International Journal of Vascular Medicine最新文献_第7页

Effect of N-Acetylcysteine on Dyslipidemia and Carbohydrate Metabolism in STZ-Induced Diabetic Rats. n -乙酰半胱氨酸对stz诱导糖尿病大鼠血脂异常及碳水化合物代谢的影响。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2018-01-28 eCollection Date: 2018-01-01 DOI: 10.1155/2018/6428630

Anderson Kiyoshi Kaga, Pedro Octavio Barbanera, Nágilla Orleanne Lima do Carmo, Lucas Rodolfo de Oliveira Rosa, Ana Angélica Henrique Fernandes

{"title":"Effect of N-Acetylcysteine on Dyslipidemia and Carbohydrate Metabolism in STZ-Induced Diabetic Rats.","authors":"Anderson Kiyoshi Kaga, Pedro Octavio Barbanera, Nágilla Orleanne Lima do Carmo, Lucas Rodolfo de Oliveira Rosa, Ana Angélica Henrique Fernandes","doi":"10.1155/2018/6428630","DOIUrl":"https://doi.org/10.1155/2018/6428630","url":null,"abstract":"Background: Type 1 diabetes mellitus (T1DM) is characterized by insulin-deficient production leading to hyperglycemia, which is associated with diabetic complications such as cardiovascular diseases. Antioxidants have been proving a good alternative to diabetic complications, with N-acetylcysteine (NAC) having antioxidant characteristics. The aim of this study was to assess the effect of NAC on the lipid profile and the atherogenic index (AI) in streptozotocin- (STZ-) induced diabetic rats.Method: 32 male Wistar rats (60 days of age) weighting ±250 g were randomly distributed into four groups (n = 8): CTRL: control rats; CTRL+NAC: control rats treated with NAC; DM: diabetic rats; DM+NAC: diabetic rats treated with NAC. T1DM was induced using STZ (60 mg/kg, ip; single dose), and NAC (25 mg/kg/day) was administrated by gavage, for 37 days. The animals received chow and water ad libitum. After the experimental period, blood and cardiac tissue samples were collected to analyze energetic metabolism, lipid profile, and AI.Results: NAC decreased (p < 0.01) glycemia, energy intake, carbohydrate, and protein consumption in diabetic rats (DM+NAC), when compared with DM, while the alimentary efficiency was improved (p < 0.01) in treated diabetic rats (DM+NAC). Diabetic rats treated with NAC decreased (p < 0.01) lipid profile and AI in diabetic rats (DM+NAC) when compared to DM.Conclusion: NAC improves lipid profile and decreases AI in STZ-induced diabetic rats.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2018 ","pages":"6428630"},"PeriodicalIF":1.3,"publicationDate":"2018-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6428630","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36127280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Impact of Modified Transesophageal Echocardiography on Mortality and Stroke after Cardiac Surgery: A Large Cohort Study. 改良的经食管超声心动图对心脏手术后死亡率和卒中的影响:一项大型队列研究。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-09-11 DOI: 10.1155/2017/1857069

Wouter W Jansen Klomp, Carl G M Moons, Arno P Nierich, George J Brandon Bravo Bruinsma, Arnoud W J Van't Hof, Jan G Grandjean, Linda M Peelen

