International Journal of Psychiatry in Clinical Practice最新文献

{"title":"Profiles of lithium prescriptions and serum concentrations among patients with bipolar disorder based on latent variable analysis.","authors":"Yuanhan Bai, Jindong Chen, Lina Wang, Zuowei Wang, Xinhua Shen, Jing Sun, Haichen Yang, Tiebang Liu","doi":"10.1080/13651501.2026.2624029","DOIUrl":"10.1080/13651501.2026.2624029","url":null,"abstract":"<p><strong>Background: </strong>The advantages of lithium in treating bipolar disorder (BD) are inconsistent with a declining trend in lithium prescriptions worldwide. Understanding lithium prescription patterns and serum concentrations could improve lithium clinical practices.</p><p><strong>Methods: </strong>This multicentre study used latent variable analysis to explore lithium prescription patterns and changing trends in lithium serum concentrations. A regression model was used to identify their underlying associated factors.</p><p><strong>Results: </strong>High- and low-dose prescription patterns were discovered in patients with mania and bipolar depression (BD-D), respectively. Patients with BD-D tended to receive lower lithium dosages. Lithium combination therapy was mainstream for BD. Factors associated with prescription patterns differed between patients with mania and BD-D. The lithium concentration-to-dose (C/D) ratio initially decreased but then increased. The final lithium serum concentration was mainly associated with dose titration.</p><p><strong>Conclusions: </strong>In this study, lower lithium dosage combined with second-generation antipsychotics is commonly used in the treatment of BD, and lithium prescription patterns fail to follow the guideline recommendations for BD. There are episode-specific factors associated with lithium prescriptions. A non-linear trend in the C/D ratio appears to be one of the factors contributing to lithium delay effects. Adjusting the lithium dosage is a direct way to change its serum concentration. Key PointsLower lithium dosage combined with SGAs is commonly used in the treatment of BD, and lithium prescription patterns fail to follow the guideline recommendations for BD.Factors associated with lithium prescription patterns differed between patients with mania and BD-D.In the context of a standardised lithium dosage (1 g), lithium plasma levels initially decrease before gradually increasing, which appears to be one of the factors contributing to lithium delay effects.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"215-224"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors for predicting response to electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS) and ketamine in patients with treatment-resistant depression: a systematic review.","authors":"Daniel Pustay, Vishal Patel, Krista Ulisse, Jourdan Aromin","doi":"10.1080/13651501.2026.2623198","DOIUrl":"10.1080/13651501.2026.2623198","url":null,"abstract":"<p><strong>Background: </strong>Treatment-resistant depression (TRD) remains a complex challenge, often requiring interventions beyond standard medications. This review explores factors that may predict positive response to electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS) and ketamine-based treatments to help guide clinical decision-making.</p><p><strong>Methods: </strong>A systematic review was conducted following PRISMA 2020 guidelines. English-language, peer-reviewed studies were identified through PubMed, Embase and Google Scholar using search terms such as 'treatment-resistant,' 'outcome,' 'prediction,' 'ECT,' 'rTMS,' and 'ketamine.' Studies were included if they examined clinical, biological or imaging predictors of response in adults with TRD. Case reports, reviews, editorials and non-English articles were excluded. A total of 42 studies were selected from 408 screened.</p><p><strong>Results: </strong>Among these, 23 focused on ketamine/esketamine, 14 on rTMS, and 11 on ECT. Predictive factors were grouped into clinical (e.g., symptom profile, illness duration), biological (e.g., IL-6, CRP, BDNF) and imaging (e.g., cingulate cortex activity, connectivity). Inflammation markers and fronto-limbic network findings appeared across treatments, though findings were inconsistent.</p><p><strong>Discussion: </strong>While some predictors show promise, clinical use remains limited by methodological differences and small sample sizes. Larger studies are required to identify clinically useful predictors. Additionally, for optimal treatment decision-making, comparative studies are necessary.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"140-148"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global burden of anxiety disorders in adolescents and young adults aged 10-24 years from 1990 to 2021.","authors":"Bin Tang, Yuqing Zhu, Qifan Xiao, Mande Kang","doi":"10.1080/13651501.2026.2614011","DOIUrl":"10.1080/13651501.2026.2614011","url":null,"abstract":"<p><strong>Objective: </strong>Anxiety disorders represent a major and growing global health issue, particularly among adolescents and young adults. This study analyzes the burden and trends of anxiety disorders in individuals aged 10-24 from 1990 to 2021.