{"title":"Preconception body mass index is associated with the risk of spontaneous preterm birth among women with gestational diabetes: A retrospective cohort study.","authors":"Yuan Yuan, Shuting Yu","doi":"10.1002/ijgo.70056","DOIUrl":"https://doi.org/10.1002/ijgo.70056","url":null,"abstract":"<p><strong>Objective: </strong>Prior research efforts have not effectively clarified the relationship between preconception body mass index (BMI) and spontaneous preterm birth among women with gestational diabetes mellitus (GDM), particularly among Asian women. This study explores the relationship between pre-pregnancy BMI and spontaneous preterm birth among women with GDM, taking into account triacylglycerol (TG), glycated hemoglobin A1c (HbA1c), and gestational weight gain (GWG) levels.</p><p><strong>Method: </strong>Data from 1116 women with GDM who produced singleton live births were retrospectively analyzed. Logistic regression models were used to explore the relationship between pre-pregnancy BMI and spontaneous preterm birth.</p><p><strong>Results: </strong>Relative to women with GDM with a BMI in the normal range, those who were overweight/obese exhibited a significantly higher risk of spontaneous preterm birth. This link between BMI and spontaneous preterm birth risk varied as a function of GWG, HbA1c, and TG. Specifically, among those women who were overweight/obese prior to pregnancy, TG levels were significantly related to spontaneous preterm birth risk at TG concentrations exceeding 1.69 mmol/L. Notably, the combination of overweight/obese status, excessive GWG, and/or HbA1c levels ≥5.5% was associated with a higher risk of spontaneous preterm birth relative to overweight/obese status alone.</p><p><strong>Conclusion: </strong>These data show that preconception BMI is significantly linked to the risk of spontaneous preterm birth among Chinese GDM patients. When examining this relationship, HbA1c, TG, and GWG levels should be taken into consideration.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: Postoperative pain control and opioid use with transversus abdominis plane block and scheduled multimodal pain management in patients undergoing cesarean section.","authors":"Ning Cong, Yan-Hua Guo, Fu-Shan Xue","doi":"10.1002/ijgo.70071","DOIUrl":"https://doi.org/10.1002/ijgo.70071","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of life and sexual health of women with peripartum hysterectomy: A single-center experience from South India.","authors":"Nivedita Jha, Pavani Manikya Palepu, Veena Pampapati, Moushumi P Mukherjee, Kayathri Karthikeyan, Manoharan Anuja, Kirti Girish Deodhare, Kumari Pannirselvan","doi":"10.1002/ijgo.70058","DOIUrl":"https://doi.org/10.1002/ijgo.70058","url":null,"abstract":"<p><strong>Objective: </strong>The quality of life and psychosomatic consequences of peripartum hysterectomy (PH) have not been studied in a larger cohort. Therefore, the present study aimed to evaluate the quality of life, social and sexual functions in women who underwent peripartum hysterectomy.</p><p><strong>Methods: </strong>In this retrospective cohort study, women who underwent PH from July 2016 to June 2021 were identified. Women who had a cesarean delivery (CD) in the same period were chosen as controls. The WHO quality of life (brief version) (WHOQOL-BREF), evaluation of social system (EVOS) scale, and Arizona sexual experience scale (ASEX) were utilized to assess quality of life, sexual satisfaction and social health.</p><p><strong>Results: </strong>A total of 75 women in PH and 75 in the CD group completed WHOQOL-BREF, while only 53 women completed ASEX and EVOS. The mean age was 29.13 ± 4.5 and 27.69 ± 4.38 years in the PH and CD group, respectively. General quality of life and health were significantly lower in the PH group (mean difference [95% CI], -27.16 [-33.80-20.54]; P = 0.000). No significant difference was observed in the physical (62.52 ± 14.9 vs. 64.52 ± 12.62; P = 0.376) and social domain (70.44 ± 15.33 vs. 70.77 ± 14.84; P = 0.893) of QOL. However, in the psychological (47.61 ± 11.76 vs. 54.77 ± 11.67; P = 0.000) and environmental domain (59.79 ± 8.61 vs. 65.29 ± 10.61; P = 0.001), significantly lower scores were observed in women with PH. The ASEX score was comparable (17.51 ± 5.83 vs. 17.8 ± 4.82; P = 0.745).</p><p><strong>Conclusion: </strong>The overall quality of life and psychological health are inferior in women who have had a peripartum hysterectomy. However, physical function and sexual satisfaction are comparable to those who had a cesarean delivery.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Restaino, Federico Paparcura, Martina Arcieri, Alice Poli, Giulia Pellecchia, Giorgio Bogani, Cristina Taliento, Luigi Della Corte, Federica Perelli, Jvan Casarin, Salvatore Gueli Alletti, Tiziana Bove, Teresa Dogareschi, Lorenza Driul, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli
