International journal of surgery最新文献

{"title":"Generative AI (GenAI) model for health forecasting: a new direction to predict the future risk of human disease.","authors":"Chiranjib Chakraborty, Manojit Bhattacharya, Md Aminul Islam","doi":"10.1097/JS9.0000000000003640","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003640","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A commentary on \"The impact of combining regional nerve block with general anesthesia on cognitive function in patients undergoing elbow joint release surgery: a randomized controlled trial\".","authors":"Hairui Wang, Ying Zhang","doi":"10.1097/JS9.0000000000003624","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003624","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor Regarding \"Ferroptosis is involved in the IL-9-induced Intestinal barrier injury in sepsis: an experimental animal and translational study\".","authors":"Peiqi Ying, Yingsong Xu, Yan Li","doi":"10.1097/JS9.0000000000003584","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003584","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor--causes of death after surgery among cancer patients: a population-based cohort study.","authors":"Jing Feng, Peng Su, Yinghao Liu","doi":"10.1097/JS9.0000000000003625","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003625","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor \"Linking immune-inflammation to chronic kidney disease: insights and future research priorities\".","authors":"Yang Liu, Mingjin Xie","doi":"10.1097/JS9.0000000000003643","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003643","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics-based prognostic model for progesterone resistance in endometrial cancer: insights into extracellular matrix and collagen type III.","authors":"Xingchen Li, Jingyuan Wang, Yuman Wu, Aoxuan Zhu, Ruiqi Wang, Jingjing Ji, Xia Yang, Jianliu Wang","doi":"10.1097/JS9.0000000000003629","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003629","url":null,"abstract":"<p><strong>Background: </strong>Progestin resistance in fertility-preserving endometrial cancer (EC) patients remains a significant challenge, and radiomics has not yet been used to predict progestin therapy in these cases.</p><p><strong>Results: </strong>In this study, we constructed a radiomics model to predict progestin resistant for fertility preservation patients. Distribution of clinical features have significant differences in high and low risk of progestin resistant subgroups, which we call predicting-sensitive (PS) vs predicting-resistant (PR) subgroups. The radiomics model achieved high predictive accuracy with an area under the ROC curve (AUC) of 0.841 in the training cohort. We further validate this model in validation and whole cohorts. As a result, the AUCs are 0.873 and 0.852, respectively. Key biological pathways identified include cellular response to external stimulus, collagen metabolic processes, and extracellular matrix (ECM) remodeling. PS was strongly linked to higher collagen type III content and changes in ECM stiffness, which were reflected in altered tumor microenvironment dynamics. Furthermore, fibroblast-epithelial interactions, cytoskeletal organization, and collagen binding were validated by atomic force microscope (AFM) and microfluid equipment with progestin resistance. These findings highlight the influence of ECM remodeling on treatment outcomes.</p><p><strong>Conclusion: </strong>Our radiomics model provides a promising, non-invasive tool for predicting progestin resistance in EC. This approach paves the way for personalized therapeutic strategies for fertility-preserving patients.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Commentary on \"Remote incisions as an alternative to mastectomy scars for breast tissue expander-to-implant exchange: a propensity score-matched analysis\".","authors":"Yuhang Xu, Bo Xu","doi":"10.1097/JS9.0000000000003641","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003641","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Comment on \"Arthroscopic suspension fixation for acute posterior cruciate ligament avulsion fractures in adolescents: a retrospective cohort study\".","authors":"Guandong Chen, Yibing Chen, Weiguo Xu","doi":"10.1097/JS9.0000000000003569","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003569","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative malnutrition and risk of re-revision and mortality following revision arthroplasty.","authors":"Wei Yao, Hong Xu, Xuming Chen, Jing Yang, Fuxing Pei, Duan Wang, Zongke Zhou","doi":"10.1097/JS9.0000000000003550","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003550","url":null,"abstract":"<p><strong>Background: </strong>The impact of preoperative nutritional status on long-term outcomes after revision arthroplasty remains poorly defined. This study aimed to (1) determine the association between preoperative malnutrition and the risks of re-revision and all-cause mortality-distinguishing periprosthetic joint infection (PJI)-related from non-PJI failures-and (2) establish clinically relevant thresholds of the Prognostic Nutritional Index (PNI) for high-risk patient stratification.