International journal of ophthalmology最新文献

{"title":"Prevalence of refractive errors in school-aged and preadolescent children in Colombia.","authors":"Diana Garcia-Lozada, Diana Valeria Rey-Rodríguez, Sara Viviana Angulo-Sánchez, Jenny Maritza Sánchez-Espinosa","doi":"10.18240/ijo.2024.12.18","DOIUrl":"10.18240/ijo.2024.12.18","url":null,"abstract":"<p><strong>Aim: </strong>To describe the distribution of refractive errors by age and sex among schoolchildren in Soacha, Colombia.</p><p><strong>Methods: </strong>This was an observational cross-sectional study conducted in five urban public schools in the municipality of Soacha. A total of 1161 school-aged and pre-adolescent children, aged 5-12y were examined during the school year 2021-2022. Examinations included visual acuity and static refraction. Spherical equivalent (SE) was analysed as follows: myopia SE≤-0.50 D and uncorrected visual acuity of 20/25 or worse; high myopia SE≤-6.00 D; hyperopia SE≥+1.00 D (≥7y) or SE≥+2.00 D (5-6y); significant hyperopia SE≥+3.00 D. Astigmatism was defined as a cylinder in at least one eye ≥1.00 D (≥7y) or ≥1.75 D (5-6y). If at least one eye was ametropic, children were classified according to the refractive error found.</p><p><strong>Results: </strong>Of the 1139 schoolchildren included, 50.6% were male, 58.8% were aged between 5 and 9y, and 12.1% were already using optical correction. The most common refractive error was astigmatism (31.1%), followed by myopia (20.8%) and hyperopia (13.1%). There was no significant relationship between refractive error and sex. There was a significant increase in astigmatism (<i>P</i><0.001) and myopia (<i>P</i><0.0001) with age.</p><p><strong>Conclusion: </strong>Astigmatism is the most common refractive error in children in an urban area of Colombia. Emmetropia decreased and myopia increased with age.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2288-2294"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monocyte to high-density lipoprotein cholesterol ratio as a predictor of the activity of thyroid-associated ophthalmopathy.","authors":"Xing-Hong Sun, Xiao-Wen Zhang, Chen Han, Xin Dou, Xue-Ying He, Meng-Ru Su, Feng Jiang, Song-Tao Yuan","doi":"10.18240/ijo.2024.12.16","DOIUrl":"10.18240/ijo.2024.12.16","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the relationship between monocyte to high-density lipoprotein cholesterol ratio (MHR) and the disease activity of thyroid-associated ophthalmopathy (TAO).</p><p><strong>Methods: </strong>A total of 87 patients were classified into two groups based on clinical activity score (CAS) scoring criteria: high CAS group (<i>n</i>=62, the CAS score was ≥3); low CAS group (<i>n</i>=25, the CAS score was <3). In addition, a group of healthy people (<i>n</i>=114) were included to compared the MHR. Proptosis, MHR, average signal intensity ratio (SIR), average lacrimal gland (LG)-SIR, average extraocular muscles (EOM) area from 87 patients with TAO were calculated in magnetic resonance imaging (MRI), and compared between these two groups. Correlation testing was utilized to evaluate the association of parameters among the clinical variables.</p><p><strong>Results: </strong>Patients in high CAS group had a higher proptosis (<i>P</i>=0.041) and MHR (<i>P</i>=0.048). Compared to the healthy group, the MHR in the TAO group was higher (<i>P</i>=0.001). Correlation testing declared that CAS score was strongly associated with proptosis and average SIR, and MHR was positively associated with CAS score, average SIR, and average LG-SIR. The area under the receiver operating characteristic curve (AUC) of MHR was 0.6755.</p><p><strong>Conclusion: </strong>MHR, a novel inflammatory biomarker, has a significant association with CAS score and MRI imaging (average SIR and LG-SIR) and it can be a new promising predictor during the active phase of TAO.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2276-2281"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcapsular scleral fixation of the standard capsular tension ring and in-the-bag intraocular lens implantation for severely subluxated lenses.","authors":"Hong-Zhe Li, Fu-Man Yang, Ze-Hui Zhu, Yin-Ying Zhao, Ping-Jun Chang, Yun-E Zhao","doi":"10.18240/ijo.2024.12.22","DOIUrl":"10.18240/ijo.2024.12.22","url":null,"abstract":"<p><strong>Aim: </strong>To present a technique of transcapsular scleral fixation of the standard capsular tension ring (CTR) through equatorial capsulotomy and in-the-bag intraocular lens (IOL) implantation in subluxated lenses.