International Journal of Vascular Medicine最新文献_第10页

Children and Adolescent Obesity Associates with Pressure-Dependent and Age-Related Increase in Carotid and Femoral Arteries' Stiffness and Not in Brachial Artery, Indicative of Nonintrinsic Arterial Wall Alteration. 儿童和青少年肥胖与颈动脉和股动脉僵硬度的压力依赖性和年龄相关性增加有关，而与肱动脉无关，这表明动脉壁发生了非内在性改变。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2016-01-01 Epub Date: 2016-03-15 DOI: 10.1155/2016/4916246

Victoria García-Espinosa, Santiago Curcio, Juan Manuel Castro, Maite Arana, Gustavo Giachetto, Pedro Chiesa, Yanina Zócalo, Daniel Bia

{"title":"Children and Adolescent Obesity Associates with Pressure-Dependent and Age-Related Increase in Carotid and Femoral Arteries' Stiffness and Not in Brachial Artery, Indicative of Nonintrinsic Arterial Wall Alteration.","authors":"Victoria García-Espinosa, Santiago Curcio, Juan Manuel Castro, Maite Arana, Gustavo Giachetto, Pedro Chiesa, Yanina Zócalo, Daniel Bia","doi":"10.1155/2016/4916246","DOIUrl":"10.1155/2016/4916246","url":null,"abstract":"Aim. To analyze if childhood obesity associates with changes in elastic, transitional, and/or muscular arteries' stiffness. Methods. 221 subjects (4-15 years, 92 females) were assigned to normal weight (NW, n = 137) or obesity (OB, n = 84) groups, considering their body mass index z-score. Age groups were defined: 4-8; 8-12; 12-15 years old. Carotid, femoral, and brachial artery local stiffness was determined through systodiastolic pressure-diameter and stress-strain relationships. To this end, arterial diameter and peripheral and aortic blood pressure (BP) levels and waveforms were recorded. Carotid-femoral, femoropedal, and carotid-radial pulse wave velocities were determined to evaluate aortic, lower-limb, and upper-limb regional arterial stiffness, respectively. Correlation analysis between stiffness parameters and BP was done. Results. Compared to NW, OB subjects showed higher peripheral and central BP and carotid and femoral stiffness, reaching statistical significance in subjects aged 12 and older. Arterial stiffness differences disappeared when levels were normalized for BP. There were no differences in intrinsic arterial wall stiffness (elastic modulus), BP stiffness relationships, and regional stiffness parameters. Conclusion. OB associates with BP-dependent and age-related increase in carotid and femoral (but not brachial) stiffness. Stiffness changes would not be explained by intrinsic arterial wall alterations but could be associated with the higher BP levels observed in obese children. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2016 ","pages":"4916246"},"PeriodicalIF":1.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34392914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CT Angiography Analysis of Axillary Artery Diameter versus Common Femoral Artery Diameter: Implications for Axillary Approach for Transcatheter Aortic Valve Replacement in Patients with Hostile Aortoiliac Segment and Advanced Lung Disease. 腋窝动脉直径与股总动脉直径的CT血管造影分析:腋窝入路经导管主动脉瓣置换术对不良髂主动脉段和晚期肺部疾病患者的意义

IF 1.3

International Journal of Vascular Medicine Pub Date : 2016-01-01 Epub Date: 2016-03-27 DOI: 10.1155/2016/3610705

Rajiv Tayal, Humayun Iftikhar, Benjamin LeSar, Rahul Patel, Naveen Tyagi, Marc Cohen, Najam Wasty

