JAMA Pediatrics最新文献

{"title":"Exploring Challenges With Widespread Use of GLP-1-Based Therapies for Adolescents and Young Adults.","authors":"Jing Luo,Mary Ellen Vajravelu,Stacie B Dusetzina","doi":"10.1001/jamapediatrics.2025.2469","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2469","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"58 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplemental Donor Milk vs Infant Formula in Moderate to Late Preterm Infants: A Randomized Clinical Trial.","authors":"Alice R Rumbold,Melissa M Lai,Deanne August,Pieter Koorts,Tim Donovan,Lisa Yelland,Maria Makrides,Alana R Cuthbert,Laura D Klein,Teresa Ginis,Aya Al Gharram,Susie Jones,Laura Summers,Andrew McPhee,Amy Keir","doi":"10.1001/jamapediatrics.2025.2365","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2365","url":null,"abstract":"ImportanceHigh-quality evidence supports the use of pasteurized donor human milk (donor milk) in very preterm infants with insufficient maternal milk available. However, evidence to guide the use of donor milk in more mature preterm infants is lacking.ObjectiveTo compare the effect of donor milk vs term infant formula, used to supplement insufficient maternal milk, on the time to establish full enteral feeds in moderate to late preterm infants.Design, Setting, and ParticipantsThis multisite, blinded randomized clinical trial was conducted from July 6, 2021, to April 5, 2023, at 2 Australian neonatal units. Infants 4 days old or younger, born between 32 + 0 and 36 + 6 weeks' gestation, with a birth weight of 1500 g or higher, and admitted to a neonatal unit were eligible if they were clinically stable, ready to commence or had commenced enteral feeds, and had insufficient maternal milk available. Infants were followed up until 6-month corrected age (CA). Follow-up assessments until 6-month CA were completed by December 4, 2023, and data analyses were completed by January 23, 2025.InterventionInfants were randomly assigned to receive supplemental donor milk or term formula for up to 8 days, stratified by site and gestational age at birth.Main Outcomes and MeasuresThe primary outcome was time to full enteral feeds (defined as 150 mL/kg/day). Secondary outcomes included feed intolerance, growth, body composition, breast milk feeding, and hospital readmissions to 6-month CA.ResultsOf 201 infants randomized (99 to donor milk, 102 to formula), the mean (SD) birth gestational age was 34.6 (1.2) weeks, mean (SD) birth weight was 2267.1 (450.8) g, 88 infants (43.8%) were female, and 75 infants (37.3%) were a twin or triplet. Mean (SD) time to reach full enteral feeds did not differ between groups (donor milk group: 5.7 [2.6] days; formula group: 5.8 [3.4] days; adjusted mean difference, -0.07; 95% CI, -0.90 to 0.76). Secondary outcomes were similar between groups, except that infants in the donor milk group had a lower rate of birth weight regain compared with the formula group (mean [SD] time to regain in donor milk group: 10.7 [5.7] days; formula group: 8.4 [4.4] days; hazard ratio, 0.65; 95% CI, 0.47-0.88).Conclusions and RelevanceIn this multisite randomized clinical trial, supplemental donor milk did not reduce time to full enteral feeds in moderate to late preterm infants compared with term formula for up to 8 days.Trial Registrationanzctr.org.au Identifier: ACTRN12621000529842.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"149 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Further Considerations on EEG-Guided Pediatric Anesthesia.","authors":"Frank Fideler,Felix Neunhoeffer,Berthold Drexler","doi":"10.1001/jamapediatrics.2025.2433","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2433","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"76 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Universal Free School Meal Policies and Participation in the US National School Meal Programs.","authors":"Francesco Ramponi,Hui Zhou,Wendi Gosliner,Punam Ohri-Vachaspati,Dania Orta-Aleman,Lorrene Ritchie,Marlene Schwartz,Lindsey Turner,Stéphane Verguet,Juliana Cohen","doi":"10.1001/jamapediatrics.2025.2301","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2301","url":null,"abstract":"ImportanceSchool meals can support children's health and educational outcomes; however, in the US, only students from households with incomes at or below 185% of the federal poverty level qualify for free or reduced-price meals. Although the Community Eligibility Provision (CEP) enables schools in higher poverty areas to offer free meals to all students, many schools do not participate; the temporary implementation