International Research Journal Of Pharmacy最新文献_第2页

Coalescence of Au Nanoparticles in Silica Gel under Electron Beam Irradiation 电子束辐照下金纳米颗粒在硅胶中的聚结

International Research Journal Of Pharmacy Pub Date : 2023-04-15 DOI: 10.52711/0974-4150.2023.00019

Heena Sammi, Manish Mohanta, Bhagwati Sharma, Neha Sardana

引用次数: 0

FORMULATION AND EVALUATION OF HYDRODYNAMICALLY BALANCED FLOATING TABLETS OF GLYCYRRHIZA GLABRA EXTRACT 甘草浸膏水动力平衡浮片的配方及评价

International Research Journal Of Pharmacy Pub Date : 2022-03-31 DOI: 10.7897/2230-8407.1302181

R. S, R. M., K. S, M. M., N. S, S. C, M. R

{"title":"FORMULATION AND EVALUATION OF HYDRODYNAMICALLY BALANCED FLOATING TABLETS OF GLYCYRRHIZA GLABRA EXTRACT","authors":"R. S, R. M., K. S, M. M., N. S, S. C, M. R","doi":"10.7897/2230-8407.1302181","DOIUrl":"https://doi.org/10.7897/2230-8407.1302181","url":null,"abstract":"The aim of the study is to formulate, optimize and evaluate Glycyrrhiza glabra floating tablets using 23 optimization technique for the treatment of asthma. The extract of Glycyrrhiza glabra was prepared by subjecting crude drug to hot continuous percolation method using Soxhlet apparatus using distilled water and ethanol. The floating matrix tablets of Glycyrrhiza glabra was prepared by wet granulation technique using extract of Glycyrrhiza glabra, HPMC K15M as polymer, starch/honey as binder and sodium bicarbonate & citric acid as effervescent agents by 23 factorial design. The independent variables are polymer (X1), concentrations of effervescence agents (X2) and binders used for granulation (X3). The dependent variables are hardness (Y1), buoyancy lag time (Y2), total floating time (Y3), and in-vitro drug release (Y4). The compatibility studies showed that there is no chemical interaction between the drug, polymer and the excipients used in the tablets. The prepared floating tablets were subjected to all post compression parameters such as hardness, friability, swelling capacity, buoyancy, total floating time, drug content &in-vitro drug release and were found to be within normal limits. Based on drug content, buoyancy lag time and in-vitro drug release the formulations F8 was found to be the promising system for anti-asthmatic therapy. The present study reports for the development of gastric floating tablet for Glycyrrhiza glabra following oral administration.","PeriodicalId":14413,"journal":{"name":"International Research Journal Of Pharmacy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73549625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF NEWER POLY HERBAL FORMULATIONS FOR WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY 对伤口愈合和抗炎活性的新聚草药配方的评价

International Research Journal Of Pharmacy Pub Date : 2022-03-31 DOI: 10.7897/2230-8407.1302180

Soujanya K, Mohammad Mazin, Teja ., Ifaaf Parveen, R. .

{"title":"EVALUATION OF NEWER POLY HERBAL FORMULATIONS FOR WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY","authors":"Soujanya K, Mohammad Mazin, Teja ., Ifaaf Parveen, R. .","doi":"10.7897/2230-8407.1302180","DOIUrl":"https://doi.org/10.7897/2230-8407.1302180","url":null,"abstract":"According to Herbalism, independent medicinal herbs are not sufficient to obtain the required pharmacological effect, but when we use these herbal compounds in combination at appropriate proportions will help to obtain maximum pharmacological effects with minimal toxic effects. In this present study, efforts were made to develop an intervention with a poly herbal formulation which was prepared from ethanolic leaf extracts of Chromolaena odorata, Tridax procumbens, Euphorbia hirta Linn. The impact of poly herbalism is assessed for its wound healing property by using excision wound model and anti-inflammatory property by using formalin induced paw oedema model. For wound healing assessment two polyherbal formulations F1 and F2 are prepared with 2% and 4% W/W. These formulations were examined for stability studies. F1(*p<0.005) and F2 (**p<0.001) have shown significant wound closure and faster epithelialisation when compared to standard Povidone-Iodine (5%) ointment (**p<0.001). For assessing anti-inflammatory activity, the poly herbal formulations are prepared as 2% (F1) and 4% (F2) solutions. The doses from each formulation are given as 100 mg/kg, 200 mg/kg and 300 mg/kg to different groups of animals. Both the poly herbal formulations have shown significant results F1(*p<0.05, **p<0.005) and F2 (***p<0.0005, ****p<0.0001) respectively when compared to standard Indomethacin 4 mg/kg dose (****p<0.0001). This study has revealed that poly herbal formulations have shown better anti-inflammatory and wound healing properties due to the synergism of the phytochemicals present in these plant extracts which may lead to future developments of potential poly herbal formulations in the treatment of wounds and inflammatory mediated diseases.","PeriodicalId":14413,"journal":{"name":"International Research Journal Of Pharmacy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81016886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A REVIEW ON DERIVATIVE UV SPECTROSCOPY 导数紫外光谱研究进展

