International Journal of Gynecology & Obstetrics最新文献

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Laparoscopic excision of a large 25 cm adnexal mass with ovarian preservation while minimizing spillage. 腹腔镜切除 25 厘米大的附件肿块,保留卵巢的同时尽量减少溢液。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-16 DOI: 10.1002/ijgo.15862
Saboohi Tariq, Parijot Kumar, Fadi-Tamas Salameh
{"title":"Laparoscopic excision of a large 25 cm adnexal mass with ovarian preservation while minimizing spillage.","authors":"Saboohi Tariq, Parijot Kumar, Fadi-Tamas Salameh","doi":"10.1002/ijgo.15862","DOIUrl":"10.1002/ijgo.15862","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"830-832"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing risk factors and neonatal outcomes in women with intrahepatic cholestasis of pregnancy between assisted reproductive technology and spontaneous conception. 比较辅助生殖技术和自然受孕的妊娠肝内胆汁淤积症妇女的风险因素和新生儿结局。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-22 DOI: 10.1002/ijgo.15878
Jingwei Yang, Jing Gao, Danni Zhou, Hong Ye, Guoning Huang, Xuemei Lian, Xiaodong Zhang
{"title":"Comparing risk factors and neonatal outcomes in women with intrahepatic cholestasis of pregnancy between assisted reproductive technology and spontaneous conception.","authors":"Jingwei Yang, Jing Gao, Danni Zhou, Hong Ye, Guoning Huang, Xuemei Lian, Xiaodong Zhang","doi":"10.1002/ijgo.15878","DOIUrl":"10.1002/ijgo.15878","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to investigate the incidence of intrahepatic cholestasis of pregnancy (ICP) as well as neonatal outcomes between conception via in vitro fertilization (IVF) compared with spontaneous conception (SC) and screen the risk factors of ICP in IVF.</p><p><strong>Methods: </strong>This retrospective cohort study included 4467 puerperae who conceived via IVF, and 28 336 puerperae who conceived spontaneously and linked the information from neonates. The general linear model (GLM), multivariate logistic regression analysis, a forest plot, and nomogram were used to assess impact factors and risk prediction.</p><p><strong>Results: </strong>Logistic analysis adjusted for confounders revealed significant differences in the ICP rate of singleton delivery (4.24% vs 3.41%, adjusted OR [aOR] = 1.26; 95% confidence interval [CI] 1.03-1.53, P = 0.025) and in groups with total bile acids (TBA) ≥40 and <100 μmol/L (14.77% vs 10.39%, aOR = 1.31; 95% CI: 1.06-1.63, P = 0.023) between IVF and SC. When we divided newborns into singleton and twins delivery, the GLM revealed a higher rate with Apgar score <7 (13.44% vs 3.87%, aOR = 3.85; 95% CI: 2.07-7.17, P < 0.001) and fetal distress for IVF in comparison with SC (19.32% vs 5.55%, OR = 3.48; 95% CI: 2.39-6.95, P < 0.001) in the singleton group. In multivariate logistic regression analysis, body mass index (BMI) (aOR = 1.29; P = 0.031), number of embryo transfers (ET) (single ET vs double ET, aOR = 2.82; P < 0.001), E<sub>2</sub> level on the ET day (aOR = 2.79; P = 0.011), fresh ET which compared with frozen ET (FET) (aOR = 1.45; P = 0.014), embryo stage (cleavage embryo vs blastocyst, aOR = 1.75; P = 0.009) and severe ovarian hyperstimulation syndrome (OHSS) which compared with non-OHSS (aOR = 3.73; P = 0.006) were independent predictors of ICP. These predictive factors in the logistic regression model were integrated into the nomogram (C-index = 0.735; 95% CI: 0.702-0.764); for each patient, higher total points indicated a higher risk of ICP.</p><p><strong>Conclusion: </strong>We observed that the ICP rate of singleton delivery was higher in IVF than in SC. In ICP patients, there were higher rates of neonatal Apgar score <7 and fetal distress in IVF than SC and found the predictors of ICP in IVF.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"663-672"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of respectful maternal care training of health care providers on satisfaction with birth experience in mothers undergoing normal vaginal birth: A prospective interventional study. 医护人员尊重产妇护理培训对顺产母亲分娩体验满意度的影响:前瞻性干预研究。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-22 DOI: 10.1002/ijgo.15875
Meenakshi Singh, Shailley Baruhee, Pikee Saxena
