Irbm最新文献

{"title":"Leveraging Action Unit Derivatives for Early-Stage Parkinson's Disease Detection","authors":"Anas Filali Razzouki ,&nbsp;Laetitia Jeancolas ,&nbsp;Graziella Mangone ,&nbsp;Sara Sambin ,&nbsp;Alizé Chalançon ,&nbsp;Manon Gomes ,&nbsp;Stéphane Lehéricy ,&nbsp;Jean-Christophe Corvol ,&nbsp;Marie Vidailhet ,&nbsp;Isabelle Arnulf ,&nbsp;Dijana Petrovska-Delacrétaz ,&nbsp;Mounim A. El-Yacoubi","doi":"10.1016/j.irbm.2024.100874","DOIUrl":"10.1016/j.irbm.2024.100874","url":null,"abstract":"<div><h3>Objective</h3><div>Hypomimia is a symptom of Parkinson's disease (PD), involving a decrease in facial movements and a loss of emotional expressions on the face. The objective of this study is to identify hypomimia in individuals in the early stage of PD by analyzing facial action units (AUs).</div></div><div><h3>Methods</h3><div>Our study included video recordings from 109 PD subjects and 45 healthy control (HC) subjects with an average of two videos per person (294 videos in total). The participants were requested to perform rapid syllable repetitions. For the purpose of discriminating between normal facial muscle movements and those specific to PD subjects experiencing hypomimia, we calculate the derivatives of the AUs. We derive global features based on the AUs intensities and their derivatives, and utilize XGBoost and Random Forest to perform the classification between PD and HC.</div></div><div><h3>Results</h3><div>We achieve subject-level classification scores of up to 73.7% for balanced accuracy (BA) and an area under the curve (AUC) of 81.39% using XGBoost, and a BA of 79.1% and an AUC of 83.7% with Random Forest. These findings show potential in identifying hypomimia during the early phases of PD. Moreover, this research could facilitate the continuous monitoring of hypomimia beyond hospital settings, enabled by telemedicine.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100874"},"PeriodicalIF":5.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Performance of Blueback Physio® Medical Device in the Management of Patients Suffering from Chronic Low Back Pain: Randomized Clinical Trial","authors":"Ines Moudjari ,&nbsp;Caroline Pautard ,&nbsp;Clément Jouanneau ,&nbsp;Anne-gaëlle Servel ,&nbsp;Philippe Le Cavorzin ,&nbsp;Benjamin Margo ,&nbsp;Ophélie Flageul ,&nbsp;Gwenvael Le Guicher ,&nbsp;Régine Le Bouquin Jeannès","doi":"10.1016/j.irbm.2024.100875","DOIUrl":"10.1016/j.irbm.2024.100875","url":null,"abstract":"<div><h3>Background</h3><div>Chronic low back pain (CLBP) is one of the leading causes of disability in the world population. In 2017, in central Europe and North America, prevalence of CLBP was 12.51% and 9.80% respectively. The rehabilitation of the abdominal muscles, and notably the deep transversus abdominis, plays an important role in the management of CLBP in physiotherapy.</div></div><div><h3>Objectives</h3><div>The main objective of this study is to prove that a biofeedback device of the transversus abdominis, named Blueback Physio<span><math><msup><mrow></mrow><mrow><mi>®</mi></mrow></msup></math></span>, developed by the Blueback company, improves the management of patients suffering from this pain.</div></div><div><h3>Design</h3><div>The clinical trial is designed as a prospective, monocentric, comparative, open-label randomized and parallel group study.</div></div><div><h3>Method</h3><div>41 subjects were included in this study and divided into two groups, one control group, in which the subjects used the device without visual biofeedback, and one intervention group, where the subjects used the complete biofeedback. The study included patients cared in day or full hospitalization in FSEF Rennes-Beaulieu Clinic, France, as part of the PRESDO program (“programme de prévention secondaire des dorso-lombalgies”).</div></div><div><h3>Results</h3><div>We found that patients who use visual biofeedback of the transverse abdominis muscle are more likely to (i) quickly learn to voluntarily contract this muscle and (ii) have better control of this muscle compared to patients who do not use it. Finally, the PRESDO program improves overall patient well-being.