W. Badgett, S. Hahn, D. Torretta, J. Meier, J. Gunderson, Denise Osterholm, David Saranen
{"title":"Upgrade of the Minos+ experiment data acquisition for the high energy NuMI beam run","authors":"W. Badgett, S. Hahn, D. Torretta, J. Meier, J. Gunderson, Denise Osterholm, David Saranen","doi":"10.1109/NSSMIC.2014.7431144","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431144","url":null,"abstract":"The Minos+ experiment is an extension of the Minos experiment at a higher energy and more intense neutrino beam, with the data collection having begun in the fall of 2013. The neutrino beam is provided by the Neutrinos from the Main Injector (NuMI) beam-line at Fermi National Accelerator Laboratory (Fermilab). The detector apparatus consists of two main detectors, one underground at Fermilab and the other in Soudan, Minnesota with the purpose of studying neutrino oscillations at a base line of 735 km. The original data acquisition system has been running for several years collecting data from NuMI, but with the extended run from 2013, parts of the system needed to be replaced due to obsolescence, reliability problems, and data throughput limitations. Specifically, we have replaced the front-end readout controllers, event builder, and data acquisition computing and trigger processing farms with modern, modular and reliable devices with few single points of failure. The new system is based on gigabit Ethernet TCP/IP communication to implement the event building and concatenation of data from many front-end VME readout crates. The simplicity and partitionability of the new system greatly eases the debugging and diagnosing process. The new system improves throughput by about a factor of three compared to the old system, up to 800 megabits per second, and has proven robust and reliable in the current run.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115488779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Caicedo, B. Bergmann, M. Králík, V. Kraus, C. Leroy, S. Pospíšil, M. Suk, Z. Vykydal
{"title":"Characterization of a Timepix detector-based hodoscope for the measurement of mixed radiation fields","authors":"I. Caicedo, B. Bergmann, M. Králík, V. Kraus, C. Leroy, S. Pospíšil, M. Suk, Z. Vykydal","doi":"10.1109/NSSMIC.2014.7431064","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431064","url":null,"abstract":"A hodoscope based on pixel semiconductor detectors of the Timepix type (ATLAS-TPX) equipped with neutron converters and operating with common read-out was designed for remote measurements in mixed radiation field environments.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115671480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio J. González, F. Sánchez, P. Conde, S. Aussenhofer, D. Gareis, R. Pani, R. Pellegrini, M. Bettiol, A. Fabbri, S. Majewski, Christopher Bauer, A. Stolin, P. Martone, J. Bert, D. Visvikis, C. Jackson, John Murphy, K. O'Neill, J. Benlloch
{"title":"A novel brain PET insert for the MINDView project","authors":"Antonio J. González, F. Sánchez, P. Conde, S. Aussenhofer, D. Gareis, R. Pani, R. Pellegrini, M. Bettiol, A. Fabbri, S. Majewski, Christopher Bauer, A. Stolin, P. Martone, J. Bert, D. Visvikis, C. Jackson, John Murphy, K. O'Neill, J. Benlloch","doi":"10.1109/NSSMIC.2014.7430885","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7430885","url":null,"abstract":"The Multimodal Imaging of Neurological Disorders (MINDview) project aims to develop a high resolution and sensitivity dedicated brain Positron Emission Tomography (PET) system capable of visualizing neurotransmitter pathways and their disruptions for mental disorders for diagnosis and treatment follow-up. Moreover, this compact PET system should be fully compatible with a Magnetic Resonance Imaging (MRI) system in order to allow its operation as a brain insert in a hybrid imaging setup with most MRI scanners. The proposed design will enable current installed MRI base to be easily upgraded to PET/MRI systems. The current design for the PET insert consists of a 3 rings configuration, 20 modules per ring, with an axial field of view of ~15 cm and a geometrical aperture of ~33 cm in diameter. When coupled to the new head Radio Frequency (RF) coil, the inner diameter of the complete PET-RF coil insert is reduced to 26 cm. Main features of the PET detector insert for the MINDView project in terms of its overall design, electronic readout, and MRI compatibility will be presented. In addition, the main parameters of the PET detector insert, such as expected spatial and energy resolution, depth of interaction (DOI) capabilities and sensitivity will be discussed in terms of the different approaches considered so far for the construction of the first MINDView prototype. Laboratory tests results associated with the current MINDView PET module concept in terms of key parameters optimisation such as scintillator crystal, photosensor configuration and signal readout will be also presented.