International Journal of Tuberculosis and Lung Disease最新文献_第2页

Expanding TB infection screening and treatment to eliminate TB. 扩大结核病感染筛查和治疗以消除结核病。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.25.0048

N Riccardi, T Matucci, G Sotgiu

引用次数: 0

Adaptation and validation of perceived HIV and TB stigma scales among persons with TB. 适应和验证结核病患者感知的艾滋病毒和结核病污名量表。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0497

M N Ponticiello, L M Nanziri, R Hennein, E Ochom, A J Gupta, P Turimumahoro, M A White, M Armstrong-Hough, A Katamba, J L Davis

{"title":"Adaptation and validation of perceived HIV and TB stigma scales among persons with TB.","authors":"M N Ponticiello, L M Nanziri, R Hennein, E Ochom, A J Gupta, P Turimumahoro, M A White, M Armstrong-Hough, A Katamba, J L Davis","doi":"10.5588/ijtld.24.0497","DOIUrl":"10.5588/ijtld.24.0497","url":null,"abstract":"<sec><title>BACKGROUND</title>Stigma is a barrier to care for people affected by TB and HIV in Uganda, where these conditions remain endemic. While scales have been adapted and validated to measure stigma among TB-affected households in Uganda, there is a need for scales that measure the experiences of persons with TB (PWTB).</sec><sec><title>METHODS</title>We adapted the Van Rie 12-item individual perspectives TB scale and 10-item individual perspectives HIV scale for use in Uganda through cross-cultural discussions with a multidisciplinary research team and four cognitive interviews with community health workers and PWTB. We then conducted a cross-sectional study administering each scale to 125 PWTB. We performed exploratory factor analysis, evaluated internal validity, and assessed convergent validity with perceived social support.</sec><sec><title>RESULTS</title>Exploratory factor analysis yielded a one-factor solution for both scales, with marginal model fit (standardised root mean square residual = 0.09 for TB, = 0.07 for HIV). There was evidence of convergent validity through a positive correlation of the TB (r = 0.22, p = 0.01) and HIV stigma (r = 0.22, p = 0.01) scales with perceived social support. Both scales had good internal validity (Cronbach's α = 0.86 for TB, = 0.87 for HIV).</sec><sec><title>CONCLUSION</title>Adapted scales to measure perceived HIV and TB stigma among PWTB in Uganda demonstrated promising psychometric properties by removing one and two items, respectively.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"29 3","pages":"127-134"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urine metabolite-determined isoniazid adherence under programmatic conditions in people living with HIV. 艾滋病毒感染者在规划条件下尿代谢物测定异烟肼依从性。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0406

S A Nabity, A D Moffitt, K Mponda, M Melgar, S B Zimba, D Surie, R E Marshall, R Nyirenda, B Girma, T F Mekonnen, A Maida, A F Auld, L J Gunde, A S Muula, S Gutreuter, J E Oeltmann

{"title":"Urine metabolite-determined isoniazid adherence under programmatic conditions in people living with HIV.","authors":"S A Nabity, A D Moffitt, K Mponda, M Melgar, S B Zimba, D Surie, R E Marshall, R Nyirenda, B Girma, T F Mekonnen, A Maida, A F Auld, L J Gunde, A S Muula, S Gutreuter, J E Oeltmann","doi":"10.5588/ijtld.24.0406","DOIUrl":"10.5588/ijtld.24.0406","url":null,"abstract":"<sec><title>BACKGROUND</title>Chemotherapy to prevent TB is a core component of care for persons living with HIV (PLHIV). There are few reports describing adherence to TB prevention under programmatic conditions in high TB burden settings.</sec><sec><title>METHODS</title>We measured adherence to daily isoniazid (INH) preventive treatment (IPT) using a commercially available colourimetric assay to detect urine INH metabolites among PLHIV who self-reported INH ingestion within the preceding 24 h. Enrollee characteristics associated with non-adherence despite self-reported INH ingestion were identified in multivariate log-binomial regression. Interoperator reliability for the detection of INH metabolites was calculated among three independent operators.</sec><sec><title>RESULTS</title>Self-reported INH ingestion and metabolite data were known for 300 PLHIV. INH metabolite was detected in 112 (68.7%) of 163 PLHIV who self-reported INH ingestion in the preceding 24 h. The prevalence of alcohol consumption was significantly higher among INH-non-adherent PLHIV compared with INH-adherent PLHIV (adjusted prevalence ratio 2.43, 95% CI 1.16-5.12). Two-way interoperator reliability ranged from κ 0.86 to κ 0.94.</sec><sec><title>CONCLUSIONS</title>Compared with self-reported 24-h INH ingestion in a high TB-HIV-incidence programmatic setting, biometric adherence to IPT was suboptimal in this sample of PLHIV. Alcohol consumption was the only potentially modifiable risk factor significantly associated with INH non-adherence. Colourimetric interpretation reliability across three operators was moderate/strong.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"29 3","pages":"97-102"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stagnation in the decline of TB in Japan: introduction of the pre-entry TB screening programme. 日本结核病下降停滞不前：引入入境前结核病筛查规划。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0507

