Japanese journal of infectious diseases最新文献_第4页

Prediction of Prognosis in Patients with Severe Fever with Thrombocytopenia Syndrome. 预测严重发热伴血小板减少综合征患者的预后。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-23 Epub Date: 2024-09-30 DOI: 10.7883/yoken.JJID.2024.015

Yi Zhang, Lingtong Huang, Zheyue Shu, Wei Wu, Hongliu Cai, Yu Shi

{"title":"Prediction of Prognosis in Patients with Severe Fever with Thrombocytopenia Syndrome.","authors":"Yi Zhang, Lingtong Huang, Zheyue Shu, Wei Wu, Hongliu Cai, Yu Shi","doi":"10.7883/yoken.JJID.2024.015","DOIUrl":"10.7883/yoken.JJID.2024.015","url":null,"abstract":"This study aimed to understand the clinical characteristics of severe fever with thrombocytopenia syndrome (SFTS) and identify the risk factors for prognosis. In this retrospective study, we collected epidemiological, demographic, clinical, and laboratory data from 101 patients with SFTS. Patients were divided into survival and deceased groups, and a logistic regression model was used to evaluate the association between the predictors and prognostic variables. A joint detection factor model was constructed, and a receiver operating characteristic curve was drawn. A nomogram was established using the R language, and its efficiency in diagnosing SFTS was evaluated using a calibration curve. Patients in the deceased group were more likely to be older, have a shorter hospitalization stay, and have renal and multiple organ failure than those in the survival group. Statistically significant differences were observed in the neutrophil percentage, lymphocyte percentage, neutrophil-to-lymphocyte ratio, platelet (PLT) count, aspartate aminotransferase (AST)/alanine transaminase (ALT) ratio, AST, blood urea nitrogen, lactate dehydrogenase, hydroxybutyrate dehydrogenase, thromboplastin time, and activated partial thromboplastin time between the two groups. Lymphocyte percentage, PLT count, and the AST/ALT ratio were independent risk factors for mortality in patients with SFTS. Thus, we established a prediction model for SFTS mortality with good efficiency.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"28-34"},"PeriodicalIF":1.3,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fatal Septic Shock Due to Dolosigranulum pigrum Bacteremia: a Case Report. 猪多糖菌血症导致的脓毒性休克和死亡：病例报告。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-23 Epub Date: 2024-10-31 DOI: 10.7883/yoken.JJID.2024.178

Sachiko Hakoda, Akira Ishiwata, Ryo Shimada, Shuji Hatakeyama, Makoto Kondo

引用次数: 0

Contents. 内容。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-01 DOI: 10.7883/yoken.JJID.2025.78.2.contents

引用次数: 0

Contents. 内容。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-01 DOI: 10.7883/yoken.JJID.2025.78.1.contents

引用次数: 0

Comparison of viral load in the nasopharyngeal swabs of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different epidemic seasons in Gunma prefecture, Japan. 日本群马县不同流行季节SARS-CoV-2患者鼻咽拭子病毒载量比较

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-12-27 DOI: 10.7883/yoken.JJID.2024.301

Yuki Nakazawa, Hiroyuki Tsukagoshi, Ryo Shimada, Rina Kubota, Nobuhiro Saruki

{"title":"Comparison of viral load in the nasopharyngeal swabs of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different epidemic seasons in Gunma prefecture, Japan.","authors":"Yuki Nakazawa, Hiroyuki Tsukagoshi, Ryo Shimada, Rina Kubota, Nobuhiro Saruki","doi":"10.7883/yoken.JJID.2024.301","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.301","url":null,"abstract":"The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has repeatedly undergone mutations since its emergence, based on which it has been assumed that there was a change in its characteristic, including virulence or antigenicity. In this study, we investigated the viral load in the nasopharyngeal samples of patients with SARS-CoV-2 in Gunma prefecture, Japan, from April 2, 2020, to April 1, 2023. The amount of virus in samples in the Omicron-variant-prevalent period was higher than that of strains detected in samples before week 50 of 2020, the B.1.1.284-prevalent period, the Alpha-variant-prevalent period, and the Delta-variant- prevalent period. Moreover, among Omicron variants, the sublineage BA.5-prevalent period showed higher amount of virus in the samples than BA.1-prevalent period and BA.2-prevalent period. Hence, the new variant may have been able to release more viruses into the nasopharyngeal samples during the process of repeated mutations, resulting in widespread infection. The amount of virus detected in the nasopharyngeal samples showed an increasing tendency with the evolution of the virus. Therefore, considering that the amount of virus in specimens is also vital factor contributing to the spread of infection, it is important to examine this factor in samples.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of host vertebrate DNA in tick species collected from vegetation in Fukuoka, Japan. 日本福冈地区植被蜱类宿主脊椎动物DNA检测。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-12-27 DOI: 10.7883/yoken.JJID.2024.170

