International Journal of Gynecology & Obstetrics最新文献

筛选
英文 中文
Temperature and heat-load exposure effects on preterm births: Insights from a population-based study using distributed lag non-linear models. 温度和热负荷暴露对早产的影响:使用分布滞后非线性模型的基于人群的研究的见解。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-06-05 DOI: 10.1002/ijgo.71112
Bernard Barzilay, Ibrahim Abu-Kishk, Haim Bibi, Dan Waisman, Sharon Daniel
{"title":"Temperature and heat-load exposure effects on preterm births: Insights from a population-based study using distributed lag non-linear models.","authors":"Bernard Barzilay, Ibrahim Abu-Kishk, Haim Bibi, Dan Waisman, Sharon Daniel","doi":"10.1002/ijgo.71112","DOIUrl":"10.1002/ijgo.71112","url":null,"abstract":"<p><strong>Objective: </strong>Preterm birth presents a substantial health, psychological, and economic burden worldwide. Environmental factors, including temperature fluctuations, are known to influence the risk of preterm birth. This study aimed to investigate the association between high temperatures and heat load and preterm births.</p><p><strong>Methods: </strong>Using a time-series analysis, we examined data from all births in five Israeli districts between 2010-2016. Meteorological indices were computed for each district. Distributed lag non-linear models (DLNM) incorporating Poisson regression were employed to investigate the associations between these meteorological indices and the daily number of preterm births across various time lags, assessing both short- and long-term associations, adjusting for seasonality, holidays and the general trend.</p><p><strong>Results: </strong>During the study period, 1 216 040 newborns were delivered, of which 89 544 (7.36%) were preterm (<37 weeks) and 11 154 (0.91%) early preterm (<32 weeks). Significant non-linear associations were found between temperature, heat load, and daily preterm births. Acute exposure to a 1°C increase in mean daily temperature 14 days before delivery was associated with a higher risk of preterm birth (relative risk [RR] = 1.015; 95% confidence interval [CI]: 1.010-1.019). Similarly, acute exposure to a 1°C increase in maximal heat load 14 days before delivery was associated with elevated risk (RR = 1.018; 95% CI: 1.011-1.026). Cumulative effects over 14 days were substantial: a 1°C rise in mean daily temperature was linked to a 16% increase in risk (RR = 1.160; 95% CI: 1.145-1.176), while a 1°C increase in maximal heat load was associated with a 14% increase (RR = 1.139; 95% CI: 1.125-1.153). Similar associations were observed for heat load, and for early preterm and very low birth weight births; however, these subgroup analyses were based on fewer events and had wider CIs.</p><p><strong>Conclusion: </strong>High temperatures and heat load increase the risk of preterm birth over both short- and long-terms. In the context of global warming, these findings may warrant consideration of climate-related risks in maternal health planning and to develop preventive strategies against heat-related pregnancy complications.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"930-940"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing Robson's classification to compare Cesarean section rates over time at a public tertiary care hospital in Pakistan: An eye-opener. 实施罗布森的分类比较剖宫产率随时间在巴基斯坦的公立三级护理医院:令人大开眼界。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-05-23 DOI: 10.1002/ijgo.71076
Humaira Bilqis, Saleema Rehman, Lubna Ejaz Kahloon, Humera Noreen, Tallat Farkhanda, Moizza Aziz
{"title":"Implementing Robson's classification to compare Cesarean section rates over time at a public tertiary care hospital in Pakistan: An eye-opener.","authors":"Humaira Bilqis, Saleema Rehman, Lubna Ejaz Kahloon, Humera Noreen, Tallat Farkhanda, Moizza Aziz","doi":"10.1002/ijgo.71076","DOIUrl":"10.1002/ijgo.71076","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to assess changes in cesarean section (CS) rates over 3 years at a public tertiary care hospital using the Robson Ten Group Classification System (RTGCS). The specific objectives were to compare population distribution across Robson groups, evaluate overall, group-specific, absolute and relative CS rates and assess data quality and completeness.</p><p><strong>Methods: </strong>This analytical cross-sectional study was conducted at a public tertiary care hospital in Rawalpindi, Pakistan and spanned over two phases. Phase 1: June 2019 to November 2019 and phase 2: August 2022 to January 2023. For analysis, RTGCS was applied. Robson's report tables (RRTs) of two phases were generated to calculate and compare CS rates. Statistical analysis included the calculation of P values (considering <0.05 as significant) by chi-square and Fisher exact tests, odds ratios (ORs), relative risks (RRs) and 95% confidence intervals (CIs), using established online tools.