International Journal of Gynecology & Obstetrics最新文献

{"title":"Letter to the Editor: Reverse Takotsubo induced cardiogenic shock in the peripartum period: A case report and literature review.","authors":"Gonzalo García-Martí, Ravi Vazirani, Iván J Núñez-Gil","doi":"10.1002/ijgo.70489","DOIUrl":"https://doi.org/10.1002/ijgo.70489","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of large-loop excision of the transformation zone on cervical morphology: A prospective observational study.","authors":"Flávia Zero Soares, Silvana Maria Quintana, Helmer Herren, Patrícia Pereira Dos Santos Melli, Marília Veccechi Bijos Zaccaro","doi":"10.1002/ijgo.70447","DOIUrl":"https://doi.org/10.1002/ijgo.70447","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the impact of large-loop excision of the transformation zone (LLETZ) on cervical dimensions, to identify influencing factors on cervical regeneration and to verify the concordance between ultrasonographic techniques for assessing cervical volume.</p><p><strong>Methods: </strong>This was a prospective observational study conducted at the University of São Paulo Clinical Hospital from May 2022 to April 2023. Ultrasonographic measurements of cervical length and volume were obtained before LLETZ and at 3 and 6 months post-procedure. The influence of variables on the regenerative process was evaluated using generalized linear regression models, and the concordance between volume measurements using the cylinder formula and VOCAL (Virtual Organ Computer-Aided Analysis) software was assessed.</p><p><strong>Results: </strong>The mean cervical length decreased from 32.3 mm to 30.3 mm at 3 months but increased to 31.7 mm at 6 months. The volume calculated by the cylinder formula decreased from 15.6 cm³ to 11.6 cm³ at 3 months, rising to 12.3 cm³ at 6 months. Similarly, the volume measured by VOCAL dropped from 16.0 cm³ to 11.8 cm³ at 3 months and increased to 13.1 cm³ at 6 months. The volume of excised tissue influences cervical length, whereas parity affects volume regeneration. Ultrasonography methods for assessing cervical volume showed high concordance.</p><p><strong>Conclusion: </strong>There is a regenerative process of the cervix after LLETZ, complete in terms of length and partial in volume. The volume of the excised tissue and parity influence the regenerative process. Ultrasonographic assessments of cervical volume by two- or three-dimensional methods are comparable.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FIGO best practice guidance for diagnosis and treatment of fibroids.","authors":"Ivo Meinhold-Heerlein, Nikhil Purandare, Ally Murji, Paul Fogarty, Jolly Beyeza, Philippe Descamps","doi":"10.1002/ijgo.70496","DOIUrl":"https://doi.org/10.1002/ijgo.70496","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between umbilical cord concentration of the growth hormone-IGF axis and small for gestational age: A single-center retrospective, observational study.","authors":"Jing Wen, Yan Zhao, Ruoling Xian, Xin Fan","doi":"10.1002/ijgo.70464","DOIUrl":"https://doi.org/10.1002/ijgo.70464","url":null,"abstract":"<p><strong>Objective: </strong>To ascertain the association between small for gestational age (SGA) and growth hormone (GH)-insulin-like growth factor (IGF) system status.</p><p><strong>Methods: </strong>This retrospective, observational single-center study at a tertiary hospital classified 175 newborns into two groups based on their gestational age and birth weight: SGA (n = 87) or appropriate for gestational age (AGA; n = 88). Umbilical cord blood samples were collected during delivery, and GH, IGF-1, and IGF-binding protein-3 (IGFBP-3) levels were measured using electrochemiluminescence immunoassay, liquid chromatography-tandem mass spectrometry, and chemiluminescence immunoassay, respectively.</p><p><strong>Results: </strong>Compared with the AGA group, the GH concentration was significantly higher in the SGA group and the IGF-1 concentration was significantly lower; there was no significant difference in the IGFBP-3 concentration between the two groups. Gestational age, cesarean section, pre-pregnancy maternal body mass index (BMI), weight gain during pregnancy, gestational hypothyroidism, and IGF-1 concentration had a significantly positive association with neonatal birth weight. After adjusting for maternal age, gestational age, fetal sex, mode of delivery, pre-pregnancy BMI, gestational weight gain, gestational hypertension, gestational hypothyroidism, and gestational diabetes, elevated GH levels and decreased IGF-1 levels were both significantly associated with an increased risk of SGA, but there was no association with IGFBP-3.</p><p><strong>Conclusions: </strong>Levels of IGF-1 and GH in the GH-IGF system are associated with SGA. Elevated GH levels and decreased IGF-1 levels both increase the incidence of SGA. Imbalance in the GH-IGF-1 axis may restrict fetal growth and development, thereby increasing the risk of future metabolic diseases.