</p><p><strong>Methods: </strong>This retrospective consecutive case series included patients with subluxated lenses by more than 180 degrees who underwent lens extraction, transcapsular scleral fixation of the standard CTR through equatorial capsulotomy, in-the-bag IOL implantation and with at least 6mo follow-up. Preoperative and postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), complications, and postoperative IOL tilt and decentration were recorded.</p><p><strong>Results: </strong>Nine eyes of 7 patients with a mean follow-up of 11.0±3.7mo were included in this study. The BCVA was significantly improved from 0.64±0.22 logMAR preoperatively to 0.21±0.19 logMAR postoperatively (<i>P</i><0.001). The IOP was within the normal range postoperatively. The mean tilt of the IOL was 4.30°±2.31° (range, 1.0° to 8.9°) and the mean decentration of the IOL was 0.37±0.12 mm (range, 0.14 to 0.50 mm). No visually threatened intraoperative and postoperative complications were detected during the follow-up period.</p><p><strong>Conclusion: </strong>This is a safe and effective surgical technique for managing patients with severely subluxated lenses. It has achieved favorable outcomes with fewer surgical manipulations and less need for advanced capsular support devices.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2321-2326"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral meibomian gland morphological alterations in unilateral herpes simplex keratitis based on artificial intelligence analysis.","authors":"Xin-Xin Yu, Xue-Wen Chen, Qi Dai, Shuang-Qing Wu","doi":"10.18240/ijo.2024.12.01","DOIUrl":"10.18240/ijo.2024.12.01","url":null,"abstract":"<p><strong>Aim: </strong>To explore whether unilateral herpes simplex keratitis (HSK) can cause morphological changes of bilateral meibomian glands (MGs) based on artificial intelligence (AI) analytical system.</p><p><strong>Methods: </strong>In the retrospective study, 29 patients with unilateral HSK and 29 participants matched in terms of age and sex were included as control group. Meibographic images of the upper eyelid using Keratograph 5M and assessed ocular surface parameters including tear meniscus height and tear break-up time. MG density and vagueness values were automatically analyzed and calculated using an AI analytical system. We compared the differences between the affected and the contralateral unaffected eyes in HSK patients, and the normal control eyes. We employed either the paired <i>t</i>-test or the Wilcoxon signed-rank test to compare significant difference between the affected and unaffected eyes in HSK patients or between the HSK group and control group.</p><p><strong>Results: </strong>The MG density was 0.19±0.09 in the HSK-affected eye and 0.18±0.07 in contralateral unaffected eye, which had no significant difference (<i>P</i>=0.616). The MG density between the affected eye with HSK and the normal control group was statistically significant (<i>P</i>=0.028). There was a significant difference in MG density between the contralateral unaffected eye and the normal control group (<i>P</i>=0.012). However, no significant difference in vagueness value was observed between the eye with HSK and the control group or between HSK eye and contralateral eye.</p><p><strong>Conclusion: </strong>The MG density between the HSK-affected eye and the contralateral unaffected eye don't significantly differ, whereas there is a significant decrease in the HSK group compared to that of the normal participants. Unilateral HSV keratitis may suffer from bilateral changes of MG morphology indicating bilateral dry eye. Therefore, the fellow eye of patients with unilateral HSK should be considered a potential case of MG dysfunction, necessitating early treatment for bilateral dry eye in the clinic.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2153-2157"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refraction difference value variations in children and adolescents with different refractive errors.","authors":"Da-Wen Wu, Ze-Yi Yang, Yan Nie, He-Ya Ye, Liang Chen, Long-Qian Liu, Guo-Yuan Yang","doi":"10.18240/ijo.2024.12.11","DOIUrl":"10.18240/ijo.2024.12.11","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the refraction difference value (RDV) variations in children and adolescents with different refractive errors and analyze its correlation with refractive development.