention is desirable, but whether intervention effectiveness can be sustained is unknown.</p><p><strong>Objective: </strong>To examine the effect of an intervention designed for the primary prevention of obesity and delivered through age 2 years on weight outcomes through age 9 years.</p><p><strong>Design, setting, and participants: </strong>A longitudinal observation of a single-center randomized clinical trial comparing a responsive parenting intervention vs a home safety intervention (control) among primiparous mother-child dyads who completed the assessment at age 3 years with follow-up to age 9 years. All data were analyzed from January 21 to November 15, 2024.</p><p><strong>Interventions: </strong>Research nurses conducted 4 home visits during infancy and research center visits at ages 1 and 2 years totaling less than 10 contact hours. The responsive parenting curriculum focused on feeding, sleep, interactive play, and emotion regulation.</p><p><strong>Main outcomes and measures: </strong>The primary outcome is body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) across 4 assessments from age 3 through 9 years, with the assessment of study group differences using repeated-measures analysis. A test for an interaction between sex and study group was planned. Secondary outcomes include BMI z scores and prevalence of overweight (BMI ≥85th to <95th percentile) and obesity (BMI ≥95th percentile) at 5, 6, and 9 years.</p><p><strong>Results: </strong>Of the 232 primiparous mother-child dyads (116 per group) (7 Asian [3%], 11 Black [5%], 1 Native Hawaiian or Other Pacific Islander [0.4%], 207 White [89%], and 6 children with other race and ethnicity [including Asian, Indian, Hispanic, Dominican, and other race; 2.5%]; 121 male children [52%]), 177 (76%) had anthropometric data at age 9 years. From ages 3 to 9 years, children in the responsive parenting group had a lower mean (SE) BMI than controls (16.59 [0.18] vs 16.95 [0.18]; absolute difference, -0.36; P = .049). Sex moderated this effect; female participants in the responsive parenting group had a lower mean (SE) BMI than female participants in the control group (16.31 [0.23] vs 17.24 [0.22]; absolute difference, -0.93; P = .002), with no group differences among male participants. Cross-sectional analyses revealed no differences in BMI z scores or prevalence of overweight or obesity at ages 5, 6, and 9 years between the responsive parenting group and the control group.</p><p><strong>Conclusions and relevance: </strong>An early-life responsive parenting intervention resulted in lower BMI from age 3 to 9 years compared with a control intervention. This group difference was driven by effects on female participants, with differences appearing to dissipate over time. A life-course approach may be required to sustain the benefits of early-life","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"827-835"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data and Analysis Concerns in Trial of Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants.","authors":"Floris Groenendaal","doi":"10.1001/jamapediatrics.2025.1444","DOIUrl":"10.1001/jamapediatrics.2025.1444","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"924"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}