{"title":"CT Angiography Analysis of Axillary Artery Diameter versus Common Femoral Artery Diameter: Implications for Axillary Approach for Transcatheter Aortic Valve Replacement in Patients with Hostile Aortoiliac Segment and Advanced Lung Disease.","authors":"Rajiv Tayal, Humayun Iftikhar, Benjamin LeSar, Rahul Patel, Naveen Tyagi, Marc Cohen, Najam Wasty","doi":"10.1155/2016/3610705","DOIUrl":"https://doi.org/10.1155/2016/3610705","url":null,"abstract":"Objective. The use of the axillary artery as an access site has lost favor in percutaneous intervention due to the success of these procedures from a radial or brachial alternative. However, these distal access points are unable to safely accommodate anything larger than a 7-French sheath. To date no studies exist describing the size of the axillary artery in relation to the common femoral artery in a patient population. We hypothesized that the axillary artery is of comparable size to the CFA in most patients and less frequently diseased. Methods. We retrospectively reviewed 110 CT scans of the thoracic and abdominal aorta done at our institution to rule out aortic dissection in which the right axillary artery, right CFA, left axillary artery, and left CFA were visualized. Images were then reconstructed using commercially available TeraRecon software and comparative measurements made of the axillary and femoral arteries. Results. In 96 patients with complete data, the mean sizes of the right and left axillary artery were slightly smaller than the left and right CFA. A direct comparison of the sizes of the axillary artery and CFA in the same patient yielded a mean difference of 1.69 mm ± 1.74. In all patients combined, the mean difference between the axillary artery and CFA was 1.88 mm on the right and 1.68 mm on the left. In 19 patients (19.8%), the axillary artery was of the same caliber as the associated CFA. In 8 of 96 patients (8.3%), the axillary artery was larger compared to the CFA. Conclusions. Although typically smaller, the axillary artery is often of comparable size to the CFA, significantly less frequently calcified or diseased, and in almost all observed cases large enough to accommodate a sheath with up to 18 French. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2016 ","pages":"3610705"},"PeriodicalIF":1.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/3610705","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34429120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Treatment of Intravenous Leiomyomatosis with Cardiac Extension following Incomplete Resection 静脉平滑肌瘤病不完全切除后心脏延伸的治疗

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-12-10 DOI: 10.1155/2015/756141

M. Doyle, Annette Li, C. Villanueva, S. Peeceeyen, M. Cooper, K. Hanel, G. Fermanis, G. Robertson

{"title":"Treatment of Intravenous Leiomyomatosis with Cardiac Extension following Incomplete Resection","authors":"M. Doyle, Annette Li, C. Villanueva, S. Peeceeyen, M. Cooper, K. Hanel, G. Fermanis, G. Robertson","doi":"10.1155/2015/756141","DOIUrl":"https://doi.org/10.1155/2015/756141","url":null,"abstract":"Aim. Intravenous leiomyomatosis (IVL) with cardiac extension (CE) is a rare variant of benign uterine leiomyoma. Incomplete resection has a recurrence rate of over 30%. Different hormonal treatments have been described following incomplete resection; however no standard therapy currently exists. We review the literature for medical treatments options following incomplete resection of IVL with CE. Methods. Electronic databases were searched for all studies reporting IVL with CE. These studies were then searched for reports of patients with inoperable or incomplete resection and any further medical treatments. Our database was searched for patients with medical therapy following incomplete resection of IVL with CE and their results were included. Results. All studies were either case reports or case series. Five literature reviews confirm that surgery is the only treatment to achieve cure. The uses of progesterone, estrogen modulation, gonadotropin-releasing hormone antagonism, and aromatase inhibition have been described following incomplete resection. Currently no studies have reviewed the outcomes of these treatments. Conclusions. Complete surgical resection is the only means of cure for IVL with CE, while multiple hormonal therapies have been used with varying results following incomplete resection. Aromatase inhibitors are the only reported treatment to prevent tumor progression or recurrence in patients with incompletely resected IVL with CE.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2015-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/756141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65137941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Aorto-Uni-Iliac Stent Grafts with and without Crossover Femorofemoral Bypass for Treatment of Abdominal Aortic Aneurysms: A Parallel Observational Comparative Study 经股股交叉搭桥或不经股股交叉搭桥治疗腹主动脉瘤:平行观察比较研究

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-12-03 DOI: 10.1155/2015/962078

M. Elkassaby, M. Alawy, M. Ali, W. Tawfick, S. Sultan

{"title":"Aorto-Uni-Iliac Stent Grafts with and without Crossover Femorofemoral Bypass for Treatment of Abdominal Aortic Aneurysms: A Parallel Observational Comparative Study","authors":"M. Elkassaby, M. Alawy, M. Ali, W. Tawfick, S. Sultan","doi":"10.1155/2015/962078","DOIUrl":"https://doi.org/10.1155/2015/962078","url":null,"abstract":"We investigated the safety and efficacy of primary aorto-uni-iliac (AUI) endovascular aortic repair (EVAR) without fem-fem crossover in patients with abdominal aortic aneurysm (AAA) and concomitant aortoiliac occlusive disease. 537 EVARs were implemented between 2002 and 2015 in University Hospital Galway, a tertiary referral center for aortic surgery and EVAR. We executed a parallel observational comparative study between 34 patients with AUI with femorofemoral crossover (group A) and six patients treated with AUI but without the crossover (group B). Group B patients presented with infrarenal AAAs with associated total occlusion of one iliac axis and high comorbidities. Technical success was 97% (n = 33) in group A and 85% (n = 5) in group B (P = 0.31). Primary and assisted clinical success at 24 months were 88% (n = 30) and 12% (n = 4), respectively, in group A, and 85% (n = 5) and 15% (n = 1), respectively, in group B (P = 0.125). Reintervention rate was 10% (n = 3) in group A and 0% in group B (P = 0.084). No incidence of postoperative critical lower limb ischemia or amputations occurred in the follow-up period. AUI without crossover bypass is a viable option in selected cases.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2015-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/962078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64185101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Endovascular Stent Placement for Hemodialysis Arteriovenous Access Stenosis 血液透析动静脉通道狭窄的血管内支架置入