{"title":"Impact of Modified Transesophageal Echocardiography on Mortality and Stroke after Cardiac Surgery: A Large Cohort Study.","authors":"Wouter W Jansen Klomp, Carl G M Moons, Arno P Nierich, George J Brandon Bravo Bruinsma, Arnoud W J Van't Hof, Jan G Grandjean, Linda M Peelen","doi":"10.1155/2017/1857069","DOIUrl":"https://doi.org/10.1155/2017/1857069","url":null,"abstract":"The aim of this study was to investigate the impact of perioperative screening with modified transesophageal echocardiography (A-View method). We compared, in consecutive patients who underwent cardiac surgery between 2006 and 2014, 30-day mortality and in-hospital stroke incidence, operated either with perioperative modified TEE screening (intervention group) or only with conventional TEE screening (control group). Of the 8,605 study patients, modified TEE was applied in 1,391 patients (16.2%). Patients in the intervention group were on average older (71 versus 68 years, p < 0.001) and more often females (31.0% versus 28.0%, p < 0.001) and had a higher predicted mortality (EuroSCORE I: 5.9% versus 4.0%, p < 0.001). The observed 30-day mortality was 2.2% and 2.5% in both groups, respectively, with multivariable and propensity-score adjusted relative risks (RRs) of 0.70 (95% CI: 0.50-1.00, p = 0.05) and 0.67 (95% CI: 0.45-0.98, p = 0.04). In-hospital stroke was 2.9% and 2.1% in both groups, respectively, with adjusted RRs of 1.03 (95% CI: 0.73-1.45) and 1.01 (95% CI: 0.71-1.43). In patients undergoing cardiac surgery, use of perioperative screening for aortic atherosclerosis with modified TEE was associated with lower postoperative mortality, but not stroke, as compared to patients operated on without such screening.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"1857069"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/1857069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35556247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Protocol for Diagnosis and Management of Aortic Atherosclerosis in Cardiac Surgery Patients. 心脏手术患者主动脉粥样硬化的诊断和治疗方案。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-08-09 DOI: 10.1155/2017/1874395

Wouter W Jansen Klomp, George J Brandon Bravo Bruinsma, Arnoud W J Van 't Hof, Jan G Grandjean, Arno P Nierich

引用次数: 3

Dyslipidemia in Patients with a Cardiovascular Risk and Disease at the University Teaching Hospital of Yaoundé, Cameroon. 喀麦隆雅温得大学教学医院心血管疾病危险患者的血脂异常

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-01-09 DOI: 10.1155/2017/6061306

Vicky Jocelyne Ama Moor, Sylvie Ndongo Amougou, Sebastien Ombotto, Felicien Ntone, Doriane Edna Wouamba, Bernadette Ngo Nonga

{"title":"Dyslipidemia in Patients with a Cardiovascular Risk and Disease at the University Teaching Hospital of Yaoundé, Cameroon.","authors":"Vicky Jocelyne Ama Moor, Sylvie Ndongo Amougou, Sebastien Ombotto, Felicien Ntone, Doriane Edna Wouamba, Bernadette Ngo Nonga","doi":"10.1155/2017/6061306","DOIUrl":"10.1155/2017/6061306","url":null,"abstract":"Objective. To determine the frequency of lipid abnormalities in patients with a cardiovascular risk and disease at the University Teaching Hospital (UTH) of Yaoundé. Materials and Methods. We conducted a cross-sectional study from 1 March to 31 May 2015 at the UTH of Yaoundé. We included all patients seen in the outpatient department with a diagnosis of a cardiovascular disease or a risk factor for cardiovascular disease. Patients who accepted to participate in the study were asked to answer a questionnaire; after that a blood sample was taken for lipid profile. An informed consent was signed by all the participants and the study has received approval from the national ethic committee. Results. We recruited 264 patients of which 119 were men and 145 were women with a sex ratio of 0.82. Mean age was 61.36 years. The frequency of lipid profiles abnormalities was as follows: low HDL cholesterol (44.3%), hypertriglyceridemia (18.9%), high LDL cholesterol (3.8%), and high total cholesterol 3.4%). Hypertriglyceridemia was strongly associated with type 2 diabetes mellitus. Conclusion. Low levels of HDL cholesterol and hypertriglyceridemia are more prevalent in our study population. More studies are needed to confirm this finding in our environment.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 1","pages":"6061306"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47323323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ABO Gene Polymorphism and Thrombomodulin -33G>A Polymorphism Were Not Risk Factors for Myocardial Infarction in Javanese Men. ABO基因多态性和血栓调节蛋白-33G>A多态性不是爪哇男性心肌梗死的危险因素。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-07-24 DOI: 10.1155/2017/2943467

