Chemistry - A European Journal最新文献_第6页

Intepirdine Derivatives Possessing Dual 5HT6 Antagonism / HDAC6 Inhibitory Activity. 具有双抗5HT6 /抑制HDAC6活性的间皮丁衍生物

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-22 DOI: 10.1002/chem.202500025

Andreas Gkanas, Maria Koutiva, Theodora Katsila, Vivi Bafiti, Minos-Timotheos Matsoukas, Vasilios Panagiotopoulos, Andrzej J Bojarski, Theodoros Gkouvitsas, Georgios Moukas, Gerasimos Rassias

{"title":"Intepirdine Derivatives Possessing Dual 5HT6 Antagonism / HDAC6 Inhibitory Activity.","authors":"Andreas Gkanas, Maria Koutiva, Theodora Katsila, Vivi Bafiti, Minos-Timotheos Matsoukas, Vasilios Panagiotopoulos, Andrzej J Bojarski, Theodoros Gkouvitsas, Georgios Moukas, Gerasimos Rassias","doi":"10.1002/chem.202500025","DOIUrl":"https://doi.org/10.1002/chem.202500025","url":null,"abstract":"Alzheimer's Disease (AD) impacts significantly the quality of life of people aged over 65 years old, while millions more suffer from other types of dementia, yet no effective drugs exist. The few approved drugs in this area address mostly the associated symptoms, while several selective agents acting on promising targets have failed in clinical trials. The complexity of neurodegenerative diseases has prompted multitargeting ligands as the new paradigm, where more than one biological mechanism may be perturbed synergistically. In this context, we explored the design and synthesis of dual 5-ΗΤ6 antagonists / HDAC6 inhibitors since these actions have been individually demonstrated to elicit cognitive-enhancing effects. Prototypes with this dual action on a GPCR and an enzyme were designed and synthesized by tethering an aryl-hydroxamic acid unit, an established pharmacophore for HDAC6 inhibition, to the piperazine of intepirdine, a potent 5-ΗΤ6 antagonist. A new gram-scale synthesis of intepirdine was developed followed by attaching different types of arylhydroxamic acids. Derivative RG-283AG emerged to possess sub-micromolar potency toward HDAC6 inhibition (IC50 0.54 μμ), nanomolar affinity (Ki 0.7 nM) for 5-HT6 receptor and favorable BBB penetration capacity, thus constituting the first example of a dual-acting 5-ΗΤ6 / HDAC6 ligand with potential cognitive-enhancing properties.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e00025"},"PeriodicalIF":3.7,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nucleoside Reactions Shed Light on the Chemical Processes Underlying Interstrand Cross-Link Formation at Apurinic/Apyrimidinic Sites in Duplex DNA. 核苷反应揭示了双链DNA中无尿嘧啶/无嘧啶位点上链间交联形成的化学过程。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-21 DOI: 10.1002/chem.202501666

Garam Shim, Michael Catalano, Anuoluwapo Gomina, Tanhaul Islam, Kent S Gates

{"title":"Nucleoside Reactions Shed Light on the Chemical Processes Underlying Interstrand Cross-Link Formation at Apurinic/Apyrimidinic Sites in Duplex DNA.","authors":"Garam Shim, Michael Catalano, Anuoluwapo Gomina, Tanhaul Islam, Kent S Gates","doi":"10.1002/chem.202501666","DOIUrl":"https://doi.org/10.1002/chem.202501666","url":null,"abstract":"Apurinic/apyrimidinic (AP) sites in DNA can give rise to interstrand cross-links via reactions of the ring-opened AP-aldehyde residue with the exocyclic amino groups of 2'-deoxyadenosine, 2'-deoxyguanosine, and 2'-deoxycytosine residues (dA, dG, and dC) on the opposing strand to give imine/N-glycosylamine linkages. Endogenous AP-derived cross-links in cellular DNA could contribute to cancer, aging, and neurodegeneration. The yields of AP-derived cross-links produced by the various nucleobases vary widely, and, until now, it remained unclear whether these differences might simply reflect differences in the inherent reactivities of the nucleobases. To shed light on this question, we examined reactions of a nucleosidic AP model compound, 3,5-bis-O-methyl-2-deoxy-D-ribofuranose (1), with the canonical nucleosides (dA, dG, and dC) and the noncanonical nucleoside, 2-aminopurine-2'-deoxyriboside (2AP). The trends observed for the equilibrium yields of the nucleoside cross-links did not mirror yields of the respective cross-links observed in the context of duplex DNA. The results provide evidence that the inherent reactivity of the nucleobases alone does not determine yields of AP-derived cross-links in duplex DNA. Rather, the differences in yields for the various AP-derived cross-links must reflect effects exerted by the 3D structure of double helical DNA on the cross-linking processes.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e01666"},"PeriodicalIF":3.7,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ru(II)-Based Photo-Antibiotics: Light-Driven Eradication of Bacterial Biofilm and Rapid Healing of Infective Wounds in Wistar Rat. Ru（II）基光抗生素：光驱动细菌生物膜的清除和Wistar大鼠感染伤口的快速愈合。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-21 DOI: 10.1002/chem.202502095

