International Journal of Vascular Medicine最新文献

{"title":"Specialist Palliative Care Service Involvement and Prognostic Factors in Patients Presenting With Acute Limb Ischaemia to Waikato Hospital, Hamilton, New Zealand: A Retrospective Review.","authors":"Stacey Hooper, Stephanie Eckoldt, Stuart Brown, Jun Cheul Park, Manar Khashram","doi":"10.1155/ijvm/8163761","DOIUrl":"https://doi.org/10.1155/ijvm/8163761","url":null,"abstract":"<p><strong>Background: </strong>There is significant morbidity and mortality associated with acute limb ischaemia (ALI) and prognostication is complex. Current literature reports underutilisation of specialist palliative care (SPC) and lack of prognostic indicators to guide decision-making and referral.</p><p><strong>Objective/aim: </strong>The aim of this study is to review and analyse demographic, clinical and mortality data for a cohort of ALI patients to determine potential prognostic indicators, SPC referral patterns and SPC services received.</p><p><strong>Method: </strong>Retrospective clinical record reviews for a cohort of ALI patients referred to the Waikato Hospital Vascular Surgery team in a specified time period. This included laboratory, imaging and death documentation and functional status at baseline and ALI diagnosis.</p><p><strong>Results: </strong>One hundred fifty-five ALI patients were identified of whom 140 met the inclusion criteria. A 30-day mortality was 19% and 1-year mortality was 31% for the study cohort. Lactate > 2.2 mmol//L, albumin < 27 g/L Rutherford III staging and reduced functional capacity (Australia-modified Karnofsky Performance Scale score ≤ 50 at baseline and ≤ 40 at ALI diagnosis) were found to be independent predictors of mortality. Referral for SPC was 14% of the study cohort, usually late in the admission and often in the last few days of life. SPC provided a wide range of services, frequently exceeding the referral request.</p><p><strong>Conclusion: </strong>The four independent predictors of mortality could be used to identify ALI patients with a poor prognosis, encourage earlier referral for SPC, support appropriate symptom management and enable discussions on patient priorities.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"8163761"},"PeriodicalIF":0.7,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes Mellitus Duration and Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention: A Prospective Cohort Study.","authors":"Ayesha Tariq, Zohra Bhatti, Amer H Khan, Madeeha Laghari, Bandeh Ali Talpur, Muhammad Aamir, Khalid Hussain","doi":"10.1155/ijvm/8260099","DOIUrl":"10.1155/ijvm/8260099","url":null,"abstract":"<p><strong>Objective: </strong>This study is aimed at evaluating the impact of Type 2 diabetes mellitus (T2DM) duration on major adverse cardiovascular events (MACEs) after percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>A single-center prospective cohort study was conducted in which 465 T2DM patients undergoing PCI and completing the 1-year follow-up were enrolled. Patients were divided into three groups based on duration of DM: < 5 years, 5-10 years, and > 10 years. The primary endpoint was MACE, a composite of nonfatal myocardial infarction (MI), stroke, coronary artery bypass grafting (CABG), repeat PCI, and mortality.</p><p><strong>Results: </strong>The incidence of MACE increased progressively with longer diabetes duration: 3.7% (< 5 years), 8.1% (5-10 years), and 13.9% (> 10 years), with particularly higher rates of stroke (0.6%-3.0%) and repeat PCI (1.8%-6.0%) among T2DM patients after PCI. The Kaplan-Meier analysis demonstrated a clear stepwise rise in cumulative MACE incidence over 12 months, with the highest event rates observed in patients with diabetes for more than 10 years (log-rank <i>p</i> < 0.004). Consistently, Cox proportional hazards models showed significantly elevated risk compared with the < 5-year group, with adjusted hazard ratios of 3.16 (95% CI: 1.06-9.47, <i>p</i> = 0.039) for 5-10 years and 4.37 (95% CI: 1.59-12.01, <i>p</i> = 0.004) for > 10 years.</p><p><strong>Conclusion: </strong>Patients with longer duration (> 10 years) of T2DM had the highest incidence and hazard of adverse cardiovascular events compared to shorter duration (< 5 years and 5-10 years). These results suggest that targeted preventive strategies and closer post-PCI monitoring are essential for patients with prolonged diabetes duration.