JAMA Pediatrics最新文献

{"title":"US Neonatal Mortality From Perinatal Causes.","authors":"Muzamil Khan,Waseem Nabi,Nouman Aziz,Abu Huraira Bin Gulzar,Shree Rath,Munaza Afaq,Sanjay Eda","doi":"10.1001/jamapediatrics.2025.1710","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1710","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"16 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Errors in Abstract, Introduction, Results, Discussion, and Table.","authors":"","doi":"10.1001/jamapediatrics.2025.2190","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.2190","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"640 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Centered Innovation Must Include People With Disabilities-Reply.","authors":"Dimitri A Christakis","doi":"10.1001/jamapediatrics.2025.1627","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1627","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"13 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"There Are No Sacred Deer in Science.","authors":"Dimitri A Christakis","doi":"10.1001/jamapediatrics.2025.1597","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1597","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"13 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cash Transfers and Their Effect on Maternal and Young Children's Health: A Randomized Clinical Trial.","authors":"Greg J Duncan,Katherine Magnuson,Alicia S Kunin-Batson,Hirokazu Yoshikawa,Nathan A Fox,Sarah Halpern-Meekin,Nicholas J Ainsworth,Sarah R Black,Jennifer Mize Nelson,Timothy D Nelson,Michael K Georgieff,Debra Karhson,Lisa A Gennetian,Kimberly G Noble","doi":"10.1001/jamapediatrics.2025.1612","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1612","url":null,"abstract":"ImportanceMothers and children in low-income households are more likely to experience worse mental and physical health than those from higher-income households.ObjectiveTo determine the effect of 4 years of monthly unconditional cash transfers on the mental health of mothers with low-income and the physical health of mothers and children.Design, Setting, and ParticipantsThis was a parallel-group, randomized clinical trial conducted from May 2018 to July 2023. Mother-infant dyads were recruited (May 2018-June 2019) from postpartum wards in 12 hospitals in 4 cities: Omaha, Nebraska; Minneapolis/St Paul, Minnesota; New Orleans, Louisiana; and New York, New York. Data were analyzed from September 2023 to February 2025.InterventionsMothers were randomly assigned to receive either a high-cash gift ($333 per month) or a low-cash gift ($20 per month) on debit cards. The cash gifts continued for the first 6 years of their children's lives. Data analyzed here were collected after 4 years of monthly transfers.Main Outcomes and MeasuresOutcomes were preregistered and measured around the child's fourth birthday. Maternal outcomes included depression, anxiety, and body mass index (BMI). Child outcomes included age- and sex-adjusted BMI percentile and maternal report of child health (overall health, times sick in the past year, and presence of chronic health conditions).ResultsA total of 1000 mother-infant dyads (mean [SD] maternal age, 27.0 [5.8] years) were included in this study. Among those mothers, 400 were randomly assigned to receive the $333 high-cash gift and 600 received the $20 low-cash gift on debit cards. Data were available from 891 mother-child dyads. No statistically detectable group differences were found in maternal depressive symptoms (effect size [ES], 0.04; 95% CI, -0.08 to 0.17; P = .51), anxiety (ES, 0.12; 95% CI, -0.02 to 0.25; P = .09), or BMI (ES, -0.06; 95% CI, -0.21 to 0.09; P = .42). In addition, there were no statistically detectable group differences in child BMI percentile (ES, -0.03; 95% CI, -0.17 to 0.12; P = .73) or overall child health (ES, 0.08; 95% CI, -0.07 to 0.22; P = .30).Conclusions and RelevanceMonthly unconditional cash transfers totaling approximately $15 000 over 4 years to mothers with low incomes did not improve maternal mental health, maternal or child BMI, or maternal report of children's health. These results could reflect the absence of causal connections between cash transfers and health, the possibility that impacts of early childhood income may not appear until later in life, or that an 18% increase in income is insufficient to overcome the structural vulnerabilities associated with poverty that contribute to health.Trial RegistrationClinicalTrials.gov Identifier: NCT03593356.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"6 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Will Nirsevimab Reduce the Burden on Public Health Care?-Reply.","authors":"Heidi L Moline,Meredith L McMorrow,Fatimah S Dawood","doi":"10.1001/jamapediatrics.2025.1552","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1552","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"271 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensive Nurse Home Visiting and Early Childhood Outcomes: A Randomized Clinical Trial.","authors":"Katarina Swanson,Sam Ayers,Dea Oviedo,R Annetta Zhou,Mary Ann Bates,Katherine Baicker,Alyna T Chien,Margaret McConnell","doi":"10.1001/jamapediatrics.2025.1600","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1600","url":null,"abstract":"ImportancePrograms that provide home visiting in early life have been proposed as a way to reduce early childhood adversity and improve child health outcomes. More evidence is needed to understand these programs' impact when delivered at scale.ObjectiveTo evaluate how receiving home visits through the Nurse-Family Partnership (NFP), a program designed to support young and low-income families, impacted children's utilization and health outcomes in the 2 years after birth.Design, Setting, and ParticipantsThe NFP is a home visiting program designed with the aim of reducing the incidence of adverse health outcomes in early childhood. In this study, we used data from a randomized clinical trial that enrolled 5670 Medicaid-eligible pregnant people in South Carolina who were randomly assigned