{"title":"Comparison between minimally invasive surgery and open surgery in managing localized adrenocortical carcinoma treatment: A retrospective propensity-matched study.","authors":"Xin Zhao, Jiaquan Zhou, Xiaohong Lyu, Yanan Li, Yihong Liu, Yushi Zhang","doi":"10.1111/iju.15678","DOIUrl":"https://doi.org/10.1111/iju.15678","url":null,"abstract":"<p><strong>Background: </strong>It was controversial to use open surgery or minimally invasive surgery (MIS) for adrenocortical carcinoma (ACC). This retrospective study aimed to evaluate the impact on prognosis between MIS and open surgery in patients with clinical stage I-II ACC.</p><p><strong>Methods: </strong>Patients with stage I-II ACC from December 2000 to October 2022 were retrospectively studied. The primary endpoint was recurrence-free survival time calculated by the Kaplan-Meier curves.</p><p><strong>Results: </strong>In total, 95 patients were enrolled in this study (50 open surgery and 45 MIS). Propensity score matching identified 32 matched pairs of patients. Compared with the open surgery group, the MIS group had a shorter median operative time (150.0 vs. 120.0 min, p = 0.014), the lesser median volume of intraoperative blood loss (200.0 vs. 60.0 mL, p = 0.006), lower incidence of postoperative complications (59.4% vs. 28.1%, p = 0.023), and shorter median postoperative length of hospital stay (8.0 vs. 7.0 days, p = 0.001). After a median follow-up time of 20.5 months, no significant differences were observed in the local recurrence rate (62.5% vs. 78.1%), distant metastasis rate (15.6% vs. 6.3%), and median time to recurrence (15.0 vs. 20.0 months) between the two groups. The median recurrence-free survival time between the open surgery and MIS groups did not significantly differ (16.0 vs. 21.0 months).</p><p><strong>Conclusion: </strong>MIS might be a feasible option for treating localized ACC at a high patient's volume center with experienced surgeons.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk scoring system for evaluating pathological upstaging after radical nephroureterectomy for upper tract urothelial carcinoma: A multicenter study in Japan.","authors":"Hiroshi Yamane, Shuichi Morizane, Noriya Yamaguchi, Sumiyo Toji, Katsuya Hikita, Masashi Honda, Kuniyasu Muraoka, Hirofumi Oono, Tadahiro Isoyama, Koji Ono, Takehiro Sejima, Atsushi Takenaka","doi":"10.1111/iju.15681","DOIUrl":"https://doi.org/10.1111/iju.15681","url":null,"abstract":"<p><strong>Objectives: </strong>Accurate preoperative staging of upper tract urothelial carcinoma is often difficult. Therefore, we aimed to investigate the preoperative factors associated with pathological upstaging in patients with upper tract urothelial carcinoma undergoing radical nephroureterectomy and to develop a risk-scoring system to assess pathological upstaging.</p><p><strong>Methods: </strong>This retrospective study enrolled 386 patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy at Tottori University Hospital and affiliated hospitals between January 2015 and December 2021. Patients with clinical tumor stage 4, clinical node +, and those who received neoadjuvant chemotherapy were excluded from the study. The association between preoperative patient factors and pathological upstaging was analyzed. Statistical analyses included the t-test, chi-squared test, and logistic regression analysis.</p><p><strong>Results: </strong>Of the 386 patients, 32 were excluded. Finally, 354 patients were included in this study, of whom 87 (24.6%) were pathologically upstaged. Hydronephrosis, positive urine cytology result, and maximum tumor diameter <30 mm were associated with upstaging. We developed a risk scoring system in which the score was the sum of the number of applicable items for three factors: hydronephrosis, positive urine cytology result, and maximum tumor size <30 mm. The probabilities of ureteral cancer upstaging were 0%, 8.3%, 29.5%, and 50.0% for scores of 0, 1, 2, and 3, respectively.</p><p><strong>Conclusions: </strong>Hydronephrosis, urine cytology, and maximum tumor diameter were associated with pathological upstaging. Our risk-scoring system may be useful in predicting pathological upstaging, especially in patients with ureteral cancer.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial comment on “Dutasteride, a 5 alpha-reductase inhibitor, could be associated with the exacerbation of inflammation in patients with benign prostatic hyperplasia”","authors":"Tomoaki Tanaka M.D., Ph.D., Akinori Minami M.D., Ph.D.","doi":"10.1111/iju.15631","DOIUrl":"10.1111/iju.15631","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"32 2","pages":"157"},"PeriodicalIF":1.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment to “A novel anterior approach toward robotic radical prostatectomy is associated with earlier continence recovery than the conventional approach”","authors":"Yoshifumi Kadono M.D., Ph.D.","doi":"10.1111/iju.15616","DOIUrl":"10.1111/iju.15616","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"32 2","pages":"211-212"},"PeriodicalIF":1.