</p><p><strong>Methods: </strong>Participants aged 4-16y with different refractive statuses (hyperopia, emmetropia, myopia) underwent comprehensive eye examinations, including spherical equivalent (SE) refraction, axial length (AL), total RDV (TRDV), and RDVs at various eccentricities (0°-15°, 15°-30°, 30°-45°) and quadrants (inferior, superior, nasal, temporal). Statistical analysis involved one-way ANOVA for group comparisons and Pearson correlation for examining relationships between SE/AL and RDVs. Paired <i>t</i>-tests compared quadrant-specific RDVs within groups.</p><p><strong>Results: </strong>Significant difference was found in TRDV (<i>P</i><0.001), RDV15°-30° (<i>P</i>=0.033), RDV30°-45° (<i>P</i><0.001), RDV-inferior (RDV-I, <i>P</i><0.001) and RDV-temporal (RDV-T, <i>P</i><0.001) among hyperopia, emmetropia and myopia group. Pearson correlation analysis revealed a negative correlation of SE with TRDV (<i>P</i>=0.001), RDV30°-45° (<i>P</i>=0.004), RDV-I (<i>P</i>=0.047), and RDV-T (<i>P</i><0.001). The differences between RDV-superior (RDV-S) and RDV-I were statistically significant in all groups (<i>P</i><0.001 for all) and between RDV-T and RDV-nasal (RDV-N) were statistically significant in hyperopia group (<i>P</i><0.001). Within the pre-myopic group, the analysis revealed a negative correlation of SE with RDV-I (<i>P</i>=0.009). Pearson correlation analysis revealed a positive correlation of AL with TRDV (<i>P</i>=0.036), RDV15°-30° (<i>P</i>=0.004), RDV30°-45° (<i>P</i><0.001), RDV-S (<i>P</i>=0.003), RDV-I (<i>P</i><0.001), RDV-T (<i>P</i><0.001), RDV-N (<i>P</i>=0.022), while revealed a negative correlation of AL with RDV0-15° (<i>P</i>=0.018).</p><p><strong>Conclusion: </strong>Our study indicates TRDV, RDV30°-45°, RDV-I, RDV-T may relate to refractive development, and a negative correlation between SE and RDV-I in pre-myopic children.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2236-2242"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of <i>SMOC2</i> gene variants in familial and non-familial primary open angle glaucoma Pakistani patients.","authors":"Ashok Kumar Narsani, Feriha Fatima Khidri, Muhammad Rafiq, Jalpa Bai, Hina Shaikh, Yar Muhammad Waryah, Syed Habib Ahmed Naqvi, Preety Kumari, Mahesh Kumar Lohano, Ali Muhammad Waryah","doi":"10.18240/ijo.2024.12.05","DOIUrl":"10.18240/ijo.2024.12.05","url":null,"abstract":"<p><strong>Aim: </strong>To find out the association of secreted protein acidic and rich in cysteine (SPARC)-related modular calcium binding 2 (<i>SMOC2</i>) gene variants rs2255680 and rs13208776 with genotypic and phenotypic characteristics in both familial and non-familial primary open angle glaucoma (POAG) patients.</p><p><strong>Methods: </strong>A total of 212 POAG patients, comprising 124 familial and 88 non-familial, were enrolled. For genotyping the <i>SMOC2</i> variant rs2255680, amplification refractory mutation system (ARMS)-polymerase chain reaction (PCR) method and PCR-restriction fragment length polymorphism (PCR-RFLP) were utilized for analyzing rs13208776 variant.</p><p><strong>Results: </strong>The mean age of familial POAG patients was 50.92±9.12y, with 78 males and 46 females. The mean age of non-familial POAG patients was 53.14±13.44y, with 52 males and 36 females. The <i>SMOC2</i> gene variant rs13208776 showed the significant association with POAG between familial and non-familial groups. The homozygous G/G variant was frequent among non-familial (60.2%) whereas the heterozygous G/A variant was more frequent in familial POAG patients (46%). There were significant differences in G/A variant between familial and non-familial glaucoma patients, and the risk was decreased to 0.53-fold in non-familial glaucoma patients [odds ratio (OR): 0.53; 95% confidence interval (CI): 0.29-0.94; <i>P</i>=0.033] in codominant model. The risk was further reduced to 0.49-fold (95%CI: 0.28-0.86; <i>P</i>=0.012) in dominant model for non-familial patients. No significant association of <i>SMOC2</i> gene variant rs2255680 between familial and non-familial glaucoma patients was found in our population. The haplotype analysis showed the decreased risk for TA [OR: 0.48 (95%CI: 0.29-0.79); <i>P</i>=0.004] and an increased risk for TG [OR=2.28 (95%CI: 1.22-4.25); <i>P</i>=0.01] haplotypes.