International journal of sports medicine最新文献_第7页

Postexercise Physical Recovery Methods for Combat Sports: A Scoping Review. 格斗运动的运动后体能恢复方法：范围综述。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-08-01 DOI: 10.1055/a-2615-3553

Robert Trybulski, Adrian Kużdżał, Adam Kawczyński, Sebastian Klich, Jarosław Muracki, Filipe Manuel Clemente

{"title":"Postexercise Physical Recovery Methods for Combat Sports: A Scoping Review.","authors":"Robert Trybulski, Adrian Kużdżał, Adam Kawczyński, Sebastian Klich, Jarosław Muracki, Filipe Manuel Clemente","doi":"10.1055/a-2615-3553","DOIUrl":"10.1055/a-2615-3553","url":null,"abstract":"This scoping review (1) summarizes postexercise recovery methods for combat sports (CS) athletes and (2) synthesizes their effects on key biochemical, physiological, and physical outcomes. Trained CS athletes were included. Studies examined active (exercise) and passive (e.g., compression) recovery methods, comparing them to controls or alternatives. Outcomes-biochemical, physiological, or physical-were measured pre- and postintervention in experimental and quasi-experimental designs. Study quality and risk of bias were assessed using a modified version of the Downs and Black assessment scale. Searches were performed in PubMed, Scopus, SPORTDiscus, and Web of Science. This review of 27 articles (554 athletes) found mixed effects of recovery methods on biochemistry. Active recovery aids acute lactate reduction, while compression and dry needling enhance pain threshold, perfusion, and muscle tone at 24-48 hours. Most methods have little impact on immediate performance, with few surpassing passive recovery at 24 hours. Different methods are studied in CS, though benefits for biochemical and physical outcomes appear limited. Active recovery aids lactate clearance, while compression and dry needling offer physiological benefits at 24-48 hours. Coaches may use these methods to improve metabolic and muscle recovery posttraining; however, these approaches should be designed to meet the training demands, athlete preferences, and recovery timelines.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Exercise-Induced Muscle Damage on Muscle and Cerebral Oxygenation and Performance. 运动诱导的肌肉损伤对肌肉和大脑氧合及运动性能的影响。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-08-01 DOI: 10.1055/a-2644-4923

Vassilis Bobotas, Panagiotis N Chatzinikolaou, Spyridon Methenitis, Eleni Doika, Polyxeni Spiliopoulou, Vassiliki J Malliou, Thomas Mpampoulis, Gerasimos Terzis, Nikolaos Geladas, Vassilis Paschalis

{"title":"The Effect of Exercise-Induced Muscle Damage on Muscle and Cerebral Oxygenation and Performance.","authors":"Vassilis Bobotas, Panagiotis N Chatzinikolaou, Spyridon Methenitis, Eleni Doika, Polyxeni Spiliopoulou, Vassiliki J Malliou, Thomas Mpampoulis, Gerasimos Terzis, Nikolaos Geladas, Vassilis Paschalis","doi":"10.1055/a-2644-4923","DOIUrl":"10.1055/a-2644-4923","url":null,"abstract":"The study aimed to investigate the effects of exercise-induced muscle damage on muscle and cerebral oxygenation. Twelve healthy men performed eccentric exercise on a leg press machine at an intensity corresponding to their concentric one-repetition maximum. Muscle damage indices, muscle and cerebral oxygenation, and vastus lateralis architecture were evaluated at baseline and 48 hours postexercise. At 48 hours postexercise, delayed onset muscle soreness significantly increased (1.0±0.3 to 4.2±2.8; p<0.01), while concentric one-repetition maximum, maximal isometric force, and rate of force development decreased (p<0.01). The quadriceps' cross-sectional area and muscle thickness significantly increased (p<0.05). During a 5-second maximal isometric contraction, the tissue oxygen saturation index (TSI) of the vastus lateralis (63±3-61±4%; p>0.05) and the prefrontal cortex (68±2-67±1%; p>0.05) did not change significantly. Deoxyhemoglobin showed a marginally significant decrease (1.16±1.14-0.06±1.10 µM; p=0.049). No significant changes were observed in muscle and cerebral oxygenation parameters during the 30-second maximal isometric contraction. The eccentric exercise protocol induced muscle damage and altered muscle architecture. However, these changes were not sufficient to affect muscle or cerebral TSI during either short- or long-duration maximal isometric contraction. Eccentric exercise-induced muscle damage was not found to induce changes in cerebral oxygenation.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood Flow Restriction Accelerates Recruitment During a High-Intensity Non-Volitional Task. 在高强度的非自愿性任务中，血流限制会加速招募。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-31 DOI: 10.1055/a-2644-5025

