Luís Henrique Leão, Camila Ayume Amano Cavalari, Luiz Francisco Baccaro
{"title":"Ectopic and molar pregnancies in Brazil: A secondary analysis of the WHO multi-country survey on abortion.","authors":"Luís Henrique Leão, Camila Ayume Amano Cavalari, Luiz Francisco Baccaro","doi":"10.1002/ijgo.70142","DOIUrl":"https://doi.org/10.1002/ijgo.70142","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethical and professional obligations of gynecologists and obstetricians in response to reproductive injustice.","authors":"Leonel Briozzo, Frank A Chervenak","doi":"10.1002/ijgo.70075","DOIUrl":"https://doi.org/10.1002/ijgo.70075","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shefaly Shorey, John Chee Meng Wong, Darius Lim, Crystal Min Siu Chua, Jia Ying Teng, Lina Hsiu Kim Lim
{"title":"Music-based interventions and maternal mental health in the postpartum period: A mixed-studies systematic review.","authors":"Shefaly Shorey, John Chee Meng Wong, Darius Lim, Crystal Min Siu Chua, Jia Ying Teng, Lina Hsiu Kim Lim","doi":"10.1002/ijgo.70133","DOIUrl":"https://doi.org/10.1002/ijgo.70133","url":null,"abstract":"<p><strong>Background: </strong>The transition to motherhood can be stressful. Music-based intervention can help alleviate stress. However, it is underexplored in this field.</p><p><strong>Objective: </strong>We aimed to consolidate and synthesize findings on the available evidence of music-based interventions and maternal mental health among women with healthy term infants in the postpartum period.</p><p><strong>Search strategy: </strong>This is a mixed-studies systematic review. The search strategy included PubMed, EMBASE, CINAHL, PsycINFO, Cochrane Library, Scopus, Google Scholar, and ProQuest Dissertations from inception to April 2022.</p><p><strong>Selection criteria: </strong>Women with healthy-term infants were included. Phenomena of interest include the experiences of music-based intervention that can be classified into two categories: Active intervention (e.g., creating music, playing an instrument, singing, or musical improvisation), or receptive intervention (e.g., listening to music).</p><p><strong>Data collection and analysis: </strong>Thematic synthesis was conducted. Studies were appraised using the mixed method appraisal tool.</p><p><strong>Main results: </strong>Eleven articles were included. Thematic synthesis identified an overarching theme as \"Music-a lifeline to better maternal mental health.\" This was pillared by three themes: (1) Psycho-social impact of music-based interventions, (2) influences of music on mother-infant relationships, and (3) the way forward for music-based interventions. Music-based interventions have mixed influences on symptoms of depression, stress, and anxiety. However, they can alleviate maternal mood, increase the sense of accomplishment, and strengthen mother-infant attachment. This is especially so for group-based and active music-making interventions. Future studies should include the theoretical rationale for choosing the type and mode of music-based interventions. Future research with standardized intervention, population, outcome measures, mode, and place of intervention delivery is needed to ascertain the effects of music-based interventions.</p><p><strong>Conclusions: </strong>Overall, music-based intervention can be an accessible and convenient way to strengthen mother-infant bonding, maternal mood, and sense of accomplishment among women with healthy-term infants.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uterus didelphys bicollis bicolpos-a case report.","authors":"Felix Nyagaka, Felix Oindi","doi":"10.1002/ijgo.70140","DOIUrl":"https://doi.org/10.1002/ijgo.70140","url":null,"abstract":"<p><p>Uterus didelphys refers to a congenital uterine anomaly that occurs due to failed fusion of the paired Müllerian ducts. It is characterized by two separate non-communicating uterine horns each with its cervix and fallopian tube. Duplication may be limited to the uterus, cervix or also involve the vagina. Here, we present a case of a 27-year-old primigravida incidentally diagnosed during pregnancy, followed up with cervical cerclage at 13 weeks due to a short cervix and had preterm delivery via cesarean section at 35 weeks. She had a successful pregnancy outcome and an uneventful postnatal course. Uterus didelphys is associated with better reproductive outcomes compared to other anomalies. However, patients are at risk of fetal malpresentation, preterm labor and cesarean section. Patients therefore need to be counseled on the clinical implications for shared decision making regarding their reproductive health.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bengü Nur Barış Akcan, Salim Neşelioğlu, Burak Elmas
