International Urology and Nephrology最新文献

{"title":"Correction: Factors affecting the need for ureteral catheterization in symptomatic pregnancy hydronephrosis.","authors":"Osman Gercek, Kutay Topal, Veli Mert Yazar, Arif Demirbas","doi":"10.1007/s11255-026-05133-0","DOIUrl":"https://doi.org/10.1007/s11255-026-05133-0","url":null,"abstract":"","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147716718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The genitourinary phenotype of COVID: a personal perspective.","authors":"Michael B Chancellor","doi":"10.1007/s11255-026-05078-4","DOIUrl":"https://doi.org/10.1007/s11255-026-05078-4","url":null,"abstract":"","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147716759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and kidney outcomes in children with posterior urethral valve: a single-center experience.","authors":"Sibel Inceoğlu, Diana Uçkardeş, Nilüfer Göknar","doi":"10.1007/s11255-026-05149-6","DOIUrl":"https://doi.org/10.1007/s11255-026-05149-6","url":null,"abstract":"<p><strong>Introduction and aim: </strong>Posterior urethral valve (PUV) represent a congenital obstructive uropathy, and despite advances in prenatal diagnosis and postnatal management, chronic kidney disease (CKD) develops in nearly 20% of affected patients. The aim of this study is to determine the clinical characteristics and kidney outcomes in children with PUV.</p><p><strong>Materials and methods: </strong>A total of 52 boys followed with a diagnosis of posterior urethral valves were retrospectively evaluated. Data regarding antenatal diagnosis, age at admission, and timing of cystoscopic diagnosis were recorded. Clinical and laboratory data, including serum creatinine levels and glomerular filtration rate, ultrasonographic findings, urodynamic study results, DMSA findings, and voiding cystourethrography results, were collected. In addition, lower urinary tract symptoms and the frequency of lower urinary tract infections were documented.</p><p><strong>Findings: </strong>The mean age of the 52 patients was 9.8 ± 4.8 years, and the mean age at diagnosis was 28 ± 41 months. Antenatal diagnosis was present in 32 patients (64%) and CKD developed in 10 patients (19.2%). There was no significant difference in antenatal diagnosis rates between patients with and without CKD. In the non-CKD group, hydronephrosis grades decreased significantly at the last follow-up compared with baseline, whereas no significant improvement was observed in the CKD group. These patients had more severe and persistent hydronephrosis at final evaluation. Patients with CKD had higher ratios of increased bladder wall thickness and renal echogenicity at baseline and ureteral dilatation at final follow-up. In the baseline renal function model, baseline GFR was independently associated with CKD, but proteinuria did not retain statistical significance in multivariable analysis. There was no significant difference between groups regarding severe bladder dysfunction, DMSA renal scarring, vesicoureteral reflux grades, recurrent urinary tract infections, or incontinence.</p><p><strong>Conclusion: </strong>Our findings suggest that renal damage in children with PUV may begin during the antenatal period. In this cohort, postnatal factors such as bladder dysfunction, vesicoureteral reflux, and recurrent urinary tract infections were not significantly associated with CKD. Persistent hydronephrosis at last follow-up was more commonly observed in children with CKD. In multivariable analysis, baseline renal function was significantly associated with CKD development.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147716805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial/ethnic differences in time to nephrectomy and its association with cancer-specific mortality in localized renal cell carcinoma.","authors":"Maximilian Filzmayer, Federico Polverino, Michele Petix, Leonardo Quarta, Filippo Orlandi, Jordan A Goyal, Nicola Longo, Gennaro Musi, Alberto Briganti, Salvatore Micali, Shahrokh F Shariat, Marina Kosiba, Clara Humke, Mike Wenzel, Fred Saad, Felix K-H Chun, Pierre I Karakiewicz","doi":"10.1007/s11255-026-05141-0","DOIUrl":"https://doi.org/10.1007/s11255-026-05141-0","url":null,"abstract":"<p><strong>Purpose: </strong>Whether racial/ethnic differences exist in time to nephrectomy (TTN) and whether prolonged TTN differentially affects cancer-specific mortality (CSM) remains unclear. We evaluated race/ethnicity as a predictor of prolonged TTN and assessed race/ethnicity-specific associations between TTN and CSM in localized renal cell carcinoma (RCC).