Lyric Richardson, Alex Olmos, Tony Montgomery, Kylie Burleson, Pasquale Succi, Sean M Lubiak, Taylor K Dinyer-McNeely, Shane M Hammer, Haley C Bergstrom, Ethan C Hill, Michael A Trevino

{"title":"Blood Flow Restriction Accelerates Recruitment During a High-Intensity Non-Volitional Task.","authors":"Lyric Richardson, Alex Olmos, Tony Montgomery, Kylie Burleson, Pasquale Succi, Sean M Lubiak, Taylor K Dinyer-McNeely, Shane M Hammer, Haley C Bergstrom, Ethan C Hill, Michael A Trevino","doi":"10.1055/a-2644-5025","DOIUrl":"10.1055/a-2644-5025","url":null,"abstract":"This study examined blood flow restriction (BFR) usage and motor unit (MU) behavior of the biceps brachii during a single high-intensity contraction. Twelve resistance-trained males (25±5 y) completed maximal voluntary contractions (MVCs) of the elbow flexors, followed by a 70% MVC with BFR and without BFR (CON). Surface electromyographic (EMG) signals from the 70% MVCs were decomposed to extract MU: recruitment thresholds (RTs), action potential amplitudes (MUAPAMPS), and mean firing rates (MFRs). EMG amplitude (EMGRMS) at 70% MVC was normalized (N-EMGRMS) to MVC EMGRMS. Paired samples t-tests compared the y-intercepts and slopes of the MUAPAMP and MFR vs. RT relationships and N-EMGRMS between treatments. For the MUAPAMP vs. RT relationships, the y-intercepts were greater (p=0.016) for CON than BFR, whereas the slopes were greater (p=0.024) for BFR than CON. For the MFR vs. RT relationships, the y-intercepts were greater (p=0.039) for BFR than CON, whereas the slopes were more negative (p=0.023) for BFR than CON. N-EMGRMS was greater (p=0.038) for BFR than CON. BFR accelerated higher-threshold MU recruitment, increased lower-threshold MU firing rates, and increased N-EMGRMS during a single high-intensity muscle action. BFR may be beneficial for accelerating MU recruitment in populations/scenarios where near-maximal efforts are contraindicated.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Long-Term Effects of Combined Training and 1-Year Follow-Up in Breast Cancer Survivors. 联合训练和1年随访对乳腺癌幸存者的长期影响。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-31 DOI: 10.1055/a-2631-9747

Thais R S de Paulo, Fabricio Eduardo Rossi, Priscila Almeira Queiroz Rossi, Lucas Melo Neves, Ismael Forte Freitas

{"title":"The Long-Term Effects of Combined Training and 1-Year Follow-Up in Breast Cancer Survivors.","authors":"Thais R S de Paulo, Fabricio Eduardo Rossi, Priscila Almeira Queiroz Rossi, Lucas Melo Neves, Ismael Forte Freitas","doi":"10.1055/a-2631-9747","DOIUrl":"https://doi.org/10.1055/a-2631-9747","url":null,"abstract":"The use of aromatase inhibitor (AI) therapy in breast cancer survivors (BCS) has been linked to significant and negative changes in body composition and quality of life. However, the long-term effects (9 months) of combined training (CT=resistance plus aerobic training) following the interruption of CT intervention remain unclear in these variables. Thus, the present study aimed to investigate changes in body composition, bone mineral density, and quality of life during a 1-year follow-up period after 9 months of CT in BCS. Participants were randomized into two groups: CT (n=18) for 9 months, or control group (n=18), with 27 participants (CT=16; control=11) reassessed after the 1-year follow-up. There were significant group×time interactions postintervention, with lower fat mass and fat mass percentage in the CT group. However, after the follow-up period, these values returned to baseline. The CT group shows improvements in quality of life, with higher scores in physical functioning, physical health, social functioning, bodily pain, and vitality compared to the control group. These benefits were maintained after the 1-year follow-up period only in the CT group. This study reinforces the crucial role of consistently maintaining an exercise training program for BCS undergoing AI therapy.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aerobic Training and Pulse Wave Velocity in People with Normal and Elevated Blood Pressure. 血压正常和血压升高人群的有氧训练和脉搏波速度。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-31 DOI: 10.1055/a-2647-2170