Arif Ali Mandal, Anjali Upadhyay, Apurba Mandal, Subhransu Sekhar Sahoo, Ashish Kumar Agrawal, Sudip Mukherjee, Samya Banerjee

{"title":"Ru(II)-Based Photo-Antibiotics: Light-Driven Eradication of Bacterial Biofilm and Rapid Healing of Infective Wounds in Wistar Rat.","authors":"Arif Ali Mandal, Anjali Upadhyay, Apurba Mandal, Subhransu Sekhar Sahoo, Ashish Kumar Agrawal, Sudip Mukherjee, Samya Banerjee","doi":"10.1002/chem.202502095","DOIUrl":"https://doi.org/10.1002/chem.202502095","url":null,"abstract":"Three novel Ru(II)-based photoantibiotics, viz., [Ru(phtpy)(N,N,N)2](PF6)2, where N,N,N = 4'-phenyl-2,2':6',2″-terpyridine (phtpy, Ru1), 4-([2,2':6',2''-terpyridin]-4'-yl)-N,N-dimethylaniline (NMe2tpy, Ru2), trifluoromethylphenyl)-2,2':6',2''-terpyridine (CF3tpy, Ru3) were developed with excellent photostability for visible light-activated antibacterial activities and infective wound healing. Ru1-Ru3 exhibited an absorption in the 400-600 nm range, beneficial for antibacterial photodynamic therapy (aPDT) application. Upon visible light exposure (400-700 nm), Ru1-Ru3 inhibited bacterial growth of Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Bacillus subtilis (B. subtilis), due to the effects of oxidative stress via ROS generation and photo-oxidation of NADH. Ru3 was identified as a lead antibiotic that further showed antibiofilm activities against E. coli under visible light exposure. Ru3 was found to be biocompatible against rat red blood cells and human embryonic kidney cells. Ru3 + light promoted rapid healing of infected wounds within 9 days in an E. coli-induced rat model, highlighting its potential future use in healthcare.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e02095"},"PeriodicalIF":3.7,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photocatalytic CO₂ Reduction to Multi-Carbon Products. 光催化CO2还原多碳产物。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-21 DOI: 10.1002/chem.202502207

