International Urology and Nephrology最新文献

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Comparison of the mid-term outcomes of laparoscopic and percutaneous nephroscopic laser unroofing for the treatment of single renal cyst: a single-center retrospective study. 比较腹腔镜和经皮肾镜激光去顶术治疗单发肾囊肿的中期疗效:一项单中心回顾性研究。
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-04 DOI: 10.1007/s11255-025-04382-9
Zhen Tang, Baode Lu, Yan Zhang, Jiao Peng, Fenfen Zhao, Zengnan Mo
{"title":"Comparison of the mid-term outcomes of laparoscopic and percutaneous nephroscopic laser unroofing for the treatment of single renal cyst: a single-center retrospective study.","authors":"Zhen Tang, Baode Lu, Yan Zhang, Jiao Peng, Fenfen Zhao, Zengnan Mo","doi":"10.1007/s11255-025-04382-9","DOIUrl":"https://doi.org/10.1007/s11255-025-04382-9","url":null,"abstract":"<p><strong>Purpose: </strong>Renal cysts are the most common benign disease of the kidneys, and their increasing size cause compression symptoms that require surgical intervention. In this study, we compared the safety, efficacy and prognosis of percutaneous nephroscopic laser unroofing (PNLU) with those of laparoscopic unroofing (LU) for simple renal cysts.</p><p><strong>Methods: </strong>Data from patients with single renal cysts who underwent PNLU or LU between Jan 2018 and Dec 2023 were collected and followed up thereafter. Baseline characteristics, perioperative events, blood test results and postoperative complications were compared. Recurrence-free survival (RFS) was also compared via survival analysis. Subgroup analyses were conducted in the PNLU group, including the 980 nm laser and Holmium laser groups.</p><p><strong>Results: </strong>A total of 75 patients were included, 35 of whom underwent PNLU and 40 of whom underwent LU. Compared with LU, PNLU requires only one surgical incision and is a shorter procedure, causes less blood loss, requires fewer urinary catheter days, is known for quicker drainage tube removal, requires a shorter postoperative hospital stay, has lower hospitalization costs, induces a weaker postoperative inflammatory response, and is associated with a lower incidence of abdominal distension. There was no significant difference in RFS between the PNLU and LU groups. In the subgroup analyses of PNLU, no significant differences were observed between the 980 nm laser and Holmium laser groups.</p><p><strong>Conclusion: </strong>PNLU is safe, effective and cost-effective for single renal cysts and known for a low complication rate, and its mid-term prognosis is similar to that of laparoscopic surgery.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secular trends in cytomegalovirus (CMV) risk and outcomes: results from a 10-year longitudinal cohort study in adult kidney transplant recipients. 巨细胞病毒 (CMV) 风险和预后的周期性趋势:成人肾移植受者 10 年纵向队列研究的结果。
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-04 DOI: 10.1007/s11255-025-04399-0
Amy Perry, Karim Soliman, Erika Andrade, Zaid Mesmar, Morgan Overstreet, Tibor Fulop, Isabel K Calimlim, Courtney Harris, David J Taber
{"title":"Secular trends in cytomegalovirus (CMV) risk and outcomes: results from a 10-year longitudinal cohort study in adult kidney transplant recipients.","authors":"Amy Perry, Karim Soliman, Erika Andrade, Zaid Mesmar, Morgan Overstreet, Tibor Fulop, Isabel K Calimlim, Courtney Harris, David J Taber","doi":"10.1007/s11255-025-04399-0","DOIUrl":"https://doi.org/10.1007/s11255-025-04399-0","url":null,"abstract":"<p><strong>Background: </strong>The goal of this study was to determine the secular trends in the incidence of CMV sero-mismatch (D+/R -) and if these trends meaningfully impact clinical outcomes.</p><p><strong>Methods: </strong>This was a single-center longitudinal cohort study in adult kidney recipients transplanted between Jan 2012 and June 2021 with follow-up through June 2022. Baseline and follow-up data were collected. Univariate and multivariate statistics were used to analyze the data.