Ricardo Cordeiro, Jeferson Rocha, José Silva, Sabrina Santos, Bruno Oliveira, Michel Silva, Paulo Farinatti

{"title":"Aerobic Training and Pulse Wave Velocity in People with Normal and Elevated Blood Pressure.","authors":"Ricardo Cordeiro, Jeferson Rocha, José Silva, Sabrina Santos, Bruno Oliveira, Michel Silva, Paulo Farinatti","doi":"10.1055/a-2647-2170","DOIUrl":"10.1055/a-2647-2170","url":null,"abstract":"Research on chronic aerobic exercise (AE) and arterial stiffness has yielded mixed results, largely due to differences in participant characteristics and training protocols. This meta-analysis included 26 trials (40 interventions; n=756; average age 42±15 y) to assess AE's effect on arterial stiffness, measured by pulse wave velocity (PWV) and to explore moderating factors. AE programs averaged 40±19 minutes/session, 3±1 d/wk, over 11±8 weeks, with intensities between 3 and 8 METs. Random-effects analysis showed AE significantly reduced central (- 1.02 m/s), mixed (- 0.34 m/s), and peripheral (- 0.72 m/s) PWV, with an overall mean reduction of-0.93 m/s and no differences between arterial beds. However, only a subset of studies showed significant reductions: 9/25 for central, 3/6 for mixed, and 4/8 for peripheral PWV. Studies with higher methodological quality yielded larger effect sizes. Reductions in PWV were consistent across participants with normal or high blood pressure, differing baseline PWV, and both younger and older adults, regardless of blood pressure changes. The impact of training components was inconsistent, suggesting AE benefits across a range of intensities and volumes. Overall, AE appears to reduce arterial stiffness across diverse populations and exercise protocols, supporting its role in improving vascular health.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying Match Sequence Thresholds to Mitigate Physical Decline During Congested Fixtures. 识别匹配序列阈值，以减轻拥挤期间的物理下降。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-31 DOI: 10.1055/a-2630-7119

Hugo Silva, Pedro Menezes, Ibai Errekagorri, Fábio Yuzo Nakamura, Rui Marcelino

{"title":"Identifying Match Sequence Thresholds to Mitigate Physical Decline During Congested Fixtures.","authors":"Hugo Silva, Pedro Menezes, Ibai Errekagorri, Fábio Yuzo Nakamura, Rui Marcelino","doi":"10.1055/a-2630-7119","DOIUrl":"10.1055/a-2630-7119","url":null,"abstract":"This study compares locomotor activities during matches with different recovery intervals (<72, 72-120, 121-168,>168 h), considering accumulated travel distances (0, 1-250, 251-1,000,>1,000 km) in the previous 3, 5, and 7 days, and match sequence during congested periods. Locomotor data were collected using a global navigation satellite system and included total distance, distance covered between 14-20, 20-25, 25-30, and>30 km/h, maximal speed, maximal accelerations and decelerations, and the number of accelerations and decelerations between 2 and 3 m/s2. Congested fixtures (<72 and 72-120 h) negatively affected locomotor activities compared to noncongested ones (>168 h), with players covering less total distance (p=0.026) and distance at 14-20 km/h (p=0.027) and performing fewer accelerations (p=0.001) and decelerations (p=0.022) between 2 and 3 m/s2. Additionally, interactions with accumulated kilometers traveled revealed that high accumulated distances in the days leading up to congested fixtures exacerbated reductions in locomotor performance (p<0.05). Analysis of specific cases of consecutive congested fixtures showed a decline in locomotor activities after three matches within<72 hours or four matches within<120 hours. These findings highlight the importance of managing fixture schedules and travel distances to optimize player performance and reduce the risk of injury during congested match periods, with limiting players to short match sequences potentially being beneficial.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Description of Scapular Biomechanics in the Windmill Softball Pitch in Early High School Pitchers. 高中早期投手风车垒球球场的肩胛骨生物力学描述。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-30 DOI: 10.1055/a-2647-0188