{"title":"Postoperative pain after MiniLap percutaneous versus standard laparoscopic salpingo-oophorectomy: A propensity-matched study.","authors":"Stefano Restaino, Federico Paparcura, Martina Arcieri, Alice Poli, Giulia Pellecchia, Giorgio Bogani, Cristina Taliento, Luigi Della Corte, Federica Perelli, Jvan Casarin, Salvatore Gueli Alletti, Tiziana Bove, Teresa Dogareschi, Lorenza Driul, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli","doi":"10.1002/ijgo.70060","DOIUrl":"https://doi.org/10.1002/ijgo.70060","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare postoperative outcomes in patients undergoing standard laparoscopic salpingo-oophorectomy versus those using the MiniLap percutaneous surgical system, aiming to demonstrate the non-inferiority of this ultra-minimally invasive surgical technique compared to the current gold standard.</p><p><strong>Methods: </strong>This was a retrospective, single-center propensity-matched case-control study. A total of 80 surgical patients undergoing salpingo-oophorectomy for benign pathology were selected, with 40 in each group (MiniLap in group A and S-LPS in group B). Postoperative pain was subjectively reported at 2, 4, 12, and 24 h after surgery. The secondary outcomes of this study were to evaluate differences in the duration of surgery, intraoperative blood loss, postoperative complications, and cosmetic results.</p><p><strong>Results: </strong>The median operative time was 57.7 min (range, 28-125) in group A and 75.5 min (range, 22-180) in group B (P value 0.005). No statistical differences were recorded in terms of estimated blood loss (P value 0.05), length of hospital stay (P value 0.74), complications (P-value 0.31), and postoperative pain (P value 0.06 at 2 h postoperatively). Cosmetic outcomes acquired through subjective assessment by the patient and surgeon at discharge and 1 month after surgery demonstrated a statistically significant higher satisfaction rate in the MiniLap compared to the S-LPS group.</p><p><strong>Conclusion: </strong>Our study demonstrates that salpingo-oophorectomy performed with the MiniLap system is feasible, safe, and well-tolerated by patients. Furthermore, this technique has proven to be non-inferior to standard LPS in terms of postoperative pain, blood loss, hospital stay duration, and complications.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Premature ovarian insufficiency, the unrecognized cause of sub-fertility in Africa.","authors":"Bruno Bongo, Charles Muteshi","doi":"10.1002/ijgo.70067","DOIUrl":"https://doi.org/10.1002/ijgo.70067","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosing polycystic ovary syndrome at a tertiary level hospital in Latin America.","authors":"Julieth Alexandra Guzmán López, Oscar Eduardo Rivera Contreras, Fabián Manrique Hernández, Jenny Alison González Moreno, Herwing Caicedo León, Valentina Cáceres Valero, Andrea Juliana Sepúlveda Sanguino, Andrés Sebastián Torres, Janer Sepúlveda Agudelo","doi":"10.1002/ijgo.70026","DOIUrl":"https://doi.org/10.1002/ijgo.70026","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is the most common neuroendocrine disorder in women of reproductive age. There is little consensus on the diagnosis of this syndrome, which affects both the number of cases that are diagnosed and the respective consequences. The aim of the present study was to evaluate the degree to which currently established criteria for diagnosing polycystic ovary syndrome are followed at a tertiary-level hospital in Colombia. Cross-sectional, observational, analytical study of patients diagnosed with PCOS between 2012 and 2019. A statistical analysis was performed based on information obtained from clinical histories, using frequencies and percentages for categorical variables and measures of central tendency for continuous variables. A total of 66 patients were included in the study, of which 69.69% (n = 46) sought medical care for abnormal uterine bleeding, 64.9% (n = 37) were found to be overweight or obese, 39.39% (n = 26) had clinical hyperandrogenism and 84.84% (n = 56) presented imaging findings compatible with polycystic ovaries. The ultrasound description was incomplete in the majority of cases. A Ferriman-Gallwey score was used to evaluate 7.57% (n = 5) of the patients, 53.03% (n = 35) were diagnosed without a complete or any exclusion of differential pathologies and 34.85% (n = 23) of the women were diagnosed with PCOS in accordance with currently established criteria. The main causes of the high frequency of diagnosing PCOS in a manner that did not accord with current criteria may have been not having excluded differential pathologies, not applying the established scale for objectively evaluating hirsutism and a lack of specifying follicular counts in imaging reports.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ezgi Başaran, Ecem Haliloğlu, Osman Onur Özkavak, Murat Haksever, Harun Demirci, Özgür Öcal, Atakan Tanaçan, Dilek Şahin
{"title":"Prenatal predictors of ventriculoperitoneal shunt requirement and adverse perinatal outcomes in newborns with open spina bifida.","authors":"Ezgi Başaran, Ecem Haliloğlu, Osman Onur Özkavak, Murat Haksever, Harun Demirci, Özgür Öcal, Atakan Tanaçan, Dilek Şahin","doi":"10.1002/ijgo.70063","DOIUrl":"https://doi.org/10.1002/ijgo.70063","url":null,"abstract":"<p><strong>Objective: </strong>Spina bifida is a group of anomalies that, while non-lethal, require careful prenatal evaluation and prognosis prediction due to their association with common motor and cognitive problems. In this study, we investigated the need for postnatal ventriculoperitoneal shunting (VPS) in fetuses with open spina bifida and explored the relationship between adverse perinatal outcomes and prenatal ultrasonographic findings.