IOSR Journal of Pharmacy and Biological Sciences最新文献_第3页

Isolation and Partial Characterisation of Bacteriocin Produced By Lactobacillus Fermentum 发酵乳杆菌产细菌素的分离及部分特性研究

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1204013844

K. Selvi, R. Kanthamani

引用次数: 0

Diversity of Ethno Medician Plant in Dist. Balod (C.G) 巴罗德地区少数民族药用植物多样性研究

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1203078089

Deepak Gupta, S. Gupta

{"title":"Diversity of Ethno Medician Plant in Dist. Balod (C.G)","authors":"Deepak Gupta, S. Gupta","doi":"10.9790/3008-1203078089","DOIUrl":"https://doi.org/10.9790/3008-1203078089","url":null,"abstract":"Ethno-botanical study on traditional medicinal plants was conducted in Balod district of Chattisgarh, India and documented different types of traditional medicinal plants used by the indigenous peoples. The study was focused on identifying medicinal plants with botanical name, family, local name, Habit, parts used, methods of preparation, administration and ailments treated are provided. Baiga, Gond and Oraon are common tribal communities of Balod district and completely or partially dependent on forest product for their survival and livelihood. The data was collected using interview and questionnaires by selecting 16 healers using purposive sampling method. A total number of 166 species of plants belonging to155 genera and 75 families have been recorded in study area of Balod. Total number of species, genera and families of both cultivated and wild category was studied. The present study highlights on traditional knowledge and ethno-medicinal observation in different areas of district Balod CG. The ethno medicinal information of tribal’s peoples was collected from of the study sites and brief description of the plants will be discussed later. Key-Words: Medicinal; Ethno-botany; Balod; Tribes","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"11 1","pages":"80-89"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89409583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Protease Production from Immobilized Bacillus Subtilis and Its Application 固定化枯草芽孢杆菌生产蛋白酶及其应用

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1204013437

Dr.K. Jagathy

引用次数: 0

Evolution of Reovirus in Cancer Therapy 呼肠孤病毒在癌症治疗中的进化

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1204010614

B. Jayaprakash, Sivapriya Veeraiyan, S. Gunaseelan, Y. Purushothaman

{"title":"Evolution of Reovirus in Cancer Therapy","authors":"B. Jayaprakash, Sivapriya Veeraiyan, S. Gunaseelan, Y. Purushothaman","doi":"10.9790/3008-1204010614","DOIUrl":"https://doi.org/10.9790/3008-1204010614","url":null,"abstract":"The overactive Ras signaling can ultimately lead to cancer. The 3 Ras genes in humans (HRas, KRas, and NRas) are the most common oncogenes in human cancer.Mutations that permanently activate Ras are found in 20% to 25% of all human tumors and up to 90% in certain types of cancer (e.g., pancreatic cancer). For this reason, Ras inhibitors are being studied as a treatment for cancer and other diseases with Ras overexpression. Reovirus was noted to be a potential cancer therapeutic when studies suggested it reproduces well in certain cancer cell lines. It replicates specifically in cells that have an activated Ras pathway (a cellular signaling pathway that is involved in cell growth and differentiation).Reovirus replicates in and eventually kills Ras-activated tumour cells and as cell death occurs, progeny virus particles are free to infect surrounding cancer cells. This cycle of infection, replication and cell death is believed to be repeated until all tumour cells carrying an activated Ras pathway are destroyed.Reovirus, a double-stranded ribonucleic acid virus and benign human pathogen, preferentially infects and kills cancer cells in its unmodified form, and is one of the leading oncolytic viruses currently undergoing clinical trials internationally. Importantly, reovirus has been shown to be effective as a monotherapy, as well as in combination with other anticancer options, including radiation and chemotherapeutic agents, such as gemcitabine, docetaxel, paclitaxel, and carboplatin.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"17 1","pages":"06-14"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87767435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review On In Vitro Propagation and Phytochemical Analysis of Ethnobotanically Important Orchid Crepidium Acuminatum (D.Don) Szlach. 民族植物学上重要的Crepidium Acuminatum (D.Don) Szlach离体繁殖研究进展及植物化学分析。

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1203071420

M. Arora, Satnam Singh, A. Mahajan, J. Sembi

引用次数: 1

Male Aphrodisic Screening of Plants Mucuna Prurita, Mesua Ferrea, Punica Granatum on Rats 白粘、铁花、石榴等植物对大鼠雄性催情作用的筛选

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1204011527

Sonu Sharma, A. Sharma

{"title":"Male Aphrodisic Screening of Plants Mucuna Prurita, Mesua Ferrea, Punica Granatum on Rats","authors":"Sonu Sharma, A. Sharma","doi":"10.9790/3008-1204011527","DOIUrl":"https://doi.org/10.9790/3008-1204011527","url":null,"abstract":"s: India has a rich culture of medicinal herbs and spices, including Ayurvedic, Unani, Siddha and other traditional medicines but only very few have been studied chemically and pharmacologically for their potential medicinal value. According to the World Health Organization, most populations still rely on traditional medicines for their psychological and physical health requirements. Herbal medicines are in great demand in both developed and developing countries as a source of primary health care owing to their attributes having wide biological and medicinal activities, high safety margins and lesser costs. As far as population growth is concerned India will be the leading country within few years of time span. Current pandemic population explosion demands an immediate betterment of new potential contraception. Thus, there is growing need to look for aphrodisiac more from natural plant or herbal origin as opposed to synthetic compounds which are known to cause severe unwanted side effects. In this regard, we have taken the plants Mucunaprurita, Mesuaferrea, punicagranatumthat has been used traditionally as antifertility agent in women and aphrodisiac, so that the couples without issue may be benefited for better acceptance in society and they may have better psychological health. In these plants so many secondary metabolites are present i.e carbohydrates, glycocides, alkaloids, tannins, phytosteroletc.All these three plants have pharmacological activity like Astringent, anthelimentic, nervine tonic, aphrodisiac, diuretic, vermifuge and stimulant, anodyne, antidotal, psychedelic, leucorrhea, spermatorrhea, facial paralysis and powerfully aphrodisiac, leprosy, scabies, skin diseases, pruritus, haemorrids, ulcers, depsia, impotency, leucorrhoea, haemoptysis, cephalalgia, fever and cardiac debility.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"19 1","pages":"15-27"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89527302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Comparitive Study on Outdoor and Indoor Forensic Insects encountered on Rabbit Corpses in Upper Egypt 上埃及地区兔尸室内外法医昆虫的比较研究