Ning-Yu Huang, Di Chen, Yu-Tao Zheng, Qiang Xu

{"title":"Photocatalytic CO2 Reduction to Multi-Carbon Products.","authors":"Ning-Yu Huang, Di Chen, Yu-Tao Zheng, Qiang Xu","doi":"10.1002/chem.202502207","DOIUrl":"https://doi.org/10.1002/chem.202502207","url":null,"abstract":"Photocatalytic CO2 reduction represents a sustainable pathway for mitigating carbon emissions and producing renewable chemicals by utilizing solar energy. While extensive research has been dedicated to single-carbon (C1) products, the selective formation of multi-carbon (C2+) compounds, such as ethylene, ethane, ethanol and acetic acid, has garnered increasing attention due to their higher energy density and broader industrial relevance. However, achieving efficient C─C coupling under mild photocatalytic conditions remains a formidable challenge, hindered by complex reaction pathways, sluggish kinetics and competitive side reactions. In this review, recent advances in photocatalytic CO2 reduction to C2+ products was systematically summarized, focusing on fundamental reaction mechanisms, rational photocatalyst design strategies, including atomically dispersed active sites, cocatalyst loading, defect engineering, and localized surface plasmon resonance (LSPR). By bridging mechanistic understanding with materials innovation, this review provides a comprehensive framework for guiding the development of next-generation photocatalytic systems for efficient and selective CO2-to-C2+ conversion, contributing to sustainable carbon utilization and circular chemical economy.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e02207"},"PeriodicalIF":3.7,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Xanthine Base Pairing with 2-Aminoadenine and Canonical Bases in Purine Tracts of Watson-Crick DNA: Impact of Purine-, 7-Deazapurine- and 8-Aza-7-deazapurine Heterocyclic Skeletons on Duplex Stability. 沃森-克里克DNA嘌呤束中黄嘌呤碱基与2-氨基腺苷和典型碱基的配对：嘌呤-、7-去氮杂嘌呤-和8-氮杂嘌呤-7-去氮杂嘌呤杂环骨架对双相稳定性的影响。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-20 DOI: 10.1002/chem.202501227

Dasharath Kondhare, Matthias Letzel, Peter Leonard

{"title":"Xanthine Base Pairing with 2-Aminoadenine and Canonical Bases in Purine Tracts of Watson-Crick DNA: Impact of Purine-, 7-Deazapurine- and 8-Aza-7-deazapurine Heterocyclic Skeletons on Duplex Stability.","authors":"Dasharath Kondhare, Matthias Letzel, Peter Leonard","doi":"10.1002/chem.202501227","DOIUrl":"https://doi.org/10.1002/chem.202501227","url":null,"abstract":"The impact of purine, 7-deazapurine and 8-aza-7-deazapurine heterocyclic skeletons on the stability of the xanthine-2-aminoadenine base pair is reported. Beyond that, base-pairing of xanthine nucleosides opposite canonical nucleobases is studied. To this end, a building block of 8-aza-7-deaza-2'-deoxyxanthosine was prepared using 8-aza-7-deaza-2'-deoxyguanosine as starting material. A simplified synthesis for large-scale production is presented for the phosphoramidite of 2-amino-7-bromo-7-deaza-2'-deoxyadenosine (2-NH2Br7c7z8Ad). Hybridization of oligonucleotides gave duplexes containing single or multiple incorporations of xanthine-2-aminoadenine base pairs with different combinations of nucleobases. From melting curves and Tm values, it became apparent that the most stable duplexes contained base pairs of 2-NH2Br7c7z8Ad with xanthine nucleosides. Under these, the 7-deazaxanthine-2-NH2Br7c7z8Ad base pair reached the stability of dT-2-NH2Br7c7z8Ad and dG-dC pairs. 7-Deazaxanthine located opposite 2-aminoadenine residues resulted in higher duplex stability compared to xanthine or 8-aza-7-deazaxanthine. For 2-aminoadenine residues, the base pair stability followed the order 2-amino-8-aza-7-bromo-7-deazaadenine > 2-aminoadenine > 7-deazaadenine. The impact of pK values became obvious from the increased stability of xanthine-2-aminoadenine pairs by decreasing the pH. Single incorporations of xanthine residues opposite canonical nucleobases displayed inhomogeneous pairing properties. Tracts of three xanthine residues in front of adenine and guanine furnished stable duplexes, whereas with cytosine and thymine, duplex formation was hindered.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e01227"},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NIR-II Photothermal Conversion in Spin Crossover Metal-organic Frameworks. 自旋交叉金属有机骨架中的NIR-II光热转换。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-20 DOI: 10.1002/chem.202502076

Guang Yang, Lu Yu, Si-Guo Wu, Le Ye, Jia-Chuan Liu, Jing-Yu Wang, Kai-Ping Xie, Zhao-Ping Ni, Ming-Liang Tong