T Ukai, S Lee, K S Thu, K Sugiura, A Ohkado

引用次数: 0

Epidemiology, detection, diagnosis and treatment of TB in children in Kazakhstan. 哈萨克斯坦儿童结核病的流行病学、检测、诊断和治疗。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0536

O Prikhodchenko, Y Arbuzova, K Serikbayeva, G Zhakhina, A Rakisheva, G Mussabekova, R Akhmedullin, A Tursynbayeva, A Gaipov, M Adenov, S Ismailov

{"title":"Epidemiology, detection, diagnosis and treatment of TB in children in Kazakhstan.","authors":"O Prikhodchenko, Y Arbuzova, K Serikbayeva, G Zhakhina, A Rakisheva, G Mussabekova, R Akhmedullin, A Tursynbayeva, A Gaipov, M Adenov, S Ismailov","doi":"10.5588/ijtld.24.0536","DOIUrl":"10.5588/ijtld.24.0536","url":null,"abstract":"<sec><title>BACKGROUND</title>TB remains a significant global health challenge, particularly for children, who are often more susceptible to severe disease and complications.</sec><sec><title>METHODS</title>This study provides a comprehensive analysis of TB epidemiology and treatment outcomes in people under 18 years of age in Kazakhstan between 2018 and 2023, utilising a nationwide database that covers the entire country, with a focus on drug-susceptible (DS-TB) and drug-resistant TB (DR-TB) cases.</sec><sec><title>RESULTS</title>During the study period, 3,317 pediatric TB cases were registered, with 76% being DS-TB and a significant proportion being girls and adolescents over 15 years of age. Our findings show a declining trend in TB notification and prevalence from 2018 to 2020, followed by a plateau in subsequent years. According to the data, young children under 5 years of age had the lowest TB caseload. Logistic regression analysis revealed that adolescents of 15-17 years of age had higher odds of unsuccessful treatment, while DR-TB patients had better outcomes than DS-TB patients.</sec><sec><title>CONCLUSION</title>The study highlights the need for targeted interventions, improved diagnostic capabilities, and continuous public health efforts to address the burden of TB in children, especially in high-risk regions.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"29 3","pages":"135-140"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and imaging characteristics associated with hospitalisation for post-TB lung disease. 结核病后肺病住院治疗的临床和影像学特征

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0379

X Li, Z Shi, T Huang, Y Zhou, L Zou, S Tang, G Wu

引用次数: 0

Cross-sectional versus longitudinal estimates of annual risk of TB infection. 结核感染年度风险的横断面与纵向估计。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0492

D A Jolliffe, K Middelkoop, D Ganmaa, D W Dowdy, A R Martineau

引用次数: 0

Supplementary inspired oxygen fraction is a simple clinical tool that predicts clinical deterioration. 补充吸入氧分数是预测临床恶化的一种简单的临床工具。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0474

C J Crooks, J West, J R Morling, M Simmonds, I Juurlink, S Briggs, S Hammond-Pears, D Shaw, T R Card, A W Fogarty