</p><p><strong>Methods: </strong>Using data from the Global Burden of Disease Study 2021, we examined global, regional, and national incidence, prevalence, and disability-adjusted life years (DALYs) for anxiety disorders. Analyses were stratified by gender and age, and the association with the sociodemographic index (SDI) was assessed.</p><p><strong>Results: </strong>The global burden of anxiety disorders in youth increased overall, with a sharp rise after 2019. In 2021, there were 16.67 million new cases globally among 10-24-year-olds, a 52% increase since 1990. Females consistently bore a higher burden than males (incidence rate: 1062.86 vs. 712.09 per 100,000). India, China, and the USA had the highest number of cases. A weak positive correlation was found between SDI and anxiety disorder burden.</p><p><strong>Conclusions: </strong>The escalating burden of anxiety disorders among global youth necessitates enhanced mental health education, public awareness, and targeted interventions. School-based mental health literacy programs and expanded telehealth services are urgently needed, especially in low- and middle-income countries. Further research into mechanisms and equitable access to care is crucial.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"180-194"},"PeriodicalIF":2.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-based prevention of gambling dual disorder through clinical neuroscience and precision psychiatry.","authors":"Nestor Szerman, Francisco Ferre, Yatan Pal Singh Balhara, Marcela Waisman, Pinhas Danon, Pablo Vega, Ignacio Basurte-Villamor, Min Zhao, Ruben Baler","doi":"10.1080/13651501.2026.2621881","DOIUrl":"10.1080/13651501.2026.2621881","url":null,"abstract":"<p><strong>Objective: </strong>Gambling is a common activity that becomes problematic in some vulnerable individuals, with gambling disorder (GD) now recognised as a bona fide mental/brain disorder. Several factors are associated with vulnerability to developing GD, including other mental disorders and pathological personality traits like high impulsivity. This clinical condition, referred to as Dual Gambling Disorder (GDD), better captures the broader psychopathological spectrum of GD.</p><p><strong>Methods: </strong>This narrative review addresses recent advances in neuroscience and psychiatry that can help design more effective prevention strategies for GD. After establishing the current state of the art regarding GD/GDD from a biopsychosocial perspective, we assess the scientific evidence supporting approaches to GDD prevention.</p><p><strong>Results: </strong>Following an overview of GD/GDD, we examine how precision psychiatry can not only shape therapeutic interventions but also, evidence-based prevention strategies for GD, and how these strategies align with advances in clinical neuroscience and precision psychiatry. Prevention is analyzed across multiple levels: primordial, primary, secondary, and tertiary. Finally, we outline key elements to be considered when designing scientifically grounded prevention strategies for specific target populations.</p><p><strong>Conclusions: </strong>The development of preventive strategies for GD, particularly when arising alongside other mental disorders, must be grounded in scientific evidence from neuroscience and precision psychiatry.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"129-139"},"PeriodicalIF":2.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic profiles mediate insomnia-related cognitive impairments in schizophrenia: a large-scale study.","authors":"Linxuan Wang, Yanzhe Li, Yanping Wang, Jingxuan Liu, Yuxin Han, Lijun Wang, Wenjie Sun, Lili Wang, Shen Li","doi":"10.1080/13651501.2025.2581683","DOIUrl":"10.1080/13651501.2025.2581683","url":null,"abstract":"<p><strong>Background: </strong>Insomnia has a significant impact on metabolic changes and cognitive impairments in schizophrenia (SCZ) patients. This study aimed to explore these relationships in SCZ patients.</p><p><strong>Methods: </strong>A total of 609 SCZ patients were recruited. Insomnia was assessed using a self-reported questionnaire with three questions. The psychopathology and cognitive functioning were assessed using the Positive and Negative Syndrome Scale (PANSS) and the Repeated Battery for Assessment of Neuropsychological Status (RBANS), respectively.</p><p><strong>Results: </strong>SCZ patients with insomnia exhibited lower diastolic blood pressure (DBP), higher total cholesterol (TC) and poorer cognitive performance in language, attention, delayed memory and RBANS total score compared to those without insomnia (all <i>p</i> < 0.05). In SCZ patients with insomnia, fasting glucose contributed to immediate memory and RBANS total scores (all <i>p</i> < 0.05). In SCZ patients without insomnia, fasting glucose contributed to immediate memory (Beta = 0.223, <i>t</i> = 4.462, <i>p</i> < 0.001), triglycerides and DBP to visuospatial/constructional (all <i>p</i> < 0.05), and triglycerides to delayed memory (Beta = 0.118, <i>t</i> = 2.060, <i>p</i> = 0.040).</p><p><strong>Conclusions: </strong>Our findings underscore the importance of addressing both metabolic and cognitive factors in SCZ patients with insomnia.