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100875"},"PeriodicalIF":5.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The R-Vessel-X Project","authors":"Abir Affane ,&nbsp;Mohamed A. Chetoui ,&nbsp;Jonas Lamy ,&nbsp;Guillaume Lienemann ,&nbsp;Raphaël Peron ,&nbsp;Pierre Beaurepaire ,&nbsp;Guillaume Dollé ,&nbsp;Marie-Ange Lebre ,&nbsp;Benoît Magnin ,&nbsp;Odyssée Merveille ,&nbsp;Mathilde Morvan ,&nbsp;Phuc Ngo ,&nbsp;Thibault Pelletier ,&nbsp;Hugo Rositi ,&nbsp;Stéphanie Salmon ,&nbsp;Julien Finet ,&nbsp;Bertrand Kerautret ,&nbsp;Nicolas Passat ,&nbsp;Antoine Vacavant","doi":"10.1016/j.irbm.2025.100876","DOIUrl":"10.1016/j.irbm.2025.100876","url":null,"abstract":"<div><div><strong>1) Objectives:</strong> This technical report presents a synthetic summary and the principal outcomes of the project R-Vessel-X (“Robust vascular network extraction and understanding within hepatic biomedical images”) funded by the French <em>Agence Nationale de la Recherche</em>, and developed between 2019 and 2023. <strong>2) Material and methods:</strong> We used datasets and tools publicly available such as IRCAD, Bullitt or VascuSynth to obtain real or synthetic angiographic images. The main contributions lie in the field of 3D angiographic image analysis: filtering, segmentation, modeling and simulation, with a specific focus on the liver. <strong>3) Results:</strong> We paid a particular attention to open-source software diffusion of the developed methods, by means of 3D Slicer plugins for the liver anatomy segmentation (SlicerRVXLiverSegmentation) and vesselness filtering (SlicerRVXVesselnessFilters), and an online demo for the generation of synthetic and realistic vessels in 2D and 3D (OpenCCO). <strong>4) Conclusion:</strong> The R-Vessel-X project provided extensive research outcomes, covering various topics related to 3D angiographic image analysis, such as filtering, segmentation, modeling and simulation. We also developed open-source and free softwares so that the research communities in biomedical engineering can use these results in their future research.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100876"},"PeriodicalIF":5.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical Effects of Osteoporosis on the Sacroiliac Joint After Lumbosacral Fusion Surgery","authors":"Wei Fan ,&nbsp;Chao Wang ,&nbsp;Sheng-Nan Liu ,&nbsp;Yu Zhang ,&nbsp;Ming Zhang ,&nbsp;Li-Xin Guo","doi":"10.1016/j.irbm.2025.100877","DOIUrl":"10.1016/j.irbm.2025.100877","url":null,"abstract":"<div><h3>Objective</h3><div>Lumbar/lumbosacral fusion is a common surgical approach for treating lumbar degenerative disc disease, a condition that disproportionately affects a large portion of elderly population. Osteoporosis, another age-related disease, is also prevalent among the elderly. Previous studies have elucidated the biomechanical effects of osteoporosis on the postoperative lumbar spine. However, little attention has been paid to adjacent sacroiliac joints (SIJs), and it remains unclear whether or how osteoporosis impacts the SIJ biomechanics. The aim of this study was to determine the effects of osteoporosis on the range of motion (ROM) and stress distribution within the SIJs following lumbosacral fusion, and to identify potential implications for postoperative outcomes.</div></div><div><h3>Methods</h3><div>The previously validated, normal human lumbo-pelvic finite-element model was used to simulate the interbody fusion procedures at L5–S1, and an osteoporotic condition was simulated by reducing bone mechanical properties in the model. The ROM and stress distribution within the left and right SIJs were compared between the surgical models with and without osteoporosis in flexion, extension, lateral bending, and axial rotation motions.</div></div><div><h3>Results</h3><div>The presence of osteoporosis led to a significant increase in SIJ ROM: 38.9% and 36.5% in flexion, 19.5% and 15.9% in extension, 33.3% and 40.0% in lateral bending, and 26.38% and 20.0% in axial rotation, respectively, for left and right SIJs. Moreover, higher stress concentrations were observed at the SIJs in the osteoporotic model.