基于病例的模拟以支持复杂的主动导管:初步结果

IF 5.6 4区 医学 Q1 ENGINEERING, BIOMEDICAL
Irbm Pub Date : 2025-04-10 DOI:10.1016/j.irbm.2025.100890
Arif Badrou , Aurélien de Turenne , Nathan Lescanne , Jérôme Szewczyk , Raphaël Blanc , Nahiène Hamila , Nicolas Tardif , Aline Bel-Brunon , Pascal Haigron
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引用次数: 0

摘要

目的主动导管用于复杂解剖结构的血管内导航。然而,它们的配置和利用是具有挑战性的。有限元(FE)建模可以在早期阶段考虑主动导丝与导管的导航,以确定最佳参数并支持医生的计划和程序。然而,有限元模拟需要大量的计算时间。我们引入了基于病例的模拟(CBS)的概念,以便为复杂的导管场景快速找到适当的配置参数。方法将基于实例的推理与有限元仿真相结合,采用CBS方法重用前人仿真中的设计参数和导航参数。一个案例基础是成功的导管模拟执行参考主动脉几何形状。对于新患者,基于统计形状模型的距离度量用于从先前模拟的病例中确定适当的导管参数。这种方法的概念证明是在从主动脉弓到左颈动脉的导航中进行的。在11例患者特异性主动脉弓中,选择3例作为左颈动脉钩的参考有限元模拟,构成病例库,选择另外3例进行评价。结果检索的参数允许在100%的测试用例中成功模拟导航。这表明,所提出的方法可以有效和即时地确定适当的设计和导航参数的复杂的导管场景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Case-Based Simulation to Support Complex Active Catheterization: Preliminary Results

Case-Based Simulation to Support Complex Active Catheterization: Preliminary Results

Objective

Active catheters are intended to support endovascular navigation in complex anatomies. Nevertheless, their configuration and utilization are challenging. Finite element (FE) modeling representing the navigation of active guidewires alongside catheters can be considered at an early stage to identify the best parameters and support physicians in their planning and procedure. However, FE simulations require significant computation time. We introduce the concept of case-based simulation (CBS) to quickly find adequate configuration parameters for complex catheterization scenarios.

Method

Combining case-based reasoning and FE simulation, CBS approach is considered to reuse design and navigation parameters from previous simulations. A case base is made of successful catheterization simulations performed on reference aorta geometries. For a new patient, a distance metric based on a statistical shape model is used to determine appropriate catheterization parameters from previously simulated cases. The proof-of-concept of this method is performed in the case of the navigation from the aortic arch to the left carotid artery. Among 11 patient-specific aortic arches, three were selected for the reference FE simulations of the left carotid artery hooking to constitute the case base and three others were selected for evaluation.

Results

The retrieved parameters allowed a successful simulated navigation in 100% of the test cases. This demonstrates that the proposed approach can effectively and instantaneously determine appropriate design and navigation parameters for complex catheterization scenarios.
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来源期刊
Irbm
Irbm ENGINEERING, BIOMEDICAL-
CiteScore
10.30
自引率
4.20%
发文量
81
审稿时长
57 days
期刊介绍: IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux). As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in: -Physiological and Biological Signal processing (EEG, MEG, ECG…)- Medical Image processing- Biomechanics- Biomaterials- Medical Physics- Biophysics- Physiological and Biological Sensors- Information technologies in healthcare- Disability research- Computational physiology- …
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