International Research Journal Of Pharmacy Pub Date : 2022-03-31 DOI: 10.7897/2230-8407.1302179

R. Sri, G. Sowmya, K. Bhavyasri, M. Sumakanth

引用次数: 1

JATYADI GHRITA IN POST-OPERATIVE PAIN MANAGEMENT: A REVIEW Jatyadi ghrita在术后疼痛管理中的应用综述

International Research Journal Of Pharmacy Pub Date : 2022-01-31 DOI: 10.7897/2230-8407.1301177

Srinivasa N V, Anand Katti

引用次数: 0

A REVIEW ON IMPORTANCE OF PATHYA-APATHYA IN PANCHAKARMA 病理-病理在panchakarma中的重要性综述

International Research Journal Of Pharmacy Pub Date : 2022-01-31 DOI: 10.7897/2230-8407.1301178

H. Vasudev, Anagha B. R., M. H. S, Ganesh Puttur

引用次数: 0

REVIEW ON THE RESTORATIVE IMPACT OF ACACIA ARABICA 阿拉伯合欢的恢复性作用研究进展

International Research Journal Of Pharmacy Pub Date : 2022-01-15 DOI: 10.7897/2230-8407.1212173

Bibhas Pandit, Ritika K. Singh, Honey Jajo, T. Satapathy

{"title":"REVIEW ON THE RESTORATIVE IMPACT OF ACACIA ARABICA","authors":"Bibhas Pandit, Ritika K. Singh, Honey Jajo, T. Satapathy","doi":"10.7897/2230-8407.1212173","DOIUrl":"https://doi.org/10.7897/2230-8407.1212173","url":null,"abstract":"From ancients, herbal medicines are used in the management and cure of various physiological abnormalities. In this 21st century, a huge part of the world's population still depends mostly on the conventional system of medicine as these medicines are economical, easily available, and have minimal side effects. Acacia arabica commonly known as Babool, indigenously found in India possessed a variety of pharmacological effects when used in different traditional formulations. There are about 1350 Acacia species available worldwide. In India, Acacia arabica is widely spread in Jammu, Himachal Pradesh, Uttar Pradesh, Punjab, Madhya Pradesh, Orissa Bihar, and Andhra Pradesh. The use of Acacia arabica in the traditional formulation is popularized due to its diverse pharmacological activity. Recent research on Acacia arabica revealed that the plant is rich in antioxidants such as catechin, ellagic acid, epigallocatechin, kaempferol, gallic acid and is used in the treatment of inflammation, pain, diabetes, allergy, asthma, bronchitis, amoebiasis, dermatitis, and cardiovascular diseases like hypertension, atherosclerosis, and myocardial infarction. Acacia arabica is also found to be efficient in infection caused by bacterial, fungus, and protozoa. In this present review, our sincere efforts have been given to summarize the various biological active ingredients of Acacia arabica and their pharmacological effects reported by different researchers.","PeriodicalId":14413,"journal":{"name":"International Research Journal Of Pharmacy","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75396182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A RANDOMISED OPEN LABELLED COMPARATIVE PARALLEL GROUP CLINICAL STUDY TO EVALUATE THE EFFICACY OF INTERFERENTIAL THERAPY & KATI BASTI IN GRIDHRASI WITH SPECIAL REFERENCE TO SCIATICA 一项随机、开放标记、比较平行组临床研究，评价干预治疗坐骨神经痛的疗效

International Research Journal Of Pharmacy Pub Date : 2022-01-15 DOI: 10.7897/2230-8407.1212176