of federal Universal Free School Meal (UFSM) policies during the COVID-19 pandemic and subsequent state-level policies highlight the need for assessing their impact on participation rates in school meal programs.ObjectiveTo examine the impact of federal- and state-level UFSM and related policies on National School Lunch Program (NSLP) and School Breakfast Program (SBP) participation rates during and after the COVID-19 pandemic.Design, Setting, and ParticipantsThis comparative effectiveness research study used a natural experiment created by the COVID-19 pandemic to analyze school-level data from the 2019 to 2020 school-year period to the 2023 to 2024 school-year period. A difference-in-difference analysis with linear mixed-effects models was conducted to assess the impact of federal-level UFSM implementation and deimplementation and state-level policies on SBP and NSLP participation rates. School-level meal claims data were analyzed across 14 states with UFSM or related policies and 11 comparison states, and schools participating in the NSLP and the SBP were included in this analysis.ExposuresFederal UFSM policy, state-level UFSM policies, CEP participation, and limited expansions of free meal access.Main Outcomes and MeasuresParticipation rates in SBP and NSLP, measured as percentage-point changes over time.ResultsFederal UFSM during the COVID-19 pandemic increased NSLP and SBP participation by 10 percentage points (range, -8 to 18 percentage points) and 8 percentage points (range, 2-20 percentage points), respectively, where percentage points refers to absolute changes in participation rates. Deimplementation in school year 2022 to 2023 reduced participation by 12 percentage points (range, -15 to -4 percentage points) for NSLP and 10 percentage points (range, -18 to -4 percentage points) for SBP. States that maintained UFSM policies showed consistently higher participation rates compared with states that discontinued UFSM, with increases between 9 and 19 percentage points (NSLP) and between 5 and 26 percentage points (SBP) in the first year of policy implementation, relative to the prior year. CEP participation resulted in substantial participation gains (23 percentage points for NSLP, 13 percentage points for SBP). State policies with limited free meal expansions showed no significant effect.Conclusions and RelevanceResults of this comparative research analysis suggest that UFSM policies may effectively increase school meal participation, indicating the need for sustained state and federal support to increase participation rates and","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"29 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glucagon-Like Peptide-1 Receptor Agonist Eligibility Among US Adolescents and Young Adults.","authors":"Ashwin K Chetty,Mona Sharifi,James T Nugent","doi":"10.1001/jamapediatrics.2025.2308","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2308","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"21 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data and Analysis Concerns in Trial of Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants.","authors":"Mohamed El-Dib, Terrie Inder","doi":"10.1001/jamapediatrics.2025.1447","DOIUrl":"10.1001/jamapediatrics.2025.1447","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"925"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change to Open Access Status.","authors":"","doi":"10.1001/jamapediatrics.2025.2389","DOIUrl":"10.1001/jamapediatrics.2025.2389","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"930"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sampling and Coding Errors in Study of Distribution of Pediatric Subspecialists.","authors":"","doi":"10.1001/jamapediatrics.2025.1382","DOIUrl":"10.1001/jamapediatrics.2025.1382","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"929-930"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Error in References.","authors":"","doi":"10.1001/jamapediatrics.2025.2549","DOIUrl":"10.1001/jamapediatrics.2025.2549","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"179 8","pages":"930"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12322789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraindications to Immunization of Solid Organ Transplant Patients With Varicella Vaccine-Reply.","authors":"Amy G Feldman, Lara A Danziger-Isakov","doi":"10.1001/jamapediatrics.2025.1310","DOIUrl":"10.1001/jamapediatrics.2025.1310","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":" ","pages":"922-923"},"PeriodicalIF":18.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}