Iranian Journal of Medical Physics最新文献_第9页

Comparison of Treatment Planning Parameters of Different Radiotherapy Techniques for Craniospinal Irradiation 不同放疗技术对颅脊柱放射治疗方案参数的比较

Iranian Journal of Medical Physics Pub Date : 2020-06-17 DOI: 10.22038/IJMP.2020.45574.1712

B. Goswami, R. Jain, Suresh Yadav, Sunil Kumar, S. Oommen, S. Manocha, Ganesh Krishnarao Jadav

{"title":"Comparison of Treatment Planning Parameters of Different Radiotherapy Techniques for Craniospinal Irradiation","authors":"B. Goswami, R. Jain, Suresh Yadav, Sunil Kumar, S. Oommen, S. Manocha, Ganesh Krishnarao Jadav","doi":"10.22038/IJMP.2020.45574.1712","DOIUrl":"https://doi.org/10.22038/IJMP.2020.45574.1712","url":null,"abstract":"Aim: The purpose of this study is to compare linear accelerator-based three-dimensional conformal radiotherapy (Linac-3DCRT) technique with different techniques of the Radixact-X9 for the treatment of craniospinal irradiation (CSI).Materials and Methods: Retrospectively, twenty-two CSI patients (Medulloblastoma) which have previously planned and treated with Linac-3DCRT using Novalis-Tx unit are selected for analysis. For each patient plan, additional sets of plans are generated using Helical, Direct-3DCRT, and Direct-intensity-modulated radiotherapy (Direct-IMRT) techniques of the Radixact-X9 unit. The dose prescription for brain planning target volume (brain PTV) and spine PTV are 36 Gy in 20 fractions and kept the same for all techniques. Planning time, patient setup time, homogeneity index (HI), and different dose-volume parameters for both PTV and organs at risk (OARs) are evaluated for comparison.Results: The Radixact-X9-Helical technique plans are able to achieve the lowest possible maximum and minimum doses for most of the organs. The Radixact-X9-Helical technique gives better PTV homogeneity in comparison with Linac-3DCRT, Radixact-X9-Direct-3DCRT, and Radixact-X9-Direct-IMRT. The values of HI are 3.57±0.77, 17.37±1.44, 8.15±1.02 and 8.62±0.98 respectively.Conclusion: The Radixact-X9-Helical treatment technique is easier to use and able to generate a better homogeneous plan in comparison to other treatment techniques like 3DCRT and IMRT in respect of different parameters for comparison like dose-volume received by OARs, patient setup time, move isocenter and many more. So it can be an integral part of the radiotherapy department where patients required it, according to their clinical needs like shorter treatment time with good sparing of critical OARs.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44397213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of 6MV and 10MV flattened and flattening filter free beam in whole brain radiotherapy – A treatment planning study. 6MV和10MV扁平化和扁平化无滤波器光束在全脑放射治疗中的影响——一项治疗计划研究。

Iranian Journal of Medical Physics Pub Date : 2020-06-05 DOI: 10.22038/IJMP.2020.46947.1740

Tamilarsu Suresh, Saminathan Madeswaran

引用次数: 0

Suitability of chambers in relative dose measurement of small fields for accelerated photon delivered from medical linear accelerator 腔在医用线性加速器发射的加速光子的小场相对剂量测量中的适用性

Iranian Journal of Medical Physics Pub Date : 2020-05-18 DOI: 10.22038/IJMP.2020.46202.1721

Santunu Purohit, A. Meaze, SM Enamul Kabir, Md. Shakilur Rahman, Md. Kawchar Ahmed Patwary

引用次数: 0

IS THE 28-DAY RULE SAFE FOR USE IN ABDOMINAL RADIOGRAPHY? 在腹部x线摄影中使用28天是安全的吗?

Iranian Journal of Medical Physics Pub Date : 2020-05-18 DOI: 10.22038/IJMP.2020.46280.1723