</p><p><strong>Methods: </strong>Patients were identified within the Surveillance, Epidemiology and End Results database (2010-2021) and stratified according to race/ethnicity and TTN ≤ 3 vs. > 3 months. Multivariable logistic regression models, propensity score matching (PSM) and multivariable competing risks regression models were used.</p><p><strong>Results: </strong>In 11,058 T1b-2 N0 M0 clear-cell RCC patients, TTN > 3 months was recorded in 1168 (15.6%) of 7506 Caucasians, in 505 (23.6%) of 2138 Hispanics, in 180 (26.6%) of 676 African Americans, and in 118 (16.0%) of 738 Asians and Pacific Islanders (API). Hispanic (OR 1.80, p < 0.001) and African American (OR 2.10, p < 0.001) race/ethnicity independently predicted higher proportions of TTN > 3 months, compared to Caucasian. Over the study span, the proportion of patients with TTN > 3 months increased significantly in all four racial/ethnic groups (all p < 0.01). After PSM, TTN > 3 months was associated with higher CSM in Caucasians (sHR 1.57, p < 0.001) and in Hispanics (sHR 1.55, p = 0.046), but not in African Americans or APIs.</p><p><strong>Conclusion: </strong>In localized RCC patients treated with nephrectomy, TTN > 3 months became more prevalent over time in all four examined racial/ethnic groups. In Hispanics and African Americans, TTN > 3 months proportions were higher than in Caucasians and APIs. TTN > 3 months was independently associated with higher CSM in Caucasians and Hispanics, but not in African Americans and APIs.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid bedside microscopic leukocyte counting for the diagnosis of peritoneal dialysis-associated peritonitis: diagnostic accuracy compared with automated flow cytometry.","authors":"Luca Nardelli, Antonio Scalamogna, Giuseppe Garigali, Anna Sikharulidze, Matteo Abinti, Anxhela Hida, Sara Moscardino, Federico Alberici, Giuseppe Castellano","doi":"10.1007/s11255-026-05140-1","DOIUrl":"https://doi.org/10.1007/s11255-026-05140-1","url":null,"abstract":"<p><strong>Background: </strong>Peritoneal dialysis (PD)-related peritonitis remains a major cause of technique failure, morbidity, and mortality. Timely diagnosis is crucial, yet conventional white blood cell (WBC) quantification by flow cytometry (FCC) requires centralized laboratory processing, delaying treatment. This study aimed to validate a direct manual microscopic (DMC) method for bedside quantification of WBCs in peritoneal effluent as a rapid diagnostic alternative.</p><p><strong>Methods: </strong>In this single-center study, 40 PD patients underwent 250 paired WBC assessments between January 2024 and June 2025. Peritoneal effluent samples were analyzed by both DMC and FCC at peritonitis onset, during treatment follow-up, and in asymptomatic controls. Diagnostic performance was evaluated using Spearman's correlation, receiver operating characteristic analysis, and the Youden index, employing FCC as the reference standard (> 100 cells/μL).</p><p><strong>Results: </strong>Across all evaluations, DMC and FCC showed a strong correlation (ρ = 0.91, p < 0.0001). In patients evaluated for suspected peritonitis (n = 36), DMC achieved a sensitivity of 97.0% and specificity of 100% at a cut-off of 20 cells/20 HPFs (AUC = 0.99; 95% CI 0.98-1.00). During follow-up (n = 187), correlation remained high (ρ = 0.89, p < 0.0001), with sensitivity 97.2% and specificity 83.4% at 12 cells/20 HPFs (AUC = 0.97; 95% CI 0.95-0.99).</p><p><strong>Conclusion: </strong>DMC provides a reliable, rapid, and quantitative alternative to automated cytometry for diagnosing and monitoring PD-related peritonitis. Its simplicity, affordability, and bedside applicability make it particularly suitable for integration with home turbidity monitoring systems to improve timely peritonitis management.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reanalysis of LUNAR progression-free survival using reconstructed individual patient data: time-varying treatment effects.","authors":"Kenji Tanabe, Soichiro Yoshida, Motohiro Fujiwara, Wei Chen, Shugo Yajima, Hiroyuki Sato, Akihiro Hirakawa, Hiroshi Fukushima, Yosuke Yasuda, Hajime Tanaka, Hitoshi Masuda, Yasuhisa Fujii","doi":"10.1007/s11255-026-05142-z","DOIUrl":"https://doi.org/10.1007/s11255-026-05142-z","url":null,"abstract":"<p><strong>Purpose: </strong>To assess whether treatment effects in the LUNAR trial are time-varying and to contextualize a single hazard ratio (HR) using complementary, clinically interpretable summaries of when and for how long separation is supported by available information, in a secondary methodological reassessment.</p><p><strong>Methods: </strong>Individual patient data were reconstructed by digitalizing published progression-free survival (PFS) Kaplan-Meier (KM) curves. Proportional hazards (PH) were assessed, and treatment effects were summarized using Fleming-Harrington weighted log-rank tests, a piecewise Cox summary, and restricted mean survival time (RMST) at a priori horizons.