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"8260099"},"PeriodicalIF":0.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13531459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profiles of Hospitalized Middle Eastern Patients With Nonvalvular Atrial Fibrillation: Analysis From the JoFib Study.","authors":"Abdullah Al-Kasasbeh, Ahmad Abdalmajeed Alghzawi, Amr Alfakhouri, Nazih Kadri, Ammar Aloqaily, Mohammad Al-Oakily, Baha Awad, Ayman J Hammoudeh","doi":"10.1155/ijvm/6426995","DOIUrl":"10.1155/ijvm/6426995","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is the most prevalent sustained arrhythmia and is associated with significant morbidity and mortality. Data on AF in hospitalized patients in the Middle East are limited.</p><p><strong>Methods: </strong>We analyzed 536 hospitalized patients with nonvalvular AF from the Jordan atrial fibrillation (JoFib) registry. A prospective multicenter study of 2020 patients enrolled between May 2019 and December 2020. Patients were stratified into new-onset atrial fibrillation (NOAF) and previously diagnosed AF, and their clinical characteristics and in-hospital outcomes were compared.</p><p><strong>Results: </strong>The cohort had a mean age of 70.2 ± 14.1 years, and 48.7% were male. The most common comorbidities were hypertension (77.6%), diabetes (52.1%), and heart failure (31.3%). NOAF patients were significantly younger and more likely to be smokers, whereas those with prior AF had more comorbidities and larger left atrial size. Overall, in-hospital mortality was 6.7% but was significantly higher in NOAF patients.</p><p><strong>Conclusions: </strong>Hospitalized patients with NOAF are younger, more often smokers, and face higher in-hospital mortality compared with chronic AF, underscoring the need for early recognition and risk factor modification to prevent hospitalization.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT03917992.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"6426995"},"PeriodicalIF":0.7,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midterm Outcomes of Endovascular-First Revascularization for Multilevel Peripheral Arterial Disease With Chronic Limb-Threatening Ischemia: A Retrospective Study From Vietnam.","authors":"Lam Van Nut, Trinh Vu Nghia","doi":"10.1155/ijvm/5524641","DOIUrl":"10.1155/ijvm/5524641","url":null,"abstract":"<p><strong>Background: </strong>Peripheral arterial disease (PAD) with chronic limb-threatening ischemia (CLTI) represents advanced systemic atherosclerosis and carries high risks of amputation and mortality. Multilevel arterial involvement is common and often requires revascularization of both inflow and outflow segments. However, midterm outcome data in Vietnam remain limited.</p><p><strong>Objectives: </strong>This study is aimed at evaluating midterm clinical outcomes and identifying factors associated with wound healing, all-cause mortality, and major limb amputation after an endovascular-first revascularization strategy for multilevel PAD with CLTI.</p><p><strong>Methods: </strong>This retrospective case series included 91 patients with multilevel PAD (≥ 2 anatomical levels according to TASC II) and CLTI (Rutherford 4-6) treated at a tertiary hospital in Vietnam from 2017 to 2019. Patients were followed for 24 months. Kaplan-Meier analysis was used to describe survival, limb salvage, and wound healing over 24 months. Univariable and multivariable logistic regressions were used to identify factors associated with fixed-time binary outcomes within 24 months, including wound healing, mortality, and major limb amputation.</p><p><strong>Results: </strong>The mean age was 74.0 ± 11.6 years, and 82.4% were male. The ankle-brachial index improved significantly after intervention (0.2 vs. 0.5; <i>p</i> < 0.001). The mean follow-up duration was 18.9 ± 8.3 months. At 24 months, mortality was 27.5%, major amputation occurred in 18.7% (limb salvage 81.3%), and 62.2% of patients with tissue loss achieved wound healing (median 5 months). Age ≥ 75 years and neutrophil-to-lymphocyte ratio ≥ 3.5 were independently associated with reduced wound healing. Wound healing was associated with lower mortality and amputation risk. Adjunctive open surgery reduced limb amputation.