</div></div><div><h3>Conclusion</h3><div>Osteoporosis exacerbates the SIJ motion and stress after lumbosacral fusion, indicating a potential increased risk of SIJ instability and degeneration among affected patients. The findings underscore the importance of considering osteoporosis in preoperative planning and postoperative management strategies for lumbosacral fusion procedures.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 2","pages":"Article 100877"},"PeriodicalIF":5.6,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of Near-Infrared Optical Techniques for Non-invasive Blood Glucose Measurement: A Pilot Study","authors":"Sameera Fathimal M. ,&nbsp;Janardanan Subramonia Kumar ,&nbsp;Jeya Prabha A. ,&nbsp;Jothiraj Selvaraj ,&nbsp;Fabiola Jemmie Shilparani F. ,&nbsp;Angeline Kirubha S.P.","doi":"10.1016/j.irbm.2024.100870","DOIUrl":"10.1016/j.irbm.2024.100870","url":null,"abstract":"<div><h3>Background</h3><div>Diabetes mellitus manifested by escalated blood glucose, demands periodic or continuous glucose monitoring in the pursuit of improved control, optimal management, and appropriate medication. The existing state-of-the-art for blood glucose estimation are invasive methodologies necessitating the acquisition of blood sample through either a finger-stick or venipuncture.</div></div><div><h3>Methods</h3><div>We propose a dual Near-infrared wavelength integrated in a 3D printed enclosure as the optical prototype for non-invasive glucose estimation. We acquired data from both diabetic and healthy subjects with the developed system and subsequently validated the system.</div></div><div><h3>Results</h3><div>The system demonstrated commendable clinical accuracy, as evidenced by the alignment of data pairs representing actual blood glucose levels and blood glucose levels predicted by our optical system within the A+B zones of the Parkes error grid and zones of no-risk and lower risk as defined by the surveillance error grid. We achieved compliant pairs percentage of 95.6%, which satisfies the accuracy requirements of the blood glucose monitoring surveillance study. The mean absolute percentage error attained with the proposed device (5.99%) was significant in predicting the blood glucose.</div></div><div><h3>Conclusion</h3><div>We successfully deployed the NIR wavelengths functionality as the promising approach for glucose monitoring, offering new possibilities for improved medical interventions.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100870"},"PeriodicalIF":5.6,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Automatic Detection of Severely and Mildly Infected COVID-19 Patients with Supervised Machine Learning Models” [IRBM (2023) 100725]","authors":"Mehmet Tahir Huyut","doi":"10.1016/j.irbm.2024.100869","DOIUrl":"10.1016/j.irbm.2024.100869","url":null,"abstract":"","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 6","pages":"Article 100869"},"PeriodicalIF":5.6,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Review of Feature Extraction Techniques for sEMG Signal Classification: From Handcrafted Features to Deep Learning Approaches","authors":"Sidi Mohamed Sid'El Moctar,&nbsp;Imad Rida,&nbsp;Sofiane Boudaoud","doi":"10.1016/j.irbm.2024.100866","DOIUrl":"10.1016/j.irbm.2024.100866","url":null,"abstract":"<div><div>Surface Electromyography (sEMG) has become an essential tool in various fields, including prosthetic control and clinical evaluation of the neuromusculoskeletal system. In recent years, the application of machine learning and deep learning techniques to sEMG signal classification has gained significant interest. This survey provides a detailed exploration of feature extraction methods for sEMG classification, from traditional handcrafted features to learned features.</div></div><div><h3>Objectives</h3><div>This review aims to provide a comprehensive overview of feature extraction techniques for sEMG signal classification, focusing on both handcrafted and learned features. It seeks to advance research by offering a deeper understanding of fundamental concepts in sEMG signal analysis, along with comparisons and summaries of state-of-the-art approaches.