</p><p><strong>Conclusion: </strong>Current findings show significant association of <i>SMOC2</i> gene variant rs13208776 with POAG between familial and non-familial Pakistani patients.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2185-2191"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of mycophenolate mofetil combined with topical 0.05% tacrolimus in high-risk keratoplasty: 1-year cohort study.","authors":"Jin-Yu Zhang, Kang Yu, Xiu-Ying Jiang, Jia-Xin Liang, Shi-You Zhou","doi":"10.18240/ijo.2024.12.10","DOIUrl":"10.18240/ijo.2024.12.10","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the efficacy of systemic mycophenolate mofetil (MMF) as an adjunct in combination with topical tacrolimus (FK506) and corticosteroid eyedrops for preventing corneal graft rejection after high-risk keratoplasty (HRK).</p><p><strong>Methods: </strong>In this cohort study, 55 consecutive patients (55 eyes) from an eye center who met the criteria of HRK were included. The definition for HRK includes large grafts of no less than 9 mm diameter, vascularized cornea of two or more quadrants, regrafting, or eccentric grafts. After penetrating keratoplasty, 25 patients treated with systemic MMF in combination with 0.05% FK506 and tapering corticosteroid eyedrops were enrolled in Group 1 from October 2019. Thirty patients receiving postoperative treatment with 0.05% FK506 and tapering corticosteroid eyedrops alone were enrolled in Group 2 from January 2018 to September 2019. All participants were closely monitored after surgery, and episodes of graft rejection and relevant clinical data were collected and assessed over a one-year follow-up period.</p><p><strong>Results: </strong>After a follow-up of 9.6±3.2mo, graft rejection episodes occurred in 4 cases (16%) in Group 1 and 18 cases (60%) in Group 2. One reversible and 3 irreversible graft rejections occurred in Group 1, while 3 reversible and 15 irreversible rejections occurred in Group 2. Kaplan-Meier analysis revealed that 82.5% of grafts in Group 1 and 37.1% in Group 2 did not experience corneal graft rejection (<i>P</i><0.01, log-rank test). The clear graft survival rate was 83.6% in Group 1 and 36.7% in Group 2 (<i>P</i><0.01, log-rank test) within one year of follow-up. No severe systemic side effects were observed in either group during the follow-up period.</p><p><strong>Conclusion: </strong>The triple treatment regimen consisting of MMF, topical FK506, and corticosteroid eyedrops represents a promising strategy for effectively preventing graft rejection and improving graft survival in patients with HRK.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2229-2235"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alkali burn injury model of meibomian gland dysfunction in mice.","authors":"Yong Li, Ya-Qiong Yang, Yong Lin, Ke Yan, Yu-Fei Lyu, Zhao-Qiang Zhang, Cai-Hong Huang, Jiao-Yue Hu, Zu-Guo Liu","doi":"10.18240/ijo.2024.12.02","DOIUrl":"10.18240/ijo.2024.12.02","url":null,"abstract":"<p><strong>Aim: </strong>To establish a stable, short-time, low-cost and reliable murine model of meibomian gland dysfunction (MGD).</p><p><strong>Methods: </strong>A filter paper sheet soaked in 1.0 mol/L sodium hydroxide (NaOH) solution was used to touch the eyelid margin of C57BL/6J mice for 10s to establish the model. The other eye was left untreated as a control group. Eyelid margin morphological changes and the meibomian glands (MGs) were observed by slit lamp microscopy on days 5 and 10 post-burn. Hematoxylin-eosin (HE) staining and Oil red O staining were adopted in detecting the changes in MGs morphology and lipid deposition. Real-time polymerase chain reaction, Western blot, immunofluorescence staining and immunohistochemical staining were used to detect interleukin (IL)-6, IL-1β, IL-18, tumor necroses factor (TNF)-α, interferon (IFN)-γ, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4), 3-nitroturosine (3-NT), 4-hydroxynonenal (4-HNE) and cytokeratin 10 (K10) expression changes in MGs.