S. Moey, Norfariha Che Mohamed, Nursyahirah Saidin

{"title":"IS THE 28-DAY RULE SAFE FOR USE IN ABDOMINAL RADIOGRAPHY?","authors":"S. Moey, Norfariha Che Mohamed, Nursyahirah Saidin","doi":"10.22038/IJMP.2020.46280.1723","DOIUrl":"https://doi.org/10.22038/IJMP.2020.46280.1723","url":null,"abstract":"Introduction: The 28-day rule is utilized as a precautionary measure for irradiating the fetus at an early stage of conception for abdominal and pelvic radiography. There is a probability of the women being pregnant if the 28-day rule is applied for this examination and thus irradiating the conceptus. It is difficult to convince people that low radiation doses during early pregnancy will not cause any harm to the conceptus. As such this study was to ascertain whether the 28-day rule can be used safely for abdominal radiography in women of reproductive age. Materials and Methods: The experimental study was conducted at the Radiography Laboratory, International Islamic University Malaysia, Kuantan using an anthropomorphic PBU-50 phantom. The entrance surface dose (ESD), organ dose and effective dose (ED) were estimated using CALDose_X 5.0 software, based on the exposure parameters and tube output of the x-ray unit. Results: The mean ESD for AP abdominal radiographic examination of 3.162 mGy is within that recommended by radiation protection regulatory bodies. Additionally, the mean organ dose of 0.468 mGy is lower than the threshold value of 100 mSv for the “all-or-none” phenomenon to happen. Further, the mean ED of 0.73 mSv is within the recommendation of the International Atomic Energy Agency (IAEA) and the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). Conclusion: This study indicated that the 28-day rule is safe to be used for abdominal radiography for a woman of reproductive age.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42729789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Effects of Curcumin and Lycopene Treatment on Human Lymphocytes before 2 and 6 Gy of 6 MV X-Ray Irradiation 姜黄素和番茄红素在6MV X射线照射2和6Gy前对人淋巴细胞影响的评价

Iranian Journal of Medical Physics Pub Date : 2020-05-18 DOI: 10.22038/IJMP.2020.44248.1676

R. Fardid, Hossein Fazilatpour, Narges Ebrahimi, A. Sadeghi, T. Zare

{"title":"Evaluation of the Effects of Curcumin and Lycopene Treatment on Human Lymphocytes before 2 and 6 Gy of 6 MV X-Ray Irradiation","authors":"R. Fardid, Hossein Fazilatpour, Narges Ebrahimi, A. Sadeghi, T. Zare","doi":"10.22038/IJMP.2020.44248.1676","DOIUrl":"https://doi.org/10.22038/IJMP.2020.44248.1676","url":null,"abstract":"Introduction: Today, the use of ionizing radiation in medicine has grown as an important tool for diagnosis and treatment of diseases. However, the harmful effects of radiation should be also considered. Some substances such as lycopene and curcumin can reduce or increase the harmful effects of radiation on humans. So the aim of this study was to evaluate the radioprotective effects of lycopene and curcumin based on the MN assay. Material and Methods: In this study, the effects of lycopene and curcumin on reducing or increasing the harmful effects of radiation were studied using the micronucleus assay. The effects of lycopene (5 μg/mL) and curcumin (5 μg/mL) were evaluated at radiation doses of 2 and 6 Gy. Results: The results indicated that the simultaneous use of curcumin and lycopene can be radioprotective at low radiation doses (2 Gy; p 0.05). Conclusion: Based on the present results, further research using other methods may contribute to our understanding of the effect of simultaneous use of curcumin and lycopene at low and high doses of X-ray radiation.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":"18 1","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44834439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of in-house head CTDI phantoms based on polyester-resin materials 基于聚酯树脂材料的内部头部CTDI模型的开发

Iranian Journal of Medical Physics Pub Date : 2020-05-14 DOI: 10.22038/IJMP.2020.46387.1728

R. Asiah, H. Sutanto, C. Anam, Z. Arifin, B. Bahrudin, Rumaisya Hilmawati

{"title":"Development of in-house head CTDI phantoms based on polyester-resin materials","authors":"R. Asiah, H. Sutanto, C. Anam, Z. Arifin, B. Bahrudin, Rumaisya Hilmawati","doi":"10.22038/IJMP.2020.46387.1728","DOIUrl":"https://doi.org/10.22038/IJMP.2020.46387.1728","url":null,"abstract":"Introduction: CTDI phantoms are used to optimize computed tomography examinations in terms of X-ray image quality and received dose. In this regard, the aim of this study is to develop low price head CTDI phantoms from the polyester-resin (PESR) materials as an alternative phantom.Material and Methods: The PESR was mixed with methyl ethyl ketone peroxide (MEKP) as catalysts. The ratios between catalyst and PESR were 1:150, 1:200, 1:250, and 1:300. The dimensions of the alternative phantoms were designed similar to the standard CTDI phantom, i.e. the length was 15 cm, diameter was 16 cm, and it had 5 holes with a diameter of 1.31 cm. The measured CTDIs using the PESR-MEKP phantoms were compared to those measured using the standard polymethyl methacrylate (PMMA) phantom. The CTDI measurements were carried out using the CT dose profiler and a Philips Brilliance CT 16 slice with a tube voltage and tube loading of 120 kVp and 200 mAs, respectively. Results: The results showed that the values of CTDIs of the PESR-MEKP phantoms are slightly greater (up to 6%) than the standard PMMA phantom. It was found that the CTDI measured using the PESR-MEKP phantom with a ratio of 1:300 has the smallest difference compared to the results of standard PMMA phantom. In addition, in that ratio, the phantom is the most homogeneous.Conclusion: The head CTDI phantoms based on PESR-MEKP have been developed and evaluated. It is found that the PR-MEKP phantom with a ratio of 1:300 has an insignificant difference compared to the standard PMMA phantom. The phantom is constructed easily with more reasonable cost compared to the standard phantom. It might be useful for the CT centers which do not have access to the standard PMMA phantom for dose measurements.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48918547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Amorphous Silicon (ASi) Electronic Portal Imaging Devices for Other applications for Linear Accelerator Quality Assurance 非晶硅(ASi)电子传送门成像装置在其他直线加速器质量保证应用中的应用