{"title":"Response: Measurement of thiol/disulfide homeostasis and ischemic modified albumin levels in patients with uterine leiomyomas.","authors":"Bengü Nur Barış Akcan, Salim Neşelioğlu, Burak Elmas","doi":"10.1002/ijgo.70120","DOIUrl":"https://doi.org/10.1002/ijgo.70120","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical outcomes among Centchroman users across six medical college hospitals in India.","authors":"A G Radhika, Amita Suneja, Rashmi Gupta, Gowri Dorairajan, Pratima Aggarwal, Venkatesh Ashok, Vanita Suri, Rimpi Singla, Smiti Nanda, Meenakshi Chauhan, Vandana Rani, Nalini Arora, Rachna Chaudhary, Abhilasha Gupta, Rajeev Kumar Malhotra, Shalini Singh","doi":"10.1002/ijgo.70107","DOIUrl":"https://doi.org/10.1002/ijgo.70107","url":null,"abstract":"<p><strong>Objective: </strong>To evaluated the effectiveness, safety, acceptability, and continuation rates of ormiloxifene (Centchroman) which is licensed for contraception only in India.</p><p><strong>Methods: </strong>The prospective observational analytical study was conducted across six centers in India from June 2019 to May 2023. A mixed cohort of 3139 women who opted for Centchroman out of 36 625 eligible women were followed up for 24 months.</p><p><strong>Results: </strong>Mean age of participants was 26 ± 4.4 years. Menstrual abnormalities were the most common side effect, at an average of 1.03-1.17 events per woman. Discontinuation rates were highest within the first 3 months (40.9%) due to menstrual disturbances, notably reduced menstrual flow (60% at 18 months), amenorrhea, heavy or irregular bleeding, and spotting. Life table analysis revealed continuation rates of 78.0%, 47.3%, and 32.2% at 6 weeks, 6 months, and 24 months, respectively. Overall satisfaction from 6 weeks to 12 months after initiation was 75.2%. Failure rate ranged from 0.7%-2.1%. Mean endometrial thickness remained stable throughout the study period (6.54 ± 2.49 to 7.80 ± 1.97 mm), with only two women exhibiting thickened endometrium at 6 months, which was confirmed as secretory endometrium via histopathology. No significant changes in blood pressure or biochemical parameters were observed. Challenges in follow-up and biochemical testing arose due to the COVID-19 pandemic.</p><p><strong>Conclusion: </strong>Centchroman appears to be an effective and affordable non-hormonal contraceptive option, particularly for women contraindicated for hormonal methods. However, pre-emptive counseling regarding potential menstrual side effects is crucial.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Bartolomé, Cecilia Villalain, Laura Pilar Castillo, Rocío Bermejo, Ana Bolívar, Alberto Galindo, Álvaro Tejerizo
{"title":"Translation, transcultural adaptation and validation of the genital appearance satisfaction-Spanish (GAS-S) scale.","authors":"Alba Bartolomé, Cecilia Villalain, Laura Pilar Castillo, Rocío Bermejo, Ana Bolívar, Alberto Galindo, Álvaro Tejerizo","doi":"10.1002/ijgo.70111","DOIUrl":"https://doi.org/10.1002/ijgo.70111","url":null,"abstract":"<p><strong>Objective: </strong>To translate, culturally adapt to Spanish women and evaluate the psychometric properties of the genital appearance satisfaction-Spanish (GAS-S) scale.</p><p><strong>Methods: </strong>GAS is an English validated scale designed to describe genital appearance satisfaction. GAS was forward and backward translated, culturally adapted into Spanish and its content evaluated through Delphi consensus, developing the Spanish scale (GAS-S) composed of 11 items. Its psychometric properties were assessed through an online survey among 200 women who attended gynecologic consults. In addition to GAS-S, the survey included sociodemographic data, Rosenberg self-esteem scale (RSES) and female genital self-image scale (FGSIS-S).</p><p><strong>Results: </strong>A total of 41.1% women in our sample referred concern about their genital's self-image and 12.4% had considered undergoing genital cosmetic surgery. GAS-S proved to relate appropriately with the proposed construct. Mild and moderate inverse correlation was found between total GAS-S score and RSES (r = -0.71) and between GAS-S and FGSIS-S (r = -0.32), respectively. Exploratory factor analysis revealed a three-factor solution like the original scale (\"appearance of genitals\", \"impact on sexual function\" and \"impact on daily living\"). The test proved good internal consistency (Cronbach's alpha 0.86), and test-retest reliability (intraclass correlation 0.89, P < 0.001).</p><p><strong>Conclusion: </strong>GAS-S is an adequate tool to assess women's genital self-appearance satisfaction in the Spanish-speaking population and is potentially more useful in those requesting labiaplasty.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Norayr Nver Ghukasyan, Edita Eduard Gharibyan, Andranik Poghos Poghosyan, Milena Manvel Voskanyan, Georgy Grigory Okoev, Harutyun Norayr Mangoyan, Lusine Simon Sahakyan, Heghine Seyran Khachatryan
{"title":"Pregnancy and delivery in the context of hemolytic uremic syndrome: A surrogacy case report.","authors":"Norayr Nver Ghukasyan, Edita Eduard Gharibyan, Andranik Poghos Poghosyan, Milena Manvel Voskanyan, Georgy Grigory Okoev, Harutyun Norayr Mangoyan, Lusine Simon Sahakyan, Heghine Seyran Khachatryan","doi":"10.1002/ijgo.70144","DOIUrl":"https://doi.org/10.1002/ijgo.70144","url":null,"abstract":"<p><p>Pregnancy complicated by hemolytic uremic syndrome (HUS) and its variants presents significant challenges in obstetric care. Thrombotic microangiopathy (TMA), a key feature of HUS, involves microvascular thrombosis that can affect any organ, leading to thrombocytopenia, Coombs-negative hemolytic anemia, and organ dysfunction. The most common forms of thrombotic microangiopathies encountered in pregnant patients include hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, thrombotic thrombocytopenic purpura, HUS and acute fatty liver of pregnancy. TMAs are classified into inherited or acquired primary, secondary, or infection-associated TMAs. Current classifications define primary TMAs as hereditary (mutations in ADAMTS13, MMACHC [cb1c deficiency], or genes encoding complement proteins) or acquired (autoantibodies