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-11-16 DOI: 10.1155/2015/971202

B. Neuen, R. Baer, F. Grainer, M. Mantha

{"title":"Endovascular Stent Placement for Hemodialysis Arteriovenous Access Stenosis","authors":"B. Neuen, R. Baer, F. Grainer, M. Mantha","doi":"10.1155/2015/971202","DOIUrl":"https://doi.org/10.1155/2015/971202","url":null,"abstract":"This study aims to report the outcomes of nitinol and polytetrafluoroethylene covered stent placement to treat hemodialysis arteriovenous access stenosis at a single center over a five-year period. Clinical and radiological information was reviewed retrospectively. Poststent primary and secondary patency rates were determined using Kaplan-Meier analysis. Ten clinical variables were subjected to multivariate Cox regression analysis to determine predictors of patency after stent placement. During the study period 60 stents were deployed in 45 patients, with a mean follow-up of 24.5 months. The clinical and anatomical success rate was 98.3% (59/60). Poststent primary patency rates at 6, 12, and 24 months were 64%, 46%, and 35%, respectively. Poststent secondary patency rates at 6, 12, and 24 months were 95%, 89%, and 85%, respectively. Stent placement for upper arm lesions and in access less than 12 months of age was associated with reduced primary patency (adjusted hazards ratio [HR] 5.1, p = 0.0084, and HR 3.5, p = 0.0029, resp.). Resistant or recurrent stenosis can be successfully treated by endovascular stent placement with durable long-term patency, although multiple procedures are often required. Stent placement for upper arm lesions and in arteriovenous access less than 12 months of age was associated with increased risk of patency loss.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2015-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/971202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64189261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Favorable Outcomes after Implantation of Biodegradable Polymer Coated Sirolimus-Eluting Stents in Diabetic Population: Results from INDOLIMUS-G Diabetic Registry. 在糖尿病患者中植入可生物降解聚合物涂层西罗莫司洗脱支架后的良好结果:来自INDOLIMUS-G糖尿病登记的结果。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-01-01 Epub Date: 2015-09-02 DOI: 10.1155/2015/265670

Anurag Polavarapu, Raghava Sarma Polavarapu, Jayesh Prajapati, Asif Raheem, Kamlesh Thakkar, Shivani Kothari, Ashok Thakkar

{"title":"Favorable Outcomes after Implantation of Biodegradable Polymer Coated Sirolimus-Eluting Stents in Diabetic Population: Results from INDOLIMUS-G Diabetic Registry.","authors":"Anurag Polavarapu, Raghava Sarma Polavarapu, Jayesh Prajapati, Asif Raheem, Kamlesh Thakkar, Shivani Kothari, Ashok Thakkar","doi":"10.1155/2015/265670","DOIUrl":"https://doi.org/10.1155/2015/265670","url":null,"abstract":"Objective. The main aim is to evaluate safety, efficacy, and clinical performance of the Indolimus (Sahajanand Medical Technologies Pvt. Ltd., Surat, India) sirolimus-eluting stent in high-risk diabetic population with complex lesions. Methods. It was a multicentre, retrospective, non-randomized, single-arm study, which enrolled 372 diabetic patients treated with Indolimus. The primary endpoint of the study was major adverse cardiac events (MACE), which is a composite of cardiac death, target lesion revascularization (TLR), target vessel revascularization (TVR), myocardial infarction (MI), and stent thrombosis (ST). The clinical follow-ups were scheduled at 30 days, 6 months, and 9 months. Results. The mean age of the enrolled patients was 53.4 ± 10.2 years. A total of 437 lesions were intervened successfully with 483 stents (1.1 ± 0.3 per lesion). There were 256 (68.8%) male patients. Hypertension and totally occluded lesions were found in 202 (54.3%) and 45 (10.3%) patients, respectively. The incidence of MACE at 30 days, 6 months and 9 months was 0 (0%), 6 (1.6%), and 8 (2.2%), respectively. The event-free survival at 9-month follow-up by Kaplan Meier method was found to be 97.8%. Conclusion. The use of biodegradable polymer coated sirolimus-eluting stent is associated with favorable outcomes. The results demonstrated in our study depict its safety and efficacy in diabetic population. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 ","pages":"265670"},"PeriodicalIF":1.3,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/265670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34048552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A comparison of the efficacy and cost of different venous leg ulcer dressings: a retrospective cohort study. 不同静脉腿部溃疡敷料的疗效和成本比较：一项回顾性队列研究。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-01-01 Epub Date: 2015-04-14 DOI: 10.1155/2015/187531