Mifetika Lukitasari, Ahmad Hamim Sadewa, Mohammad Saifur Rohman

{"title":"ABO Gene Polymorphism and Thrombomodulin -33G>A Polymorphism Were Not Risk Factors for Myocardial Infarction in Javanese Men.","authors":"Mifetika Lukitasari, Ahmad Hamim Sadewa, Mohammad Saifur Rohman","doi":"10.1155/2017/2943467","DOIUrl":"https://doi.org/10.1155/2017/2943467","url":null,"abstract":"Genetic factors contribute to about a half of coronary artery diseases. During the last several decades, some studies suggested that non-O blood group and thrombomodulin polymorphism -33G>A are the risk factors of coronary artery disease especially in Asia. There was no prior study in Indonesia regarding this issue. Hence, this study was designed to investigate the correlation of ABO polymorphism and thrombomodulin polymorphism -33G>A with the incidence of acute myocardial infarction (AMI). A total of 192 subjects were enrolled in this case control study. AMI patients were diagnosed based on World Health Organization criteria. Healthy patients were subjects with AMI risk factor without any sign and symptoms of AMI. Patients with diabetes mellitus, cancer, and arrhythmia were excluded from this study. Genotyping for both polymorphisms was performed by PCR RFLP methods. The result of this study suggested that ABO polymorphism and thrombomodulin polymorphism -33G>A were not risk factors of AMI, p = 0.727 and p = 0.699, respectively. Furthermore, the analysis to identify the synergy of these polymorphisms failed to prove their correlation with AMI (p = 0.118). Conclusively, this study showed that ABO polymorphism and thrombomodulin polymorphism -33G>A were not risk factors of AMI.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"2943467"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2943467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35322388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Role of Endoplasmic Reticulum Stress in Cardiovascular Disease and Exercise. 内质网应激在心血管疾病和运动中的作用。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-08-10 DOI: 10.1155/2017/2049217

Junyoung Hong, Kwangchan Kim, Jong-Hee Kim, Yoonjung Park

{"title":"The Role of Endoplasmic Reticulum Stress in Cardiovascular Disease and Exercise.","authors":"Junyoung Hong, Kwangchan Kim, Jong-Hee Kim, Yoonjung Park","doi":"10.1155/2017/2049217","DOIUrl":"https://doi.org/10.1155/2017/2049217","url":null,"abstract":"Endoplasmic reticulum (ER) stress, which is highly associated with cardiovascular disease, is triggered by a disturbance in ER function because of protein misfolding or an increase in protein secretion. Prolonged disruption of ER causes ER stress and activation of the unfolded protein response (UPR) and leads to various diseases. Eukaryotic cells respond to ER stress via three major sensors that are bound to the ER membrane: activating transcription factor 6 (ATF6), inositol-requiring protein 1α (IRE1α), and protein kinase RNA-like ER kinase (PERK). Chronic activation of ER stress causes damage in endothelial cells (EC) via apoptosis, inflammation, and oxidative stress signaling pathways. The alleviation of ER stress has recently been accepted as a potential therapeutic target to treat cardiovascular diseases such as heart failure, hypertension, and atherosclerosis. Exercise training is an effective nonpharmacological approach for preventing and alleviating cardiovascular disease. We here review the recent viewing of ER stress-mediated apoptosis and inflammation signaling pathways in cardiovascular disease and the role of exercise in ER stress-associated diseases.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"2049217"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2049217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35379686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 83

Relationship of Common Vascular Anatomy to Cannulated Catheters. 普通血管解剖与置管的关系。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-12-19 DOI: 10.1155/2017/5157914