</p><p><strong>Results: </strong>The total number of women included in study during phase 1 were 5437, and in phase 2 were 3762. Overall CS rate increased from 31.06% (phase 1) to 40.09% (phase 2) (P < 0.001). In both phases, Robson group 3 was the largest (33% and 25.2% in phases 1 and 2, respectively) and group 9 was the smallest (<1%). The highest absolute contribution towards CS rate was made by group 5, followed by groups 10 and 2 in both phases. Combined contribution of groups 5, 10, and 2 was 70.5% in phase 1 and 64.9% in phase 2. Group 9 had the highest group-specific CS rate in both phases (93.7% and 100%). In phase 1, it was followed by groups 5 (80.4%), 6 (78.2%) and 7 (72%), while in phase 2 by groups 6 (89.6%), 5 (85.2%), and 8 (72.2%). In CS rate, a statistically significant increase was noted in Robson groups 1, 3, 5, 6, 8, and 10, while a decline was observed in group 4 only.</p><p><strong>Conclusion: </strong>The overall CS rate significantly increased over time. This rise was mainly due to a shift in the obstetric population in high-risk groups; 6, 8, 9, 10, and group 5. Conversely, the reduced CS rates in groups 2 and 4 suggest improved induction practices. The data quality was satisfactory.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"795-806"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148005302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Journey from domestic violence to self-reliance: A case report from a tertiary care crisis center. 从家庭暴力到自力更生的旅程:来自三级护理危机中心的案例报告。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-06-10 DOI: 10.1002/ijgo.71126
Maimoona Ahmed, Mumtaz Fathima
{"title":"Journey from domestic violence to self-reliance: A case report from a tertiary care crisis center.","authors":"Maimoona Ahmed, Mumtaz Fathima","doi":"10.1002/ijgo.71126","DOIUrl":"10.1002/ijgo.71126","url":null,"abstract":"<p><p>Domestic violence and abuse (DVA) remains a major public health and human rights concern, with profound consequences for women's physical, psychological, and socioeconomic well-being. We report the case of a 32-year-old married woman and mother of two who experienced prolonged domestic violence, including physical, emotional, and economic abuse, compounded by her husband's alcohol dependence. Economic abuse escalated when debt incurred through a self-help group loan, intended to support the family's livelihood, was transferred to the survivor, reinforcing financial dependency and coercive control. Following a severe episode of physical violence that resulted in her displacement from the marital home, she sought support through a hospital-based crisis center established within a tertiary care women's hospital. Through crisis intervention, structured counseling, legal guidance, child welfare support, and employment assistance, the survivor achieved financial independence, secured safe accommodation, and initiated steps toward legal separation. This case highlights the often-overlooked role of economic abuse and debt bondage as mechanisms of control within abusive relationships. It also demonstrates the value of integrated, hospital-based crisis services and intersectoral collaboration in supporting survivors of violence. Strengthening routine identification of DVA within healthcare settings, expanding access to crisis centers, and promoting women's economic empowerment may contribute to improved safety and long-term recovery for survivors.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"1055-1057"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic ultrasound eXAmination: Analysis of fellow surgeons learning curve in minimally invasive gynecologic procedures (LUXA study). 腹腔镜超声检查:同行外科医生在微创妇科手术中的学习曲线分析(LUXA研究)。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-06-10 DOI: 10.1002/ijgo.71130
Maria Teresa Giudice, Francesca Moro, Marianna Ciancia, Consuelo Russo, Diana Giannarelli, Serena Cappuccio, Matteo Loverro, Camilla Fedele, Marco D'Indinosante, Andrea Rosati, Emanuele Perrone, Francesca Ciccarone, Floriana Mascilini, Anna Fagotti, Francesco Fanfani, Antonia C Testa