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"40-47"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145451814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric evaluation and personality in psoriasis patients.","authors":"Hacer Akgül Ceyhun, Handan Bilen, Ümran Öner, Celalettin Kartal, Fatma Tuygar Okutucu","doi":"10.1080/13651501.2025.2585886","DOIUrl":"10.1080/13651501.2025.2585886","url":null,"abstract":"<p><strong>Objectives: </strong>Psoriasis is a chronic inflammatory, autoaggressive disease. It is known that psychiatric comorbidity in psoriasis contributes to the progression and exacerbation of the disease. This study aims to examine psychiatric disorders and personality traits in a sample of patients with psoriasis.</p><p><strong>Methods: </strong>Personal information forms, General Health Questionnaire (GHQ-12), Hospital-Anxiety-Depression Scale (HADS), Five-Factor Personality Inventory Short Form (BFI) were used for all participants. Psoriasis patients were evaluated with clinical information form, Dermatology Life Quality Index (DLQI), and psoriasis-area-severity-index (PASI). Psychiatric disorders were investigated with the Structured-Clinical-Interview for DSM-IV (SCID) diagnosis.</p><p><strong>Results: </strong>A total of 129 participants completed the case-control study. Psoriasis patients' HADS-total score showed positive correlation with the PASI and DLQI score. SCID interview was conducted with 39(66.1%) psoriasis patients with GHQ-12 score of ≥2, and 25 patients (42.4%) received at least one psychiatric diagnosis. Conscientiousness, agreeableness, and stability were higher in patients with psoriasis than in healthy controls. In psoriasis patients with a psychiatric diagnosis, Plasticity, and Openness to experience personality traits scores showed a significant decrease with a medium effect size. In psoriasis patients without a psychiatric diagnosis, high stability scores were associated with positive emotionality and social well-being, while low plasticity levels were determined as predictors of psychopathology.</p><p><strong>Conclusion: </strong>In improving the quality of life of psoriasis patients, it is important to plan effective treatments for both psoriasis and psychopathology and to evaluate biological vulnerabilities such as personality traits in terms of the risk of comorbid psychopathology.</p><p><strong>Keypoints: </strong>In psoriasis patients with a psychiatric diagnosis, Plasticity, and Openness to Experience personality traits scores showed a significant decrease with a medium effect size.Plasticity predicted psychiatric diagnosis significantly, and negatively in psoriasis patients.In psoriasis patients without a psychiatric diagnosis, high stability scores were associated with positive emotionality and social well-being, while low plasticity levels were determined as predictors of psychopathology.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"48-56"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145633331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of schizophrenia patients in acute setting - a multinational survey of prescription patterns in five European countries.","authors":"Miquel Bioque, Andrea Amerio, Libor Ustohal, Małgorzata Urban-Kowalczyk, Petros Petrikis, Elena Alvarez-Barón, Irene Gabarda-Inat","doi":"10.1080/13651501.2025.2594101","DOIUrl":"10.1080/13651501.2025.2594101","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the use of antipsychotics for first-episode of psychosis (FEP) and relapsed schizophrenia, and the impact of predominant symptoms on decision making.</p><p><strong>Methods: </strong>A survey among 150 European psychiatrists was conducted using computer-assisted web interviewing to assess preferred medications, switching, dose adjustments, and maintenance therapy in acute FEP and relapse settings.</p><p><strong>Results: </strong>Negative or affective symptoms were reported as prevalent in 55% of FEP and 59% of relapsed schizophrenia cases, indicating significant unmet treatment needs. Olanzapine and risperidone were the most commonly prescribed antipsychotics for FEP, with treatment choices influenced by symptom profiles. Long-acting injectables (LAIs) were prescribed to 28% of FEP patients, with notable variation across countries (15-43%; <i>p</i> < 0.05). During hospitalisation, 41% of patients required therapy adjustments, while discharge decisions were driven by drug tolerability and symptom severity. For relapsed patients, non-adherence was identified as the primary cause of relapse (71%), and olanzapine, risperidone, and aripiprazole were the most prescribed treatments. Post-discharge adjustments for relapsed patients focused on adherence and long-term treatment goals.</p><p><strong>Conclusion: </strong>Despite the prevalence of negative or affective symptoms in FEP and relapsed patients, traditional antipsychotics remain the most prescribed treatments. Non-adherence and variability in LAI usage highlight the need for improved symptom-specific approaches and standardised LAI protocols.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"84-98"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the central auditory nervous system: the relation between emotional difficulties and auditory processing.","authors":"Zahra Hosseini Dastgerdi, Nasrin Gohari, Behnam Ghadimi, Aylin Mellati, Amineh Koravand, Saeid Yazdi-Ravandi","doi":"10.1080/13651501.2025.2585888","DOIUrl":"10.1080/13651501.2025.2585888","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to investigate the relationship between emotional difficulties and auditory processing.