</p><p><strong>Methods: </strong>In this retrospective study, fetuses with open spina bifida that were diagnosed prenatally and resulted in a live birth were examined. The fetuses were divided into two groups: those who required VPS and those who did not require VPS in the postnatal period, and their prenatal clinical characteristics (lateral ventricle [LV] width, defect size, and defect level) and postnatal results (Apgar scores, length of hospital stay, lower extremity motor functions, bladder dysfunction, and epilepsy) were compared.</p><p><strong>Results: </strong>Prenatal LV width, defect size, presence of hindbrain herniation, and defect level were significantly different between the groups (all P < 0.05). Similarly, a significant difference was seen when comparing adverse neonatal outcomes; with worse outcomes observed in the group requiring VPS. It was observed that LV width, sac size and hindbrain herniation predicted the need for VPS in univariate analyses (P = 0.002, P = 0.013, P: 0.004, respectively). However, defect level had no predictive effect on VPS requirement.</p><p><strong>Conclusion: </strong>Larger prenatal LV width and sac size were associated with an increased need for postnatal VPS and were effective in predicting adverse perinatal outcomes. Utilizing this information in prenatal counseling and pregnancy management may prove beneficial.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stem cell theory: A new horizon for the treatment of endometriosis by targeting mesenchymal stem cell.","authors":"Wanhui You, Siyu Wang, Chan Li, Yuting Ma, Fangyuan Liu, Ying Shen, Yingdong Wang, Fang Wan, Fengjuan Han","doi":"10.1002/ijgo.70046","DOIUrl":"https://doi.org/10.1002/ijgo.70046","url":null,"abstract":"<p><p>Endometriosis is a prevalent chronic gynecological disease that poses significant challenges for treatment due to its extensive lesions, diverse morphology, unknown etiology, and tendency for recurrence. In the early 21st century, the stem cell theory of endometriosis pathogenesis has offered new insights into its diagnosis and treatment. The stem cell theory posits that the terminal cells in the ectopic lesions are unable to sustain the long-term development of the lesions. Instead, endometrial stem cells (SCs) and SCs from outside the uterus are believed to participate in the formation and development of endometriosis. Notably, mesenchymal SCs (MSCs), which are multipotent SCs derived from the mesoderm, may contribute to the progression and potential malignant transformation of endometriosis through specific mechanisms. Therefore, this paper outlines the pathogenesis of endometriosis and the discovery of the stem cell theory. Additionally, it summarizes recent advancements in understanding the role of MSCs from various sources in endometriosis pathogenesis and proposes intervention strategies targeting MSCs for the treatment of endometriosis.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: Vascular dysfunction in women with recurrent pregnancy loss-Possible association with antiphospholipid antibodies.","authors":"Li E Huo, Ning Li, Yandong Yang","doi":"10.1002/ijgo.70019","DOIUrl":"https://doi.org/10.1002/ijgo.70019","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Announcing the winner of the John J. Sciarra IJGO prize paper award for 2024","authors":"Michael Geary","doi":"10.1002/ijgo.70061","DOIUrl":"https://doi.org/10.1002/ijgo.70061","url":null,"abstract":"<p>The editors of the <i>International Journal of Gynecology & Obstetrics</i> (IJGO) are pleased to announce the winner of the prize paper award for the best clinical research paper from a low- or middle-income country published in IJGO during 2024. The winning paper is: Soares FM, da Rocha Carvalho Rosa LO, Cecatti JG, et al. <b>Design, construction, and validation of obstetric risk classification systems to predict intensive care unit admission</b>. <i>Int J Gynecol Obstet</i>. 2024; 167: 1243–1254. https://doi.org/10.1002/ijgo.15782. It was published in the December 2024 issue of IJGO.</p><p>This award brings with it a stipend of £800, a certificate of recognition, and complimentary access to IJGO for a period of 1 year from the date the prize is awarded.</p><p>All clinical research articles submitted to the IJGO from low- and middle-income countries that were published in 2024 were considered for this prize. The paper was chosen from 181 qualifying articles. Selection and review were undertaken by the editors, and the Editorial Board of IJGO endorsed the decision.</p><p>The winning paper is by Soares et al. The study investigates the development and validation of a machine-learning-based risk classification system to predict intensive care unit (ICU) admission for high-risk pregnant women. Using data from 9550 cases of severe maternal morbidity, machine-learning models were tested on accuracy, sensitivity and specificity. The highest-performing model, XGBoost, estimated ICU admission at 11.6%, lower than the actual 21.5%, suggesting the potential overuse of ICU resources. The findings of this study highlight the potential for AI-driven tools to optimize ICU allocation and improve maternal care.</p><p>Additional papers that are worthy of special recognition are awarded an honorable mention. While the honorable mention recognition does not include a financial award, each author receives a certificate of recognition and a letter of commendation from the editors of IJGO.</p><p>The following 11 papers receive an honorable mention:</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":"169 1","pages":"450-451"},"PeriodicalIF":2.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.70061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}