{"title":"Laparoscopic ultrasound eXAmination: Analysis of fellow surgeons learning curve in minimally invasive gynecologic procedures (LUXA study).","authors":"Maria Teresa Giudice, Francesca Moro, Marianna Ciancia, Consuelo Russo, Diana Giannarelli, Serena Cappuccio, Matteo Loverro, Camilla Fedele, Marco D'Indinosante, Andrea Rosati, Emanuele Perrone, Francesca Ciccarone, Floriana Mascilini, Anna Fagotti, Francesco Fanfani, Antonia C Testa","doi":"10.1002/ijgo.71130","DOIUrl":"10.1002/ijgo.71130","url":null,"abstract":"<p><strong>Objective: </strong>Laparoscopic ultrasound (LUS), performed with an endoscopic ultrasound probe, has shown potential in addressing challenges related to haptic perception and lesion detection in minimally invasive surgery. The aim of the present study was to evaluate the learning curve of gynecologic surgery fellows in achieving competency in LUS image acquisition during minimally invasive procedures.</p><p><strong>Methods: </strong>This prospective single-center study included six gynecologic fellows with limited ultrasound experience who completed a one-day structured training program. Fellows performed laparoscopic ultrasound during elective surgeries for benign conditions and early-stage gynecologic cancers, assessing five anatomical sites. Competency was evaluated using learning curve cumulative summation (LC-CUSUM) analysis based on image quality and examination time. Learning curve time and quality score for each surgeon and anatomical site were measured.</p><p><strong>Results: </strong>A total of 56 patients and examinations were analyzed. All fellows achieved competency within 2-5 procedures, with LC-CUSUM showing rapid and sustained skill acquisition. Ovarian imaging required fewer attempts than myometrial wall and iliac vessel imaging, with the right external iliac vessels being the most challenging. Patient characteristics did not differ among fellows.</p><p><strong>Conclusion: </strong>After targeted training, gynecologic surgery fellows can achieve proficiency in LUS within a short learning curve. These findings support the feasibility of integrating LUS training into gynecologic surgical education and highlight its potential to enhance surgical precision and to reduce surgical overall time.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"969-976"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes of placenta accreta spectrum in a Tunisian referral maternity unit: A retrospective review. 临床结果的胎盘增生频谱在突尼斯转诊产科单位:回顾性审查。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-05-22 DOI: 10.1002/ijgo.71098
Hannachi Mohammed Amine, Samaali Khaoula, Zangar Salim, Somri Bilel, Hkiri Takwa, Ben Amor Feriel, Ben Aziza Rim, Ben Marzouk Sofiane, Kacem Samia, Malek Monia, Neji Khaled
{"title":"Clinical outcomes of placenta accreta spectrum in a Tunisian referral maternity unit: A retrospective review.","authors":"Hannachi Mohammed Amine, Samaali Khaoula, Zangar Salim, Somri Bilel, Hkiri Takwa, Ben Amor Feriel, Ben Aziza Rim, Ben Marzouk Sofiane, Kacem Samia, Malek Monia, Neji Khaled","doi":"10.1002/ijgo.71098","DOIUrl":"10.1002/ijgo.71098","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"1045-1047"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147987494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applied surgical anatomical approach to pudendal nerve: Step-by-step key neurovascular structures for pelvic nerve surgery. 阴部神经的应用外科解剖入路:骨盆神经手术的一步一步关键神经血管结构。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-05-09 DOI: 10.1002/ijgo.71065
Merve Didem Eşkin Tanrıverdi, Ayhan Cömert, Zekiye Gözde Kara, Hasan Onur Topçu, Halil İbrahim Açar
{"title":"Applied surgical anatomical approach to pudendal nerve: Step-by-step key neurovascular structures for pelvic nerve surgery.","authors":"Merve Didem Eşkin Tanrıverdi, Ayhan Cömert, Zekiye Gözde Kara, Hasan Onur Topçu, Halil İbrahim Açar","doi":"10.1002/ijgo.71065","DOIUrl":"10.1002/ijgo.71065","url":null,"abstract":"<p><strong>Objective: </strong>To define and demonstrate a step-by-step surgical anatomical approach to pudendal nerve dissection using female cadavers, focusing on the identification of safe roadmap and key neurovascular structures to optimize pelvic nerve surgery.</p><p><strong>Methods: </strong>A descriptive anatomical study was conducted on 60 hemipelvises from 30 female cadavers. Dissections were performed in three stages comprising nine procedural steps to expose the pudendal nerve and related pelvic nerves. Key neurovascular landmarks were documented using video recordings.</p><p><strong>Results: </strong>The dissection was organized into three stages: (1) exposure of the genitofemoral nerve and obturator fossa and its contents, (2) identification of the lumbosacral trunk and sciatic nerve, and greater sciatic notch (3) visualization of the pudendal nerve beneath the sacrospinous ligament. Variations in pudendal nerve branching and anatomical relationships with adjacent structures, including the sacrospinous ligament and ischial spine, were documented. This stepwise approach provided clear surgical landmarks to minimize the risk of nerve injury during pelvic surgery.