</p><p><strong>Methods: </strong>A total of 94 students aged 18 to 30 years participated in this cross-sectional study. After assessing the level of anxiety and depression with Beck questionnaires, the performance of auditory processing was examined with dichotic digit (DDT), pitch pattern (PPST), quick speech in noise tests (QSIN), Digit span tests (DST), such as Digit Span Forward (DSF) and Digit Span Backward (DSB) and hyperacusis questionnaire (HQ).</p><p><strong>Results: </strong>Out of 94 participants, 68 individuals (72.3%) experienced some degree of anxiety and depression. A significant relationship was found between anxiety and HQ. There was no relation between anxiety and DSB, DDT, PPST, and QSIN. There was a significant correlation between depression and QSIN. There was no relationship between depression, HQ, DDT, PPST and DSB. The results indicated that anxiety and depression on their own are not correlated with DSF.</p><p><strong>Conclusion: </strong>This study suggests a weak relationship exists between hyperacusis and anxiety. Moreover, emotional factors like anxiety and depression may not have an impact on certain auditory processing functions.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"57-65"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145495542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An investigation of stress and death anxiety levels of individuals who experienced the earthquake after major earthquakes in Turkey.","authors":"Pınar Aka, Elif Kant, Gülpınar Aslan, İrfan Kaplan","doi":"10.1080/13651501.2025.2589226","DOIUrl":"10.1080/13651501.2025.2589226","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to investigate the stress and death anxiety levels of individuals who experienced the earthquake after the major earthquakes that occurred in the Pazarcık and Elbistan districts of Kahramanmaraş in Turkey on February 6, 2023.</p><p><strong>Methods: </strong>The study, which used a descriptive design, was conducted between May 2023 and July 2023, with 408 individuals who agreed to participate in the study and met the inclusion criteria in the provinces affected by the earthquake. Data were collected through the 'Personal Information Form' including questions about individuals' socio-demographic characteristics, the 'Death Anxiety Scale' and the 'Post-Earthquake Trauma Level Determination Scale'.</p><p><strong>Results: </strong>The Death Anxiety Scale (DAS) mean scores indicated significant differences according to age, gender, and the presence of a personal or family disaster plan (<i>p</i> < 0.05). A significant difference was found between the Post-Earthquake Trauma Level Determination Scale (PETLDS) mean scores according to gender, employment, income level, loss of a relative due to the earthquake, and physical injury during the earthquake (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Results showed that the participants were exposed to a moderate level of death anxiety and a high level of trauma after the earthquake. It was also found that the level of trauma increased with the increase in death anxiety.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"66-71"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145540574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of visual remediation intervention in patients with schizophrenia: an exploratory randomized controlled trial.","authors":"Emine Nur Corum, Emrullah Dundar, Aaron Seitz, Cumhur Tas","doi":"10.1080/13651501.2025.2598272","DOIUrl":"10.1080/13651501.2025.2598272","url":null,"abstract":"<p><strong>Objective: </strong>Previous studies have identified visual perception and functional impairments in individuals with schizophrenia, particularly in areas such as contour integration and contrast sensitivity. These deficits can significantly impact daily functioning and social interactions. This study aims to investigate the impact of a visual remediation intervention (VRI) on visual perception deficits, specifically contour integration and contrast sensitivity, while also assessing its effects on social cognition, visual attention, and disease symptoms.</p><p><strong>Methods: </strong>Forty schizophrenia patients were randomly assigned to a VRI group or control group (treatment as usual). The VRI group completed 30 sessions of the 'Sightseeing' program over 10 weeks. Pre- and post-treatment assessments included measures of social cognition, visual attention, psychopathology, contour integration, and contrast sensitivity.</p><p><strong>Results: </strong>Following intervention, the VRI group showed significant improvements in contrast sensitivity, social cognition, visual attention, and contour integration tasks, along with reduced disease symptoms.</p><p><strong>Conclusions: </strong>The 'Sightseeing' VRI program demonstrated beneficial effects across multiple domains in schizophrenia patients. These findings suggest potential implications for future therapeutic interventions. However, it should be noted that the control group did not receive an intervention or placebo condition, which represents a limitation of the study.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"99-106"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}