</p><p><strong>Conclusion: </strong>An endovascular-first revascularization strategy for multilevel PAD with CLTI achieved acceptable midterm limb salvage and wound healing, although mortality remained considerable. Risk stratification and multimodal care are essential to improve outcomes.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"5524641"},"PeriodicalIF":0.7,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13442587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial Stiffness and Cognitive Impairment in Patients With Arterial Hypertension: CAVI and haSTART Index.","authors":"T A Safronova, S E Mukhanova, T S Vargina, A I Tarzimanova, A E Pokrovskaya, E R Konchenko, A G Cherepanov, V I Podzolkov","doi":"10.1155/ijvm/9456777","DOIUrl":"10.1155/ijvm/9456777","url":null,"abstract":"<p><strong>Introduction: </strong>Increased arterial stiffness is recognized as one of the established risk factors for cardiovascular diseases (CVDs), including the onset of cognitive impairment (CogI) and vascular dementia.</p><p><strong>Aim: </strong>The objective of our study was to investigate the relationship between the cardio-ankle vascular index (CAVI) and the STELARI heart-ankle STiffness of ARTeries (haSTART) index in patients diagnosed with arterial hypertension (HTN) devoid of comorbidities. The secondary aim of the study was to explore the association of these indices with CI in patients with HTN.</p><p><strong>Methods: </strong>Arterial stiffness was assessed using CAVI and the haSTART index. Cognitive status of all patients was obtained via the Montreal Cognitive Assessment (MoCA).</p><p><strong>Results: </strong>A total cohort of 128 patients (55 men and 73 women, aged 35-79 years) was incorporated into the single-center study, comprising 96 subjects with essential HTN (Group 1) and 32 with no HTN in history (Group 2-controls). A robust correlation was observed upon examining CAVI and the haSTART index in all subjects (<i>r</i> = 0.977, <i>p</i> < 0.001). Moreover, significant correlations were identified between the MoCA results and CAVI (<i>r</i> = -0.502, <i>p</i> = 0.001) and the haSTART index (<i>r</i> = -0.512, <i>p</i> = 0.001).</p><p><strong>Conclusion: </strong>The results of the study indicated a relationship between arterial stiffness and CI, as evidenced by the association between CAVI and MoCA results. Furthermore, we identified for the first time a correlation between the haSTART index and MoCA, thereby reflecting the association between arterial stiffness and CI.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"9456777"},"PeriodicalIF":0.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13409031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Cardiovascular Response to Acute Hypotension in Heart Failure Patients Compared to Healthy Adults.","authors":"Chelsea N Cady, Soraya M Samii, Cheryl A Blaha, Michael J White, Lawrence I Sinoway, Rachel C Drew","doi":"10.1155/ijvm/5472750","DOIUrl":"10.1155/ijvm/5472750","url":null,"abstract":"<p><p>Heart failure (HF) patients exhibit autonomic dysfunction. Orthostatic hypotension occurs often in HF and may be linked with altered cardiovascular responsiveness in HF. However, the cardiovascular response to acute hypotension in HF patients compared to healthy adults is unknown. Therefore, data were retrospectively analysed from eight patients with HF with reduced ejection fraction (7 male/1 female) and seven healthy adults (CON; 6 male/1 female) who underwent acute hypotension via thigh cuff deflation following 7.5 min of unilateral lower limb occlusion. Mean arterial blood pressure (MAP; photoplethysmogram) and heart rate (HR; electrocardiogram) were continuously recorded. Statistical analysis involved independent-samples <i>t</i>-tests. Baseline cardiovascular values were not different between groups (all <i>p</i> > 0.05). The magnitudes of the MAP peak decrease during acute hypotension and consequent HR peak increase were not different between groups (MAP: HF -11 ± 3 mmHg vs. CON -12 ± 5 mmHg, <i>p</i> = 0.756; HR: HF 3 ± 2b · min^-1 vs. CON 4 ± 3b · min^-1, <i>p</i> = 0.243). However, the MAP time to peak decrease and HR time to peak increase were longer in HF than CON (MAP: HF 11 ± 5 s vs. CON 6 ± 3 s, <i>p</i> = 0.041; HR: HF 10 ± 4 s vs. CON 6 ± 2 s, <i>p</i> = 0.044). HF patients exhibit a delayed cardiovascular response to acute hypotension compared to healthy adults, which may be linked with more frequent orthostatic hypotension in HF.