</p><p><strong>Conclusion: </strong>This cadaveric study provides a detailed, practical roadmap for pudendal nerve dissection, enhancing anatomical understanding of pelvic neurovascular structures. The defined surgical approach in three stages, nine steps, and this comprehensive anatomical understanding can improve surgical precision and supports safer nerve-sparing techniques in complex pelvic surgery including gynecologic pelvic surgical procedures, surgeries for pudendal neuralgia, and deep infiltrating endometriosis.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"715-723"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interrelationships among parenting behaviors, breastfeeding participation, and breastfeeding attitudes of mothers and fathers in the postpartum period: A prospective study. 产后父母教养行为、母乳喂养参与与母乳喂养态度的相互关系:一项前瞻性研究。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-08-20 DOI: 10.1002/ijgo.71284
Büşra Cengiz, Ekin Dila Topaloğlu Ören
{"title":"Interrelationships among parenting behaviors, breastfeeding participation, and breastfeeding attitudes of mothers and fathers in the postpartum period: A prospective study.","authors":"Büşra Cengiz, Ekin Dila Topaloğlu Ören","doi":"10.1002/ijgo.71284","DOIUrl":"10.1002/ijgo.71284","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to examine the interrelationships among parenting behaviors, breastfeeding participation, and breastfeeding attitudes of mothers and fathers in the postpartum period and to identify the sociodemographic and clinical factors associated with these variables.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study was a descriptive, analytical, and prospective study. The study was conducted between March 2023 and October 2023 with a total of 400 parents, comprising 200 mothers and 200 fathers, who were admitted to the postnatal clinics of a university-affiliated training and research hospital in İzmir for delivery purposes. Data were collected using the \"Individual Identification Form-Mother,\" \"Individual Identification Form-Father,\" \"Postpartum Parenting Behavior Scale (PPBS)\" (The same scale was abbreviated as M-PPBS for mothers and F-PPBS for fathers), \"Mother Breastfeeding Attitude Assessment Scale (M-BASS),\" and \"Father's Breastfeeding Attitude (F-BA) and Participation in Breastfeeding (F-PB).\" In the study, the t-test and one-way analysis of variance were used to compare the descriptive information and scores of the scales. Spearman correlation analysis was used to determine the relationship between the scores of scales. The paired sample t-test was used to determine changes in mothers' attitudes toward breastfeeding and fathers' attitudes and participation in breastfeeding over time. Regression analysis was performed to investigate the effect of mothers' and fathers' parenting behaviors, fathers' breastfeeding attitudes, and fathers' participation on mothers' breastfeeding attitudes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The scores of M-PPBS and F-PPBS were 4.52 ± 1.43 and 4.13 ± 1.71, respectively. The M-BAAS scores were 120.18 ± 14.41 at the second follow-up and 119.71 ± 14.58 at the third follow-up (P &gt; 0.05). The F-BA scores were 53.35 ± 5.98 at the second follow-up and 54.04 ± 6.14 at the third follow-up (P &lt; 0.05). The F-PB scores were 53.25 ± 10.08 at the second follow-up and 52.55 ± 10.47 at the third follow-up (P &gt; 0.05). It was determined that some sociodemographic characteristics affected the scores of M-PPBS, F-PPBS, M-BAAS, F-BA, and F-PB (Tables 2 and 4, P &lt; 0.05). It was determined that there was a weakly significant positive correlation between M-PPBS and F-PPBS scores (r = 0.299; P &lt; 0.05). There was a moderate, statistically significant positive correlation between F-BA and F-PB in both the second and third follow-ups (r = 0.314, 0.559; P &lt; 0.05). According to the results of multiple regression analysis, it was found that an increase of 1 unit in the scores of the M-BAAS in the second follow-up increased the scores of the M-BAAS in the third follow-up by 0.7 units (B = 0.689; B = 0.703; P &lt; 0.05, respectively). In the second follow-up, fathers' attitudes toward and participation in breastfeeding predicted mothers' attitudes toward breastfeeding (B = 0.630; B = 0.208; P &lt; 0.05, respectively, Table","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"1030-1042"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paroxetine versus placebo for the management of vasomotor symptoms in surgical menopause: A pilot double-blind randomized clinical trial. 帕罗西汀与安慰剂对手术绝经期血管舒缩症状的治疗:一项试点双盲随机临床试验
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-05-22 DOI: 10.1002/ijgo.71093
Heisell Gabriela Álvarez Castro, Alejandra Paola Romero Huete, Rubí Emelda Bu Urbina, Arnold Reinieri Cambar-González, Ricardo Arturo Gutierrez-Ramirez