</p><p><strong>Results: </strong>The reconstructed and published KM curves closely matched the trajectories, and the reconstructed Cox HR was consistent with the published HR. PH diagnostics suggested non-proportional hazards (global Schoenfeld test p = 0.001). The early-weighted Fleming-Harrington test showed the strongest separation (χ² = 22.0, p < 0.001), whereas the late-weighted test did not provide confirmatory evidence (χ² = 2.51, p = 0.110). RMST favored ¹⁷⁷Lu-PSMA plus stereotactic body radiotherapy (relative difference in RMST (%) at 12 and 24 months, 43.7 [95% confidence interval: 24.9-65.3] and 67.8 [33.5-111], respectively). However, late follow-up estimates became increasingly imprecise as risk sets decreased.</p><p><strong>Conclusion: </strong>This reconstruction-based, hypothesis-generating reanalysis supported the primary inference of PFS benefit while suggesting time-varying effects. Weighted tests, piecewise summaries, and RMST may provide interpretable complements to a single HR. Late follow-up interpretation remains uncertain because of sparse late risk sets and events.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative non-contrast CT-derived adiposity quantity and attenuation predict recurrence-free survival after nephrectomy for localized clear cell renal cell carcinoma.","authors":"Zhongwei Ma, Le Kang, Yanghuang Zheng, Meiwei Gong, Xiaoshan Li, Junhai Ma, Panfeng Shang","doi":"10.1007/s11255-026-05137-w","DOIUrl":"https://doi.org/10.1007/s11255-026-05137-w","url":null,"abstract":"<p><strong>Purpose: </strong>To assess whether preoperative non-contrast CT-derived adiposity quantity and attenuation are independently associated with recurrence-free survival (RFS) after surgery for localized clear cell renal cell carcinoma (ccRCC).</p><p><strong>Methods: </strong>We performed a single-center retrospective cohort study of adults with pathologically confirmed ccRCC who underwent upfront partial or radical nephrectomy and had preoperative non-contrast abdominal CT within 30 days. A single mid-L3 axial slice was segmented for subcutaneous (SAT) and visceral adipose tissue (VAT) using predefined thresholds (SAT-190 to -30 HU; VAT-150 to-50 HU). Adiposity indices were normalized by height squared (SATI, VATI), and mean SAT/VAT attenuation (HU) was recorded. RFS was defined as time from surgery to first documented local/regional recurrence or distant metastasis. Multi-variable Cox models were adjusted for age, sex, chronic disease history, tumor diameter, surgery type, and WHO/ISUP grade; continuous predictors were standardized (per 1-SD). Incremental prognostic performance beyond the clinicopathologic base model was assessed using Harrell's C-index.</p><p><strong>Results: </strong>Among 598 patients, 151 (25.3%) developed recurrence/metastasis. Higher SATI and VATI were associated with longer RFS in separate adjusted models (per 1-SD: SATI HR 0.55, 95% CI 0.44-0.68; VATI HR 0.63, 0.53-0.76). Higher (less negative) attenuation was associated with shorter RFS in separate adjusted models (SAT HU HR 1.29, 1.12-1.48; VAT HU HR 1.40, 1.21-1.60). In joint models, the SATI association remained robust, whereas VATI and VAT attenuation were attenuated. The apparent C-index of the clinicopathologic base model improved from 0.667 to 0.707 after adding SATI and to 0.713 after adding SATI + VATI.</p><p><strong>Conclusion: </strong>Routine preoperative non-contrast CT measures of adiposity quantity, and to a lesser extent attenuation, provide prognostic information for postoperative RFS in localized ccRCC. In this localized surgery-treated cohort, SATI was the most stable independent marker and modestly improved discrimination beyond clinicopathologic factors.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telemedicine-supported assisted home hemodialysis in elderly and multimorbid patients: a real-world cohort study in a public healthcare system.","authors":"Anna Zito, Paolo Ria, Maria Luisa Lefons, Vilma Martella, Silvia Matino, Giulia Fontò, Silvia Barbarini, Tiziana Rollo, Marcello Napoli, Antonio De Pascalis","doi":"10.1007/s11255-026-05115-2","DOIUrl":"https://doi.org/10.1007/s11255-026-05115-2","url":null,"abstract":"<p><strong>Purpose: </strong>The aging of the hemodialysis (HD) population and the growing burden of multimorbidity increasingly challenge the sustainability and equity of conventional in-center dialysis within publicly funded healthcare systems. Although home hemodialysis (HHD) may offer clinical and organizational advantages, its implementation remains limited among elderly and functionally dependent patients. We evaluated the real-world feasibility, retention, and system-level impact of a telemedicine-supported assisted-HHD (A-HHD) program aimed at broadening access to complex individuals. We performed a retrospective, descriptive observational cohort study including all patients enrolled in an A-HHD program within a public healthcare authority in Southern Italy from June 2018 to June 2025. In September 2023, a structured telemedicine platform enabling real-time remote monitoring and audiovisual supervision was integrated into routine care. We assessed epidemiological trends, patient complexity, vascular access patterns, dialysis prescription and delivered dose, treatment retention, causes of discontinuation, and transportation-related economic outcomes.