Javma-journal of The American Veterinary Medical Association最新文献

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Toward collaborative artificial intelligence development for animal well-being. 面向动物福利的协作式人工智能开发。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2025-01-10 DOI: 10.2460/javma.24.10.0650
Jennifer J Sun
{"title":"Toward collaborative artificial intelligence development for animal well-being.","authors":"Jennifer J Sun","doi":"10.2460/javma.24.10.0650","DOIUrl":"https://doi.org/10.2460/javma.24.10.0650","url":null,"abstract":"<p><p>This review focuses on opportunities and challenges of future AI developments in veterinary medicine, from the perspective of computer science researchers in developing AI systems for animal behavior analysis. We examine the paradigms of supervised learning, self-supervised learning, and foundation models, highlighting their applications and limitations in automating animal behavior analysis. These emerging technologies present future challenges in data, modeling, and evaluation in veterinary medicine. To address this, we advocate for a collaborative approach that integrates the expertise of AI researchers, veterinary professionals, and other stakeholders to navigate the evolving landscape of AI in veterinary medicine. Through cross-domain dialogue and an emphasis on human and animal well-being, we can shape AI development to advance veterinary practice for the benefit of all.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-8"},"PeriodicalIF":1.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative prophylactic antibiotics were not associated with decreased surgical site infections following hemilaminectomy in dogs: a retrospective study. 狗半椎板切除术后术后预防性抗生素与手术部位感染的减少无关:一项回顾性研究。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2025-01-10 DOI: 10.2460/javma.24.10.0677
Ericka L Jaramillo, Steven W Frederick, Sarah K Israel
{"title":"Postoperative prophylactic antibiotics were not associated with decreased surgical site infections following hemilaminectomy in dogs: a retrospective study.","authors":"Ericka L Jaramillo, Steven W Frederick, Sarah K Israel","doi":"10.2460/javma.24.10.0677","DOIUrl":"https://doi.org/10.2460/javma.24.10.0677","url":null,"abstract":"<p><strong>Objective: </strong>To compare hemilaminectomy surgical site infection (SSI) rates in dogs treated with or without postoperative prophylactic antibiotics.</p><p><strong>Methods: </strong>Medical records of 275 client-owned dogs from 1 tertiary referral hospital were retrospectively reviewed for dogs treated with thoracolumbar hemilaminectomy for intervertebral disk herniation between 2018 and 2023. Dogs were grouped according to whether they were treated with prophylactic postoperative antibiotics (group A) or not (group B). Relevant case details including dog signalment, duration of anesthetic procedure, method of incision closure, perioperative and prophylactic postoperative antibiotic prescription, and diagnosis of postoperative SSI (as defined by the CDC) were recorded. Wilson binomial CIs were calculated for SSI rates. Surgical site infection rates between dogs given or not given antibiotics were analyzed with a Fisher exact test.</p><p><strong>Results: </strong>The overall SSI rate was 3% (8 of 275; 95% CI, 1% to 6%). The SSI rate in group A was 3% (5 of 147; 95% CI, 1% to 8%), which was not statistically different from the 2% SSI rate (3 of 128; 95% CI, 1% to 7%) in group B (P = .728). There was not a statistical difference in SSI rates between closure methods (intradermal absorbable, 1% [1 of 79]; cutaneous staples, 4% [7 of 184]; cutaneous nylon, 0% [0 of 12]; P = .611).</p><p><strong>Conclusions: </strong>Overall hemilaminectomy SSI rates in this study were low, and prescription of prophylactic antibiotics was not associated with a decreased SSI rate.</p><p><strong>Clinical relevance: </strong>Practicing antimicrobial stewardship through avoidance of antimicrobial prophylaxis in clean surgical procedures may not be clinically detrimental to outcomes in hemilaminectomy dogs.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-5"},"PeriodicalIF":1.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dogs neutered prior to perineal herniorrhaphy or that develop postoperative fecal incontinence are at an increased risk for perineal hernia recurrence. 会阴疝修补术前绝育或术后大便失禁的狗会增加会阴疝复发的风险。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2025-01-08 DOI: 10.2460/javma.24.07.0487
Abigail L Hatch, Mandy L Wallace, Kenneth A Carroll, Janet A Grimes, Brian J Sutherland, Chad W Schmiedt