</p><p><strong>Methods: </strong>In this retrospective cohort study, 1,297 consecutive patients undergoing hip or knee revision arthroplasty between 2008 and 2024 were analyzed. The PNI, calculated from serum albumin and lymphocyte count, was evaluated as both a continuous and categorical variable. Primary outcomes were re-revision (classified as PJI or non-PJI) and long-term all-cause mortality. Analyses included multivariable logistic and Cox regression, restricted cubic spline (RCS) modeling, receiver operating characteristic (ROC) curve analysis, and 1:1 propensity score matching (PSM). Mediation analysis was conducted to assess the inflammatory contribution of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), while the Geriatric Nutritional Risk Index (GNRI) was used for sensitivity analyses in patients aged ≥60 years.</p><p><strong>Results: </strong>Each 1-point reduction in PNI was associated with a 15% higher odds of re-revision (odds ratio [OR] = 1.15; 95% confidence interval [CI], 1.10-1.19; P < 0.001) and a 4% higher hazard of long-term mortality (hazard ratio [HR] = 1.04; 95% CI, 1.01-1.09; P = 0.04), with these associations remaining significant after PSM. The increased re-revision risk was predominantly driven by PJI (OR = 1.19; 95% CI, 1.12-1.25; P < 0.001), with no significant association for non-infectious failures. A PNI threshold of 46.63 optimally predicted re-revision (AUC = 0.72; negative predictive value [NPV] = 0.91), while mortality demonstrated a nonlinear, U-shaped relationship with PNI. ESR partially mediated the PNI-PJI association (mediation effect: 4.36%). GNRI analyses corroborated these findings among elderly patients.</p><p><strong>Conclusions: </strong>Preoperative malnutrition, quantified by PNI, is a robust and independent predictor of re-revision-particularly PJI-related-and long-term mortality following revision arthroplasty. Incorporating PNI-based risk stratification into perioperative care may facilitate targeted nutritional optimization and improve outcomes in this high-risk population.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national burden of appendicitis among children and adolescents from 1990 to 2021 and projection to 2040: a cross-sectional study.","authors":"Ying Huang, Dong Peng, Hongbo Huang, Tingting Wei, Chunyan Luo, Jiaying Li, Aijie Zhang, Ze Zhang, Zheng Gong, Zhiqi Hu, Yichen Wang, Guosheng Ren, Yunhai Li, Fan Li","doi":"10.1097/JS9.0000000000003215","DOIUrl":"10.1097/JS9.0000000000003215","url":null,"abstract":"<p><strong>Background and importance: </strong>Appendicitis is a common surgical emergency in children and adolescents, yet its global epidemiological trends and burden remain understudied. This study aims to analyze the global burden of appendicitis aged 0-19 years from 1990 to 2021.</p><p><strong>Methods: </strong>We extracted data from the Global Burden of Disease 2021 study to analyze the incidence, prevalence, mortality, and disability-adjusted life-years (DALYs) attributable to appendicitis. Age-standardized rates and trends were stratified by sex, age group, region, and socio-demographic index (SDI).</p><p><strong>Results: </strong>In 2021, there were 4.53 million new cases of appendicitis and 360,249 DALYs among children and adolescents globally. The highest age-standardized incidence rate (270.38 [95% UI, 180.93 to 386.54]) was observed in High-SDI region, while the highest mortality rate (0.23 [95% UI, 0.14 to 0.35]) occurred in Low-SDI region. From 1990 to 2021, global age-standardized incidence and prevalence rates decreased slightly, while mortality and DALYs declined substantially. However, the age-standardized incidence and prevalence rates began increasing after 2015 and are projected to rise by over 21% by 2040. Frontier analysis highlighted strong performance in Somalia and Niger among low-SDI countries, whereas the United States Virgin Islands, a high-SDI region, exhibited considerable potential for improvement.</p><p><strong>Conclusions: </strong>The burden of appendicitis among children and adolescents remains significant, with pronounced inequalities across SDI levels. Addressing these inequities requires targeted interventions, such as improving surgical infrastructure in low-SDI regions and optimizing resource utilization in high-SDI regions. These findings provide a foundation for evidence-based policies to ensure equitable care for this vulnerable population.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}