Iranian Journal of Medical Physics Pub Date : 2020-05-14 DOI: 10.22038/IJMP.2020.45434.1701

A. El-Taher, Gena Mohamed, K. Shahat, Mahmoud Salem

{"title":"Use of Amorphous Silicon (ASi) Electronic Portal Imaging Devices for Other applications for Linear Accelerator Quality Assurance","authors":"A. El-Taher, Gena Mohamed, K. Shahat, Mahmoud Salem","doi":"10.22038/IJMP.2020.45434.1701","DOIUrl":"https://doi.org/10.22038/IJMP.2020.45434.1701","url":null,"abstract":"The success of radiation therapy depends critically on the accuracy of patient alignment in treatment position day after day. Electronic portal imaging devices (EPIDs) are widely used to monitor patient position during daily radiotherapy sessions. To verify other applications for medical linear accelerator quality assurance (linac QA), images of a 10×10 cm² and 18×18 cm² open field were acquired. The EPID was positioned at a fixed detector distance of 150 cm. The wedge profile and wedge factors with high level of accuracy were demonstrated. The profiles acquired using EPID deviated in shape and magnitude by up to 16% from the ion chamber profiles. The use of EPID for linac QA could be simplified by improving the available software analysis tools, thus making it more efficient. The study showed that the EPID aSi500 has the potential to be used as a relative dosimeter, making it a very simple and efficient tool for daily QA. All EPID measurements were performed using the linear accelerator model Varian DMX. The physical characteristics measured in this work suggest that the SLIC-EPID can be an efficient tool for daily QA.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":"18 1","pages":"285-292"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42453518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of various radiotherapy techniques in breast cancer with inclusion of internal mammary nodes by through thermoluminescent dosimetry inside the RANDO phantom RANDO体模内热释光剂量测定法对癌症合并乳内结的不同放射治疗技术的比较

Iranian Journal of Medical Physics Pub Date : 2020-05-14 DOI: 10.22038/IJMP.2020.44901.1693

M. T. B. Toosi, Shokouhozaman Soleymanifard, Ashraf Farkhari, F. H. Shandiz, E. Salari

{"title":"Comparison of various radiotherapy techniques in breast cancer with inclusion of internal mammary nodes by through thermoluminescent dosimetry inside the RANDO phantom","authors":"M. T. B. Toosi, Shokouhozaman Soleymanifard, Ashraf Farkhari, F. H. Shandiz, E. Salari","doi":"10.22038/IJMP.2020.44901.1693","DOIUrl":"https://doi.org/10.22038/IJMP.2020.44901.1693","url":null,"abstract":"Introduction: In the various techniques of breast cancer radiotherapy, the presence of the internal mammary nodes (IMNs) in the target volume is important to select the most appropriate technique. This study aimed to compare three radiotherapy techniques with the inclusion of IMNs regarding the dose homogeneity index (DHI) of regional lymph nodes, chest wall, and the dose received by the heart and left lung.Material and Methods: Three techniques were planned on the CT images of the RANDO phantom including wide tangent (WT) contained two opposed tangential 6 MV photon beams, oblique parasternal photon (OPP) and oblique parasternal electron (OPE) that included two opposed tangential 6 MV photon beams with an anterior oblique 6 MV photon beam and an anterior oblique 15 MeV electron beam added to two tangential beams, respectively. The doses reached to the contoured organs were compared in three techniques by using data gathered from the thermoluminescent dosimetry and treatment planning system.Results: The OPE technique caused a lower absorbed dose for the left IMNs than the other two techniques. For the OPP technique, the dose received by the left lung was higher than the tolerance, and the lung dose in the OPE is slightly lower than the WT technique. The absorbed dose by the heart was lowest for the WT technique and the DHI for this technique was better than the other two techniques.Conclusion: The WT technique showed better results regarding the IMNs and chest wall dose homogeneity distribution and the organ at risk protection.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46182885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of cancer by radiotherapy and nanoparticles coupled with Methotrexate drug 甲氨蝶呤与纳米颗粒联合放疗治疗癌症

