JAMA PediatricsPub Date : 2026-04-01DOI: 10.1001/jamapediatrics.2026.0102
{"title":"Errors in Results and Supplement.","authors":"","doi":"10.1001/jamapediatrics.2026.0102","DOIUrl":"10.1001/jamapediatrics.2026.0102","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"462"},"PeriodicalIF":18.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-04-01DOI: 10.1001/jamapediatrics.2026.0150
Dimitri A Christakis
{"title":"Editor's Note on CONSORT-C and SPIRIT-C Guidelines.","authors":"Dimitri A Christakis","doi":"10.1001/jamapediatrics.2026.0150","DOIUrl":"10.1001/jamapediatrics.2026.0150","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"440"},"PeriodicalIF":18.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-30DOI: 10.1001/jamapediatrics.2026.0512
Wenming Shi,Lena Kan,Tongshuai Wang,Yongzhen Li,Xingyun Wang
{"title":"Parent-Reported Chronic Pain in Children With and Without Developmental Disabilities.","authors":"Wenming Shi,Lena Kan,Tongshuai Wang,Yongzhen Li,Xingyun Wang","doi":"10.1001/jamapediatrics.2026.0512","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2026.0512","url":null,"abstract":"ImportanceAlthough pediatric pain can impede healthy development throughout adulthood, the prevalence of chronic pain among US children with developmental disabilities remains unclear.ObjectiveTo evaluate parent-reported chronic pain prevalence and the association between developmental disabilities and chronic pain in US children and adolescents (hereinafter, children).Design, Setting, and ParticipantsThis national survey study included 263 168 children aged 3 to 17 years who participated in the 2016-2023 National Survey of Children's Health (NSCH). Data were analyzed from June 2025 to August 2025.ExposuresReporting any of the 10 developmental disabilities included in the NSCH: seizure, cerebral palsy, autism, attention-deficit/hyperactivity disorder, vision, hearing, and/or speech delay, intellectual and/or learning disability, and developmental delay.Main Outcomes and MeasuresThe weighted prevalence of parent-reported chronic pain in children with or without any of these 10 disabilities was calculated across the study period and by year. Logistic regression models were applied to examine the association between various categories of developmental disabilities and pain among US children as well as potential health disparities.ResultsThis study included a weighted sample of 224 467 664 children; of them, 135 848 (51.1%) were male with a mean (SD) age of 10.2 (4.5) years. Approximately 18.7% of children reported having at least 1 disability. The weighted prevalence of parent-reported chronic pain was higher in children with at least 1 developmental disability compared to peers without a disability (13.2% vs 5.5%) over the study period. Adjusted analyses revealed significant associations between any of the disabilities and parent-reported chronic pain, with an odds ratio of 2.31 (95% CI, 2.14-2.49). Similar positive associations were also observed for all disability categories, particularly seizure and cerebral palsy. Moreover, higher odds of parent-reported chronic pain were associated with lower levels of parental education and family income, or more adverse childhood experiences.Conclusion and RelevanceThe findings in this study indicate that children with diverse developmental disabilities were more likely to have parent-reported chronic pain, and this likelihood was associated with several socioeconomic factors. These findings provide important insights into targeted screening and interventions for pain in pediatric populations with developmental disabilities.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"7 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147536384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-30DOI: 10.1001/jamapediatrics.2026.0394
Kyle A Gavulic,John E Pachankis,Daniel G Aaron
{"title":"\"Conversion Therapy\" in the US-Progress, Missed Opportunities, and Future Directions.","authors":"Kyle A Gavulic,John E Pachankis,Daniel G Aaron","doi":"10.1001/jamapediatrics.2026.0394","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2026.0394","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"20 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147536382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-30DOI: 10.1001/jamapediatrics.2026.0533
Mingzheng Hu,Tiffany Truong,Sufen Zhu,Joaquim Vidiella-Martin,Samantha Johnson,Maria A Quigley,Stavros Petrou
{"title":"Cognitive and Educational Outcomes After Preterm Birth or Low Birth Weight: An Umbrella Review and Meta-Analysis.","authors":"Mingzheng Hu,Tiffany Truong,Sufen Zhu,Joaquim Vidiella-Martin,Samantha Johnson,Maria A Quigley,Stavros Petrou","doi":"10.1001/jamapediatrics.2026.0533","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2026.0533","url":null,"abstract":"ImportanceAdvances in perinatal care have improved survival for infants born preterm (<37 weeks' gestation) or with low birth weight (<2500 g), but these individuals remain at increased risk of poorer cognitive and educational outcomes.ObjectiveTo synthesize evidence from systematic reviews on both cognitive and educational outcomes in individuals after preterm birth or with low birth weight using an umbrella review and meta-analysis approach.Data Sources and Study SelectionThe PubMed, Embase, ERIC, RePEc, EconLit, and Google Scholar databases were searched from inception through April 2025 for systematic reviews examining associations between preterm birth or low birth weight and cognitive or educational outcomes.Data Extraction and SynthesisTwo reviewers independently selected studies, extracted data, and evaluated study quality and risk of bias (following the guidelines from the Joanna Briggs Institute). The effect sizes from the original primary studies included in meta-analyses were reanalyzed and converted to equivalent Hedges g effect sizes. Data were pooled using random-effects models. The subgroup analyses examined associations by gestational age, birth weight, and age. Narrative synthesis supplemented quantitative findings.Main Outcomes and MeasuresGeneral cognitive ability (intelligence quotient [IQ]) and 4 domains of educational outcomes (academic attainment, type and length of schooling, need