International Journal of Urology最新文献

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Low Frequency of Sexual Intercourse, Discrepancy Between Erectile Function Measures, and Sexual Satisfaction Among Japanese Men Aged 45-64 Years: A Nationwide Cross-Sectional Study. 日本45-64岁男性性交频率低、勃起功能测量差异和性满意度:一项全国性横断面研究
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-10-01 DOI: 10.1111/iju.70684
Hisanori Taniguchi, Seiji Shimada, Shinichiro Fukuhara, Koji Chiba, Tsuyoshi Yoshizawa, Hikaru Tomoe, Masato Shirai, Kazunori Kimura, Eiji Kikuchi, Eri Maeda, Yoshikazu Sato, Atsushi Nagai, Koichi Nagao, Akira Tsujimura, Hidefumi Kinoshita, Haruyuki Sasaki
{"title":"Low Frequency of Sexual Intercourse, Discrepancy Between Erectile Function Measures, and Sexual Satisfaction Among Japanese Men Aged 45-64 Years: A Nationwide Cross-Sectional Study.","authors":"Hisanori Taniguchi, Seiji Shimada, Shinichiro Fukuhara, Koji Chiba, Tsuyoshi Yoshizawa, Hikaru Tomoe, Masato Shirai, Kazunori Kimura, Eiji Kikuchi, Eri Maeda, Yoshikazu Sato, Atsushi Nagai, Koichi Nagao, Akira Tsujimura, Hidefumi Kinoshita, Haruyuki Sasaki","doi":"10.1111/iju.70684","DOIUrl":"https://doi.org/10.1111/iju.70684","url":null,"abstract":"<p><strong>Objectives: </strong>To examine sexual behavior, erectile function, and sexual satisfaction among middle-aged Japanese men using nationwide survey data.</p><p><strong>Methods: </strong>This secondary analysis used data from a 2023 nationwide online survey of male sexual dysfunction in Japan. Men aged 45-64 years were included. Sexual behavior was assessed by frequencies of sexual intercourse and masturbation. Erectile function was assessed using the Sexual Health Inventory for Men (SHIM) and Erection Hardness Score (EHS), with ED defined as EHS ≤ 2. Sexual satisfaction was assessed using the overall satisfaction domain of the International Index of Erectile Function. Multivariable logistic regression identified factors associated with ED.</p><p><strong>Results: </strong>Overall, 2314 men were analyzed (mean age, 53.8 ± 5.6 years). Sexual intercourse was infrequent: 48.1% reported intercourse less than once per year and 35.1% within the past 6 months, whereas 45.9% reported masturbation once or twice weekly. ED prevalence differed substantially by assessment method: 82.1% according to SHIM versus 26.9% according to EHS. Men with EHS-defined ED had significantly lower overall sexual satisfaction scores than those without ED (p < 0.001), although satisfaction scores substantially overlapped. Older age, diabetes mellitus, hypertension, mental illness, and sleep apnea syndrome were independently associated with ED.</p><p><strong>Conclusions: </strong>Among middle-aged Japanese men, the prevalence of ED varied substantially according to the assessment method, while EHS-defined ED was associated with lower overall sexual satisfaction despite substantial overlap in satisfaction scores. These findings support considering both erectile function and subjective sexual satisfaction when assessing sexual health.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149267424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment to Visceral Fat Volume and Inguinal Hernia After Robot-Assisted Radical Prostatectomy: A Three-Dimensional CT Analysis. 机器人辅助根治性前列腺切除术后内脏脂肪量与腹股沟疝:三维CT分析。
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-10-01 DOI: 10.1111/iju.70673
Masaki Shimbo
{"title":"Editorial Comment to Visceral Fat Volume and Inguinal Hernia After Robot-Assisted Radical Prostatectomy: A Three-Dimensional CT Analysis.","authors":"Masaki Shimbo","doi":"10.1111/iju.70673","DOIUrl":"https://doi.org/10.1111/iju.70673","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":"e70673"},"PeriodicalIF":2.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overactive Bladder Pharmacotherapy and Long-Term Care Needs, Dementia, and Frailty in Older Women 老年妇女膀胱过度活动药物治疗和长期护理需求、痴呆和虚弱。
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-30 DOI: 10.1111/iju.70652
Kana Ito, Yoko Sato, Nagato Kuriyama, Yoshihiro Tanaka