</p><p><strong>Results: </strong>MGs showed plugging of orifice, glandular deficiency, abnormal acinar morphology, ductal dilatation, and lipid deposition after alkali burn. The expressions of IL-6, IL-18, IL-1β, IFN-γ, and TNF-α indicators of inflammation and oxidative stress in MGs tissues were significantly increased. Abnormal keratinization increased in the MG duct.</p><p><strong>Conclusion: </strong>A murine model of MGD is established by alkali burn of the eyelid margin that matches the clinical presentation of MGD providing a stable, short-time, low-cost, and reliable MGD model. The new method suggests efficient avenues for future research.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2158-2166"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of corneal aberration in patients with bilateral keratoconus and unilateral corneal Vogt's striae.","authors":"Sheng-Sheng Wei, Yong Li, Zhi-Qing Wu, Jian-Guo Liu, Jing Du, Jing Li, Yao-Hua Zhang","doi":"10.18240/ijo.2024.12.21","DOIUrl":"10.18240/ijo.2024.12.21","url":null,"abstract":"<p><strong>Aim: </strong>To assess the corneal high-order aberration (HOA) and its correlation with corneal morphological parameters in patients with bilateral keratoconus (KCN) and unilateral Vogt's striae.</p><p><strong>Methods: </strong>A total of 168 eyes of 84 patients with KCN, whose corneas had definite signs of unilateral Vogt's striae, were enrolled. Corneal HOA and morphological parameters were measured using Pentacam HR.</p><p><strong>Results: </strong>The corneal morphological parameters between KCN eyes with and without Vogt's striae were evidently different (<i>P</i><0.001). The 3^rd coma 90°, 4^th spherical aberration, 5^th coma 90°, root-mean-square (RMS) (total), and RMS (HOA) in the front, back surfaces and total cornea in KCN eyes with Vogt's striae were significantly higher than those in KCN eyes without Vogt's striae (<i>P</i><0.001). In KCN eyes with Vogt's striae, the 3^rd coma 90° and 4^th spherical aberration in the front surface and total cornea were negatively correlated with flat keratometry value (K1), steep keratometry value (K2), mean keratometry value (Km), maximum keratometry value (Kmax), anterior corneal elevation (ACE), and posterior corneal elevation (PCE; <i>P</i><0.05). The 3^rd coma 90°, 4^th spherical aberration in back surface and RMS (total), RMS (HOA) in the front, back surfaces, total cornea were positively correlated with K1, K2, Km, Kmax, ACE, and PCE (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Corneal HOA especially vertical coma and spherical aberration may increase when Vogt's striae appeared in KCN eyes. The scale of increase is significantly related with changes in corneal shapes.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2316-2320"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirty-gauge needle-guided purse-string suture pupilloplasty: a new technique.","authors":"Chun-Ming Chen, Hong Zhong, Yan Shao, Cheng-Yao Qin, Ze-Hao Liu, Wen-Xiu Sun, Min Li","doi":"10.18240/ijo.2024.12.23","DOIUrl":"10.18240/ijo.2024.12.23","url":null,"abstract":"<p><strong>Aim: </strong>To observe the clinical outcomes of 30-gauge (G) needle-guided 10-0 prolene suture purse-string pupilloplasty for atonic pupil management.</p><p><strong>Methods: </strong>Eight patients with atonic pupils who underwent suture purse-string pupilloplasty were retrospectively analyzed. Preoperative data and at least 6mo of postoperative data were collected from all the patients.</p><p><strong>Results: </strong>The corrected distance visual acuity (CDVA) before and after surgery was 0.58±0.22 and 0.20±0.10 logMAR, respectively (<i>P</i>=0.002). The pre- and postoperative pupil size was 7.38±0.88 and 3.09±0.71 mm (<i>P</i>=0.000), respectively. The corneal endothelial cell count was 2841±176/mm² before and 2692±143/mm² after surgery (<i>P</i>=0.000). No intraoperative or postoperative complications were reported. During the follow-up period of at least 6mo, all treated pupils were centered and generally or nearly round. Furthermore, the patients did not exhibit photophobia, glare, or diplopia.</p><p><strong>Conclusion: </strong>This technique is a simple and effective method for pupil reduction.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"17 12","pages":"2327-2332"},"PeriodicalIF":1.9,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}