{"title":"Dogs neutered prior to perineal herniorrhaphy or that develop postoperative fecal incontinence are at an increased risk for perineal hernia recurrence.","authors":"Abigail L Hatch, Mandy L Wallace, Kenneth A Carroll, Janet A Grimes, Brian J Sutherland, Chad W Schmiedt","doi":"10.2460/javma.24.07.0487","DOIUrl":"https://doi.org/10.2460/javma.24.07.0487","url":null,"abstract":"<p><strong>Objective: </strong>To identify risk factors for recurrence and surgical site infection (SSI) after perineal hernia repair surgery in dogs.</p><p><strong>Methods: </strong>Medical records of male dogs undergoing perineal herniorrhaphy from 2008 to 2023 at a single institution were retrospectively reviewed. Data pertinent to patient signalment, surgical repair methods, risk factors for SSI, and risk factors for recurrence were collected. Follow-up was obtained via referring veterinarian records and/or owner interviews. Dogs without 12 months of postoperative follow-up were excluded. Statistical analysis was performed with descriptive statistics and compared between groups by use of a combination of univariable analyses.</p><p><strong>Results: </strong>84 dogs were included in this study. Recurrence occurred in 13 cases (15%), and SSIs occurred in 6 cases (7%). Dogs neutered prior to surgical correction of a perineal hernia were 4.4 times as likely to have a recurrence of the hernia after surgery compared to dogs neutered at time of surgical correction, and dogs that developed fecal incontinence postoperatively were 3.4 times as likely to have a recurrence. There were no other significant associations between perineal hernia recurrence or the development of SSIs and the associated risk factors evaluated.</p><p><strong>Conclusions: </strong>No risk factors for the development of SSI could be identified in this group. Dogs neutered prior to perineal herniorrhaphy compared to dogs neutered at time of surgical correction as well as dogs that developed fecal incontinence postoperatively may have both been at increased risk for recurrence after surgical hernia correction.</p><p><strong>Clinical relevance: </strong>Owners of dogs undergoing perineal herniorrhaphy after a prior castration should be educated on the possible increased risk of hernia recurrence postoperatively, and owners of dogs that develop fecal incontinence postoperatively should be informed of the possible increased risk for hernia recurrence.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-6"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel pleural effusion phenotype and sonographic findings of phenobarbital-induced pseudolymphoma with coagulopathic hemorrhage in a cat. 猫苯巴比妥诱导的假性淋巴瘤伴凝血性出血的新型胸腔积液表型和超声表现。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2025-01-03 DOI: 10.2460/javma.24.10.0643
Eliza K Muir, Alexandra D Gibalski, Stephen L Millar
{"title":"Novel pleural effusion phenotype and sonographic findings of phenobarbital-induced pseudolymphoma with coagulopathic hemorrhage in a cat.","authors":"Eliza K Muir, Alexandra D Gibalski, Stephen L Millar","doi":"10.2460/javma.24.10.0643","DOIUrl":"https://doi.org/10.2460/javma.24.10.0643","url":null,"abstract":"","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-3"},"PeriodicalIF":1.6,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Veterinary technicians report in a survey how futile veterinary treatments contribute to their moral distress and impact their professional and personal lives. 兽医技术人员在一项调查中报告了无效的兽医治疗如何导致他们的道德困境并影响他们的职业和个人生活。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2025-01-02 DOI: 10.2460/javma.24.10.0659
Nathan W Peterson, Kelly Foltz, Lisa Moses, J Wesley Boyd
{"title":"Veterinary technicians report in a survey how futile veterinary treatments contribute to their moral distress and impact their professional and personal lives.","authors":"Nathan W Peterson, Kelly Foltz, Lisa Moses, J Wesley Boyd","doi":"10.2460/javma.24.10.0659","DOIUrl":"https://doi.org/10.2460/javma.24.10.0659","url":null,"abstract":"<p><strong>Objective: </strong>To document veterinary technicians' (VTs') experiences with medical futility and its subsequent impact on moral distress and attrition from the profession.</p><p><strong>Methods: </strong>A cross-sectional study using a 56-question web-based, confidential and anonymous survey was distributed through the National Association of Veterinary Technicians in America between January 19 and February 15, 2023.