{"title":"Overactive Bladder Pharmacotherapy and Long-Term Care Needs, Dementia, and Frailty in Older Women","authors":"Kana Ito,&nbsp;Yoko Sato,&nbsp;Nagato Kuriyama,&nbsp;Yoshihiro Tanaka","doi":"10.1111/iju.70652","DOIUrl":"10.1111/iju.70652","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To examine the associations of anticholinergic agents and β3-adrenergic receptor agonists (β3-agonists) prescribed for overactive bladder (OAB) with worsening long-term care needs, incident dementia, and frailty among older women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Subjects/Patients and Methods</h3>\u0000 \u0000 <p>This retrospective cohort study used the Shizuoka Kokuho Database, a population-based administrative claims database in Japan. Women aged 65–84 years who newly initiated anticholinergic agents or β3-agonists for OAB between 2012 and 2024 and had prescription records consistent with continuous treatment for at least 1 year were included. Follow-up began 12 months after treatment initiation. Stabilized inverse probability of treatment weighting (sIPTW) was used to balance baseline covariates between groups. Primary outcomes were worsening long-term care needs and incident dementia; the secondary outcome was changes in the electronic Frailty Index (eFI). Time-to-event outcomes were analyzed using sIPTW-weighted Cox proportional hazards models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The cohort comprised 1 605 anticholinergic and 2 189 β3-agonist users. After sIPTW, baseline covariates were well-balanced. No significant difference was observed in worsening long-term care needs (hazard ratio [HR], 1.03; 95% confidence interval [CI], 0.87–1.22). Anticholinergic use was associated with a higher risk of claims-defined incident dementia compared with β3-agonist use (HR, 1.49; 95% CI, 1.04–2.13). Median eFI did not differ significantly between the groups during 5 years of follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Among older women with OAB, anticholinergic use was associated with an increased risk of claims-defined incident dementia but not with worsening long-term care needs or frailty compared with β3-agonists. Residual confounding and differential dementia ascertainment cannot be excluded.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depressive Symptom Severity Is Associated With IPSS and ICIQ-SF Scores but Not Overactive Bladder in Japanese Male Never-Smokers 日本不吸烟男性抑郁症状严重程度与IPSS和ICIQ-SF评分相关,但与膀胱过度活动无关。
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-30 DOI: 10.1111/iju.70655
Masanobu Yamazaki, Sahoko Ninomiya, Akihito Hashizume, Teppei Takeshima, Hiroki Ito, Kazuhide Makiyama, Hiroji Uemura, Jun-Ichi Teranishi, Takashi Kawahara
{"title":"Depressive Symptom Severity Is Associated With IPSS and ICIQ-SF Scores but Not Overactive Bladder in Japanese Male Never-Smokers","authors":"Masanobu Yamazaki,&nbsp;Sahoko Ninomiya,&nbsp;Akihito Hashizume,&nbsp;Teppei Takeshima,&nbsp;Hiroki Ito,&nbsp;Kazuhide Makiyama,&nbsp;Hiroji Uemura,&nbsp;Jun-Ichi Teranishi,&nbsp;Takashi Kawahara","doi":"10.1111/iju.70655","DOIUrl":"10.1111/iju.70655","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Lower urinary tract symptoms (LUTS) are common in men and have been linked to mental health, but their relationship with depressive symptoms across the adult age range, including young men, remains unclear. We examined the association between LUTS and depressive symptoms in Japanese men.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using an internet research panel, 4000 never-smoking Japanese men were surveyed. LUTS were assessed with the Overactive Bladder Symptom Score (OABSS), International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), International Prostate Symptom Score (IPSS), and Quality of Life (QOL) index, and depressive symptoms with the Quick Inventory of Depressive Symptomatology, Japanese version (QIDS-J). Scores were compared across QIDS-J severity groups, and multivariable regression was used to adjust for age and household income.