for additional educational support, and educational costs).ResultsForty systematic reviews (22 with meta-analyses and 18 with narrative syntheses) were included, yielding 788 reanalyzed effect estimates. Preterm birth or low birth weight was associated with lower IQ (Hedges g, -0.65 [95% CI, -0.69 to -0.61]), poorer attainment in reading (Hedges g, -0.65 [95% CI, -0.87 to -0.43]), lower performance in mathematics (Hedges g, -0.77 [95% CI, -1.03 to -0.50]), lower performance in spelling (Hedges g, -0.56 [95% CI, -0.65 to -0.46]), and greater need for special educational support (Hedges g, 0.58 [95% CI, 0.41 to 0.74]). The associations were stronger at earlier gestational ages and lower birth weights, appeared to attenuate during adolescence, and remained evident into adulthood. Evidence on schooling and educational costs was limited but suggested lower school completion rates and higher educational costs.Conclusions and RelevanceThis umbrella review and meta-analysis found that preterm birth and low birth weight were associated with persistent cognitive and educational disadvantages across the life course, underscoring the importance of early identification and long-term monitoring to inform health and educational planning.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"1 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147536383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-30DOI: 10.1001/jamapediatrics.2025.6312
E. Meryl Shychuk, Elyse M. C. Harris, Lindsay A. Thompson
{"title":"What Parents Need to Know About Moles in Children","authors":"E. Meryl Shychuk, Elyse M. C. Harris, Lindsay A. Thompson","doi":"10.1001/jamapediatrics.2025.6312","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.6312","url":null,"abstract":"This <jats:italic toggle=\"yes\">JAMA Pediatrics</jats:italic> Patient Page describes moles in children, including when children should see a skin specialist for evaluation.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"48 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147536542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-23DOI: 10.1001/jamapediatrics.2026.0343
Resthie R Putri,Pernilla Danielsson,Emilia Hagman,Claude Marcus
{"title":"Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity.","authors":"Resthie R Putri,Pernilla Danielsson,Emilia Hagman,Claude Marcus","doi":"10.1001/jamapediatrics.2026.0343","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2026.0343","url":null,"abstract":"ImportanceMetabolically healthy obesity (MHO) in children has been considered a low-risk phenotype, potentially not requiring treatment. However, their long-term cardiometabolic outcomes remain unclear.ObjectiveTo compare the occurrence of type 2 diabetes, hypertension, dyslipidemia, and mortality up to young adulthood in children with metabolically healthy obesity (MHO), metabolically unhealthy obesity (MUO), and general population peers, and to investigate the association between obesity treatment response and disease risk.Design, Setting, and ParticipantsThis was a prospective cohort study including children undergoing obesity treatment recorded in the Swedish Childhood Obesity Treatment Register (BORIS) between 1997 and 2020 and their general population comparators, linked with national registers. Children in the cohort with obesity were aged 7 to 17 years at obesity treatment initiation and had complete cardiometabolic data. General population comparators were matched (ratio 1:5) based on sex, birth year, and residential area. Study data were analyzed from February to March 2025.ExposuresExposures included metabolically healthy obesity (MHO), defined as the absence of high blood pressure, impaired fasting glycemia, elevated transaminases, elevated triglycerides, and low high-density lipoprotein cholesterol; otherwise, children were categorized as having metabolically unhealthy obesity (MUO).Main Outcomes and MeasuresType 2 diabetes, hypertension, dyslipidemia, and mortality up to age 30 years.ResultsA total of 7275 children (median [first quartile {Q1}-third quartile {Q3}] age, 11.1 [9.1-13.5] years; 4004 male [55.0%]) were included, along with 35 636 general population comparators (median [Q1-Q3] age, 11.1 [9.1-13.5] years; 19 596 male [55.0%]). MHO at baseline was present in 3626 children (49.8%; median [Q1-Q3] age, 10.6 [8.8-12.8] years; 1981 male [54.6%]), and MUO was present in 3649 children (50.2%; median [Q1-Q3] age, 11.6 [9.4-14.0] years; 2023 male [55.4%]). By age 30 years, cumulative incidences were as follows: type 2 diabetes (MHO, 9.1%; MUO, 16.8%; general population, 0.5%), hypertension (MHO, 10.8%; MUO, 18.3%; general population, 3.7%), and dyslipidemia (MHO, 5.3%; MUO, 12.7%; general population, 0.9%). A reduction of at least 0.25 body mass index (BMI) z score was associated with reduced incidence rate ratio (IRR) of type 2 diabetes (IRR, 0.22; 95% CI, 0.14-0.35), hypertension (IRR, 0.56; 95% CI, 0.34-0.93), and dyslipidemia (IRR, 0.28; 95% CI, 0.14-0.57), with similar risk reduction for MHO and MUO.Conclusions and RelevanceResults of this cohort study reveal that a reduction in BMI z score of at least 0.25 was associated with similar risk reductions for both MHO and MUO. Children with MHO face a substantially increased cardiometabolic disease risk already as young adults compared with the general population. Hence, obesity treatment should be recommended for all children with obesity, regardless of initial metabolic status.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"92 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147495010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA PediatricsPub Date : 2026-03-23DOI: 10.1001/jamapediatrics.2026.0259
Cassie Burley,Carly E Milliren,Jessica A Lin,Tracy K Richmond
{"title":"COVID-19-Related Changes in Volume of Adolescents and Young Adults With Eating Disorders Requiring Hospitalization.","authors":"Cassie Burley,Carly E Milliren,Jessica A Lin,Tracy K Richmond","doi":"10.1001/jamapediatrics.2026.0259","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2026.0259","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"15 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147495014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}