</p><p><strong>Results: </strong>There were 1,944 responses from approximately 8,500 members (22% response rate). Nearly all respondents (97.8%) reported having encountered futile treatments during their careers, with 94.7% having provided such treatments. Most respondents (83.7%) had been asked or directed to act against their conscience to provide futile treatments to terminally ill patients, with 80.8% having done so. Providing futile treatments resulted in moderate to severe stress in 76.9% of VTs surveyed; respondents reported experiencing negative emotional (96.6%) or physical responses (83.4%) associated with medically futile treatments. Nearly half (48.7%) have considered leaving their position due to moral distress associated with providing futile treatments, and 55.5% claimed to have firsthand knowledge of someone who has left the profession for the same reason.</p><p><strong>Conclusions: </strong>Encounters with medical futility were a common occurrence among respondents. Furthermore, futile medical treatments caused a significant increase in moral stress for the VTs polled, which may contribute to professional attrition.</p><p><strong>Clinical relevance: </strong>Targeting ways to mitigate moral distress due to experiences with futility may increase retention and career satisfaction of VTs.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2024 analysis of compensation, job duties, and benefits among US shelter medicine veterinarians. 美国收容所兽医的薪酬、工作职责和福利分析。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2024-12-26 DOI: 10.2460/javma.24.10.0639
Rachael E Kreisler, Miranda E Spindel, Mark Rishniw
{"title":"2024 analysis of compensation, job duties, and benefits among US shelter medicine veterinarians.","authors":"Rachael E Kreisler, Miranda E Spindel, Mark Rishniw","doi":"10.2460/javma.24.10.0639","DOIUrl":"https://doi.org/10.2460/javma.24.10.0639","url":null,"abstract":"<p><strong>Objective: </strong>To understand the salary, benefits, hours, and job duties of shelter medicine veterinarians.</p><p><strong>Methods: </strong>Similar to a 2018 survey, an anonymous survey on compensation and duties of shelter medicine veterinarians was conducted via a commercial platform from January 4 to 31, 2024. The survey was distributed through social media, message boards, and specialty listservs. Participants were categorized into part-time clinical veterinarians, full-time clinical veterinarians, academic faculty, and leadership/consultants.</p><p><strong>Results: </strong>299 US shelter veterinarians responded: 258 were engaged in clinical work (198 working full time and 60 part time), 18 worked in academia, and 23 held leadership/consulting roles. Full-time clinical veterinarians reported a median salary of $122,500, reflecting a 25% increase since 2018. Part-time clinicians earned $85/h-a 77% increase-while working a median of 24 h/wk. Faculty had a median salary of $130,000, a 20% increase. Those in leadership or consulting roles earned a median of $168,000, a 40% increase.</p><p><strong>Conclusions: </strong>Salaries increased across all categories, with the highest increase for leadership/consulting roles and the lowest for academic positions. Part-time veterinarians saw a large rise in hourly rates, while working fewer hours. Leadership positions yielded the highest incomes, followed by faculty. Clinical salaries were 5% lower than the AVMA-reported 2022 salaries for private practice veterinarians and 7% lower for companion animal veterinarians.</p><p><strong>Clinical relevance: </strong>Understanding these compensation trends assists shelter veterinarians in making informed career decisions and negotiations. Despite salary increases, shelter veterinarians' earnings remain lower than those in private practice.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective evaluation of outpatient intravenous ketamine-lidocaine infusions for the palliation of cancer pain in dogs and cats. 门诊静脉注射氯胺酮-利多卡因缓解犬猫癌性疼痛的回顾性评价。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2024-12-26 DOI: 10.2460/javma.24.09.0595
Kari E Iocolano, Andrea Looney, Cheryl E Balkman, Kelly R Hume, Jordyn M Boesch, Skylar R Sylvester