{"title":"Paroxetine versus placebo for the management of vasomotor symptoms in surgical menopause: A pilot double-blind randomized clinical trial.","authors":"Heisell Gabriela Álvarez Castro, Alejandra Paola Romero Huete, Rubí Emelda Bu Urbina, Arnold Reinieri Cambar-González, Ricardo Arturo Gutierrez-Ramirez","doi":"10.1002/ijgo.71093","DOIUrl":"10.1002/ijgo.71093","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of low-dose paroxetine (20 mg/day) compared with placebo for managing vasomotor symptoms (VMS) in women with surgical menopause.</p><p><strong>Methods: </strong>This was a pilot randomized, double-blind, placebo-controlled trial conducted at the Instituto Hondureño de Seguridad Social (IHSS), Tegucigalpa, Honduras, from January 30 to July 31, 2025. Women aged <48 years, within 6 months of total hysterectomy with bilateral salpingo-oophorectomy, and experiencing moderate-to-severe VMS (≥ 7 episodes/week) were eligible. Participants were randomized 1:1 to receive paroxetine 20 mg/day or matching placebo (folic acid 5 mg) for 12 weeks. The primary outcome was change in total Menopause Rating Scale (MRS) score. Secondary outcomes included quality of life (SF-36) and adverse events. Analysis followed the per-protocol approach, with intention-to-treat sensitivity analysis.</p><p><strong>Results: </strong>Of 150 women assessed, 90 were randomized. A total of 47 women in the paroxetine group and 43 in the placebo group completed follow-up and were analyzed. At 12 weeks, the paroxetine group showed greater reduction in total MRS score compared with placebo (mean 16.9 ± 7.7 vs. 22.6 ± 6.1; mean difference -5.7, 95% CI -8.6 to -2.8; P < 0.001). SF-36 scores also improved more with paroxetine (91.0 ± 6.4 vs. 86.9 ± 4.8; mean difference 4.1, 95% CI 1.7 to 6.5; P = 0.001). Adverse events (headache, fatigue, drowsiness) were more frequent with paroxetine but mild and transient; no serious events occurred. The dropout rate was 14.4% (13/90), and intention-to-treat analysis showed consistent findings with slightly attenuated effect sizes.</p><p><strong>Conclusion: </strong>In this pilot study, paroxetine 20 mg/day showed promise in reducing VMS and improving quality of life in Honduran women with surgical menopause, with acceptable tolerability. The high attrition rate underscores the need for larger trials to confirm these findings.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"779-788"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147987544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of ex-utero collection for umbilical cord blood banking: A randomized clinical trial comparing cord blood quality with the in-utero technique. 评估脐带血库的体外采集:一项比较脐带血质量与子宫内技术的随机临床试验。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-06-04 DOI: 10.1002/ijgo.71086
Nimet Ozbey, Elisenda Farssac, Sandra García Martínez, Nerea Castillo, Alberto Rodriguez-Melcon, Sergi Querol, Jesus Fernandez-Sojo, Pilar Prats
{"title":"Evaluation of ex-utero collection for umbilical cord blood banking: A randomized clinical trial comparing cord blood quality with the in-utero technique.","authors":"Nimet Ozbey, Elisenda Farssac, Sandra García Martínez, Nerea Castillo, Alberto Rodriguez-Melcon, Sergi Querol, Jesus Fernandez-Sojo, Pilar Prats","doi":"10.1002/ijgo.71086","DOIUrl":"10.1002/ijgo.71086","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Umbilical cord blood (UCB) can be collected in utero (before placental delivery) or ex utero (after placental delivery). While in utero collection is standard, ex utero collection is less intrusive during birth and better tolerated by mothers. However, its efficiency remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective(s): &lt;/strong&gt;The primary objective was to demonstrate that ex utero umbilical cord blood (UCB) collection is non-inferior to in utero collection in terms of UCB unit weight, as a surrogate of collected volume. Secondary objectives were to confirm that progenitor cells obtained ex utero meet established quality criteria and that the method yields a lower rate of bacterial contamination.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design: &lt;/strong&gt;We conducted a prospective, unblinded, randomized clinical trial (from September 2023 to September 2024) at Hospital Universitari Dexeus and with the Concordia Cord Blood Program in Barcelona (Barcelona Cord Blood Bank) registered at ClinicalTrials.gov (Identifier: NCT05836974). Pregnant women were randomized 1:1 to ex utero or in utero collection. In the experimental arm, UCB was collected after placental delivery on a surgical table; in the control arm, collection occurred before placental delivery. In both arms, the cord was clamped 1 min after birth. A minimum UCB weight of 85 g was required. They were then distributed for further processing in: (i) research biobank/culture media (85-100 g); (ii) multicomponent use (&gt;100 g with &lt;1.5 × 10&lt;sup&gt;9&lt;/sup&gt; nucleated cells); or (iii) transplantation (&gt;100 g with &gt;1.5 × 10&lt;sup&gt;9&lt;/sup&gt; nucleated cells). Secondary endpoints included total nucleated cell (TNC) count, red blood cells count, hematocrit, platelets, and bacteriology, assessed only in units designated for clinical use.