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1203074154

M. Aly, khaled. M. Osman, F. Galal, Gihan H. M. Ali

{"title":"Comparitive Study on Outdoor and Indoor Forensic Insects encountered on Rabbit Corpses in Upper Egypt","authors":"M. Aly, khaled. M. Osman, F. Galal, Gihan H. M. Ali","doi":"10.9790/3008-1203074154","DOIUrl":"https://doi.org/10.9790/3008-1203074154","url":null,"abstract":"This work aims to illustrate the forensic insects, their succession patterns and decomposition stages of rabbit corpses in ecologically different sites. The present study was performed on two sites including outdoor, open or roof site, in addition to indoor, closed or ground site of the faculty of science in Qena city for four successive seasons. Results showed eighteen species of necrophagous, necrophilous, omnivorous and accidental insects, of them, five outdoor species, three indoor species and ten common species. The five corpse decomposition stages (fresh, bloating, active, advanced and dry stages) have been observed. Twelve species of Diptera and three species of Coleoptera and Hymenoptera were collected from the carcasses. The dipteran species were the predominant groups on the corpses, whereas the coleopterans occupied the 2 nd . The most important forensic insects were represented by Sarcophaga carnaria, Wohlfahrtia magnifica, Chrysomya albiceps, Lucilia cuprina, Muscina stabulans, Megaselia scalaris and genus Nasonia. Moreover, the studied calliphorid and sarcophagid flies were the first colonizers to arrive and breed on rabbit carcasses. The rate of corpse decomposition was faster in summer and spring as compared to winter and autumn. Outdoor corpses decomposed faster than indoor corpses. On the other hand, the statistical analysis showed negative temperature and humidity correlation on Sarcophaga carnaria, while both Wohlfahrtia magnifica and Muscina stabulans were affected positively by temperature and humidity, respectively. Therefore, these results are recommended to be taken in Criminal investigations.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"52 1","pages":"41-54"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86927586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Anti diabetic activity of the stem bark extract and fractions of Faidherbia albida Del. (Mimosaceae) in murine model 花仙子茎皮提取物及部位抗糖尿病活性的研究。(含羞虫科)小鼠模型

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1204022630

A. J. Kashimawo, J. Kolawole, J. Kemelayefa

{"title":"Anti diabetic activity of the stem bark extract and fractions of Faidherbia albida Del. (Mimosaceae) in murine model","authors":"A. J. Kashimawo, J. Kolawole, J. Kemelayefa","doi":"10.9790/3008-1204022630","DOIUrl":"https://doi.org/10.9790/3008-1204022630","url":null,"abstract":"Background: In our continued search for potent anti-diabetic compound(s) from plants and natural sources, we tested crude extract and fractions of the stem bark of Faidherbia albida a plant traditional used in the management of diabetes mellitus in Northern Nigeria, on alloxan induced diabetic rats to obtain the most active fraction. Space and Duration of Study: The study was conducted between November 2016-March 2017 using laboratories of Departments of Pharmaceutical Chemistry and Department of Pharmacology of Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State, Nigeria. Methodology: Twenty five rats weighing between 150-200g were made diabetic with alloxan injected peritonialy. They were divided into five groups of five rats each. A sixth group of five normal fats were used for the study. They were treated with F.albida crude extract and fractions as follows; Group 1-crude extract 200mg/kg, Group 2ethylacetate fraction 50mg/kg, Group 3Butanol fraction 50mg/kg, Group 4Glibenclamide 5mg/ kg, Group 5untreated diabetic rats, Group 6Normal rats. Treatment continued for 28 days with blood glucose and weight check weekly. Animals were sacrificed and blood samples collected for biochemical parameters. Results: The blood glucose level of the group treated with ethylacetate was lowered to 142mg/dl which compares favourably with the group treated with glibenclamide (112mg/dl) as opposed to the diabetic untreated group (380mg/dl) at the end of four weeks of treatment. Ethylacetate fraction treated rats showed the least percentage weight loss while there is a significant weight loss (= 0.05) in the diabetic rats Conclusion: Ethylacetate fraction of F.albida showed remarkable effect on blood glucose level and reduced the weight loss in diabetic rats and thus more promising to be further evaluated for bioactive substances.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"12 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84848707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

In vitro anticancer activity of methanol extract of Cladophora spp. against HT-29 cell line 克拉多佛甲醇提取物对HT-29细胞株的体外抗癌活性研究

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1203075561

N. Theresita Shanthi, S. Murugesan, M. Kotteswari

引用次数: 1

Studied on the Bioremediation Effect of Some Selected Microbes on Domestic Sewage Water 部分微生物对生活污水的生物修复效果研究

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-07-01 DOI: 10.9790/3008-1203072123

P. Agrawal

引用次数: 1