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility and surgical outcomes of simultaneous urethral reconstruction for synchronous urethral strictures.","authors":"Yoshiyuki Furukawa, Akio Horiguchi, Masayuki Shinchi, Kenichiro Ojima, Yuhei Segawa, Kazuki Takekawa, Takahiro Minami, Hakaru Masumoto, Sadayoshi Suzuki, Jumpei Katsuta, Daisuke Watanabe, Keiichi Ito","doi":"10.1111/iju.15664","DOIUrl":"https://doi.org/10.1111/iju.15664","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the feasibility and surgical outcomes of simultaneous urethral reconstruction for synchronous urethral strictures (SUS) and analyze the surgical techniques employed for different stricture combinations.</p><p><strong>Methods: </strong>Twenty-two male patients with SUS who underwent urethral reconstruction between February 2018 and July 2023 were retrospectively reviewed. Stricture locations and lengths were evaluated using cystoscopy and urethrography after urethral rest for at least 3 months. Multiple reconstruction techniques were employed based on stricture characteristics, including anastomotic urethroplasty, substitution urethroplasty, staged urethroplasty, perineal urethrostomy, and deep lateral incision of the bladder neck. Anatomical success was defined as the ability to pass a cystoscope without resistance and void without additional interventions.</p><p><strong>Results: </strong>The median age was 72, with iatrogenic causes accounting for 77.2%. The most common stricture combination was strictures at the penoscrotal junction and proximal bulbar urethra (59.1%). Two (9.1%) had strictures in three locations, and one (4.5%) had strictures in four locations. A total of 15 different combinations of reconstruction techniques were utilized to address various stricture patterns. Overall, 86.4% were treated in one stage. The median operation time was 177 min, and the median blood loss was 72 mL. At a median follow-up of 31 months, anatomical success was achieved at 77.3%. No perioperative complications were observed.</p><p><strong>Conclusions: </strong>Simultaneous repair of SUS is feasible using various reconstructive techniques tailored to each stricture site. The high prevalence of iatrogenic etiology and previous transurethral treatments emphasize the importance of appropriate initial management of urethral strictures.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New year's greeting","authors":"Osamu Ukimura M.D., Ph.D.","doi":"10.1111/iju.15649","DOIUrl":"10.1111/iju.15649","url":null,"abstract":"<p>May this new year of 2025 be one in which all wishes and goals of relatives to the International Journal of Urology (IJU) come true!</p><p>Thanks to all authors and relatives of IJU, IJU has been even promoting during these years. In order to contribute to sustainable significant publication to advance the academic promotion of urological fields, IJU is going to publish the special issue every year in addition to the standard issue. IJU aims to up-to-date urological findings generated from not only Asia but also all over the world through the standard as well as specially scheduled issues, and IJU has played an important role in the progress of the world urological fields by showing outstanding academic activities of the field of urology especially in Asian countries. I would express my sincere appreciation for the excellent support to IJU from all members of the Japanese Urological Association (JUA), Urological Association of Asia (UAA), and the readers of IJU all over the world. Fortunately, there is an increased number of submitted urological case reports to IJU Case Reports, which was recognized as an essential journal of case report in urology in the world.</p><p>Recent developments in the field of urology, from prevention, diagnosis, minimally invasive treatment, new drug therapy, cutting-edge surgery, radiation therapy, and multidisciplinary treatment, have surpassed other fields in progress, and at the same time, there have been remarkable advances in basic research that will support these clinical practices. IJU is the most suitable journal for papers on a wide range of research themes in urology.</p><p>Every year, IJU Editorial Board Meeting has been held at the time of the JUA annual meeting in order to introduce its specific feature and further develop IJU and IJU Case Reports to the JUA and UAA members. The next annual meeting of JUA will be held in Fukuoka in 2025, and then, in Kyoto in 2026. At the time of the IJU Editorial Board Meeting, excellent reviewers and significant authors of highly cited articles will be honored as the “Reviewer of the Year” and “Top cited article award.” From the bottom of my heart, I appreciate their significant contributions and efforts to IJU as well as IJU Case Reports and congratulate hereby.</p><p>In this year 2025, I heartfully look forward to your submission of your valuable articles to standard and/or special issues of IJU and IJU Case Reports.</p><p>None declared.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"32 1","pages":"5"},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iju.15649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"This issue of the International Journal of Urology contains many articles: Two review articles, 11 original articles, four urological notes, and 10 editorial comments","authors":"Takahiro Inoue MD., Ph.D.","doi":"10.1111/iju.15645","DOIUrl":"10.1111/iju.15645","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"32 1","pages":"6"},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khayalethu C S Dlamini, Lance J Coetzee, Kgomotso Mathabe