</p><p><strong>Results: </strong>2,392 kidney transplants were performed during the study period; 132 patients did not meet inclusion criteria. The mean age was 52 years, 41% were female, 57% were black, and 19% were CMV D + /R -. The odds of being CMV high-risk increased by 6% each year (OR 1.06, 1.02-1.10 p = 0.003); 48% of the variability associated with CMV serostatus was explained by transplant year (R<sup>2</sup> = 0.478, p = 0.002). Sequential modeling demonstrated that CMV D + /R - serostatus was a substantial risk factor for CMV infection (HR 5.7, 4.5-7.3), CMV disease (HR 8.4, 3.9-18.0), CMV resistance (HR 17.9, 3.8-84.2), CMV refractory infection (HR 35, 4-280), late CMV infection (HR 12.0, 8.3-17.1), acute rejection, and hospitalization for opportunistic infections. Secular trend analysis demonstrated that CMV infections, CMV resistance, and late CMV increased in incidence since 2012. The risks of CMV resistance and late infection was significantly influenced by D + /R - serostatus and transplant year, indicating that this risk is worsening over time.</p><p><strong>Conclusion: </strong>The CMV D + /R - serostatus remains the single most important risk factor for CMV infection, disease, resistance, refractory infection, and late CMV, which appears to be increasing in magnitude.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous laser ablation vs. radical nephroureterectomy: a comparative study on renal pelvic tumors.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-04 DOI: 10.1007/s11255-025-04395-4
Gao Li, Yuanhao Chen, Xin Zhang
{"title":"Percutaneous laser ablation vs. radical nephroureterectomy: a comparative study on renal pelvic tumors.","authors":"Gao Li, Yuanhao Chen, Xin Zhang","doi":"10.1007/s11255-025-04395-4","DOIUrl":"https://doi.org/10.1007/s11255-025-04395-4","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the safety and efficacy of percutaneous laser ablation and radical nephroureterectomy for renal pelvic tumors.</p><p><strong>Methods: </strong>This prospective cohort study included 30 patients diagnosed with renal pelvic tumors who met the established selection criteria. The cohort was divided into two groups: Group I, consisting of 15 patients who underwent percutaneous laser ablation, and Group II, comprising 15 patients who received radical nephroureterectomy. Comprehensive data collection encompassed demographic information, intraoperative and postoperative outcomes, and disease-free survival.</p><p><strong>Results: </strong>The analysis revealed that percutaneous laser ablation offered modest benefits over radical nephroureterectomy in terms of reduced surgical duration (P < 0.01) and shorter hospital stays (P = 0.03). However, in evaluating long-term oncologic outcomes, percutaneous laser ablation did not achieve parity with radical nephroureterectomy. Although the differences in long-term outcomes were not statistically significant (HR: 0.48; 95% CI 0.05-4.92, P = 0.54), radical nephroureterectomy exhibited a slight advantage in disease-free survival.</p><p><strong>Conclusion: </strong>Percutaneous laser ablation presents a safe and effective, less invasive treatment alternative, rendering it a feasible option for patients who are either unable or unwilling to undergo radical nephroureterectomy due to comorbid conditions or personal preferences.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Intravesical administration of highly concentrated hyaluronic acid and chondroitin sulfate as add‑on therapy for chemical cystitis induced by Bacillus Calmette-Guérin (BCG) immunotherapy.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-03 DOI: 10.1007/s11255-025-04404-6
M Gubbiotti, E Rubilotta, M Bacchiani, A Cocci, S Rosadi, S Serni, A Minervini, V Li Marzi
{"title":"Correction: Intravesical administration of highly concentrated hyaluronic acid and chondroitin sulfate as add‑on therapy for chemical cystitis induced by Bacillus Calmette-Guérin (BCG) immunotherapy.","authors":"M Gubbiotti, E Rubilotta, M Bacchiani, A Cocci, S Rosadi, S Serni, A Minervini, V Li Marzi","doi":"10.1007/s11255-025-04404-6","DOIUrl":"https://doi.org/10.1007/s11255-025-04404-6","url":null,"abstract":"","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of selenium supplementation on hemodialysis patients: a meta-analysis.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-03 DOI: 10.1007/s11255-025-04400-w