Takayuki Kobayashi, Yuki Ashizuka

引用次数: 0

Molecular detection of Mycobacterium leprae using RLEP-LAMP and restriction enzyme to ensure amplification specificity. 使用 RLEP-LAMP 和限制性酶对麻风分枝杆菌进行分子检测，以确保扩增特异性。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-12-27 DOI: 10.7883/yoken.JJID.2024.251

Mukul Sharma, Purna Dwivedi, Srishti Tripathi, Purushottam Patel, Pushpendra Singh

引用次数: 0

Long-term management of refractory vaginal trichomoniasis following initial metronidazole treatment failure: A case series. 甲硝唑治疗失败后难治性阴道滴虫病的长期治疗：一个病例系列。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-12-27 DOI: 10.7883/yoken.JJID.2024.255

Taketomo Maruki, Masahiro Ishikane, Masami Kurokawa, Taketo Kubo, Yusuke Miyazato, Norio Ohmagari

{"title":"Long-term management of refractory vaginal trichomoniasis following initial metronidazole treatment failure: A case series.","authors":"Taketomo Maruki, Masahiro Ishikane, Masami Kurokawa, Taketo Kubo, Yusuke Miyazato, Norio Ohmagari","doi":"10.7883/yoken.JJID.2024.255","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.255","url":null,"abstract":"Guidelines for sexually transmitted infections recommend oral metronidazole (MNZ) as the first-line treatment option for vaginal trichomoniasis; however, there have been cases of prolonged symptoms or recurrence after treatment. To consider appropriate treatment strategies for refractory vaginal trichomoniasis, we conducted a retrospective cohort study. We reviewed the medical records of patients who tested positive for Trichomonas vaginalis (T. vaginalis) at the National Center for Global Health and Medicine between August 2011 and May 2023. Refractory vaginal trichomoniasis was defined as the failure after the initial MNZ treatment. During the study period, nine cases of vaginal trichomoniasis were identified, six of which were refractory to treatment for T. vaginalis. Four patients were cured with a combination of oral and vaginal tinidazole (TNZ) therapy, one with oral TNZ and one with two doses of MNZ. Possible causes of treatment failure include MNZ-resistant T. vaginalis, reinfection between partners, and infections of other sexual transmitted diseases. However, the fact that TNZ was effective suggests that MNZ-resistant T. vaginalis may have been the cause. Although MNZ resistance testing was not performed in this study, treatment with TNZ should be considered in cases of refractory vaginal trichomoniasis, possibly caused by MNZ-resistant T. vaginalis.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Streptococcal Toxic Shock Syndrome Caused by a Streptococcus pyogenes emm22 Genotype with a CsrS Mutation: a Case Report. 化脓性链球菌emm22基因型伴有CsrS突变的STSS：病例报告。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-11-21 Epub Date: 2024-02-29 DOI: 10.7883/yoken.JJID.2023.332

