O Prikhodchenko, Y Arbuzova, K Serikbayeva, G Zhakhina, A Rakisheva, G Mussabekova, R Akhmedullin, A Tursynbayeva, A Gaipov, M Adenov, S Ismailov
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Epidemiology, detection, diagnosis and treatment of TB in children in Kazakhstan.
BACKGROUNDTB remains a significant global health challenge, particularly for children, who are often more susceptible to severe disease and complications.METHODSThis study provides a comprehensive analysis of TB epidemiology and treatment outcomes in people under 18 years of age in Kazakhstan between 2018 and 2023, utilising a nationwide database that covers the entire country, with a focus on drug-susceptible (DS-TB) and drug-resistant TB (DR-TB) cases.RESULTSDuring the study period, 3,317 pediatric TB cases were registered, with 76% being DS-TB and a significant proportion being girls and adolescents over 15 years of age. Our findings show a declining trend in TB notification and prevalence from 2018 to 2020, followed by a plateau in subsequent years. According to the data, young children under 5 years of age had the lowest TB caseload. Logistic regression analysis revealed that adolescents of 15-17 years of age had higher odds of unsuccessful treatment, while DR-TB patients had better outcomes than DS-TB patients.CONCLUSIONThe study highlights the need for targeted interventions, improved diagnostic capabilities, and continuous public health efforts to address the burden of TB in children, especially in high-risk regions..
期刊介绍：
The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.
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