{"title":"Impact of respectful maternal care training of health care providers on satisfaction with birth experience in mothers undergoing normal vaginal birth: A prospective interventional study.","authors":"Meenakshi Singh, Shailley Baruhee, Pikee Saxena","doi":"10.1002/ijgo.15875","DOIUrl":"10.1002/ijgo.15875","url":null,"abstract":"<p><strong>Objective: </strong>To study the impact of respectful maternity care (RMC) training of health care providers on RMC and birth satisfaction in mothers undergoing normal vaginal birth.</p><p><strong>Methods: </strong>A prospective interventional study was performed comparing RMC and birth satisfaction in women undergoing vaginal births before and after RMC training of health care providers from November 2021 to March 2023 in a tertiary care center in India. Person-centered maternity care (PCMC) and birth satisfaction scale-revised (BSSR) scales were used to study women's RMC and birth satisfaction, respectively.</p><p><strong>Results: </strong>A total of 100 women undergoing normal vaginal birth were enrolled in pre- and post-intervention phases. The intervention was done through formal and onsite training of health care providers in RMC. The mean total PCMC scale score in the post-training group demonstrated a remarkable increase to 51.95 ± 6.50, significantly higher than the pre-training mean of 32.82 ± 8.47 (P < 0.0001). The mean ± SD of the BSSR scale total score in the post-training group increased significantly to 27.17 ± 3.67, surpassing the pre-training mean of 21.19 ± 5.48 (P < 0.0001).</p><p><strong>Conclusion: </strong>The study showed significant improvement in RMC and birth satisfaction score in the post-training group thereby emphasizing the importance of RMC training of health care providers in the facility.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"673-679"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superior hypogastric nerve plexus (SHNP) block for pain management after minimally invasive gynecology surgeries: A prospective randomized controlled trial. 用于妇科微创手术后疼痛控制的胃上神经丛(SHNP)阻滞:前瞻性随机对照试验。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-09-23 DOI: 10.1002/ijgo.15926
Neha Agrawal, Pratibha Singh, Manu Goyal, Garima Yadav, Shashank Shekhar
{"title":"Superior hypogastric nerve plexus (SHNP) block for pain management after minimally invasive gynecology surgeries: A prospective randomized controlled trial.","authors":"Neha Agrawal, Pratibha Singh, Manu Goyal, Garima Yadav, Shashank Shekhar","doi":"10.1002/ijgo.15926","DOIUrl":"10.1002/ijgo.15926","url":null,"abstract":"<p><strong>Objectives: </strong>Our study aimed to evaluate the effect of superior hypogastric nerve plexus (SHNP) block in postoperative pain management in the first 24 h after minimally invasive gynecological (MIG) surgeries.</p><p><strong>Methods: </strong>We conducted a double-blinded, randomized controlled trial in the Department of Obstetrics and Gynecology at a tertiary care centre from May 1, 2023 to September 30, 2023 in women undergoing major MIG surgeries. At the completion of the surgery, women were randomized to the intervention group who received SHNP block with ropivacaine 10 mL (0.75%) before port removal, whereas no intervention was taken in the control group. The extubation time was noted, and the pain score was assessed after 1, 2, 6, 12, and 24 h of extubation in the postoperative period using the visual analog scale (VAS). Statistical analysis was done, with a significance level of 0.05, to test the differences between the two groups.</p><p><strong>Results: </strong>A total of 64 patients were randomly allocated to intervention and control groups. The median pain score was lower at 1 and 2 h post-extubation and comparable between the two groups at 6, 12, and 24 h. The surrogate markers that is need for additional analgesia and duration of stay did not differ significantly in the two groups, with P-values of 0.08 and 0.943, respectively.</p><p><strong>Conclusion: </strong>Although the SHNP group experienced considerably lower immediate postoperative pain levels in the initial hours following extubation, the impact of this benefit remains uncertain in the longer postoperative period. The effectiveness of this modality for pain control needs further study, particularly at later postoperative hours.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"605-612"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fungibility, accessibility and clinical utility of remote electronic fetal monitoring in improving maternal emotional status compared with traditional method: A multicenter prospective cohort analysis. 与传统方法相比,远程电子胎儿监护在改善产妇情绪状态方面的可行性、可及性和临床实用性:多中心前瞻性队列分析。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-09-26 DOI: 10.1002/ijgo.15917