Iranian Journal of Medical Physics Pub Date : 2020-05-14 DOI: 10.22038/IJMP.2020.47108.1747

Sahar E. Abo-Neima, A. Ismail, H. A. Motaweh

{"title":"Treatment of cancer by radiotherapy and nanoparticles coupled with Methotrexate drug","authors":"Sahar E. Abo-Neima, A. Ismail, H. A. Motaweh","doi":"10.22038/IJMP.2020.47108.1747","DOIUrl":"https://doi.org/10.22038/IJMP.2020.47108.1747","url":null,"abstract":"Introduction: Cancer patients will receive Radiation therapy (RT) as part of their treatment as monotherapy or as part of a combination treatment. RT uses high-energy radiation such as photons and strong ions. Nanoparticles (NPs) are used for magnetic hyperthermia which increases the efficacy of RT and generates heat to kill cancer cells by destroying their DNA. Materials and Methods: NPs were prepared through the co-precipitation method and characterized using TEM, SEM, and X-ray diffractometer. 56 male mice were housed under the same environmental conditions. The animals injected into the right flank with 0.25mL from 106cells/mL Ehrlich tumor suspension. When tumors reach between 5-10mm in diameter, mice will be randomly divided into eight groups as follow,1stgroup: used as negative control group injected with 25μL phosphate buffer saline without treatment,2ndgroup:injected with Fe3O4-NPs,3rdgroup: injected with Fe2O3-NPs,4thgroup: injected with Methotrexate drug (MXT),5thgroup: injected with MXT, Fe3O4 and Fe2O3-NPs,6thgroup: as 5thgroup with microwave hyperthermia,7thgroup:as 5thgroup then treated with high energy photons and 8thgroup: as 5thgroup and exposed to electron beam therapy. Tumor volume and weight were measured after 15days.Tumor apoptosis was studied using histopathology and the tumor's side effects on biological systems were investigated. Results: The results indicate that the magnetic hyperthermia application is suitable for cancer treatment with microwave and linear accelerator treatment coupled with drugs. A significant decrease in tumor size, tumor necrosis and fibrosis were observed. Conclusion: It was found that Fe3O4 and Fe2O3-NPs coupled with MXT and exposed to electron beam therapy and microwave irradiation is the best method for cancer treatment.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47672107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Comparing IDREAM as an Iterative Reconstruction Algorithm against In Filtered Back Projection in Computed Tomography IDREAM迭代重建算法与计算机层析成像中的滤波反投影算法的比较

Iranian Journal of Medical Physics Pub Date : 2020-05-01 DOI: 10.22038/IJMP.2019.41872.1613

Eslam Maamoun

{"title":"Comparing IDREAM as an Iterative Reconstruction Algorithm against In Filtered Back Projection in Computed Tomography","authors":"Eslam Maamoun","doi":"10.22038/IJMP.2019.41872.1613","DOIUrl":"https://doi.org/10.22038/IJMP.2019.41872.1613","url":null,"abstract":"Introduction: Recent studies of Computed Tomography (CT) conducted on patient dose reduction have recommended using an iterative reconstruction algorithm and mA (mili-Ampere) dose modulation. The current study aimed to evaluate Iterative Dose Reduction Algorithm (IDREAM) as an iterative reconstruction algorithm. \u0000Material and Methods: Two CT protocols (i.e., A: 120 KV /150 mA, FBP; B: 120KV/ (20-150) mAs, IDREAM) to scan water and acrylic phantoms. A number of 40 patients were assigned to two CT protocols (C: n=20, 120KV/160 ±10 mAs, FBP and D: n=20, 120 KV/ (30-150 mAs, IDREAM), the two groups (C and D) were then referred to abdomen and pelvis CT scan (Sinovision, insitum 16) with contrast. Image quality parameters, dose calculations were measured for all groups (i.e., A, B, C, and D). \u0000Results: Group B had a highly significant SNR with less significant noise (P 0.05) in acrylic phantom, as compared to group A. CTDIvol (A: 13.94 mGy ; B: 6.91 mGy , P<0.05 ) and DLP (A:501.76 mGy.cm ; B :248.88 mGy.cm). Noise and SNR were significantly different (P<0.05) in group D against C. CTDIvol (C: 30.3±5.2 mGy ; D : 15.4 ±2.7 mGy, P<0.05 ) , DLP (C:544±100 mGy.cm; D :272.3±50.3 mGy.cm ,P<0.05) and the effective dose (C:8.1±1.5 mSv; D :4.08±0.75 mSv,P<0.05) \u0000Conclusion: The results of the present study were indicative of the feasibility of IDREAMas an iterative reconstruction algorithm.","PeriodicalId":14613,"journal":{"name":"Iranian Journal of Medical Physics","volume":"17 1","pages":"170-174"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45164280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0