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal characteristics and induction methodologies as predictors of delivery outcomes: A retrospective analysis of inductions of labor.","authors":"Mena Abdalla, Salma Jabak, Aisha Hameed","doi":"10.1002/ijgo.70491","DOIUrl":"https://doi.org/10.1002/ijgo.70491","url":null,"abstract":"<p><strong>Objective: </strong>To analyze maternal characteristics, induction methods, and their association with delivery outcomes in women undergoing induction of labor (IOL).</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 947 women who underwent IOL at the Princess Royal University Hospital during the period from April 2018 to April 2019. Out of 4316 total births during the study period, 947 women underwent IOL and were included in our analysis. Statistical analyses were performed using STATA version 17.0, with appropriate statistical tests including χ² tests, t tests, and logistic regression models.</p><p><strong>Results: </strong>The overall vaginal delivery rate was 71.7% (n = 679) (51.4% (n = 487) spontaneous, 20.3% (n = 192) instrumental), with 28.3% (n = 268) requiring cesarean section. Nulliparity was significantly associated with higher cesarean rates compared with multiparity (39.1% (n = 101/259) versus 24.3% (n = 167/688), P < 0.001; odds ratio [OR] 2.01, 95% confidence interval [CI] 1.52-2.66). Women with a body mass index (BMI; calculated as weight in kilograms divided by the square of height in meters) of 30 or greater had significantly higher cesarean section rates than those with normal BMI (35.4% (n = 91/257) versus 23.2% (n = 94/406), P < 0.001; OR 1.82, 95% CI 1.34-2.47). The mean time from induction to birth was 28.4 h (range 1.05-71.78 h). Logistic regression analysis identified parity (OR 0.61, 95% CI 0.49-0.76), BMI (OR 1.06, 95% CI 1.03-1.09), and maternal age (OR 1.03, 95% CI 1.01-1.05) as independent predictors of cesarean delivery.</p><p><strong>Conclusion: </strong>Maternal characteristics, particularly parity and BMI, significantly influence delivery outcomes following IOL. Understanding these factors can help optimize patient selection, counseling, and management strategies for IOL. Although statistically significant associations were identified, the clinical significance of some factors requires careful interpretation in individual patient counseling.</p><p><strong>Registration number: </strong>Clinical Audit Committee Registration Number: 615/23052025.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genital herpes management in pregnancy: Knowledge and practices of healthcare providers.","authors":"Nir Meller, Itzchak Levy, Yoav Yinon, Riad Kassem, Micha Baum","doi":"10.1002/ijgo.70480","DOIUrl":"https://doi.org/10.1002/ijgo.70480","url":null,"abstract":"<p><strong>Objective: </strong>To assess the knowledge and practices of Israeli healthcare providers in managing genital herpes and evaluate the performance of large language models (LLMs) in addressing key clinical questions.</p><p><strong>Study design: </strong>An anonymous survey comprising 24 questions assessing genital herpes management and guideline familiarity was distributed to healthcare providers (obstetricians and gynecologists (OB-GYNs), dermatologists, infectious disease specialists, and family doctors). Further, four LLM tools were tested on the main questions.</p><p><strong>Results: </strong>Overall, 122 physicians participated, with OB-GYNs showing the highest familiarity with guidelines; however, only 22.9% of respondents were fully familiar with local guidelines. Significant knowledge gaps in transmission risks and preventive treatments were identified. LLM tools demonstrated strong performance, often surpassing physicians in accuracy, but exhibited limitations in interpreting certain guideline aspects.</p><p><strong>Conclusions: </strong>Israeli healthcare providers show critical knowledge gaps, underscoring the need for enhanced education and guidelines. Further, LLMs show promise as supplementary tools for improving guideline adherence.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of serum calponin-2 in the differential diagnosis of pregnancy of unknown location: A prospective analysis.","authors":"Muhammed Ahsen Ogrenci, Gulten Ozgen, Nergis Kender Erturk, Burcu Dincgez","doi":"10.1002/ijgo.70477","DOIUrl":"https://doi.org/10.1002/ijgo.70477","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates the diagnostic utility of serum calponin-2 (CNN-2) levels in the differential diagnosis and risk stratification of pregnancy of unknown location (PUL).