Yu Pan, Zi Chen, Lujiao Chen, Lingli Ning, Huimin Wan, Ting Chen, Haihong Zhang, Ying Jiang, Qiong Luo
{"title":"Fungibility, accessibility and clinical utility of remote electronic fetal monitoring in improving maternal emotional status compared with traditional method: A multicenter prospective cohort analysis.","authors":"Yu Pan, Zi Chen, Lujiao Chen, Lingli Ning, Huimin Wan, Ting Chen, Haihong Zhang, Ying Jiang, Qiong Luo","doi":"10.1002/ijgo.15917","DOIUrl":"10.1002/ijgo.15917","url":null,"abstract":"<p><strong>Objective: </strong>Supported by remote signal processing techniques and wireless communication technology, remote electronic fetal monitoring (REFM) has emerged as a promising alternative to traditional electronic fetal monitoring (TEFM) in clinical practice. The aim of this study was to evaluate the comparability, accessibility, and clinical utility of REFM in contrast to TEFM.</p><p><strong>Methods: </strong>This was a multicenter prospective cohort study. A cohort of 2900 pregnant women were enrolled from three medical centers between June 1, 2021 and June 31, 2022. Among them, 800 utilized REFM, with 760 of them completing the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) assessments using the devices for 1 month. The control group comprised 2100 pregnant women who did not use REFM. Additionally, 80 pregnant women concurrently employed both REFM and TEFM, and their respective curve coincidence rates were determined through curve fitting. Primary outcomes encompassed pregnancy outcomes in both groups, average curve coincidence rates between REFM and TEFM, as well as SDS and SAS scores.</p><p><strong>Results: </strong>Among the 760 pregnant women who completed SAS and SDS assessments, their average SAS scores before and after 1 month of REFM usage were 43.09 ± 8.04 and 41.58 ± 6.59, respectively. Concurrently, the average SDS scores before and after 1 month of REFM usage were 45.45 ± 9.60 and 44.80 ± 9.17, respectively. A statistically significant decrease was observed in SAS scores (P = 0.005), whereas no significant difference was noted in SDS scores (P = 0.340). Furthermore, a statistically significant difference in the rate of adverse pregnancy outcomes (neonatal asphyxia) emerged between the two groups, those who employed REFM and those who did not (P = 0.021). In the subset of 80 pregnant women employing both REFM and TEFM, all 80 results showed precise congruence between the two methods. The average coincidence rate was determined to be 79.45% ± 12.64%.</p><p><strong>Conclusion: </strong>REFM contributes to improved pregnancy outcomes and exhibits a high level of concordance with TEFM, thereby accurately reflecting the quality of fetal heart monitoring. Additionally, REFM effectively mitigates pregnant women's anxiety. Thus, REFM demonstrates comparability, accessibility, and clinical utility.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"822-829"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic sacrocolpopexy with concurrent hysterectomy or uterine preservation: A metanalysis and systematic review. 腹腔镜骶骨整形术同时进行子宫切除术或保留子宫:荟萃分析和系统综述。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-09-26 DOI: 10.1002/ijgo.15891
Veronica Tius, Martina Arcieri, Cristina Taliento, Giulia Pellecchia, Giampiero Capobianco, Tommaso Simoncini, Giovanni Panico, Daniela Caramazza, Giuseppe Campagna, Lorenza Driul, Giovanni Scambia, Alfredo Ercoli, Stefano Restaino, Giuseppe Vizzielli