{"title":"NIR-II Photothermal Conversion in Spin Crossover Metal-organic Frameworks.","authors":"Guang Yang, Lu Yu, Si-Guo Wu, Le Ye, Jia-Chuan Liu, Jing-Yu Wang, Kai-Ping Xie, Zhao-Ping Ni, Ming-Liang Tong","doi":"10.1002/chem.202502076","DOIUrl":"https://doi.org/10.1002/chem.202502076","url":null,"abstract":"The synthesis of multifunctional materials that exhibit two or more distinct physicochemical properties is critical for the development of advanced smart materials. To date, the research regarding the near-infrared II (NIR-II) photothermal properties of spin crossover (SCO) materials remains scarce. Here, we synthesized an inverse-Hofmann-type cationic framework, [Fe{Ag(CN)2}(TTF(py)4)]+ (1, TTF(py)4 = tetra(4-pyridyl)tetrathiafulvalene), which exhibits hysteretic SCO behavior. By introducing p-aminoazobenzene (Azo-NH2) and pyrene (Pyr) into 1, two solvent-free derivatives, 1@Azo-NH2 and 1@Pyr, incorporating free radicals were generated. NIR-II photothermal experiments revealed the outstanding photothermal properties of 1@Azo-NH2 and 1@Pyr under 1064 nm laser irradiation. Solar-driven water evaporation experiment demonstrated that 1@Pyr achieved a water evaporation rate of 0.9197 kg m-2 h-1 with an efficiency of 63.9%. This represents the first demonstration of outstanding NIR-II photothermal conversion performance in an inverse-Hofmann-type metal-organic framework incorporating free radicals generated through host-guest interactions. Our findings underscore the critical importance of incorporating NIR absorption units into SCO systems, providing new insights for the development of intelligent multifunctional materials.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e02076"},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphene Quantum Dots Drive Spontaneous Metal Reduction to Form Stable and Electroactive Core-Shell Nanocolloids. 石墨烯量子点驱动自发金属还原形成稳定和电活性核壳纳米胶体。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-20 DOI: 10.1002/chem.202501997

Josefina Ventre, Santiago D Barrionuevo, Jorge M Nuñez, Agustina Renna, Ricardo Faccio, Myriam H Aguirre, Martin G Bellino, Francisco J Ibañez

{"title":"Graphene Quantum Dots Drive Spontaneous Metal Reduction to Form Stable and Electroactive Core-Shell Nanocolloids.","authors":"Josefina Ventre, Santiago D Barrionuevo, Jorge M Nuñez, Agustina Renna, Ricardo Faccio, Myriam H Aguirre, Martin G Bellino, Francisco J Ibañez","doi":"10.1002/chem.202501997","DOIUrl":"https://doi.org/10.1002/chem.202501997","url":null,"abstract":"This work demonstrates a spontaneous synthesis of ∼8.0, ∼7.0, and ∼3.0 nm diameter Au, Ag, and Pt cores; respectively, wrapped by as-synthesized crystalline graphene-quantum dots (GQDs). Functional sp2- and sp3-hybridized carbons play a crucial role upon the synthesis, electronic distribution at the interface, and conductive sites for improving the electrocatalytic response. Au nanohybrids (NHs) demonstrated two-fold increase in current density with respect to conventional citrate-coated Au nanoparticles. This was attributed to conductive sp2- hybridized carbons and the gain of charge density at the surface of Au as demonstrated by DFT calculations. Due to the sp3-carbons at the shell, these NHs also behave like simple chemical compounds because they can be precipitated, stored for long periods of time, and redispersed without apparent changes in their properties. The resultant nanocolloids exhibit exceptional stability under harsh conditions. These attributes make them useful NHs with great potential for broad applications.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e01997"},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorine-Free Biomass-Derived Ionic Liquid Electrolytes: Ion Dynamics and Electrochemical Properties. 无氟生物质衍生离子液体电解质：离子动力学和电化学性质。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-20 DOI: 10.1002/chem.202501641

Sayantika Bhakta, Gaurav Tatrari, Maiia Rudakova, Andrei Filippov, Faiz Ullah Shah