</div></div><div><h3>Materials and Methods</h3><div>The survey covers various feature extraction techniques used for sEMG classification, including signal acquisition, preprocessing, and the application of conventional machine learning and deep learning classifiers. It offers taxonomies, definitions, and performance comparisons, equipping researchers with a broad understanding of current methodologies.</div></div><div><h3>Results</h3><div>Handcrafted features combined with traditional machine learning classifiers have demonstrated strong performance, especially with smaller datasets. However, deep learning techniques have shown superior results in many applications, despite challenges related to data availability and model interpretability. The survey highlights key findings regarding the performance of both approaches.</div></div><div><h3>Conclusion</h3><div>This study bridges the gap between traditional and learned feature extraction techniques for sEMG signal classification. It provides a valuable resource for researchers and practitioners, offering insights that can guide future advancements. Key areas for future research include addressing data scarcity in deep learning and improving model interpretability for clinical applications.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 6","pages":"Article 100866"},"PeriodicalIF":5.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Skeletal Muscle Immobilization on Regional Anisotropic Viscohyperelastic Properties Change in a Rat Model","authors":"Clément Simon,&nbsp;Sonia Rekik,&nbsp;Mustapha Zidi","doi":"10.1016/j.irbm.2024.100868","DOIUrl":"10.1016/j.irbm.2024.100868","url":null,"abstract":"<div><h3>Objectives</h3><div>The passive mechanical properties of immobilized skeletal muscle in short position were investigated over time. The purpose of this study was to explore in three different zones (distal, proximal and medial) of the biceps brachii immobilized of rats in short position and its free contralateral.</div></div><div><h3>Material and methods</h3><div>In vitro equibiaxial relaxation tests were performed from samples harvested from immobilized skeletal muscles of rats during one or two weeks. Material parameters were identified by using a viscohyperelastic model described by an anisotropic strain energy function coupled with second order Maxwell's model.</div></div><div><h3>Results</h3><div>The excising zone of samples greatly influenced the parameters of the hyperelastic behavior while the immobilization had effects on the viscoelasticity response instead. Based on measurements of histological parameters from flexor carpi ulnaris muscles, the immobilization produced contractile tissue atrophy and connective tissue thickening. A correlation between mechanical and structural characteristics was given. The histological analysis permitted to quantify fibrosis in the immobilized skeletal muscle and to correlate with the mechanical behavior change.</div></div><div><h3>Conclusion</h3><div>The immobilization of skeletal muscles in short position is highly deleterious. Immobilized rats displayed marked atrophy of skeletal muscle, fibrosis of the extracellular matrix and a tendency to visco-hyperelastic parameter changes. This work has the potential to be useful for future research on neuromuscular diseases like spastic myopathy which leads to muscular immobilization.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100868"},"PeriodicalIF":5.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142707202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-Time Accuracy Evaluation of Arterial Catheter Transducer Systems","authors":"Carole Lavault ,&nbsp;Lisa Guigue ,&nbsp;Daniel Anglade ,&nbsp;Francis Grimbert ,&nbsp;Yves Lavault ,&nbsp;François Boucher ,&nbsp;Norbert Noury","doi":"10.1016/j.irbm.2024.100867","DOIUrl":"10.1016/j.irbm.2024.100867","url":null,"abstract":"<div><h3>Introduction</h3><div>Arterial pressure is currently monitored in ICU with a catheter–transducer fluid line. This fluid filled tubing line distorts the original waveform due to its dynamic characteristics (natural frequency, Fn, and damping coefficient, z), introducing potentially significant errors when calculating the cardiac output from pulse contour signal analysis.