Paul Gagne, Karun Sharma

{"title":"Relationship of Common Vascular Anatomy to Cannulated Catheters.","authors":"Paul Gagne, Karun Sharma","doi":"10.1155/2017/5157914","DOIUrl":"https://doi.org/10.1155/2017/5157914","url":null,"abstract":"Superficial veins of the upper extremity are the primary location for placement of peripheral IV catheters (PIVC). It is believed that a significant portion of PIVCs placed may cross or abut valves and branching veins or occlude a significant portion of the vein, limiting the ability to aspirate blood from the PIVC. Two separate clinical investigations using ultrasound were performed to understand the potential interaction between PIVCs and the vein lumen and the venous valves and branches of the superficial veins of the upper extremity. One study with 35 adult volunteers interrogated 210 vein segments where a PIV would likely be placed. A second pediatric study evaluated 35 vein segments central to indwelling PIVCs. The combined data from the two studies showed that over 80% of adult veins and 85% of pediatric veins can properly accommodate 20-gauge and 22-gauge PIVC, respectively. Venous valves are frequent findings, either immediately peripheral to branching veins or at periodic 5 to 7 cm points. Antegrade blood flow can be restricted by a placed PIVC, while retrograde flow is very likely to be restricted by venous valves. Together, these findings may explain the difficulty in reliable aspiration of blood from PIVC.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"5157914"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/5157914","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35802052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana. 循环血管生成生长因子在糖尿病患者外周动脉疾病和腿痛在加纳。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-12-27 DOI: 10.1155/2017/2390174

Kwame Yeboah, Jennifer A Agyekum, Eric Kyei Baafour, Daniel A Antwi, Afua B Adjei, Vincent Boima, Ben Gyan

{"title":"Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana.","authors":"Kwame Yeboah, Jennifer A Agyekum, Eric Kyei Baafour, Daniel A Antwi, Afua B Adjei, Vincent Boima, Ben Gyan","doi":"10.1155/2017/2390174","DOIUrl":"https://doi.org/10.1155/2017/2390174","url":null,"abstract":"Objective: Peripheral arterial disease (PAD) is a common complication of diabetes, associated with impairment in angiogenesis. Angiogenesis is regulated by angiogenic growth factors such as angiopoietin 1 (Ang-1), Ang-2, and vascular endothelial growth factor (VEGF). We studied the association between angiogenic growth factors versus PAD and exertional leg symptoms in diabetes patients in Ghana.Method: In this cross-sectional study, ankle-brachial index was measured with oscillometrically and exertional leg symptoms were screened with Edinburgh claudication questionnaire in 140 diabetes patients and 110 nondiabetes individuals. Circulating levels of Ang-1, Ang-2, and VEGF were measured with immunosorbent assay.Results: The prevalence of PAD and exertional leg pain was 16.8% and 24.8%, respectively. Compared to non-PAD participants, PAD patients had higher VEGF levels [85.8 (37.5-154.5) versus 57.7 (16.6-161.1) p = 0.032] and lower Ang-1 levels [31.3 (24.8-42.6) versus 40.9 (28.2-62.1), p = 0.017]. In multivariable logistic regression, patients with exertional leg pain had increased the odds of plasma Ang-2 levels [OR (95% CI): 2.08 (1.08-6.41), p = 0.036].Conclusion: Diabetes patients with PAD and exertional leg pain have imbalance in angiogenic growth factors, indicating impaired angiogenesis. In patients with exertional leg pains, Ang-2 may be an important biomarker.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"2390174"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2390174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35831978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study. 一项观察性研究:多配偶制与接受血管造影的男性冠状动脉疾病的风险

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-01-30 DOI: 10.1155/2017/1925176

Amin Daoulah, Amir Lotfi, Mushabab Al-Murayeh, Salem Al-Kaabi, Salem M Al-Faifi, Osama E Elkhateeb, Mohamed N Alama, Ahmad S Hersi, Ciaran M Dixon, Waleed Ahmed, Mohamed Al-Shehri, Ali Youssef, Ahmed Moustafa Elimam, Ayman S Abougalambou, Waheed Murad, Alawi A Alsheikh-Ali