{"title":"Fluorine-Free Biomass-Derived Ionic Liquid Electrolytes: Ion Dynamics and Electrochemical Properties.","authors":"Sayantika Bhakta, Gaurav Tatrari, Maiia Rudakova, Andrei Filippov, Faiz Ullah Shah","doi":"10.1002/chem.202501641","DOIUrl":"https://doi.org/10.1002/chem.202501641","url":null,"abstract":"Here we present the synthesis, physical characterization, and transport as well as electrochemical properties of a novel class of ten ionic liquids (ILs) derived from biomass. Two biomass derived anions such as furan-2-carboxylate [FuA] and tetrahydrofuran-2-carboxylate [HFuA] are coupled to a range of nitrogen heterocyclic cations to create the ILs, for which the nature of cation controlled their properties. For instance, the thermal decomposition temperature ranges from 183 to 259 °C, the glass transition temperature from - 47 to - 70 °C, and the ionic conductivity from 0.002 to 1.4 mS cm-1 at 20 °C. The supercapacitors prepared using [EPy][FuA] and [EMPip][FuA] exhibited specific capacitances of 99 F g-1 and 70 F g-1 at 0.2 A g-1, respectively. The [EPy][FuA]-based supercapacitor achieved an energy density of 56 Wh kg-1 as well as a power density of 410 W kg-1 at 0.2 A g-1, while the [EMPip][FuA]-based supercapacitor achieved an energy density of 36 Wh kg-1 and a power density of 360 W kg-1 at 0.2 A g-1. In addition, the supercapacitors retained 98% and 94% of their initial capacitances after 6000 cycles, for [EPy][FuA] and [EMPip][FuA] electrolytes, respectively.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e01641"},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials. 凝聚囊泡作为合成生物学和智能材料的自适应平台。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-19 DOI: 10.1002/chem.202502268

Francesco Vicentini, Federica Battistin, Pierangelo Gobbo

引用次数: 0

Synthesis of Anthraquinone Mono- and Diboron Complexes with Near-Infrared Panchromatic Absorption. 蒽醌类单、二硼配合物的近红外全色吸收合成。

IF 3.7 2区化学

Chemistry - A European Journal Pub Date : 2025-08-19 DOI: 10.1002/chem.202501915

Yasuhiro Kubota, Ayumi Ogasawara, Shota Mizuno, Toshiyasu Inuzuka, Kazumasa Funabiki

{"title":"Synthesis of Anthraquinone Mono- and Diboron Complexes with Near-Infrared Panchromatic Absorption.","authors":"Yasuhiro Kubota, Ayumi Ogasawara, Shota Mizuno, Toshiyasu Inuzuka, Kazumasa Funabiki","doi":"10.1002/chem.202501915","DOIUrl":"10.1002/chem.202501915","url":null,"abstract":"Anthraquinone monoboron complexes 3 and 4, possessing a donor-acceptor (D-A) structure, and diboron complexes 7 and 8, featuring a donor-acceptor-donor (D-A-D) structure, were readily synthesized in two steps from commercially available reagents. These boron complexes adopt a β-iminoenolate structure and their absorption properties are markedly affected by the type of the substituent groups. The unsubstituted monoboron complex 3 (fwhm = 3,950 cm-1) and diboron complex 7 (fwhm = 2,510 cm-1) exhibited sharp UV-Vis-NIR absorption spectra, which can be attributed to increased molecular rigidity induced by boron coordination. In contrast, the dimethylamino-substituted monoboron complex 4 (fwhm = 7,580 cm-1) and diboron complex 8 (fwhm = 8,770 cm-1) showed broad absorption bands due to the enhanced intramolecular charge-transfer (ICT) character. Dimethylamino-substituted monoboron complex 4 and diboron complex 8 exhibited panchromatic absorption ranging from 400 nm to 1,000 nm and 400 nm to 1,250 nm, respectively. The panchromatic absorption of the dimethylamino-substituted boron complexes 4 and 8 is attributed not only to the enhanced ICT character but also to the combination of multiple transitions.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e01915"},"PeriodicalIF":3.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0