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"5472750"},"PeriodicalIF":0.7,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13355312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148421065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review of the Effectiveness of Assessing Skin Changes for Chronic Venous Insufficiency in People With Dark Skin Tones and the Impact on the Patient Journey and Clinical Care.","authors":"Victoria J Clemett, Jemell Geraghty, Neesha Oozageer Gunowa, Sue Woodward, Tesfamariam Aklilu Betemariam, Audrey Edomobi, Alice Milsom, Toby Prevost, Riana John, Lukla Biasi","doi":"10.1155/ijvm/8034303","DOIUrl":"10.1155/ijvm/8034303","url":null,"abstract":"<p><strong>Aims: </strong>This review is aimed at systematically identifying, evaluating and synthesising the influence skin tone has on patient assessment and patient journey in people with chronic venous insufficiency.</p><p><strong>Background: </strong>Chronic venous disease of the lower limb typically presents with cutaneous manifestations that differ across skin tones. However, its impact on patient assessment and patient journey is unknown.</p><p><strong>Design: </strong>This systematic review and evidence synthesis were conducted following a protocol prospectively registered in PROSPERO (CRD42023459310) and reported using the PRISMA 2020 guideline.</p><p><strong>Methods: </strong>Primary research studies, quality improvement projects or case reports published in English up to February 2025 were included. Screening, data extraction and quality appraisal were undertaken independently by two authors. As skin tone was rarely reported, ethnicity or race was used as a proxy, introducing a misclassification risk. Meta-analysis compared clinical classifications on CEAP, and other data were discussed narratively.</p><p><strong>Data sources: </strong>Data sources include MedLine, Excerpta Medica Database (EMBASE), Cumulated Index of Nursing and Allied Health Literature (CINAHL), British Nursing Index (BNI), Scopus and registries of ongoing studies (ISRCTN registry and ClinicalTrials.gov).</p><p><strong>Results: </strong>Twenty-two studies were included involving 111,090 individuals. Findings indicate that people of Black and Thai ethnicities may have pathophysiological changes associated with venous disease without some or all the clinical presentations of venous insufficiency. It is hypothesised that this contributes to people with dark skin tones not receiving timely vascular care and appropriate management in the early stages of venous hypertension. However, insufficient reporting on skin tone limits the interpretation of findings.Evidence suggests treatment disparities across ethnic groups, with people of Black ethnicity having higher treatment costs, more interventions and the least improvements following interventions. However, the contribution of skin tone and clinical presentation remains unclear due to a lack of qualitative data and the influence of other covariables, such as health-seeking behaviours and compression use.</p><p><strong>Conclusions: </strong>Visible varicose veins appear to be unreliable indicators of venous disease, which may contribute to diagnostic challenges and health inequity. However, improved skin tone reporting is needed to enable clinical presentation to be considered independently of the social constructs of ethnicity.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"8034303"},"PeriodicalIF":0.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148329699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Activin A Level and 1-Year Mortality in Atrial Septal Defect-Associated Pulmonary Artery Hypertension: A Case-Control Study From the COHARD-PH Registry.","authors":"Pranindya Rinastiti, Anggoro Budi Hartopo, Cindy Elica Cipta, Syallom Gita Maharani, Dyah Wulan Anggrahini, Noriaki Emoto, Lucia Kris Dinarti","doi":"10.1155/ijvm/7787559","DOIUrl":"10.1155/ijvm/7787559","url":null,"abstract":"<p><strong>Background: </strong>Serum activin A level is a promising prognostic biomarker for pulmonary artery hypertension (PAH). In this study, we aim to investigate serum activin A levels and their associations with 1-year mortality in atrial septal defect (ASD)-associated PAH patients.