</p><p><strong>Results: </strong>A total of 146 patients (mean age 79 ± 7 years) with substantial cardiovascular, metabolic, and respiratory comorbidity were treated. Central venous catheters were used in 64% of cases. Following early program expansion, annual incidence stabilized at approximately 20-25 patients, while prevalence steadily increased, exceeding 20 active patients per month. More than half of patients remained on therapy beyond 6 months. Despite shorter individual sessions, increased treatment frequency achieved a weekly standard Kt/V comparable to conventional in-center HD. Treatment discontinuation was predominantly related to mortality or clinical indications rather than program failure.</p><p><strong>Conclusion: </strong>Telemedicine-supported A-HHD represents a feasible and organizationally sustainable model capable of expanding equitable access to home-based dialysis while supporting organizational sustainability in public healthcare systems.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From association to intervention: rethinking post-nephrectomy care in the COVID-19 era.","authors":"Xiaohui Han, Keda Lu","doi":"10.1007/s11255-026-05128-x","DOIUrl":"https://doi.org/10.1007/s11255-026-05128-x","url":null,"abstract":"","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative outcomes following open radical cystectomy in the setting of locally advanced bladder cancer.","authors":"Pierluigi Russo, Nazario Foschi, Nicolò Lentini, Francesco Pio Bizzarri, Giuseppe Maioriello, Mauro Ragonese, Chiara Ciccarese, Roberto Iacovelli, Giuseppe Palermo, Marco Campetella, Carlo Gandi, Domenico Nigro, Francesco Rossi, Domenico Varacalli, Savio Domenico Pandolfo, Or Schubert, Filippo Gavi, Daniele Fettucciari, Maria Chiara Sighinolfi, Marco Racioppi, Emilio Sacco, Bernardo Rocco","doi":"10.1007/s11255-026-05127-y","DOIUrl":"https://doi.org/10.1007/s11255-026-05127-y","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the perioperative outcomes and long-term survivors between localized (organ-confined cT2N0M0) and locally advanced (cT3-4 and/or cN1-3,M0) bladder cancer in patients undergoing radical cystectomy and lymphadenectomy.</p><p><strong>Methods: </strong>We conducted a retrospective observational cohort study including 364 consecutive patients who underwent open RC with urinary diversion at a high-volume tertiary referral center between July 2016 and November 2024. Patients were stratified according to pathological stage into localized disease (pT0-T2N0) and locally advanced disease (pT3-T4 and/or N1). Perioperative outcomes were evaluated using multivariable regression models. Overall survival (OS) was analyzed with Cox regression and Kaplan-Meier estimates. Recurrence-free survival (RFS) and cancer-specific survival (CSS) were assessed using Fine-Gray competing-risks models. Propensity score matching (PSM) was performed as a sensitivity analysis.</p><p><strong>Results: </strong>Among 364 patients, 203 had localized and 161 had locally advanced BCa. Locally advanced disease was associated with greater intraoperative blood loss (β 230 ml, 95% CI 89.9-370.3) and longer operative time (β 16.5 min, 95% CI 2.6-30.3), but postoperative complication rates were similar between groups. With a median follow-up of 54.9 months in localized and 36.4 months in locally advanced BCa, locally advanced disease was associated with significantly worse oncologic outcomes. Multivariable analyses confirmed higher risks of overall mortality (HR 3.40, 95% CI 2.40-4.81), recurrence (sHR 5.12, 95% CI 3.45-7.59), and cancer-specific mortality (sHR 2.26, 95% CI 1.43-3.59). Results were consistent after PSM.</p><p><strong>Conclusion: </strong>This study showed that, compared with localized disease, RC for locally advanced BCa was associated with similar 30-day mortality and major complication rates, but worse oncological outcomes. These findings support the perioperative feasibility of surgery in selected patients with locally advanced disease while underscoring their persistently poorer cancer prognosis.</p>","PeriodicalId":14454,"journal":{"name":"International Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}