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of 133 patients screened, 129 were randomized. Following exclusions (10 in the in utero group and 18 in the ex utero group), a total of 53 in utero collections and 48 ex utero collections were analyzed. Baseline characteristics, including maternal age, gestational age, type of delivery, and newborn gender, were similar. The mean weight of the UCB was 107.19 ± 29.51 g ex utero and 110.81 ± 29.62 g in utero, resulting in a mean difference of -3.62 g (95% confidence interval [CI] -13.41; 6.16 g). The proportion of UCB units below 85 g was comparable between the groups. Both methods showed a similar distribution pattern. Bacteriology (number of samples tested were 35 in utero, 22 ex utero) yielded one positive culture in each group. Total nucleated cell counts, red blood cell counts, and hematocrit and platelet counts did not differ significantly between collection methods.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion(s): &lt;/strong&gt;Ex utero UCB collection is non-inferior to the standard in utero method in terms of UCB weight, cellular composition, and contamination rates. With standardized procedures, ex utero collection is a clinically viable alternative to facilitate","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"911-920"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148156416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobility-enabling birth beds versus traditional gynecological tables: A quasi-experimental study of birth experiences and clinical outcomes. 可移动的分娩床与传统的妇科手术台:一项关于分娩经验和临床结果的准实验研究。
IF 2.7 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2026-11-01 Epub Date: 2026-06-08 DOI: 10.1002/ijgo.71117
Ayşe Taştekin, Özlem Durmuş Tekin
{"title":"Mobility-enabling birth beds versus traditional gynecological tables: A quasi-experimental study of birth experiences and clinical outcomes.","authors":"Ayşe Taştekin, Özlem Durmuş Tekin","doi":"10.1002/ijgo.71117","DOIUrl":"10.1002/ijgo.71117","url":null,"abstract":"<p><strong>Objective: </strong>This study compares birth experiences and clinical outcomes between women giving birth using mobility-enabling labor-birth-postpartum (LBP) beds and those using a traditional gynecological table (TGT).</p><p><strong>Methods: </strong>This quasi-experimental study was conducted between June and October 2025 in a secondary-level maternity unit in Turkey. A total of 320 women who had vaginal births were sequentially assigned to either the LBP group (n = 160) or the TGT group (n = 160). Continuous variables were analyzed using Mann-Whitney U-tests, with Bonferroni correction applied for multiple comparisons, and categorical variables using χ<sup>2</sup>-tests.</p><p><strong>Results: </strong>Baseline characteristics were comparable between groups. Regarding the primary outcome, no significant difference in labor duration was observed between the groups (P = 0.254). After multiplicity adjustment, episiotomy (45.0% vs. 67.5%) and fundal compression (6.9% vs. 25.0%) were significantly less frequent in the LBP group (P < 0.001). Women using LBP beds reported lower pain scores and higher birth satisfaction (P < 0.001). There were no statistically significant differences between the groups in neonatal variables after adjusting the significance threshold (P > 0.0029).</p><p><strong>Conclusion: </strong>These results suggest that while mobility-enabling LBP beds do not shorten labor duration, they are associated with a substantial reduction in obstetric interventions from extremely high institutional levels and enhanced maternal birth experiences. By supporting maternal movement and positional flexibility, these beds may facilitate physiologic labor and represent a practical strategy for strengthening woman-centered intrapartum care. However, environmental modifications should be integrated with broader institutional policy shifts to fully align with global evidence-based standards and further reduce the need for routine interventions.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":"960-968"},"PeriodicalIF":2.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148198832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书