</p><p><strong>Methods: </strong>This was a case-control study of adult Indonesian patients diagnosed with ASD-PAH from the COHARD-PH registry. Cases were subjects deceased in a 1-year follow-up, whereas controls were those survived. Serum activin A was measured at the index of diagnosis. The demographics, clinical parameters, hemodynamic, and mortality data were retrieved from the registry database up to a 1-year follow-up period. These data were compared and analyzed between the case and control groups.</p><p><strong>Results: </strong>From the 1-year follow-up data, 44 cases (deceased group) and 102 controls (survived group) were identified. The deceased group had significant lower bodyweight (<i>p</i> < 0.001), body mass index (BMI) (<i>p</i> < 0.01), with higher NT-proBNP level (< 0.0001), higher proportion of Eisenmenger syndrome (<i>p</i> < 0.05), higher right atrial (RA) area (<i>p</i> < 0.0001), lower tricuspid annular plane systolic excursion (TAPSE) (<i>p</i> < 0.01), and a significant increase in mean right atrial pressure (mRAP) (< 0.0001). There was no difference in the activin A level between deceased and survivors (506.3 ± 259.1 pg/mL vs. 536.1 ± 293.9 pg/mL, <i>p</i> > 0.05, respectively). Moreover, activin A level did not associate with the mortality risk among subjects (OR = 0.9996; 95% CI: 0.9982-1.00087; <i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Serum activin A level did not associate with 1-year mortality in adult patients with ASD-associated PAH.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"7787559"},"PeriodicalIF":0.7,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13200696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Sedentary Behaviour Reduction Programme in Patients With Peripheral Arterial Disease: A Mixed-Method Feasibility Study.","authors":"Marwa Said, Wael Tawfick, Charlotte L Edwardson, Marcia Carvalho, Sherif Sultan, Mahmoud Alawy, Eleftheria Filandrianou, Megan Nolan, Jennifer Jones","doi":"10.1155/ijvm/1159242","DOIUrl":"10.1155/ijvm/1159242","url":null,"abstract":"<p><strong>Background: </strong>People with peripheral arterial disease (PAD) have high levels of sedentary behaviour (SB), which contributes to declining mobility, poorer quality of life and increased cardiovascular risk; however, few studies have targeted reducing SB in this population.</p><p><strong>Objective: </strong>The study is aimed at evaluating the feasibility and acceptability of delivering and evaluating a 12-week remotely delivered intervention designed to reduce sedentary time in people with PAD.</p><p><strong>Methods: </strong>This was a single-arm, single-centre feasibility study in participants with PAD. The intervention combined online education, a wearable physical activity tracker and weekly coaching calls. At baseline and 12 weeks, SB and physical activity were measured with activPAL, functional capacity was assessed remotely using the Timed Walk app for the 6-min walk test and semistructured interviews were conducted at 12 weeks to evaluate acceptability.</p><p><strong>Results: </strong>Thirty participants provided consent (77% recruitment rate) and took part in the study, with 21 (70%) attending follow-up. Valid activPAL data at baseline and follow-up was provided by 18 participants (60% of those consented). At baseline, participants spent 63% of their waking day sitting (9.58 h/day), which was slightly lower at 12 weeks (60%). Qualitative analysis identified four themes covering awareness, motivation, engagement and barriers. Participants valued weekly calls and feedback on physical activity from the wearable.</p><p><strong>Conclusion: </strong>Overall, the intervention was feasible and acceptable, and data suggest that it may reduce sedentary time. Methods to enhance retention and compliance with the activPAL would be needed for a larger trial.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT05961943.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"1159242"},"PeriodicalIF":0.7,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model.","authors":"International Journal Of Vascular Medicine","doi":"10.1155/ijvm/9767252","DOIUrl":"10.1155/ijvm/9767252","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2014/254270.].</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2026 ","pages":"9767252"},"PeriodicalIF":1.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}