引用次数: 0

Validation of a questionnaire to screen chronic obstructive respiratory diseases. 筛选慢性阻塞性呼吸系统疾病的问卷验证。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0391

H-V T Tran, C T Nguyen, H T Nguyen, I Godin, O Michel

{"title":"Validation of a questionnaire to screen chronic obstructive respiratory diseases.","authors":"H-V T Tran, C T Nguyen, H T Nguyen, I Godin, O Michel","doi":"10.5588/ijtld.24.0391","DOIUrl":"10.5588/ijtld.24.0391","url":null,"abstract":"<sec><title>BACKGROUND</title>Spirometry is the gold standard for diagnosing chronic obstructive respiratory diseases (CORD), but it is not widely available in primary healthcare in Vietnam. We aimed to validate a simple CORD Screening Questionnaire (CORD-SQ) for the Vietnamese population to screen subjects requiring spirometry.</sec><sec><title>METHODS</title>In a cross-sectional study, 589 volunteers seen in a primary healthcare unit were submitted to the CORD-SQ. This questionnaire included four items (cumulative smoking, history of tuberculosis, current breathlessness and wheezing or whistling) with a total score ranging from 0 to 6. The cut-off point of the CORD-SQ was previously determined as a predictor of CORD, which was last defined by spirometry (forced expiratory volume in 1 second/forced vital capacity < lower limit of normal) measured in each subject.</sec><sec><title>RESULTS</title>The prevalence of CORD was 10% among the 517 subjects with non-asthmatic history. With a cut-off point of 2 for the CORD-SQ, the sensitivity and specificity were 69% and 91%, respectively, with a 46% positive predictive value and 94% negative predictive value. The area under the receiver operating characteristic curve of the CORD-SQ to discriminate the CORD was 0.83 (95% CI 0.75-0.90).</sec><sec><title>CONCLUSION</title>In the non-asthmatic Vietnamese primary health care population, the simple CORD-SQ efficiently identifies the people at risk of CORD, requiring spirometry.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"29 3","pages":"113-118"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mobility patterns, activity locations, and TB in Nairobi, Kenya. 流动模式、活动地点和肯尼亚内罗毕的结核病。

IF 3.4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-01 DOI: 10.5588/ijtld.24.0372

K H Tram, J Ong'ang'o, R Kiplimo, T R Hawn, V Nduba, D J Horne, J M Ross

{"title":"Mobility patterns, activity locations, and TB in Nairobi, Kenya.","authors":"K H Tram, J Ong'ang'o, R Kiplimo, T R Hawn, V Nduba, D J Horne, J M Ross","doi":"10.5588/ijtld.24.0372","DOIUrl":"10.5588/ijtld.24.0372","url":null,"abstract":"<sec><title>BACKGROUND</title>Annually, over 3 million people develop TB but are not diagnosed and treated. We aimed to characterize the mobility patterns and activity locations of people with TB in an urban, high-burden setting to inform future active case-finding (ACF) efforts.</sec><sec><title>METHODS</title>We conducted a population-based TB prevalence survey in Nairobi, Kenya, in 2022. Participants aged ≥15 years with TB symptoms or a suggestive chest X-ray submitted sputum for Xpert Ultra and culture. We collected data on individual activity locations and mobility and evaluated their association with the risk of pulmonary TB.</sec><sec><title>RESULTS</title>The prevalence survey enrolled 6,369 participants across nine clusters. There were significant differences in mobility patterns and activity locations between sexes and age groups. Mobility factors were not significantly associated with TB. In the adjusted analysis, age group 45-54 (OR 2.45), male sex (OR 2.95), and use of a social activity location (OR 1.96) were significantly associated with a higher risk of TB.</sec><sec><title>CONCLUSIONS</title>We did not find a significant association between mobility patterns and TB, but there was a positive association between reported 'social' activity locations and TB. Identification of 'social' activity locations, particularly bars, provides important insight into possible venues for spatially-targeted ACF activities.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"29 3","pages":"103-112"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0