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 2568 respondents (mean age 46.6 years), more severe depressive symptoms were associated with younger age (<i>p</i> &lt; 0.001). ICIQ-SF and IPSS increased with QIDS-J severity (both <i>p</i> &lt; 0.001) and remained independently associated after adjustment for age and income (IPSS adjusted <i>β</i> 0.32; ICIQ-SF 0.13; both <i>p</i> &lt; 0.001), whereas OABSS was not associated (<i>p</i> = 0.193). The same pattern was observed in men aged 20–40 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Greater depressive symptom severity was independently associated with higher IPSS and ICIQ-SF scores, but not with OABSS, OAB, or UUI among Japanese male never-smokers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment to Cancer-Control Outcomes of Japanese Versus German Metastatic Hormone-Sensitive Prostate Cancer Patients: A Real-World Cross-Country Comparison of Patients Undergoing Combination Therapies 日本和德国转移性激素敏感前列腺癌患者的癌症控制结果:接受联合治疗的患者的现实世界跨国比较
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-29 DOI: 10.1111/iju.70659
Satoshi Fukata
{"title":"Editorial Comment to Cancer-Control Outcomes of Japanese Versus German Metastatic Hormone-Sensitive Prostate Cancer Patients: A Real-World Cross-Country Comparison of Patients Undergoing Combination Therapies","authors":"Satoshi Fukata","doi":"10.1111/iju.70659","DOIUrl":"https://doi.org/10.1111/iju.70659","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment to Intraoperative Near-Infrared Fluorescence Imaging for Qualitative Perfusion Assessment of the Redundant Renal Pelvis After Renal Pelvic Transection in Robot-Assisted Laparoscopic Pyeloplasty 术中近红外荧光成像对机器人辅助腹腔镜肾盂成形术中肾盆腔横断后多余肾盂定性灌注评估的评论
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-29 DOI: 10.1111/iju.70657
Shugo Yajima, Hitoshi Masuda
{"title":"Editorial Comment to Intraoperative Near-Infrared Fluorescence Imaging for Qualitative Perfusion Assessment of the Redundant Renal Pelvis After Renal Pelvic Transection in Robot-Assisted Laparoscopic Pyeloplasty","authors":"Shugo Yajima,&nbsp;Hitoshi Masuda","doi":"10.1111/iju.70657","DOIUrl":"https://doi.org/10.1111/iju.70657","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment to “Primary Resistance to Immune Checkpoint Inhibitor Combination Therapy in Metastatic Renal Cell Carcinoma: Focus on Nivolumab Plus Ipilimumab” 《转移性肾细胞癌对免疫检查点抑制剂联合治疗的原发性耐药:集中于纳沃单抗和伊匹单抗》的社论评论
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-29 DOI: 10.1111/iju.70658
Hiroshi Hirata
{"title":"Editorial Comment to “Primary Resistance to Immune Checkpoint Inhibitor Combination Therapy in Metastatic Renal Cell Carcinoma: Focus on Nivolumab Plus Ipilimumab”","authors":"Hiroshi Hirata","doi":"10.1111/iju.70658","DOIUrl":"https://doi.org/10.1111/iju.70658","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Baseline Detrusor Overactivity Subtype and Impaired Detrusor Contractility Are Associated With Persistent Detrusor Overactivity After β3-Adrenoceptor Agonist Add-On Therapy in Men With Lower Urinary Tract Symptoms 在有下尿路症状的男性患者中,β3-肾上腺素能受体激动剂附加治疗后,基线逼尿肌过度活动亚型和逼尿肌收缩受损与持续逼尿肌过度活动相关
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-28 DOI: 10.1111/iju.70654
Yoshihisa Matsukawa, Tsuyoshi Majima, Shun Takai, Yushi Naito, Tomokazu Kimura, Shohei Ishida, Shusuke Akamatsu
{"title":"Baseline Detrusor Overactivity Subtype and Impaired Detrusor Contractility Are Associated With Persistent Detrusor Overactivity After β3-Adrenoceptor Agonist Add-On Therapy in Men With Lower Urinary Tract Symptoms","authors":"Yoshihisa Matsukawa,&nbsp;Tsuyoshi Majima,&nbsp;Shun Takai,&nbsp;Yushi Naito,&nbsp;Tomokazu Kimura,&nbsp;Shohei Ishida,&nbsp;Shusuke Akamatsu","doi":"10.1111/iju.70654","DOIUrl":"https://doi.org/10.1111/iju.70654","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify baseline urodynamic factors associated with persistent detrusor overactivity (DO) after β3-adrenoceptor agonist add-on therapy in men with lower urinary tract symptoms (LUTS)/overactive bladder (OAB).