{"title":"South African single surgeon experience: Comparison of oncological outcomes, robot-assisted radical prostatectomy versus open perineal radical prostatectomy.","authors":"Khayalethu C S Dlamini, Lance J Coetzee, Kgomotso Mathabe","doi":"10.1111/iju.15672","DOIUrl":"https://doi.org/10.1111/iju.15672","url":null,"abstract":"<p><strong>Background: </strong>Studies comparing oncological outcomes between robot-assisted radical prostatectomy (RARP) and open radical prostatectomy (ORP) are often limited by bias because of their multi-institutional and multiple surgeon design. Studies from a single institution and single surgeon are uncommon.</p><p><strong>Objective: </strong>To compare oncological outcomes between RARP and ORP at a single institution by a single surgeon.</p><p><strong>Design, setting and participants: </strong>A retrospective cohort study of 2376 men with localized prostate cancer who underwent either RARP or ORP, from 1995 to 2020 at single institution, by one surgeon was done. The first 100 cases were discounted in both cohorts to account for the learning curve.</p><p><strong>Measurements: </strong>Positive surgical margin (PSM) and biochemical recurrence (BCR) rates were measured for each cohort.</p><p><strong>Results: </strong>A total of 1566 men underwent ORP and 810 underwent RARP. BCR rates of 29.2% were found in the ORP group versus 19.5% in the RARP group (p < 0.001). PSM rates of 15.4% were found in the ORP group versus 9.0% in the RARP group (p < 0.001). A multivariate analysis of preoperative prostate specific antigen (PSA) and tumor stage (T) shows no statistically significant association with recurrence when controlled for surgical technique.</p><p><strong>Conclusions: </strong>RARP produces better oncological outcomes when compared to ORP when performed by one experienced surgeon at a single institution.</p><p><strong>Patient summary: </strong>In this large study of men with prostate cancer still localized to the prostate. We found that better cancer removal and chances of cancer recurrence are reduced by a robot-assisted prostate removal technique, compared to the traditional open technique.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Y-V-plasty for refractory bladder neck stenosis after transurethral prostate surgery.","authors":"Hakaru Masumoto, Akio Horiguchi, Masayuki Shinchi, Kenichiro Ojima, Yuhei Segawa, Kazuki Takekawa, Yoshiyuki Furukawa, Takahiro Minami, Sadayoshi Suzuki, Jumpei Katsuta, Daisuke Watanabe, Keiichi Ito","doi":"10.1111/iju.15676","DOIUrl":"https://doi.org/10.1111/iju.15676","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the surgical and patient-reported outcomes of YV-plasty in patients with refractory bladder neck stenosis (BNS) following transurethral prostate surgery.</p><p><strong>Methods: </strong>This retrospective study reviewed five patients who underwent YV-plasty for BNS between January 2021 and October 2023. The surgical procedure involved a midline lower abdominal incision to expose the bladder neck. A V-shaped incision was made in the anterior bladder wall to create a bladder flap. The bladder neck was then incised from the apex of the V-shape to the healthy urethra, forming a Y-shaped incision. Fibrotic tissue was excised, and the posterior side of the urethra and bladder were anastomosed. The bladder flap was mobilized and sutured to the healthy urethra using 4-0 PDS interrupted sutures. Follow-up assessments included uroflowmetry, postvoid residual urine volume measurement (PVR), and questionnaires on daily pad use and patient satisfaction. Success was defined as cystourethroscope passage through the anastomosis without resistance and no need for additional procedures.</p><p><strong>Results: </strong>The median patient age was 69. All patients had a history of failed endoscopic treatments. The median follow-up was 13 months, with all considered successful. The median postoperative maximum flow rate was 26.6 mL/s, and the median PVR was 12 mL. Postoperatively, two (40%) were pad-free, and three (60%) used 1-2 pads daily. Three (60%) patients were 'very satisfied,' one (20%) 'satisfied,' while one (20%) was 'dissatisfied.'</p><p><strong>Conclusions: </strong>Y-V-plasty is an effective option for refractory BNS, improving urinary function and quality of life.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}