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124240442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nanopattern multi-well avalanche selenium detector with picosecond time resolution","authors":"A. Goldan, J. Rowlands, Ming Lu, Wei Zhao","doi":"10.1109/NSSMIC.2014.7431215","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431215","url":null,"abstract":"For the first time, we propose using amorphous selenium (a-Se) as the photoconductive material for time-of-flight (TOF) detectors. The major drawback of a-Se is its poor time-resolution and low mobility due to shallow-traps, problems that must be circumvented for TOF applications. Thus, we propose a nanopattern multi-well a-Se detector to enable the utilization of both avalanche multiplication gain and unipolar time-differential (UTD) charge sensing in one device. Advantages of avalanche-mode a-Se are having photoconductive gain and band transport in extended states with the highest possible mobility and negligible trapping. Most importantly, UTD charge sensing enables operating the detector at its theoretical limit of charge diffusion. Our simulation results show that UTD charge sensing in avalanche-mode a-Se improves time-resolution by more than 3 orders-of-magnitude and proves very promising to achieve for the first time the ultimate goal of 10 ps time-resolution with a material that is low-cost and uniformly scalable to large-area.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124549538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mohammadi, Y. Hirano, F. Nishikido, E. Yoshida, A. Kitagawa, T. Inaniwa, T. Yamaya
{"title":"Feasibility of secondary 15O beam production for in-beam PET","authors":"A. Mohammadi, Y. Hirano, F. Nishikido, E. Yoshida, A. Kitagawa, T. Inaniwa, T. Yamaya","doi":"10.1109/NSSMIC.2014.7431003","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431003","url":null,"abstract":"For the purpose of in situ visualization of an irradiation field in particle therapy, it is ideal to use radioactive beams for in-beam positron emission tomography (PET) imaging. In the Heavy Ion Medical Accelerator in Chiba (HIMAC), there is a beam course to produce 11C and 10C as secondary beams, but generation of 15O has never been investigated. This study was devoted to analysis of the feasibility of secondary 15O production for in-beam PET by 16O primary beam in different absorbing materials (targets) with various thicknesses in order to find out the optimum target material and its thickness. The study was performed using analytical method, LISE++ code, and the Monte Carlo method, PHITS code. The calculation results showed that the highest intensity of the secondary 15O beam observed for primary 16O beam decelerating in liquid hydrogen but practically almost impossible to apply. The final optimum target was considered to be polyethylene with thickness of 11 cm. The 15O beam was produced in the HIMAC secondary beam line using the optimum target and the in-beam PET imaging was presented for a PMMA phantom irradiated with the produced beam.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124563542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Angelis, J. Gillam, W. Ryder, A. Kyme, R. Fulton, S. Meikle
{"title":"Efficient time-weighted sensitivity image calculation for motion compensated list mode reconstruction","authors":"G. Angelis, J. Gillam, W. Ryder, A. Kyme, R. Fulton, S. Meikle","doi":"10.1109/NSSMIC.2014.7430947","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7430947","url":null,"abstract":"Accurate motion compensated image reconstruction of freely moving small animals requires the exact calculation of the time-weighted sensitivity correction factors. Back-projection of all possible lines of response for every recorded pose is a computationally intensive task, which requires impractically long reconstruction times. In this work we investigated an approach to accelerate this task, by randomly sampling the lines of response and the poses that are used to calculate the time-averaged sensitivity image. Two phantom datasets, acquired on the microPET Focus220 scanner, were used to quantify errors introduced in the randomly sampled sensitivity images and propagated to the final reconstructed images. In addition, the qualitative performance of the proposed methodology was assessed by reconstructing a freely moving rat acquisition. Results showed that randomisation can severely amplify the noise in the reconstructed images, especially when few LORs are sampled. However, such errors can be suppressed by post-filtering the randomised sensitivity images prior to reconstruction (e.g. 2 mm FHWM). Such an approach can substantially reduce the computational time involved during the estimation of the time-averaged sensitivity image for motion compensated image reconstruction.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114354151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on the conformal conversion in the Open Electrical Impedance Tomography","authors":"P. Yan, J. Yao, R. A. Payne, H. Jia, L. Jin","doi":"10.1109/NSSMIC.2014.7430817","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7430817","url":null,"abstract":"This paper presents a feasible method and validated algorithm for the Open Electrical Impedance Tomography (OEIT) problem which will reduce the computational complexity and the errors in employing the Maxwell equations and implementing the boundary conditions under test. Considering the tested area of skin could be assumed as a plate condenser. So the model like this often exists some fringe effects in practice which may lead to the Maxwell equations are no longer applicable even the divergence of data. The goal of this paper is to solve the problem by developing a way to making an open rectangle region mapped to a closed circular region based on the conformal conversion. For this purpose, a set of conformal mapping formulas has been finally worked out. In addition, the format of boundary conditions of the skin model proved to be the same in a 3D domain. Eventually a conclusion of this work can be drawn from the substantial simulations for its effectiveness under certain conditions.