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed 270 men with LUTS/OAB despite ≥ 3 months of α1-adrenoceptor antagonist or phosphodiesterase type 5 inhibitor monotherapy. All patients had DO on baseline urodynamics and underwent repeat urodynamic evaluation approximately 3 months after add-on β3-adrenoceptor agonist therapy. Baseline DO was classified as phasic, terminal, or combined. Patients were categorized into the DO disappearance and persistent DO groups. Baseline urodynamic parameters were compared, and logistic regression analyses were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>DO disappeared in 129 patients (47.8%) and persisted in 141 (52.2%). The persistent DO group had significantly lower bladder contractility index (BCI), bladder voiding efficiency (BVE), and bladder outlet obstruction index; the overall DO subtype distribution differed significantly between the groups. In multivariable analysis, with phasic DO as the reference, terminal DO (adjusted odds ratio [OR], 3.08; 95% confidence interval [CI], 1.25–7.59), combined DO (adjusted OR, 4.58; 95% CI, 1.86–11.28), lower BCI (adjusted OR per 10-unit increase, 0.67; 95% CI, 0.55–0.82), and lower BVE (adjusted OR per 10-percentage-point increase, 0.80; 95% CI, 0.66–0.97) were independently associated with persistent DO. The adjusted overall subtype effect was significant (<i>p</i> = 0.004).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A baseline terminal DO component and impaired detrusor contractility were independently associated with persistent DO after β3-adrenoceptor agonist add-on therapy. DO subtype and bladder contractility may help identify a potentially treatment-resistant urodynamic phenotype in men with LUTS/OAB.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 10","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Complementary Roles of the Prostate Health Index and Multiparametric Magnetic Resonance Imaging in Optimizing the Detection of Clinically Significant Prostate Cancer in Patients With Prostate-Specific Antigen Levels Below 10 Ng/mL 前列腺健康指数与多参数磁共振成像在优化前列腺特异性抗原水平低于10 Ng/mL患者临床显著性前列腺癌检测中的互补作用
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-14 DOI: 10.1111/iju.70625
Yoshitaka Sekine, Gaku Arai, Hiroki Kito, Mikio Sugimoto, Masaki Shiota, Hisashi Hasumi, Kazuto Ito, Yoshitomo Kobori, Takako Nakada, Takuma Kato, Akira Yokomizo, Yusuke Ito, Kazuhiro Suzuki, Yasushi Kaji
{"title":"The Complementary Roles of the Prostate Health Index and Multiparametric Magnetic Resonance Imaging in Optimizing the Detection of Clinically Significant Prostate Cancer in Patients With Prostate-Specific Antigen Levels Below 10 Ng/mL","authors":"Yoshitaka Sekine,&nbsp;Gaku Arai,&nbsp;Hiroki Kito,&nbsp;Mikio Sugimoto,&nbsp;Masaki Shiota,&nbsp;Hisashi Hasumi,&nbsp;Kazuto Ito,&nbsp;Yoshitomo Kobori,&nbsp;Takako Nakada,&nbsp;Takuma Kato,&nbsp;Akira Yokomizo,&nbsp;Yusuke Ito,&nbsp;Kazuhiro Suzuki,&nbsp;Yasushi Kaji","doi":"10.1111/iju.70625","DOIUrl":"10.1111/iju.70625","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate complementary roles of Prostate Health Index (phi) and multiparametric magnetic resonance imaging (mpMRI) in detection of any prostate cancer (PC) and clinically significant PC (csPC) and to investigate likelihood of risk stratification for recommending prostate biopsy in men with prostate-specific antigen (PSA) ≤ 10 ng/mL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This exploratory post hoc analysis of the prospective multicenter PROPHET cohort included 108 Japanese men who underwent prebiopsy mpMRI. All MRI findings were retrospectively reviewed by one specialized radiologist and scored using Prostate Imaging Reporting and Data System (PI-RADS) v2.1. csPC was defined as ISUP grade group (GG) of 2–5. Then, the likelihood of risk stratification for detecting any PC and csPC based on PI-RADS categories and a significant [−2]proPSA-related index assessed by receiver operating characteristic (ROC) analyses was retrospectively investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PC was detected in 51 of 108 men (47.2%). The ROC analyses revealed the superiority of phi