Qiu Cheng, Dandan Fan, Pengyu Chen, Huaihong Yuan
{"title":"Effect of selenium supplementation on hemodialysis patients: a meta-analysis.","authors":"Qiu Cheng, Dandan Fan, Pengyu Chen, Huaihong Yuan","doi":"10.1007/s11255-025-04400-w","DOIUrl":"https://doi.org/10.1007/s11255-025-04400-w","url":null,"abstract":"<p><strong>Purpose: </strong>Hemodialysis (HD) patients commonly experience enhanced oxidative stress and inflammation, potentially increasing the risk of malnutrition. Selenium levels are typically lower in HD individuals. Selenium deficiency has been identified as a risk factor for oxidative stress and inflammatory responses. Therefore, we intended to perform a meta-analysis to assess the impact of selenium supplementation on HD patients.</p><p><strong>Methods: </strong>PubMed, Embase, Cochrane Library, and Web of Science were searched for randomized controlled trials (RCTs) on the effect of selenium supplementation on HD patients until September 31, 2024. The data analysis was conducted using Stata15.0 software.</p><p><strong>Results: </strong>Seven RCTs, with 2080 participants, were finally included, with 1029 in the selenium group and 1051 in the control group. The meta-analysis unraveled no statistically significant impact of selenium supplementation on body mass index (SMD = 0.15, 95% CI (- 0.20, 0.49), triglyceride [(SMD = - 0.02, 95% CI (- 0.44, 0.41)], total cholesterol [(SMD = - 0.18, 95%CI (- 0.41, 0.05)], low-density lipoprotein [(SMD = - 0.37, 95% CI (- 1.04, 0.31)], high-density lipoprotein cholesterol [(SMD = 0.15, 95% CI (- 0.54, 0.84)], C-reactive protein [(SMD = - 0.10, 95% CI (- 0.46, 0.27)], ferritin [(SMD = - 0.02, 95% CI (- 0.29, 0.26)], Hx-C reactive protein [(SMD = 0.00, 95% CI (- 1.02, 1.03)], and hemoglobin [(SMD = 0.01, 95% CI (- 0.57,0.59)]. Only selenium levels were significantly increased after selenium supplementation [SMD = 2.83, 95% CI (2.43, 3.24)].</p><p><strong>Conclusion: </strong>Selenium supplementation can increase selenium levels in HD patients, without notable impacts on weight, triglycerides, and total cholesterol.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnic diversity and urolithiasis: a single-center experience.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-03 DOI: 10.1007/s11255-025-04387-4
Kamran Hassan Bhatti, Rawa Bapir, Faaz Salah Gomha, Berun A Abdalla, Nadeem Sohail, Fattah H Fattah, Bnar Sardar Saida, Ahmed H A Shaat, Bryar Othman Muhammed, Khalid Mohammed Abdelrahman, Karukh K Mohammed, Shaima Q Abdalla, Hero Kh Mala, Dyari Q Hamad, Hiwa O Abdullah, Fahmi H Kakamad
{"title":"Ethnic diversity and urolithiasis: a single-center experience.","authors":"Kamran Hassan Bhatti, Rawa Bapir, Faaz Salah Gomha, Berun A Abdalla, Nadeem Sohail, Fattah H Fattah, Bnar Sardar Saida, Ahmed H A Shaat, Bryar Othman Muhammed, Khalid Mohammed Abdelrahman, Karukh K Mohammed, Shaima Q Abdalla, Hero Kh Mala, Dyari Q Hamad, Hiwa O Abdullah, Fahmi H Kakamad","doi":"10.1007/s11255-025-04387-4","DOIUrl":"https://doi.org/10.1007/s11255-025-04387-4","url":null,"abstract":"<p><p>Despite the diversity in the prevalence and risk factors of urolithiasis across different geographic regions, limited information exists among various ethnic groups of the same population. This study investigates the prevalence of kidney stones (KSs) among different ethnicities in a single center in Qatar and the risk factors associated with KS formation. This retrospective cross-sectional study was on Qatari residents who visited Al-Khor Hospital between January 1, 2014 and December 31, 2019. All adult permanent residents who presented with KSs or visited the hospital for general check-ups and for whom the required data were available were included. There was a highly significant difference in KS prevalence among ethnicities (p-value < 0.001). The Egyptians had the highest prevalence of KSs (78.5%), followed by Qataris (65.0%), Palestinians (63.5%), Bangladeshis (59.4%), Syrians (55.9%), Jordanians (53.8%), and Yemenis (53.5%). However, no significant difference was found when comparing the different races regarding urolithiasis (p-value = 0.19). Individuals with hypertension and diabetes mellitus had a significantly higher prevalence of KSs (p-value = 0.001). Among patients with prior renal surgery and positive family history, 59.9% and 70.5% had KSs, compared to 49.1% and 48.3% without previous surgery and negative family history (p-values = 0.002 and < 0.001, respectively). Smoking, poor dietary intake, alcohol consumption, and severe exposure to sunlight were significantly associated with KSs (p-value < 0.001). Urolithiasis among the Qatari population is multifactorial and shows variation based on ethnicity, with natives being the second most frequently affected group.