</p><p><strong>Methods: </strong>This prospective longitudinal study included 116 patients diagnosed with PUL between September 2022 and September 2023 at a tertiary hospital. Patients were classified according to final diagnosis into ectopic pregnancy (n = 26), failed PUL (n = 36), and intrauterine pregnancy (n = 54) groups and risk stratified into high-risk and low-risk categories using the M6 model. Serum CNN-2 levels were measured at admission. The diagnostic performance of CNN-2 was assessed using receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>Calponin-2 levels were significantly higher in ectopic pregnancy cases compared to failed PUL and intrauterine pregnancies (P = 0.019 and P < 0.001, respectively) and higher in failed PUL compared to intrauterine pregnancies (P < 0.001). No difference was observed between viable and non-viable intrauterine pregnancies (P = 0.187). CNN-2 distinguished high-risk from low-risk PUL with 88.5% sensitivity and 78.9% specificity at a cut-off of 0.17 ng/mL (AUC = 0.893, P < 0.001). A CNN-2 level of ≤0.15 ng/mL identified intrauterine pregnancies with 90.7% sensitivity and 79% specificity (AUC = 0.904, P < 0.001).</p><p><strong>Conclusion: </strong>Serum CNN-2 is a promising biomarker for early risk stratification and differential diagnosis in PUL. Its measurement might aid in timely identification of ectopic pregnancies and reduce reliance on serial β-hCG testing. Further multicenter studies are needed to validate its clinical applicability.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of sleep problems during pregnancy, coping strategies, and ınfluencing factors: A cross-sectional study.","authors":"Nermin Altunbaş","doi":"10.1002/ijgo.70483","DOIUrl":"https://doi.org/10.1002/ijgo.70483","url":null,"abstract":"<p><strong>Objective: </strong>The present study aimed to identify sleep problems during pregnancy, evaluate coping strategies, and examine the influence of individual factors on these issues.</p><p><strong>Methods: </strong>This prospective, descriptive and cross-sectional study was conducted between July 1, 2024, and February 28, 2025, at the Obstetrics and Gynecology Outpatient Clinic of Sivas Numune Hospital with a sample of 576 pregnant women. Data were collected through face-to-face interviews using the personal ınformation form, the pregnancy sleep problems ıdentification scale, and the coping strategies for sleep problems during pregnancy scale. Data analysis was performed using SPSS 23.0, employing descriptive statistics and multiple linear regression analysis.</p><p><strong>Results: </strong>The participants had a mean age of 28.63 ± 5.15 years and a mean gestational age of 26.38 ± 9.37 weeks. The average sleep problem score was 61.00 ± 10.52, while the mean coping strategy score was 54.48 ± 7.03. The most frequently reported sleep issues were related to physical symptoms and disrupted sleep patterns. The most commonly used coping strategy was \"establishing sleep habits.\" According to the regression analysis, employment status, income level, number of pregnancies, smoking status, caffeine consumption, use of a light source while sleeping, difficulty sleeping with a different bed or pillow, and preferred room temperature had a significant effect on both sleep problems during pregnancy and the coping strategies used (P < 0.001; f1² = 1.348, f2² = 0.724). The model explained 57.4% of the variance in sleep problems and 42.0% in coping strategies.</p><p><strong>Conclusion: </strong>Sleep problems are prevalent during pregnancy and are significantly associated with personal and lifestyle factors. It is recommended that nurses regularly assess sleep quality in pregnant women and provide individualized interventions to promote better sleep health.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trans-broad-ligament abdominal cerclage versus blind needle-piercing abdominal cerclage during pregnancy: A comparison of surgical outcomes.","authors":"Qiannan Yang, Daniel Y Lovell, Joseph Nassif, Lubna Chohan, Jugnu Biba Nijjar, Nurul Farhanah Binte Abdul Latif, Zhenkun Guan, Xiaoming Guan","doi":"10.1002/ijgo.70475","DOIUrl":"https://doi.org/10.1002/ijgo.70475","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FIGO call to action: Multisectoral approach to postpartum hemorrhage","authors":"Diana Ramasauskaite,&nbsp;Dietmar Schlembach,&nbsp;Akaninyene E. Ubom,&nbsp;Albaro J. Nieto-Calvache,&nbsp;Cherrie Evans,&nbsp;Ahmet M. Gülmezoglu,&nbsp;Jolly Beyeza-Kashesya,&nbsp;Bo Jacobsson,&nbsp;Alison Wright,&nbsp;For the FIGO Committee on Childbirth and PPH","doi":"10.1002/ijgo.70449","DOIUrl":"10.1002/ijgo.70449","url":null,"abstract":"<p>Maternal mortality from postpartum hemorrhage is not only a medical issue but a social one as well, dependent mainly on persistent inequities in global health and socioeconomic development. Research, evidence-based clinical practice, and advocacy are the cornerstones of strategy in decreasing maternal mortality and near-miss cases of postpartum hemorrhage. Multisectoral coordination is crucial in optimizing the usage of resources by avoiding duplication of inputs and activities.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":"171 1","pages":"45-53"},"PeriodicalIF":2.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.70449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}