2型糖尿病患者代谢综合征与外周动脉疾病相关性的年龄和性别差异

IF 2.5 Q2 PERIPHERAL VASCULAR DISEASE
International Journal of Vascular Medicine Pub Date : 2025-03-10 eCollection Date: 2025-01-01 DOI:10.1155/ijvm/5572344
Xiaotong Feng, Yongsong Xu, Lin Zhu, Kun Li, Lin Mao, Huan Dong, Dong Zhao, Jing Ke
{"title":"2型糖尿病患者代谢综合征与外周动脉疾病相关性的年龄和性别差异","authors":"Xiaotong Feng, Yongsong Xu, Lin Zhu, Kun Li, Lin Mao, Huan Dong, Dong Zhao, Jing Ke","doi":"10.1155/ijvm/5572344","DOIUrl":null,"url":null,"abstract":"<p><p><b>Purpose:</b> Our study is aimed at exploring the association between peripheral artery disease (PAD) and metabolic syndrome (MetS) across different age and gender groups among patients with Type 2 diabetes mellitus (T2DM). <b>Patients and Methods:</b> A total of 3638 patients with T2DM were enrolled in the study, including 281 patients with PAD and 3357 patients without PAD. Demographic data and anthropometric measurements, such as height, weight, and waist circumference, were collected. Laboratory tests and ankle-brachial index (ABI) assessment were also conducted. Multiple logistic regression was used to evaluate the relationship between PAD and the number of MetS components across different age and gender groups. <b>Results:</b> After adjusting for potential confounding factors, our results indicated that the ORs for the presence of PAD increased progressively with the number of MetS components. Stratified analysis showed that this effect was particularly pronounced in younger patients (aged < 40 years) and older patients (aged ≥ 60 years), where the risk of PAD rose with an increasing number of MetS components. Furthermore, the positive association between the number of MetS components and PAD presence was significantly stronger in females. <b>Conclusions:</b> In summary, our findings suggest that the risk of PAD is positively correlated with the number of MetS components in patients with T2DM, especially among younger patients and older patients. Additionally, the positive association between the number of MetS components and the presence of PAD was significantly more evident in female patients.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2025 ","pages":"5572344"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991799/pdf/","citationCount":"0","resultStr":"{\"title\":\"Age and Gender Difference in the Association of Metabolic Syndrome and Peripheral Artery Disease Among Patients With Type 2 Diabetes Mellitus.\",\"authors\":\"Xiaotong Feng, Yongsong Xu, Lin Zhu, Kun Li, Lin Mao, Huan Dong, Dong Zhao, Jing Ke\",\"doi\":\"10.1155/ijvm/5572344\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Purpose:</b> Our study is aimed at exploring the association between peripheral artery disease (PAD) and metabolic syndrome (MetS) across different age and gender groups among patients with Type 2 diabetes mellitus (T2DM). <b>Patients and Methods:</b> A total of 3638 patients with T2DM were enrolled in the study, including 281 patients with PAD and 3357 patients without PAD. Demographic data and anthropometric measurements, such as height, weight, and waist circumference, were collected. Laboratory tests and ankle-brachial index (ABI) assessment were also conducted. Multiple logistic regression was used to evaluate the relationship between PAD and the number of MetS components across different age and gender groups. <b>Results:</b> After adjusting for potential confounding factors, our results indicated that the ORs for the presence of PAD increased progressively with the number of MetS components. Stratified analysis showed that this effect was particularly pronounced in younger patients (aged < 40 years) and older patients (aged ≥ 60 years), where the risk of PAD rose with an increasing number of MetS components. Furthermore, the positive association between the number of MetS components and PAD presence was significantly stronger in females. <b>Conclusions:</b> In summary, our findings suggest that the risk of PAD is positively correlated with the number of MetS components in patients with T2DM, especially among younger patients and older patients. Additionally, the positive association between the number of MetS components and the presence of PAD was significantly more evident in female patients.</p>\",\"PeriodicalId\":14448,\"journal\":{\"name\":\"International Journal of Vascular Medicine\",\"volume\":\"2025 \",\"pages\":\"5572344\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991799/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Vascular Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/ijvm/5572344\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Vascular Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/ijvm/5572344","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0

摘要

目的:本研究旨在探讨不同年龄和性别的2型糖尿病(T2DM)患者外周动脉疾病(PAD)与代谢综合征(MetS)之间的关系。患者和方法:共有3638例T2DM患者入组,其中PAD患者281例,非PAD患者3357例。收集了人口统计数据和人体测量数据,如身高、体重和腰围。还进行了实验室检查和踝臂指数(ABI)评估。采用多元逻辑回归评估不同年龄和性别人群中PAD与MetS成分数量之间的关系。结果:在调整了潜在的混杂因素后,我们的结果表明,随着MetS组件的数量增加,PAD存在的or逐渐增加。结论:总之,我们的研究结果表明,PAD的风险与T2DM患者中MetS成分的数量呈正相关,尤其是在年轻患者和老年患者中。此外,MetS成分数量与PAD存在之间的正相关在女性患者中更为明显。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Age and Gender Difference in the Association of Metabolic Syndrome and Peripheral Artery Disease Among Patients With Type 2 Diabetes Mellitus.

Purpose: Our study is aimed at exploring the association between peripheral artery disease (PAD) and metabolic syndrome (MetS) across different age and gender groups among patients with Type 2 diabetes mellitus (T2DM). Patients and Methods: A total of 3638 patients with T2DM were enrolled in the study, including 281 patients with PAD and 3357 patients without PAD. Demographic data and anthropometric measurements, such as height, weight, and waist circumference, were collected. Laboratory tests and ankle-brachial index (ABI) assessment were also conducted. Multiple logistic regression was used to evaluate the relationship between PAD and the number of MetS components across different age and gender groups. Results: After adjusting for potential confounding factors, our results indicated that the ORs for the presence of PAD increased progressively with the number of MetS components. Stratified analysis showed that this effect was particularly pronounced in younger patients (aged < 40 years) and older patients (aged ≥ 60 years), where the risk of PAD rose with an increasing number of MetS components. Furthermore, the positive association between the number of MetS components and PAD presence was significantly stronger in females. Conclusions: In summary, our findings suggest that the risk of PAD is positively correlated with the number of MetS components in patients with T2DM, especially among younger patients and older patients. Additionally, the positive association between the number of MetS components and the presence of PAD was significantly more evident in female patients.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
International Journal of Vascular Medicine
International Journal of Vascular Medicine PERIPHERAL VASCULAR DISEASE-
CiteScore
3.50
自引率
0.00%
发文量
7
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信