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening tool for sarcopenia (SARC-F) predicts unsatisfactory medical treatment of lower urinary tract symptoms in elderly men aged 75 years or older: a preliminary observational study. 肌肉疏松症筛查工具(SARC-F)可预测 75 岁或以上老年男性下尿路症状治疗效果不理想的情况:一项初步观察研究。
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-01 Epub Date: 2024-10-17 DOI: 10.1007/s11255-024-04233-z
Naoki Wada, Tsubasa Hatakeyama, Haruka Takagi, Shun Morishita, Ryoken Tsunekawa, Masaya Nagabuchi, Takeya Kitta, Hidehiro Kakizaki
{"title":"Screening tool for sarcopenia (SARC-F) predicts unsatisfactory medical treatment of lower urinary tract symptoms in elderly men aged 75 years or older: a preliminary observational study.","authors":"Naoki Wada, Tsubasa Hatakeyama, Haruka Takagi, Shun Morishita, Ryoken Tsunekawa, Masaya Nagabuchi, Takeya Kitta, Hidehiro Kakizaki","doi":"10.1007/s11255-024-04233-z","DOIUrl":"10.1007/s11255-024-04233-z","url":null,"abstract":"<p><p>We investigated the influence of sarcopenia on treatment outcomes in elderly patients receiving medical therapy for lower urinary tract symptoms (LUTS). We included male patients with LUTS aged ≥ 75 years who had not changed their medication for 1 year. Current conditions were estimated using IPSS, overactive bladder symptoms score (OABSS), and screening tool for sarcopenia (SARC-F). We also evaluated prostatic volume (PV), serum testosterone level, grip strength, and nutrition status. SARC-F score of ≧4 was defined as sarcopenia. We included 59 patients in this study, including 16 patients (27.1%) with sarcopenia. The mean grip strength was significantly lower in the sarcopenia group than the non-sarcopenia group (25.5 vs. 30 kg, p < 0.01). IPSS total score, voiding symptom score of IPSS, and IPSS-QOL were significantly higher in the sarcopenia group than the non-sarcopenia group. The non-sarcopenia group had significantly larger PV (40 vs. 20 ml, p < 0.01) and higher testosterone levels (497.5 vs. 369 ng/ml, p = 0.03) compared with the sarcopenia group, whereas the percentage of patients taking dutasteride tended to be higher in the non-sarcopenia group than the sarcopenia group (58.1% vs. 31.3%, p = 0.07). Moderate and severe LUTS (IPSS total ≥ 8) persisted in 34 patients (57.6%) after medical treatment. Multivariate analysis showed that only SARC-F was a significant factor affecting the IPSS total ≥ 8 despite medical treatment for 1 year (OR 1.67, 95%CI: 1.13-2.46, p = 0.01). Sarcopenia defined by using SARC-F is a significant factor for unsatisfactory medical treatment of LUTS in elderly men aged ≥ 75 years.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":"399-406"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor Re: Low-frequency bladder vibration for the treatment of urinary tract infections in spinal cord injury patients with neurogenic bladder by Zhang et al.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-01 DOI: 10.1007/s11255-025-04393-6
Chike J Okeke, Shahid Siddique, Rauf N Khadr, Michael S Floyd
{"title":"Letter to the Editor Re: Low-frequency bladder vibration for the treatment of urinary tract infections in spinal cord injury patients with neurogenic bladder by Zhang et al.","authors":"Chike J Okeke, Shahid Siddique, Rauf N Khadr, Michael S Floyd","doi":"10.1007/s11255-025-04393-6","DOIUrl":"https://doi.org/10.1007/s11255-025-04393-6","url":null,"abstract":"","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic factors in T1 high-grade urothelial carcinoma of the bladder with lymphovascular invasion: a retrospective cohort study.