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114595516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The LHCb Vertex Locator upgrade","authors":"P. Tsopelas","doi":"10.1109/NSSMIC.2014.7431238","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431238","url":null,"abstract":"The upgrade of the LHCb experiment, planned for 2018, will transform the experiment to a trigger-less system reading out the full detector at 40 MHz event rate with all data reduction algorithms executed in high level software on a computing farm. The Vertex Locator (VELO) detector which surrounds the interaction region is used to reconstruct primary and secondary vertices and measure the flight distance of long-lived particles. The upgraded VELO will be a hybrid pixel detector read out by the VeloPix ASIC with on-chip zero-suppression. The hottest region will have peak pixel hit rates of 900 Mhits/s yielding a total data rate more than 3 Tbit/s for the upgraded VELO. The data will be read out on high-speed electrical and optical serial links. The detector modules are located in a secondary vacuum, separated from the beam vacuum by a thin custom made foil. The detector halves are retracted during injection of the LHCb beams and closed when the beams are declared stable. In the closed position the innermost sensitive pixels are at 5.1 mm from the beams. The material budget will be minimised by the use of evaporative CO2 coolant circulating in micro channels within 400 μm thick silicon substrates. Microchannel cooling brings many advantages: very efficient heat transfer with almost no temperature gradients across the module, no CTE mismatch with silicon components, and low material contribution. The current status of the VELO upgrade will be described together with a presentation of recent test results.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114543096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Markovic, A. Dragone, P. Caragiulo, R. Herbst, K. Nishimura, B. Reese, S. Herrmann, P. Hart, G. Blaj, J. Segal, A. Tomada, J. Hasi, G. Carini, C. Kenney, G. Haller
{"title":"Design and characterization of the ePix100a: A low noise integrating pixel ASIC for LCLS detectors","authors":"B. Markovic, A. Dragone, P. Caragiulo, R. Herbst, K. Nishimura, B. Reese, S. Herrmann, P. Hart, G. Blaj, J. Segal, A. Tomada, J. Hasi, G. Carini, C. Kenney, G. Haller","doi":"10.1109/NSSMIC.2014.7431230","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7431230","url":null,"abstract":"ePix100 is the first variant of a novel class of integrating pixel ASICs architectures optimized for the processing of signals in second generation LINAC Coherent Light Source (LCLS) X-Ray cameras. ePix ASICs are based on a common platform composed of a random access analog matrix of pixel with global shutter, fast parallel column readout, and dedicated sigma-delta analog to digital converters per column. The ePix100 variant is optimized for low noise application requiring high spatial resolution and fast frame rates. The ASIC has pixels of 50×50 μm2 size arranged in a 352×384 array, a resolution of 50e- r.m.s., and a signal range of 35fC (100 photons at 8keV). In its final version it will be able to sustain a frame rate of 1 kHz. Currently a full-size analog version, ePix100a, has been fabricated in TSMC CMOS 0.25 μm technology. The ePix100a has been fully characterized and results are here reported.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117313650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Population-based functional template priors for regularized PET reconstruction","authors":"Philip Novosad, A. Reader","doi":"10.1109/NSSMIC.2014.7430938","DOIUrl":"https://doi.org/10.1109/NSSMIC.2014.7430938","url":null,"abstract":"We outline a possible method for exploiting population-based data for regularization in iterative PET reconstruction. Multi-modal and high-resolution mean shape templates are derived from a set of co-registered PET-MR images. The functional component of the template, representing the average radiotracer distribution among the images in the set, is used in a Bayesian reconstruction scheme for regularization of a given image. Unlike conventional anatomical-based priors, our proposed method makes no assumptions about relations between anatomy and function. Instead of regularizing based on differences between anatomy and function, we regularize based on differences between a mean functional image and a given functional image. Our proposed method outperforms both conventional MLEM and quadratic priors.","PeriodicalId":144711,"journal":{"name":"2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122082609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}