Kaila A Holtz, Benjamin Lerch, Jason L Zaremski, Lauren Butler, Sophia Ulman, Ryan Zappa, Anthony Fava, Gretchen D Oliver

{"title":"A Description of Scapular Biomechanics in the Windmill Softball Pitch in Early High School Pitchers.","authors":"Kaila A Holtz, Benjamin Lerch, Jason L Zaremski, Lauren Butler, Sophia Ulman, Ryan Zappa, Anthony Fava, Gretchen D Oliver","doi":"10.1055/a-2647-0188","DOIUrl":"https://doi.org/10.1055/a-2647-0188","url":null,"abstract":"The scapula facilitates the windmill pitching motion, providing a stable base for the shoulder muscles to accelerate the humerus. Given the repetitive range of motion facilitated by the shoulder musculature about the scapula, shoulder overuse injuries are a significant concern in softball pitchers. Therefore, we aimed to provide normative values of scapular kinematics during the windmill pitching motion in high school-aged softball pitchers. Kinematic data from 17 high school-aged softball pitchers (15±1 y; 1.7±0.1 m; 72.3±15.0 kg) throwing fastball pitches at regulation distance 13.1 m (43 ft) were obtained using an electromagnetic tracking system synced with motion analysis. Scapular kinematics throughout the windmill pitching motion indicated that the scapula maintains an anteriorly tilted and internally rotated (protracted) position while moving within 5 and 22° in each plane, respectively. Additionally, on average, the scapula remained upwardly rotated throughout the start and top of the pitch, through foot contact, but moved into downward rotation at ball release. Description of scapular biomechanics during the windmill softball pitch is an area that has not been extensively researched. Our data reinforce the significance of the scapula as a dynamic stabilizer of the shoulder and its critical role in the kinematics and kinetics of the fastpitch softball windmill pitch.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anaerobic Alactic Energy Assessment in Short-Distance Maximal Swimming Performance. 短距离极限游泳运动中的无氧无水能量评价。

IF 2.2 4区医学

International journal of sports medicine Pub Date : 2025-07-28 DOI: 10.1055/a-2630-4269

Jesús J Ruiz-Navarro, Ana Gay, Raúl Arellano, Rodrigo Zacca

{"title":"Anaerobic Alactic Energy Assessment in Short-Distance Maximal Swimming Performance.","authors":"Jesús J Ruiz-Navarro, Ana Gay, Raúl Arellano, Rodrigo Zacca","doi":"10.1055/a-2630-4269","DOIUrl":"10.1055/a-2630-4269","url":null,"abstract":"We aimed to compare the anaerobic alactic (AnAL) energy expenditure from a 50-m front crawl swimming between two methodologies in highly trained short-distance swimmers: (i) based on the maximal phosphocreatine (PCr) splitting in contracting muscles (AnALPCRSPLITTING) and (ii) based on the oxygen uptake ( ˙VO2) off-kinetics, where AnAL is estimated from the area under the curve of the fast component (amplitude in liters×time constant in minutes) of the 10-minute of excess postexercise oxygen consumption (AnALVO2KINETICS). Thirty-nine 50-m front-crawl all-out (time trial) swimming performances and respective off-transient kinetics pulmonary ˙VO2 samples (23 men: 17.0±2.6 y and; 16 women: 17.0±2.1 y) were analyzed. We observed no differences (η 2 p=0.044; p=0.068) between AnALPCRSPLITTING (41.7±6.1 kJ) and AnALVO2KINETICS (37.6±12.7 kJ). Bland-Altman plots indicated high bias (3.79-4.42 kJ) and precision (agreement) (limits:-21.31 to 30.14 kJ) between methods, with repeatability ranging from \"poor\" to \"moderate\" (intraclass correlation coefficients: 0.34-0.53; p=0.018-0.157), indicating proportional error that varies with the magnitude of the measurements. Although both methods showed overall agreement, their conceptual and methodological differences introduce proportional error. Thus, they should not be used interchangeably, but rather considered complementary, when feasible, to provide a more comprehensive understanding of AnAL energy expenditure in short-duration maximal efforts such as 50-m swimming.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteoarthritis Exercise Interventions for a Younger Adult Population-A Narrative Review. 骨关节炎运动干预对年轻成人人群的影响。