to ADAMTS13, or autoantibodies to complement Factor H (FH), which is associated with homozygous CFHR3/1 deletion). TMA is associated with various infections, including Shiga toxin-producing Escherichia coli-induced HUS (STEC-HUS) and pneumococcal HUS, as well as other bacterial and viral infections. Secondary TMAs occur in a spectrum of conditions, and in many cases the pathogenic mechanisms are multifactorial or unknown. The classification presented here is not unequivocal: in some secondary TMAs, for example pregnancy-associated TMA or de novo TMA after transplantation, a significant proportion of individuals will have a genetic predisposition to a primary TMA. Atypical HUS is particularly concerning during pregnancy as it results from genetic and acquired mutations in complement regulatory proteins, those involved in the alternative pathway of the immune system. We report the case of an Armenian surrogate mother who developed Escherichia coli-mediated HUS complicated by septicemia, acute kidney injury and clinical features of TMA, including neurological alterations. Despite these severe complications, the patient only began to show improvement after undergoing plasma exchange therapy following a cesarean delivery. This case underscores the critical need for heightened suspicion of HUS during pregnancy when TMA features are present. Prompt diagnosis is essential to ensure timely and effective treatment, as delays can lead to significant maternal and fetal morbidity.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: A Randomized Controlled Trial of Uterine Exteriorization Versus In Situ Repair of The Uterine Incision During Cesarean Delivery.","authors":"","doi":"10.1002/ijgo.70152","DOIUrl":"https://doi.org/10.1002/ijgo.70152","url":null,"abstract":"<p><strong>Retraction: </strong>W. El-Khayat, M. Elsharkawi, and A. Hassan, \"A Randomized Controlled Trial of Uterine Exteriorization Versus In Situ Repair of The Uterine Incision During Cesarean Delivery,\" International Journal of Gynecology & Obstetrics 127, no. 2 (2014): 163-166. https://doi.org/10.1016/j.ijgo.2014.05.004. The above article, published online on 19 June 2014 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Michael Geary; and John Wiley & Sons Ltd. UK. Concerns were raised by a third party regarding the randomized control trial, including the fact that the primary outcome of the study changed from the original study which received ethical approval. There were also changes in sample size and study design, and it was not clear whether these substantial changes received ethical approval. When clarification was requested from the authors, they failed to provide an adequate response to the concerns. As a result, the data and conclusions are considered unreliable, therefore the article must be retracted.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Theme hotspots and knowledge structure of PCOS: Social network analysis and visualization study based on keywords.","authors":"Yanjun Wang, Jinli Ding, Yuguo Min, Yuyin Zhang, Junren Ming, Tailang Yin","doi":"10.1002/ijgo.70108","DOIUrl":"https://doi.org/10.1002/ijgo.70108","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women. Many scholars have explored the basic and clinical research of PCOS. However, there is still a lack of research on knowledge structure, bibliometric analysis, and visualization results in the PCOS field.</p><p><strong>Objective: </strong>The main purpose of our study was to analyze the current research status of PCOS and explore hotspots and weak points through social network analysis (SNA) and visualization study, providing ideas and opinions for follow-up researchers.</p><p><strong>Methods: </strong>Reports on PCOS in the literature published from January 2018 to October 2022 were collected from the Web of Science database. Based on the statistics of keywords, a co-word network was generated and used to calculate network indicators. The current research hotspots and research trends of PCOS were analyzed with descriptive statistics, co-occurrence analysis, and SNA.</p><p><strong>Results: </strong>A total of 9282 unique keywords (total frequency 29 847) were obtained from 5828 papers, and 121 high-frequency keywords were selected with frequencies greater than or equal to 20. Keywords including insulin resistance, hyperandrogenemia, metabolic syndrome, and overweight rank within the top five in the centrality of these keywords. By network calculation, the PCOS SNA network was divided into eight clusters (C1-C8): C1, reproduction; C2, pathogenesis; C3, related diseases; C4, clinical manifestation; C5, hormone regulation; C6, clinical management; C7, new regulatory factors; and C8, gene polymorphism. Clusters 3, 4, and 6 have higher density, and clusters 1, 3, and 4 have higher degree.</p><p><strong>Conclusions: </strong>This study reveals the research hotspots and structure of PCOS in recent years through SNA and visualization techniques. We conclude that PCOS is closely related to female reproduction. Although the pathogenesis of PCOS is still unclear, insulin resistance may be the key research topic. Hormone regulation is critical for PCOS, and PCOS patients require careful clinical management. We need more research on the genetics of the disease and new regulatory mechanisms. Our findings will provide reliable and valid support to researchers, funders, policymakers, and clinicians.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}