{"title":"Retrospective evaluation of outpatient intravenous ketamine-lidocaine infusions for the palliation of cancer pain in dogs and cats.","authors":"Kari E Iocolano, Andrea Looney, Cheryl E Balkman, Kelly R Hume, Jordyn M Boesch, Skylar R Sylvester","doi":"10.2460/javma.24.09.0595","DOIUrl":"https://doi.org/10.2460/javma.24.09.0595","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical benefit and adverse events following outpatient intravenous (IV) ketamine-lidocaine (KL) infusions for palliation of cancer pain in dogs and cats.</p><p><strong>Methods: </strong>Medical records from 15 years (2008 to 2023) were searched and data reviewed retrospectively. Animals were prescribed ketamine (0.15 mg/kg/h) and lidocaine (3 mg/kg/h in dogs and 1.5 mg/kg/h in cats) diluted in 250 mL (cats or dogs < 15 kg) or 500 mL (dogs ≥ 15 kg) of 0.9% saline administered IV at 2.5 mL/kg/h for 4 to 6 hours.</p><p><strong>Results: </strong>A total of 105 dogs and 9 cats (114 animals) were included. The most common tumor types treated were appendicular osteosarcoma in dogs (n = 45 [43%]) and oral squamous cell carcinoma in cats (4 [44%]). All animals received concomitant oral analgesic medications. Animals received a median of 2 KL infusions (range, 2 to 49 KL infusions). The overall clinical benefit rate was 76% following the first KL infusion, as defined by an improvement in at least 1 evaluated clinical sign. The likelihood of clinical response was improved with a ketamine infusion rate ≥ 2 µg/kg/min, total ketamine dose of ≥ 0.5 mg/kg, and lidocaine infusion rate ≥ 25 µg/kg/min.</p><p><strong>Conclusions: </strong>Outpatient IV KL infusions were well-tolerated in dogs and cats with cancer and provided a high rate of clinical benefit when combined with standard anti-cancer and analgesic therapies.</p><p><strong>Clinical relevance: </strong>Management of cancer pain often requires multimodal analgesia. Given the clinical benefit and minimal toxicity observed with outpatient KL infusions, KL infusions should be considered as an adjunctive treatment to use in combination with anticancer therapy, oral and topical analgesics, and interventional therapies in dogs and cats for palliation of refractory cancer pain from advanced disease.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-8"},"PeriodicalIF":1.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperthyroid cats that develop azotemia following successful radioiodine treatment have shorter survival times compared to cats that remain nonazotemic. 放射性碘治疗成功后出现氮质血症的甲亢猫的生存时间比未发生氮质血症的猫短。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2024-12-26 DOI: 10.2460/javma.24.10.0653
Mark E Peterson, Stephanie Carmody, Mark Rishniw
{"title":"Hyperthyroid cats that develop azotemia following successful radioiodine treatment have shorter survival times compared to cats that remain nonazotemic.","authors":"Mark E Peterson, Stephanie Carmody, Mark Rishniw","doi":"10.2460/javma.24.10.0653","DOIUrl":"https://doi.org/10.2460/javma.24.10.0653","url":null,"abstract":"<p><strong>Objective: </strong>Many hyperthyroid cats (15% to 50%) have concurrent chronic kidney disease (CKD) that is \"masked\" and will not become azotemic until after treatment. Previous studies reported that mild-to-moderate azotemic CKD after methimazole or thyroidectomy does not adversely affect survival. Our objective was to determine whether hyperthyroid cats with masked CKD rendered euthyroid with radioiodine (131I) have shorter survival than 131I-treated euthyroid cats that remain nonazotemic.</p><p><strong>Methods: </strong>We treated 1,047 hyperthyroid cats with 131I from 2013 to 2020 to render them euthyroid, as defined by normal serum concentrations of thyroxine and thyroid-stimulating hormone. Cats were subsequently classified as azotemic or nonazotemic at 6 to 12 months after 131I treatment (median, 6.1 months). Cats were then monitored at 6- to 12-month intervals (ie, complete physical examination, routine laboratory testing, and serum thyroid hormone concentrations) until death or end of study period (January 2024). Survival time was defined as the period from the date of 131I treatment to the date of death or last follow-up.</p><p><strong>Results: </strong>After 131I treatment to restore euthyroidism, 128 of 1,047 (12%) cats developed azotemia, whereas 919 remained nonazotemic. Azotemic cats had a shorter median survival time than nonazotemic cats (2.8 vs 4.3 years).</p><p><strong>Conclusions: </strong>In contrast to earlier studies that reported no shortening of survival in cats with mild-to-moderate azotemic CKD after treatment, our results show that euthyroid cats developing azotemia after 131I treatment have shorter survival, with median survival lessened by 1.5 years.</p><p><strong>Clinical relevance: </strong>Recognizing concurrent CKD in hyperthyroid cats is crucial, as it shortens survival and enables clinicians to tailor treatment for affected hyperthyroid cats.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-6"},"PeriodicalIF":1.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapy with clopidogrel or rivaroxaban has equivalent impacts on recurrence of thromboembolism and survival in cats following cardiogenic thromboembolism: the SUPERCAT study. SUPERCAT研究:氯吡格雷或利伐沙班治疗对心源性血栓栓塞后猫血栓栓塞复发和生存的影响相当。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2024-12-18 DOI: 10.2460/javma.24.09.0584