IF 2 4区医学

International journal of sports medicine Pub Date : 2025-07-23 DOI: 10.1055/a-2627-3277

Fearghal P Behan, Thomas Oswald, Oliver O'Sullivan

{"title":"Osteoarthritis Exercise Interventions for a Younger Adult Population-A Narrative Review.","authors":"Fearghal P Behan, Thomas Oswald, Oliver O'Sullivan","doi":"10.1055/a-2627-3277","DOIUrl":"https://doi.org/10.1055/a-2627-3277","url":null,"abstract":"Osteoarthritis (OA) is considered to be a condition attributable to ageing; however, symptoms can start under 45 years old in one-fifth of patients. Exercise therapy is recommended as first-line treatment in all OA guidance; however, uncertainty remains regarding optimal exercise programmes (including strength, aerobic or mind-body interventions) as different populations might respond better to one intervention than another. This review aims to understand the evidence surrounding exercise interventions for OA in younger adults (18-50 years old). An umbrella review methodology was adopted. Individual studies included in 50 systematic reviews (±meta-analyses) published in the last decade were reviewed and those involving participants aged 18-50 were selected. Five papers, from a potential 1046, involved appropriate participants and underwent full-text review. Two were excluded due to pathology and language; therefore, three studies with 265 participants were included. Exercise interventions included strength-based, neuromuscular control and aerobic and were delivered under supervision or via sensor or virtual reality technology. Interventions improved pain, functional, cartilage composition and inflammatory outcomes measures; however, study heterogeneity prevented direct comparison and meta-analysis. There is a clear bias in the literature for an older population, with research and clinical interventions required for a younger adult population with, or at risk of, OA.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transdermal Uptake of Substances Banned in Sports and Its Relevance for Doping Controls. 体育运动中禁用物质的经皮吸收及其与兴奋剂控制的相关性。

IF 2 4区医学

International journal of sports medicine Pub Date : 2025-07-17 DOI: 10.1055/a-2638-6717

Sophia Krombholz, Linus Korsmeier, Mario Thevis

{"title":"Transdermal Uptake of Substances Banned in Sports and Its Relevance for Doping Controls.","authors":"Sophia Krombholz, Linus Korsmeier, Mario Thevis","doi":"10.1055/a-2638-6717","DOIUrl":"https://doi.org/10.1055/a-2638-6717","url":null,"abstract":"Transdermal drug delivery has emerged as an area of significant interest in both pharmaceutical sciences and antidoping research. This narrative review explores the implications of transdermal uptake of substances banned in sports, emphasizing its relevance for doping control analysis. The human skin's complex role as both a barrier and a site of drug absorption is examined, alongside studies investigating the transdermal administration of substances on the World Anti-Doping Agency Prohibited List, including approved transdermal formulations and drug candidates. Recent cases demonstrate that (unintentional) dermal exposure of athletes to substances banned in professional sports, e.g., clostebol, can lead to an adverse analytical finding in doping controls. Consequently, studies investigating the detectability and metabolism of transdermally administered doping substances, which might even support identifying the route of exposure, are becoming increasingly important. This review emphasizes the relevance of addressing the skin as a pathway for both intentional doping and unintentional contamination, outlining critical implications for global antidoping efforts and future research priorities.","PeriodicalId":14439,"journal":{"name":"International journal of sports medicine","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0