{"title":"Laparoscopic sacrocolpopexy with concurrent hysterectomy or uterine preservation: A metanalysis and systematic review.","authors":"Veronica Tius, Martina Arcieri, Cristina Taliento, Giulia Pellecchia, Giampiero Capobianco, Tommaso Simoncini, Giovanni Panico, Daniela Caramazza, Giuseppe Campagna, Lorenza Driul, Giovanni Scambia, Alfredo Ercoli, Stefano Restaino, Giuseppe Vizzielli","doi":"10.1002/ijgo.15891","DOIUrl":"10.1002/ijgo.15891","url":null,"abstract":"<p><strong>Background: </strong>Literature is lacking strong evidence about comparisons of efficacy and quality of life-related outcomes between laparoscopic total and/or supracervical hysterectomy (LTH/LSCH) with laparoscopic sacrocolpopexy (LSC) and minimally invasive sacrohysteropexy (LSH).</p><p><strong>Objective: </strong>To summarize and compare available data on this topic providing a useful clinical tool in the treatment decision process.</p><p><strong>Search strategy: </strong>We performed a systematic research of PubMed (MEDLINE), Web of Science, and Gooogle Scholar.</p><p><strong>Selection criteria: </strong>We included studies that compared at least one efficacy outcome (objective or subjective outcome) between LTH/LSCH with LSC and LSH. Data on surgery-related morbidities were also extracted where available.</p><p><strong>Data collection and analysis: </strong>A random-effect meta-analysis was conducted reporting pooled mean differences and odds ratios (OR) between groups using Review Manager V.7.9.0.</p><p><strong>Main results: </strong>We included a total of nine observational studies. LTH/LSCH with LSH was associated with a significantly higher objective success (apical compartment OR 7.95; 95% confidence interval [CI] 2.23-28.33; I<sup>2</sup> = 0%; P = 0.001; anterior compartment OR 2.23; 95% CI 1.26-4.30; I<sup>2</sup> = 12%; P = 0.007) and subjective success (OR 3.19; 95% CI 1.42-7.17; I<sup>2</sup> = 39%; P = 0.005). No differences were found regarding intraoperative and postoperative complications, sexual dysfunction, and stress urinary incontinence rate after surgery. Hysteropexy showed shorter operative time and shorter hospital length with a pool mean difference of 27.37 min (95% CI 18.04-32.71; I<sup>2</sup> = 0%; P < 0.001) and 0.7 days (95% CI 0.24-1.17; I<sup>2</sup> = 75%; P = 0.003), respectively. Concurrent hysterectomy was not associated with a higher rate of mesh-related complications (P = 0.53). No major differences were found regarding recurrence and reoperation rate (P = 0.10 and P = 0.93, respectively).</p><p><strong>Conclusions: </strong>LTH/LSCH with LSC has better objective and subjective outcomes in pelvic organ prolapse surgery than LSH alone, especially for apical and anterior compartments, and is not associated with higher postoperative sexual dysfunction and mesh-related complications. Adequate preoperative counseling is highly recommended in patients who desire uterine preservation.</p><p><strong>Prospero registration number: </strong>CRD42024537270.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"456-471"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Birth companionship: The effect of introducing Plan-Do-Study-Act (PDSA) intervention on improving quality of care: An implementation study. 分娩陪伴:引入 "计划-实施-研究-行动"(PDSA)干预措施对提高护理质量的影响:一项实施研究。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-12 DOI: 10.1002/ijgo.15863
Kidist Lemma, Delayehu Bekele, Lemi Belay Tolu, Felagot Tadesse, Tsinat Kifle, Abraham Fessehaye Sium
{"title":"Birth companionship: The effect of introducing Plan-Do-Study-Act (PDSA) intervention on improving quality of care: An implementation study.","authors":"Kidist Lemma, Delayehu Bekele, Lemi Belay Tolu, Felagot Tadesse, Tsinat Kifle, Abraham Fessehaye Sium","doi":"10.1002/ijgo.15863","DOIUrl":"10.1002/ijgo.15863","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"842-844"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De novo urethral hypermobility at 6 months after first delivery as a risk factor for stress urinary incontinence 12 years postpartum. 首次分娩后 6 个月时尿道活动过度是产后 12 年出现压力性尿失禁的风险因素。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-19 DOI: 10.1002/ijgo.15864
Miren Arrue Gabilondo, Maria J Belar, Irene Diez-Itza
{"title":"De novo urethral hypermobility at 6 months after first delivery as a risk factor for stress urinary incontinence 12 years postpartum.","authors":"Miren Arrue Gabilondo, Maria J Belar, Irene Diez-Itza","doi":"10.1002/ijgo.15864","DOIUrl":"10.1002/ijgo.15864","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to analyze the association between de novo urethral hypermobility 6 months postpartum and stress urinary incontinence (SUI) symptoms at 6 months and 12 years after first delivery. Risk factors associated with the development of postnatal urethral hypermobility were also examined.