at a 2:1 ratio to the NFP treatment (n = 3806) or usual care (n = 1864) between 2016 and 2020. The trial was conducted in 9 NFP-implementing authorities. Participants were eligible if they were fewer than 28 weeks pregnant with their first child, aged 15 years or older, and income eligible for Medicaid (income <200% of the federal poverty level). Data analysis was performed from June 2023 to July 2024.InterventionThe treatment group was offered NFP home visits during pregnancy and 2 years postpartum, while the control group received usual care.Main Outcomes and MeasuresThe primary outcome was a composite measure that included child mortality and claims related to major injury or concern for abuse or neglect within the first 2 years of life. Secondary outcomes included emergency department utilization and preventive health care measures, such as well-child visits and their components, including screenings for cognitive development, blood lead levels, fluoride varnish application, and dental health. We used an intent-to-treat approach with a linear regression model to estimate the treatment effect of NFP on early childhood outcomes by comparing participants assigned to the control and treatment group, regardless of whether they used NFP services.ResultsAmong enrolled participants, 4932 individuals were tracked to a live birth (3295 in the intervention group and 1637 in the control group) and were analyzed for child health and utilization outcomes once their child turned 2 years old. Mean (SD) participant age was 22.5 (4.7) years. The incidence of the composite adverse outcome was 27.3% and 26.8% in the intervention and control groups, respectively (adjusted between-group difference, 0.4 percentage points; 95% CI, -2.3 to 3.0), with no statistically significant differences between elements of the composite primary outcome. Among participants assigned to receive NFP, their children were less likely to use the emergency department by 2.9 percentage points (95% CI, -5.5 to -0.3), a 4% reduction relative to the rate of 72.8% in the control group. Once we adjusted for multiple hypothesis testing, this outcome was no longer statistically significant. Assignment to NFP did n","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"21 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paternal Perinatal Depression, Anxiety, and Stress and Child Development: A Systematic Review and Meta-Analysis.","authors":"Genevieve Le Bas,Stephanie R Aarsman,Alana Rogers,Jacqui A Macdonald,Gessica Misuraca,Sarah Khor,Elizabeth A Spry,Larissa Rossen,Emmelyn Weller,Kayla Mansour,George Youssef,Craig A Olsson,Samantha J Teague,Delyse Hutchinson","doi":"10.1001/jamapediatrics.2025.0880","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.0880","url":null,"abstract":"ImportanceThis systematic review and meta-analysis comprehensively synthesizes the extant literature on the association of paternal perinatal mental distress (ie, depression, anxiety, and stress) with offspring development from birth to adolescence.ObjectiveTo provide a meta-analytic synthesis of the literature on the association between paternal perinatal depression, anxiety, and stress and offspring development during the first 18 years of life.Data SourcesWe searched MEDLINE Complete, Embase, PsycINFO, CINAHL Complete, and the gray literature for studies published up to November 2024.Study SelectionInclusion criteria included availability in English, a human sample, quantitative data, longitudinal design, and having a measure of paternal perinatal mental distress and offspring development.Data Extraction and SynthesisOf the 9572 studies identified, 48 cohorts (from 84 studies) with 674 effect sizes met criteria for quantitative synthesis (including 286 unpublished associations sourced from doctoral theses or through contact with authors of eligible studies). Univariate random-effects models were used to quantitatively synthesize the associations between paternal perinatal mental distress and offspring development. Study quality was assessed using the US National Institutes of Health quality assessment tool for observational, cohort, and cross-sectional studies. Data analysis was completed in January 2025.Main Outcomes and MeasuresThe primary outcomes were global, social-emotional, adaptive, cognitive, language, physical, and motor development in offspring in the first 18 years of life.ResultsPaternal perinatal mental distress was associated with poorer global (r = -0.12; 95% CI, -0.22 to -0.01), social-emotional (r = 0.09; 95% CI, 0.07-0.11), cognitive (r = -0.07; 95% CI, -0.13 to -0.01), language (r = -0.15; 95% CI, -0.25 to -0.05), and physical development (r = 0.04; 95% CI, 0.00-0.08) in offspring. No evidence was found for adaptive and motor outcomes. Associations were generally stronger for postnatal than antenatal mental distress, suggesting that a father's mental state may exert a more direct influence on the developing child after birth.Conclusions and RelevanceEvidence from this systematic review and meta-analysis indicates that paternal mental distress is a potentially modifiable predictor of child development. Reducing mental distress in fathers perinatally is thus an important target for preventative interventions aiming to support fathers during the transition to parenthood and promote the health and well-being of next-generation offspring.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"43 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Income and Maternal/Child Health-The Baby's First Years Trial.","authors":"Margaret McConnell,Margaret G Parker","doi":"10.1001/jamapediatrics.2025.1594","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1594","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"26 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Will Nirsevimab Reduce the Burden on Public Health Care?","authors":"Fangrui Ding","doi":"10.1001/jamapediatrics.2025.1555","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.1555","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"37 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}