Syed M Asim Hussain

{"title":"A comparison of the efficacy and cost of different venous leg ulcer dressings: a retrospective cohort study.","authors":"Syed M Asim Hussain","doi":"10.1155/2015/187531","DOIUrl":"10.1155/2015/187531","url":null,"abstract":"Objective. To compare the efficacy and cost-effectiveness of simple nonadherent dressings with other more expensive dressing types in the treatment of venous leg ulcers. Study Design. Retrospective cohort study. Location. The leg ulcer clinic at the University Hospital of South Manchester. Subjects and Methods. The healing rates of twelve leg ulcer patients treated with simple nonadherent dressings (e.g., NA Ultra) were compared with an equal number of patients treated with modern dressings to determine differences in healing rates and cost. Main Outcome Measures. Rate of healing as determined by reduction in ulcer area over a specified period of time and total cost of dressing per patient. Results. Simple nonadherent dressings had a mean healing rate of 0.353 cm(2)/week (standard deviation ± 0.319) compared with a mean of 0.415 cm(2)/week (standard deviation ± 0.383) for more expensive dressings. This resulted in a one-tailed p value of 0.251 and a two-tailed p value of 0.508. Multiple regression analysis gave a significance F of 0.8134. Conclusion. The results indicate that the difference in healing rate between simple and modern dressings is not statistically significant. Therefore, the cost of dressing type should be an important factor influencing dressing selection. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 ","pages":"187531"},"PeriodicalIF":1.3,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33287296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Early and Late Endothelial Progenitor Cells in Peripheral Circulation and Their Clinical Association with Coronary Artery Disease. 外周血早期和晚期内皮祖细胞的测定及其与冠状动脉疾病的临床关系

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-01-01 Epub Date: 2015-09-16 DOI: 10.1155/2015/674213

Shotoku Tagawa, Chiaki Nakanishi, Masayuki Mori, Tsuyoshi Yoshimuta, Shohei Yoshida, Masaya Shimojima, Junichiro Yokawa, Masa-Aki Kawashiri, Masakazu Yamagishi, Kenshi Hayashi

{"title":"Determination of Early and Late Endothelial Progenitor Cells in Peripheral Circulation and Their Clinical Association with Coronary Artery Disease.","authors":"Shotoku Tagawa, Chiaki Nakanishi, Masayuki Mori, Tsuyoshi Yoshimuta, Shohei Yoshida, Masaya Shimojima, Junichiro Yokawa, Masa-Aki Kawashiri, Masakazu Yamagishi, Kenshi Hayashi","doi":"10.1155/2015/674213","DOIUrl":"https://doi.org/10.1155/2015/674213","url":null,"abstract":"The clinical implications of early and late endothelial progenitor cells (EPCs) in coronary artery disease (CAD) remain unclear. We investigated endothelial dysfunction in CAD by simultaneously examining early and late EPC colony formation and gene expression of specific surface markers in EPCs. EPCs were extracted from a total of 83 subjects with (n = 47) and without (n = 36) CAD. Early and late EPC colonies were formed from mononuclear cells extracted from peripheral blood. We found that fewer early EPC colonies were produced in the CAD group (7.2 ± 3.l/well) than those in the control group (12.4 ± 1.4/well, p < 0.05), and more late EPC colonies were produced in the CAD group (0.8 ± 0.2/well) than those in the control group (0.25 ± 0.02/well, p < 0.05). In the CAD group, the relative expression of CD31 and KDR of early and late EPCs was lower than in the control group. These results demonstrate that CAD patients could have increased late EPC density and that early and late EPCs in CAD patients exhibited immature endothelial characteristics. We suggest that changes in EPC colony count and gene expression of endothelial markers may have relation with development of CAD. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 ","pages":"674213"},"PeriodicalIF":1.3,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/674213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34140873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