Biraj Jung Khadka, Ganesh Puttur

{"title":"A RANDOMISED OPEN LABELLED COMPARATIVE PARALLEL GROUP CLINICAL STUDY TO EVALUATE THE EFFICACY OF INTERFERENTIAL THERAPY & KATI BASTI IN GRIDHRASI WITH SPECIAL REFERENCE TO SCIATICA","authors":"Biraj Jung Khadka, Ganesh Puttur","doi":"10.7897/2230-8407.1212176","DOIUrl":"https://doi.org/10.7897/2230-8407.1212176","url":null,"abstract":"Snigdha Swedana plays an important role in the management of Vata Vyadhi among which Katibasti is one which is indicated in Vata related pathogenesis in Kati Pradesha. Gridhrasi is a Vataja Nanatmaja Vyadhi. Katibasti is an effective treatment in Gridhrasi as it acts as both Snehana and Swedana. Interferential therapy is a form of electrical current that is primarily used for relief from pain. It is said to be effective in case of low back pain. Both Katibasti and Interferential therapy are commonly used treatment modalities in sciatica, hence the present study is intended to compare the efficacy of Katibasti and Interferential therapy in the treatment of Gridhrasi. Thirty-four subjects of Gridhrasi were randomly distributed in 2 groups (A and B) of 15 subjects each. Group A subjects were treated with Katibasti using Maha Vishagarbha Taila for 7 days. Group B subjects were treated with Interferential Therapy for 7 days. Follow up was done on the 14th day. The statistical analysis within the group showed significant improvement in all the parameters in Katibasti group as well as IFT group. Comparative analysis between the groups showed no significant difference between the groups in all the parameters. Clinically, there was a slight difference between two groups. During follow up it was noticed that symptomatic relief was more in Katibasti than Interferential Therapy.","PeriodicalId":14413,"journal":{"name":"International Research Journal Of Pharmacy","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78950760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FORMULATION AND EVALUATION OF POLYHERBAL SHAMPOO CONTAINING EXTRACT OF HIBISCUS, HOLY BASIL AND FENUGREEK 含有芙蓉、圣罗勒和胡芦巴提取物的多草药洗发水的配方和评价

International Research Journal Of Pharmacy Pub Date : 2022-01-15 DOI: 10.7897/2230-8407.1212175

V. Bhat, R. Kumar, A. ., Farnaaz Baji Siraj, Lamiya Raja, Sandeep Jain

{"title":"FORMULATION AND EVALUATION OF POLYHERBAL SHAMPOO CONTAINING EXTRACT OF HIBISCUS, HOLY BASIL AND FENUGREEK","authors":"V. Bhat, R. Kumar, A. ., Farnaaz Baji Siraj, Lamiya Raja, Sandeep Jain","doi":"10.7897/2230-8407.1212175","DOIUrl":"https://doi.org/10.7897/2230-8407.1212175","url":null,"abstract":"Shampoos has primarily been products that are intended to cleanse the hair and scalp. Herbal preparations always functional and have good activity and very minimal or no adverse effects on performance with synthetic. This study intended to prepare/ formulate and evaluate a complete herbal shampoo containing plant materials used only traditionally. The herbal shampoo prepared containing aqueous extracts of petals of Hibiscus (Hibiscus rosa-sinensis), leaves of Holy basil (Ocimum tenuiflorum) and dried leaves of Fenugreek (Trigonella foenum graecum) prepared by decoction method individually. Various physicochemical parameters such as color, clarity, pH and skin irritability, viscosity, surface tension, foaming ability and stability, and stability studies were studied using suitable procedures. The organoleptic evaluations of the polyherbal shampoo showed good results. The pH of the polyherbal shampoo range to be 5, which was near to skin pH. The viscosity of prepared polyherbal shampoo was found to be 0.0696 poise. The surface tension of prepared polyherbal shampoo was found to be 34.1 dynes/cm respectively.","PeriodicalId":14413,"journal":{"name":"International Research Journal Of Pharmacy","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86130388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VALIDATION OF SCREENING MODEL OF CANCER: A REVIEW 癌症筛查模型的验证:综述

International Research Journal Of Pharmacy Pub Date : 2022-01-15 DOI: 10.7897/2230-8407.1212172

Ankita Tripathi, U. ., K. Bhardwaj, Meenakshi V. Gupta, Shristi Raj, Farheen Shareef

引用次数: 0