Benjamin M Brainard, Amanda E Coleman, Anne Kurosawa, John E Rush, Daniel F Hogan, Marjory B Brooks, Marc S Kraus
{"title":"Therapy with clopidogrel or rivaroxaban has equivalent impacts on recurrence of thromboembolism and survival in cats following cardiogenic thromboembolism: the SUPERCAT study.","authors":"Benjamin M Brainard, Amanda E Coleman, Anne Kurosawa, John E Rush, Daniel F Hogan, Marjory B Brooks, Marc S Kraus","doi":"10.2460/javma.24.09.0584","DOIUrl":"https://doi.org/10.2460/javma.24.09.0584","url":null,"abstract":"<p><strong>Objective: </strong>To assess the impact of clopidogrel or rivaroxaban administration on recurrence of arterial thromboembolism (ATE) in cats that have recovered from cardiogenic ATE.</p><p><strong>Methods: </strong>This multicenter prospective double-masked protocol enrolled 45 cats that had recovered from cardiogenic ATE and were randomized to receive either clopidogrel (18.75 mg/cat, PO; n = 19) or rivaroxaban (2.5 mg/cat, PO; 26) as sole anticoagulant therapy for up to 2 years after the initial ATE. Primary outcome measures included recurrent ATE or death from any cause. In addition to bimonthly internet-based surveys of animal quality of life, echocardiograms were performed by veterinary cardiologists at 2, 6, 12, and 18 months after initial ATE.</p><p><strong>Results: </strong>17 cats experienced ATE recurrence: 7 of 19 (37%) in the clopidogrel group and 10 of 26 (39%) in the rivaroxaban group. Three cats in each group survived for the entire 2-year study without recurrence. In the clopidogrel group, median (95% CI) time to ATE recurrence was 663 days (150 to not calculable) and in the rivaroxaban group, 513 days (242 to not calculable). Median time from enrollment to death from cardiac or noncardiac causes was also not different between treatment groups.</p><p><strong>Conclusions: </strong>Single-agent antithrombotic therapy with rivaroxaban in cats recovered from cardiogenic embolism delayed recurrence of ATE for a similar time period as single-agent therapy with clopidogrel.</p><p><strong>Clinical relevance: </strong>In cats that have recovered from cardiogenic ATE, either rivaroxaban or clopidogrel may be used for single-agent thromboprophylaxis to delay ATE recurrence.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distal teat amputation for distal papillary canal injuries in lactating dairy cows. 泌乳奶牛远端乳头管损伤的远端乳头截肢。
IF 1.6 2区 农林科学
Javma-journal of The American Veterinary Medical Association Pub Date : 2024-12-13 Print Date: 2025-02-01 DOI: 10.2460/javma.24.05.0313
Cassandra A Klostermann, Marie Babkine, André Desrochers, Hélène Lardé, Sylvain Nichols
{"title":"Distal teat amputation for distal papillary canal injuries in lactating dairy cows.","authors":"Cassandra A Klostermann, Marie Babkine, André Desrochers, Hélène Lardé, Sylvain Nichols","doi":"10.2460/javma.24.05.0313","DOIUrl":"10.2460/javma.24.05.0313","url":null,"abstract":"<p><strong>Objective: </strong>The objectives were to describe a distal teat amputation and determine the long-term outcomes in dairy cows.</p><p><strong>Methods: </strong>This retrospective study examined medical records of 22 lactating dairy cows admitted to the Farm Animal Hospital from 2015 to 2021 for distal teat and papillary canal injuries that received a distal teat amputation as the sole surgical treatment. Long-term follow-up was obtained from the Canadian Dairy Network (CDN) and milk producers to determine whether the cows remained in the herd and identify whether any factors affected this outcome.</p><p><strong>Results: </strong>The hindquarters were affected in 18 of the 22 distally amputated teats (82%; 95% CI, 66% to 98%). Mastitis was the most common postoperative complication. Of the 22 cows, CDN and follow-up information was available for 18 cows (82%). Of these 18 cows, 13 (72%; 95% CI, 51% to 93%) remained in the herd for at least the start of a subsequent lactation following surgery.</p><p><strong>Conclusions: </strong>Lactating dairy cows had a favorable chance of remaining in the herd following a distal teat amputation.</p><p><strong>Clinical relevance: </strong>Decreased milking efficiency caused by distal teat injuries can be a source of economic loss for the milk producer. Distal teat amputation to reestablish milk flow was a practical procedure that required attentive postoperative care.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"199-207"},"PeriodicalIF":1.6,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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