Contralateral occlusion increases the risk of neurological complications associated with carotid endarterectomy. 对侧闭塞会增加颈动脉内膜切除术引起神经系统并发症的风险。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-01-01 Epub Date: 2015-01-29 DOI: 10.1155/2015/942146

Laura Capoccia, Enrico Sbarigia, Anna Rita Rizzo, Chiara Pranteda, Danilo Menna, Pasqualino Sirignano, Wassim Mansour, Andrea Esposito, Francesco Speziale

{"title":"Contralateral occlusion increases the risk of neurological complications associated with carotid endarterectomy.","authors":"Laura Capoccia, Enrico Sbarigia, Anna Rita Rizzo, Chiara Pranteda, Danilo Menna, Pasqualino Sirignano, Wassim Mansour, Andrea Esposito, Francesco Speziale","doi":"10.1155/2015/942146","DOIUrl":"10.1155/2015/942146","url":null,"abstract":"Objective. To report on the incidence and factors associated with the development of perioperative neurological complications following CEA in patients affected by carotid stenosis with contralateral occlusion (CO) and to compare results between those patients and the whole group of patients submitted to CEA at our vascular division from 1997 to 2012. Methods. Our nonrandomized prospective experience including 1639 patients consecutively submitted to CEA was retrospectively reviewed. 136 patients presented a CO contralateral to the treated carotid stenosis. Outcomes considered for analysis were perioperative neurological death rates, major and minor stroke rates, and a combined endpoint of all neurological complications. Results. CO patients more frequently were male, smokers, younger, and symptomatic (P < 0.001), presented with a preoperative brain infarct and associated peripheral arterial disease (P < 0.0001), and presented with higher perioperative major stroke rate than patients without CO (4.4% versus 1.2%, resp., P = 0.009). Factors associated with the highest neurological risk in CO patients were age >74 years and preoperative brain infarct (P = 0.03). The combination of the abovementioned factors significantly increased complication rates in CO patients submitted to CEA. Conclusions. In our experience CO patients were at high risk for postoperative neurological complications particularly when presenting association of advanced age and preoperative brain infarction. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 ","pages":"942146"},"PeriodicalIF":1.3,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33074943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular leakage in dengue hemorrhagic Fever is associated with dengue infected monocytes, monocyte activation/exhaustion, and cytokines production. 登革出血热的血管渗漏与登革感染单核细胞、单核细胞激活/衰竭和细胞因子产生有关。

IF 1.3

International Journal of Vascular Medicine Pub Date : 2015-01-01 Epub Date: 2015-02-05 DOI: 10.1155/2015/917143

Sirichan Chunhakan, Punnee Butthep, Sutee Yoksan, Kanchana Tangnararatchakit, Ampaiwan Chuansumrit

{"title":"Vascular leakage in dengue hemorrhagic Fever is associated with dengue infected monocytes, monocyte activation/exhaustion, and cytokines production.","authors":"Sirichan Chunhakan, Punnee Butthep, Sutee Yoksan, Kanchana Tangnararatchakit, Ampaiwan Chuansumrit","doi":"10.1155/2015/917143","DOIUrl":"https://doi.org/10.1155/2015/917143","url":null,"abstract":"The vascular leakage was shown by the increment of hematocrit (Hct), dengue viral infected monocyte, monocyte status, and cytokines production in patients infected with dengue virus. Dengue viral antigens were demonstrated in monocytes (CD14+) from peripheral blood mononuclear cells. The increased levels of Hct, interleukin- (IL-) 10, and tumor necrosis factor-alpha (TNF-α) were detected in dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) patients as compared with other febrile illnesses (OFIs). The highest levels of Hct and IL-10 were detected in DSS patients as compared with other groups (P < 0.05) especially on one day before and after defervescence. The unstimulated and lipopolysaccharide- (LPS-) stimulated monocytes from DSS patients showed the significantly decreased of intracellular IL-1β and TNF-α. In addition, the lowest level of mean fluorescence intensity (MFI) of CD11b expression on monocytes surface in DSS patients was also demonstrated. Furthermore, the negative correlations between IL-10 levels and intracellular IL-1β and MFI of CD11b expression in unstimulated and LPS-stimulated monocytes were also detected. Nevertheless, not only were the relationships between the prominent IL-10 and the suppression of intracellular monocyte secretion, namely, IL-1β, TNF-α, demonstrated but also the effect of vascular leakage was observed. ","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2015 ","pages":"917143"},"PeriodicalIF":1.3,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/917143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33088697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31