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-01 DOI: 10.1007/s11255-025-04391-8
Yajun Li, Xiaoyu Sun, Yue Wang, Baojie Ma, Changyi Quan
{"title":"Prognostic factors in T1 high-grade urothelial carcinoma of the bladder with lymphovascular invasion: a retrospective cohort study.","authors":"Yajun Li, Xiaoyu Sun, Yue Wang, Baojie Ma, Changyi Quan","doi":"10.1007/s11255-025-04391-8","DOIUrl":"https://doi.org/10.1007/s11255-025-04391-8","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the long-term treatment outcomes of T1 high-grade (T1HG) urothelial carcinoma (UCB) with lymphovascular invasion (LVI).</p><p><strong>Methods: </strong>We retrospectively analyzed the data of 70 patients of T1HG UCB with LVI who were treated at the Second Hospital of Tianjin Medical University between 2009 and 2019. The log rank test and Cox regression analyses were performed to identify factors that predict the recurrence and survival of these \"highest risk\" group of non-muscle invasive bladder cancer (NMIBC).</p><p><strong>Results: </strong>With a median follow-up of 46.0 months (range 2-151), the 5-year overall survival (OS), cancer-specific survival (CSS), recurrence-free survival (RFS) and progression-free survival (PFS) rates were 65%, 78%, 28% and 56% after trans-urethral resection of bladder tumor (TURBT), and 35%, 48%, 35% and 35% after radical cystectomy (RC), respectively. Treatment modality (tumor burden) was and independent predictor of OS (Hazard ratios (HRs) 2.176, 95% confidence intervals (CIs) 1.021-4.637, p = 0.044) and CSS (HRs 3.675, CIs 1.311-10.297, p = 0.013), and was weakly associated with RFS (HRs 0.560, CIs 0.281-1.114, p = 0.099). A history of urothelial carcinoma of the bladder (H.UCB) was an independent predictor of RFS (HRs 2.246, CIs 1.102-4.579, p = 0.026) and PFS (HRs 2.259, CIs 1.036-4.927, p = 0.041). Tumor size was an independent predictor of RFS (HRs 2.093, CIs 1.054-4.159, p = 0.035).</p><p><strong>Conclusions: </strong>In T1HG UCB with LVI, tumor burden was a significant predictor of survival. Radical cystectomy should be individualized and not universally recommended. Recurrent T1HG UCB with LVI potentially represents a sign of progression, and RC regardless of tumor burden might be a reasonable alternative for this subgroup of patients.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the suturing technique (barbed continuous versus conventional interrupted) impact the outcome of anastomotic urethroplasty? 缝合技术(带刺连续缝合与传统间断缝合)会影响吻合口尿道成形术的效果吗?
IF 1.8 4区 医学
International Urology and Nephrology Pub Date : 2025-02-01 Epub Date: 2024-10-09 DOI: 10.1007/s11255-024-04223-1
Yunus Çolakoğlu, Deniz Noyan Özlü, Ali Ayten, Metin Savun, Abdulmuttalip Simsek
{"title":"Does the suturing technique (barbed continuous versus conventional interrupted) impact the outcome of anastomotic urethroplasty?","authors":"Yunus Çolakoğlu, Deniz Noyan Özlü, Ali Ayten, Metin Savun, Abdulmuttalip Simsek","doi":"10.1007/s11255-024-04223-1","DOIUrl":"10.1007/s11255-024-04223-1","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and compare continuous suture (CS) and interrupted suture (IS) techniques applied in excision and primary anastomosis (EPA) urethroplasty in terms of surgical success and complication rates.</p><p><strong>Methods: </strong>A retrospective evaluation was conducted on patients with bulbar urethral strictures measuring ≤ 2.5 cm who underwent EPA between April 2020 and December 2022. Patients with a history of urethral reconstruction, multiple strictures, a history of pelvic radiotherapy, a diagnosis of Lichen sclerosis, a history of surgery due to congenital penile curvature or Peyronie's disease, and a follow-up period of less than 12 months were excluded. The patients were divided into two groups according to the suture technique used (CS or IS), and the groups were compared for demographic and perioperative data.</p><p><strong>Results: </strong>A total of 97 patients (CS n = 52, IS n = 55) were included in the sample. The mean age of the entire patient group was calculated to be 56.2 years and the mean stricture length was 19.3 mm. Operation time and postoperative catheter time were shorter in the CS group (94.7 ± 7.3 vs. 117.2 ± 5.7 min and 9.9 ± 1.6 vs. 15.8 ± 1.9 min, p < 0.001, respectively). The groups were similar regarding anatomical success, stress urinary incontinence, penile numbness, curvature, and postoperative infection (p > 0.05).</p><p><strong>Conclusion: </strong>No significant difference was observed in terms of success or complications between the CS and IS techniques employed during EPA urethroplasty. However, in addition to reducing the operation time, the CS technique offers the advantage of safely removing the urethral catheter earlier.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":"363-369"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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