</div></div><div><h3>Methods</h3><div>In our study, we cross-compared Fn and z obtained with our new Fast External Pressure Test (FEPT) and with the Fast Flush Test (FFLT), to the reference technique (Sine wave variable Frequency Analysis Test - SFAT). It was carried on a testbench for 48 hours. Fn and z were measured using the three techniques with two fluid-filled tubing lines (standard, STD, and blood conserving device, BCD).</div></div><div><h3>Results</h3><div>Fn measurements with FEPT and FFLT present similar biases (0.79 vs 0.83 Hz), but lower variability for FEPT, with limits of agreement (LOA) ranging from −3.35 to +4.99 Hz for FFLT vs −2.29 to +3.86 Hz (<span><math><mi>p</mi><mo>&lt;</mo><mn>0.0001</mn></math></span>) for FEPT. For the measurement of z, FEPT has a bias of 0.047 and LOA of −0.063 to +0.157, much lower (<span><math><mi>p</mi><mo>&lt;</mo><mn>0.0001</mn></math></span>) than those measured with the FFLT (bias 0.139 and LOA −0.028 to +0.306).</div></div><div><h3>Conclusion</h3><div>When automated, the FEPT method will detect potential situations of over/under estimations occurrences. This will prevent false alarms, alarm fatigue and therefore consequences on patient care. Eventually, FEPT turns to be more accurate than FFLT, less scattered, less time-consuming, less invasive and so well suited for use in clinical settings.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"46 1","pages":"Article 100867"},"PeriodicalIF":5.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Work and Metabolic Cost of Walking with Knee-Foot Prostheses: A Study with a Prosthesis Simulator","authors":"Aurore Bonnet-Lebrun ,&nbsp;Lucas Sedran ,&nbsp;Cécile Heidsieck ,&nbsp;Marie Thomas-Pohl ,&nbsp;Hélène Pillet ,&nbsp;Xavier Bonnet","doi":"10.1016/j.irbm.2024.100863","DOIUrl":"10.1016/j.irbm.2024.100863","url":null,"abstract":"<div><h3>Background</h3><div>At equivalent speeds, above-knee amputee subjects have a higher metabolic cost than non-amputees. Following amputation, the ankle propulsion is reduced, and using other joints to compensate is mechanically less efficient.</div></div><div><h3>Objective</h3><div>This study investigated the link between mechanical work and metabolic cost in abled-bodied subjects using a prosthesis simulator, and the influence of foot energy restitution by comparing a foot with restitution to one without.</div></div><div><h3>Method</h3><div>Six volunteers fitted with an orthosis immobilising their ankle and knee, enabling the use of a prosthesis, carried out a gait analysis and an analysis of metabolic cost. The total lower limb mechanical work and works at the hip, knee and ankle were computed.</div></div><div><h3>Results</h3><div>With an almost twofold increase, metabolic cost and hip work were significantly higher in both configurations with prosthesis than without (p &lt; 0.001 for both variables in both configurations), while total lower limb mechanical work showed no significant difference between configurations. No significant difference was observed between the two prosthetic feet in terms of metabolic cost nor mechanical work performed by the subject.</div></div><div><h3>Discussion</h3><div>Total lower limb mechanical work alone cannot explain the extra metabolic cost in subjects fitted with a knee-foot prosthesis simulator; internal inefficiencies exist. We also found that metabolic cost and hip work increase and decrease simultaneously, thus studying hip muscles work could be interesting. With no significant difference between the two feet, optimising ankle propulsion seems to be ineffective in improving metabolic cost. These findings should be evaluated in a sample of above-knee amputee subjects.</div></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 6","pages":"Article 100863"},"PeriodicalIF":5.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}