{"title":"Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study.","authors":"Amin Daoulah, Amir Lotfi, Mushabab Al-Murayeh, Salem Al-Kaabi, Salem M Al-Faifi, Osama E Elkhateeb, Mohamed N Alama, Ahmad S Hersi, Ciaran M Dixon, Waleed Ahmed, Mohamed Al-Shehri, Ali Youssef, Ahmed Moustafa Elimam, Ayman S Abougalambou, Waheed Murad, Alawi A Alsheikh-Ali","doi":"10.1155/2017/1925176","DOIUrl":"https://doi.org/10.1155/2017/1925176","url":null,"abstract":"Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and the Middle East, but its association with CAD is not well defined. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period from April 1, 2013, to March 30, 2014. Of 1,068 enrolled patients, 687 were married men. Polygamy was reported in 32% of married men (1 wife: 68%, 2 wives: 19%, 3 wives: 10%, and 4 wives: 3%). When stratified by number of wives, significant baseline differences were observed in age, type of community (rural versus urban), prior coronary artery bypass grafting (CABG), and household income. After adjusting for baseline differences, there was a significant association between polygamy and CAD (adjusted OR 4.6 [95% CI 2.5, 8.3]), multivessel disease (MVD) (adjusted OR 2.6 [95% CI 1.8, 3.7]), and left main disease (LMD) (adjusted OR 3.5 [95% CI 2.1, 5.9]). Findings were consistent when the number of wives was analyzed as a continuous variable. In conclusion, among married men undergoing coronary angiography for clinical indications, polygamy is associated with the presence of significant CAD, MVD, and LMD.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"1925176"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/1925176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34775868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Maintenance of the Results of Stage II Lower Limb Lymphedema Treatment after Normalization of Leg Size. 腿部尺寸正常化后II期下肢淋巴水肿治疗结果的维持。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-08-01 DOI: 10.1155/2017/8515767

Jose Maria Pereira de Godoy, Henrique Jose Pereira de Godoy, Renata Lopes Pinto, Fernando Nestor Facio, Maria de Fatima Guerreiro Godoy

{"title":"Maintenance of the Results of Stage II Lower Limb Lymphedema Treatment after Normalization of Leg Size.","authors":"Jose Maria Pereira de Godoy, Henrique Jose Pereira de Godoy, Renata Lopes Pinto, Fernando Nestor Facio, Maria de Fatima Guerreiro Godoy","doi":"10.1155/2017/8515767","DOIUrl":"https://doi.org/10.1155/2017/8515767","url":null,"abstract":"Objective: The aim of this study was to identify strategies to transfer responsibility of the maintenance of the results of lymphedema treatment to the patient.Methods: Maintenance of the reduction of edema was evaluated in a prospective clinical trial in patients with Stage II leg lymphedema. Twenty-one lymphedematous lower limbs were evaluated in Clínica Godoy in 2014 and 2016. The evaluation was done by volumetry at baseline and weekly thereafter for volume control. Patients wore Venosan® cotton 20/30 and 30/40 mmHg elastic compression stockings followed by a custom-made inelastic stocking made of grosgrain fabric. The Friedman test for multiple comparisons and Conover post hoc test were used for statistical analysis with an alpha error of 5%.Results: On comparing leg volume changes using the different types of stockings, the 20/30 mmHg elastic compression stockings failed in the first week to maintain the volume reductions but the 30/40 mmHg compression stockings did not allow significant increases in volume (p value > 0.05). During one week, the grosgrain stocking reduced leg volumes to baseline values (p value = 0.24).Conclusion: Higher compression of elastic stockings is better than lower compression but the inelastic grosgrain stocking is even better than both to maintain the results.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"8515767"},"PeriodicalIF":1.3,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/8515767","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35442338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12