</p><p><strong>Methods: </strong>A longitudinal cohort study was conducted on primigravid women, after excluding those with UI before pregnancy and/or urethral hypermobility (rotational angle ≥30°) at term. At 6 months postpartum, SUI was assessed based on symptoms and introital ultrasound performed to measure rotational angle (difference between urethro-pelvic angle at rest and at maximum Valsalva). Twelve years after delivery, women were sent a questionnaire including SUI assessment and questions on parity, current age, and body mass index. Continuous variables were compared using student's t-test and qualitative variables using chi-squared tests. A logistic regression model was constructed including variables that reached statistical significance (P < 0.05) in the univariate analysis.</p><p><strong>Results: </strong>Of the 314 women who completed the 6-month follow-up, 265 (84.4%) were successfully contacted and completed the questionnaire at 12 years and these formed the study group. In 127 women (47.9%), de novo urethral hypermobility had developed by 6 months postpartum. There was no association between urethral hypermobility and SUI symptoms 6 months postpartum (OR: 1.17; 95% CI: 0.59-2.33). Twelve years after delivery, however, SUI was reported by 110 women overall (41.5%) and nearly half of the women who developed postnatal urethral hypermobility (61/127, 48.0%).</p><p><strong>Conclusion: </strong>De novo urethral hypermobility 6 months postpartum constitutes a risk factor for SUI 12 years later.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"634-639"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the diagnostic potential of gelsolin in gestational diabetes mellitus: A case-control study. 评估凝胶酚在妊娠糖尿病中的诊断潜力:病例对照研究
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-21 DOI: 10.1002/ijgo.15872
Betül Tokgöz Çakır, Gizem Aktemur, Gülşan Karabay, Zeynep Şeyhanlı, Serap Topkara Sucu, Ömer Osman Eroğlu, Seval Yılmaz Ergani, Can Tekin İskender
{"title":"Evaluating the diagnostic potential of gelsolin in gestational diabetes mellitus: A case-control study.","authors":"Betül Tokgöz Çakır, Gizem Aktemur, Gülşan Karabay, Zeynep Şeyhanlı, Serap Topkara Sucu, Ömer Osman Eroğlu, Seval Yılmaz Ergani, Can Tekin İskender","doi":"10.1002/ijgo.15872","DOIUrl":"10.1002/ijgo.15872","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the association between gestational diabetes mellitus (GDM) and blood levels of gelsolin (an inflammation-related protein thought to be reduced in type 2 diabetes mellitus) and to determine its role in potential diagnosis and neonatal outcomes.</p><p><strong>Methods: </strong>This prospective case-control study was conducted at Ankara Etlik City Hospital between November 2023 and February 2024 with 40 pregnant women with GDM and 40 normoglycemic women. Pregnant women aged 18-40 years who were in their 24th to 28th week of pregnancy and had no known chronic disease were included in the present study and it was investigated as to whether there was a significant difference between the two groups in terms of gelsolin levels and neonatal outcome.</p><p><strong>Results: </strong>Gelsolin level was statistically significantly lower in the GDM group than in the control group (P = 0.004). In patients with fasting blood glucose <96 mg/dL, maternal serum gelsolin levels were associated with GDM, with a cut-off of 15.38 or less, showing a sensitivity of 73%, a specificity of 67%, and an area under the curve (AUC) of 0.703 (95% confidence interval [CI] 0.576-0.810, P = 0.002). There was no difference between groups in terms of adverse obstetric outcomes, but gelsolin levels were associated with composite neonatal adverse outcome (macrosomia, Apgar score at 5 min less than 7, preterm birth, need for neonatal intensive care), with a cut-off value of 16.66 or less showing a sensitivity of 84.6%, specificity of 40.7% and AUC of 0.644 (95% CI 0.529-0.748, P = 0.031).</p><p><strong>Conclusion: </strong>Gelsolin could potentially serve as a promising biomarker for the diagnosis of GDM.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"656-662"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analyzing the performance of ChatGPT in answering inquiries about cervical cancer. 分析 ChatGPT 在回答宫颈癌相关咨询时的性能。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-02-01 Epub Date: 2024-08-16 DOI: 10.1002/ijgo.15861
Engin Yurtcu, Seyfettin Ozvural, Betul Keyif
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