in detecting PC and csPC. Among men with phi ≤ 36.0 and PI-RADS 1–3, csPC was detected in 2 of 36 men (5.6%), but no GG 3–5 cancers were observed. In contrast, in men with phi &gt; 36.0, the risk of detecting PC/csPC was 42.9% (9/21)/23.8% (5/21), 42.9% (3/7)/42.9% (3/7), and 89.3% (25/28)/71.4% (20/28) in PI-RADS 1–2, 3, and 4–5, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>phi and mpMRI have complementary roles for biopsy decision-making in men with PSA ≤ 10 ng/mL. Men with phi ≤ 36.0 and PI-RADS 1–3 may be candidates for biopsy avoidance, whereas phi &gt; 36.0 may be a high-risk group recommending prostate biopsy regardless of mpMRI findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Registry and Registration No. of the Study/Trial</h3>\u0000 \u0000 <p>This study was registered with the <b>UMIN Clinical Trials Registry (UMIN-CTR), registration number</b> UMIN000047187.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 9","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13574299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148968733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visceral Fat Volume and Inguinal Hernia After Robot-Assisted Radical Prostatectomy: A Three-Dimensional CT Analysis 机器人辅助根治性前列腺切除术后的内脏脂肪量和腹股沟疝:三维CT分析。
IF 2.9 3区 医学
International Journal of Urology Pub Date : 2026-09-09 DOI: 10.1111/iju.70631
Hiroshi Kano, Kouji Izumi, Ryunosuke Nakagawa, Taiki Kamijima, Renato Naito, Tomoyuki Makino, Hiroaki Iwamoto, Hiroshi Yaegashi, Takahiro Nohara, Kazuyoshi Shigehara, Atsushi Mizokami
{"title":"Visceral Fat Volume and Inguinal Hernia After Robot-Assisted Radical Prostatectomy: A Three-Dimensional CT Analysis","authors":"Hiroshi Kano,&nbsp;Kouji Izumi,&nbsp;Ryunosuke Nakagawa,&nbsp;Taiki Kamijima,&nbsp;Renato Naito,&nbsp;Tomoyuki Makino,&nbsp;Hiroaki Iwamoto,&nbsp;Hiroshi Yaegashi,&nbsp;Takahiro Nohara,&nbsp;Kazuyoshi Shigehara,&nbsp;Atsushi Mizokami","doi":"10.1111/iju.70631","DOIUrl":"10.1111/iju.70631","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Low body mass index has been reported as a risk factor for inguinal hernia after robot-assisted radical prostatectomy, but whether this association reflects reduced fat mass or reduced muscle mass remains unclear. This study aimed to determine which three-dimensional computed tomography-derived body composition parameter is associated with postoperative inguinal hernia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed 280 patients who underwent robot-assisted radical prostatectomy between February 2016 and January 2024 and had available preoperative non-contrast computed tomography images. Visceral fat volume, subcutaneous fat volume, and psoas muscle volume were quantified using three-dimensional analysis. Cox proportional hazards models were used to evaluate factors associated with postoperative inguinal hernia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Inguinal hernia occurred in 23 patients (8%). Patients who developed inguinal hernia had lower BMI, visceral fat volume, and subcutaneous fat volume than those who did not, whereas psoas muscle volume did not differ significantly. In the multivariable visceral fat volume model, greater visceral fat volume was associated with a lower risk of inguinal hernia (HR per 1 000-cm<sup>3</sup> increase, 0.597; 95% CI, 0.445–0.800; <i>p</i> &lt; 0.001). In a model including both body mass index and visceral fat volume, visceral fat volume remained significant (HR, 0.626; 95% CI, 0.408–0.961; <i>p</i> = 0.032), whereas body mass index did not.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Lower visceral fat volume was associated with a higher risk of inguinal hernia after robot-assisted radical prostatectomy. These findings may provide insight into the body composition factors relevant to the previously reported association between low body mass index and postoperative inguinal hernia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 9","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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