Kaoru Ogawa, Jiro Kamiyama, Tadayoshi Ikebe, Shigemasa Taguchi, Kazuya Kiyota

{"title":"Streptococcal Toxic Shock Syndrome Caused by a Streptococcus pyogenes emm22 Genotype with a CsrS Mutation: a Case Report.","authors":"Kaoru Ogawa, Jiro Kamiyama, Tadayoshi Ikebe, Shigemasa Taguchi, Kazuya Kiyota","doi":"10.7883/yoken.JJID.2023.332","DOIUrl":"10.7883/yoken.JJID.2023.332","url":null,"abstract":"A previously healthy 22-year-old woman was admitted to our hospital after an out-of-hospital cardiac arrest. Spontaneous circulation was restored prior to arrival at the hospital. However, the patient's vital signs remained unstable. Vasopressors and hyperhydration therapy were administered. Computed tomography did not reveal a cause of the cardiac arrest. Antibiotics were initiated after obtaining blood culture samples. The patient was admitted to the intensive care unit (ICU). High-dose vasopressors and hyperhydration therapy were continued and fresh frozen plasma was transfused. Two hours after ICU admission, gram staining of a blood smear revealed the presence of Streptococcus, and the antibiotics were switched to penicillin G potassium and clindamycin, and immunoglobulins were administered. Extracorporeal membrane oxygenation was initiated 10 h after ICU admission owing to respiratory failure caused by fluid overload; however, the patient's condition did not improve and she died 40 h after admission. Blood culture results confirmed the presence of Streptococcus pyogenes; the T and M serotypes were unclassifiable. The emm genotype was emm22. Sequencing revealed the presence of streptococcal pyrogenic toxin genes, speA and speB, whereas speC was absent. CsrS, CsrR, and Rgg amino acid sequencing revealed the presence of a CsrS mutation.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"348-352"},"PeriodicalIF":1.3,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139990069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of the Proinflammatory Cytokine Profile during Acute SARS-CoV-2 Infection in People with Human Immunodeficiency Virus. 人类免疫缺陷病毒感染者急性 SARS-CoV-2 感染期间促炎细胞因子的特征。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-11-21 Epub Date: 2024-06-28 DOI: 10.7883/yoken.JJID.2024.184

Alitzel Anzurez, Lucky Runtuwene, Thi Thu Thao Dang, Kaori Nakayama-Hosoya, Michiko Koga, Yukihiro Yoshimura, Hiroaki Sasaki, Nobuyuki Miyata, Kazuhito Miyazaki, Yoshimasa Takahashi, Tadaki Suzuki, Hiroshi Yotsuyanagi, Natsuo Tachikawa, Tetsuro Matano, Ai Kawana-Tachikawa

{"title":"Characterization of the Proinflammatory Cytokine Profile during Acute SARS-CoV-2 Infection in People with Human Immunodeficiency Virus.","authors":"Alitzel Anzurez, Lucky Runtuwene, Thi Thu Thao Dang, Kaori Nakayama-Hosoya, Michiko Koga, Yukihiro Yoshimura, Hiroaki Sasaki, Nobuyuki Miyata, Kazuhito Miyazaki, Yoshimasa Takahashi, Tadaki Suzuki, Hiroshi Yotsuyanagi, Natsuo Tachikawa, Tetsuro Matano, Ai Kawana-Tachikawa","doi":"10.7883/yoken.JJID.2024.184","DOIUrl":"10.7883/yoken.JJID.2024.184","url":null,"abstract":"Persistent inflammation during chronic human immunodeficiency virus (HIV) infection may affect the immune response against severe acute respiratory syndrome-coronavirus 2 (SARS- CoV-2) infection. Plasma levels of multiple proinflammatory cytokines during acute SARS-CoV-2 infection were measured in people with HIV (PWH) with effective combination antiretroviral therapy. There were no significant differences in any of the measured cytokines between severity levels of coronavirus disease 2019 (COVID-19) in PWH, while most were significantly higher in HIV-uninfected individuals with severe COVID-19, suggesting that excess cytokines release by hyperinflammatory responses do not occur in individuals with severe COVID-19 with HIV infection. The strong associations between the cytokines observed in HIV-uninfected individuals, particularly between IFN-α/TNF-α and other cytokines, were lost in PWH. The steady-state plasma levels of IP-10, ICAM-1, and CD62E were significantly higher in PWH, indicating that they were in an enhanced inflammatory state. The absence of several inter-cytokine correlations was observed in in vitro lipopolysaccharide stimulus-driven cytokine production in PWH. These data suggest that inflammatory responses during SARS-CoV-2 infection in PWH are distinct from those in HIV-uninfected individuals, partially because of the underlying inflammatory state and/or impairment of innate immune cells.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"301-310"},"PeriodicalIF":1.3,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0