Laura E Davis,Hailey R Banack,Renzo Calderon-Anyosa,Erin C Strumpf,Alyson L Mahar
{"title":"Probabilistic bias analysis for exposure misclassification of household income by neighbourhood in a cohort of individuals with colorectal cancer.","authors":"Laura E Davis,Hailey R Banack,Renzo Calderon-Anyosa,Erin C Strumpf,Alyson L Mahar","doi":"10.1093/ije/dyae135","DOIUrl":"https://doi.org/10.1093/ije/dyae135","url":null,"abstract":"INTRODUCTIONDespite poor agreement, neighbourhood income is used as a proxy for household income, due to a lack of data availability. We quantified misclassification between household and neighbourhood income and demonstrate quantitative bias analysis (QBA) in scenarios where only neighbourhood income is available in assessing income inequalities on colorectal cancer mortality.METHODSThis was a retrospective study of adults with colorectal cancer diagnosed 2006-14 from Statistics Canada's Canadian Census Health and Environment Cohort. Neighbourhood income quintiles from Statistics Canada were used. Census household income quintiles were used to determine bias parameters and confirm results of the QBA. We calculated positive and negative predictive values using multinomial models, adjusting for age, sex and rural residence. Probabilistic QBA was conducted to explore the implication of exposure misclassification when estimating the effect of income on 5-year mortality.RESULTSWe found poor agreement between neighbourhood and household income: positive predictive values ranged from 21% to 37%. The bias-adjusted risk of neighbourhood income on 5-year mortality was similar to the risk of mortality by household income. The bias-adjusted relative risk of the lowest income quintile compared with the highest was 1.42 [95% simulation interval (SI) 1.32-1.53] compared with 1.46 [95% confidence interval (CI) 1.39-1.54] for household income and 1.18 (95% CI 1.12-1.24) for neighbourhood income.CONCLUSIONQBA can be used to estimate adjusted effects of neighbourhood income on mortality which represent household income. The predictive values from our study can be applied to similar cohorts with only neighbourhood income to estimate the effects of household income on cancer mortality.","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"55 1","pages":""},"PeriodicalIF":7.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142436159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to write an effective journal peer review using a staged writing approach: a best-practice guide for early-career researchers.","authors":"Ella T August, Andrew F Brouwer","doi":"10.1093/ije/dyae154","DOIUrl":"10.1093/ije/dyae154","url":null,"abstract":"<p><p>Journal peer review is a gatekeeper in the scientific process, determining which papers are published in academic journals. It also supports authors in improving their papers before they go to press. Training for early-career researchers on how to conduct a high-quality peer review is scarce, however, and there are concerns about the quality of peer review in the health sciences. Standardized training and guidance may help reviewers to improve the quality of their feedback. In this paper, we approach peer review as a staged writing activity and apply writing process best practices to help early-career researchers and others learn to create a comprehensive and respectful peer-review report. The writing stages of reading, planning and composing are reflected in our three-step peer-review process. The first step involves reading the entire manuscript to get a sense of the paper as a whole. The second step is to comprehensive evaluate the paper. The third step, of writing the review, emphasizes a respectful tone, providing feedback that motivates revision as well as balance in pointing out strengths and making suggestions. Detailed checklists that are provided in the Supplementary material (available as Supplementary data at IJE online) aid in the paper evaluation process and examples demonstrate points about writing an effective review.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A cautionary note on the recently proposed ICE Falcon method.","authors":"Arvid Sjölander, Thomas Frisell","doi":"10.1093/ije/dyae131","DOIUrl":"https://doi.org/10.1093/ije/dyae131","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11438546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenny Chanfreau, Katherine Keenan, Kieron Barclay, Alice Goisis
{"title":"The midlife health of only children: chronic disease indicators and biomarkers by sibship size in three nationally representative UK cohorts.","authors":"Jenny Chanfreau, Katherine Keenan, Kieron Barclay, Alice Goisis","doi":"10.1093/ije/dyae119","DOIUrl":"10.1093/ije/dyae119","url":null,"abstract":"<p><strong>Background: </strong>Despite persistent concerns about only children's disadvantage relative to individuals with siblings, existing health-related evidence is inconsistent. Recent evidence from Nordic countries about only children having poorer health outcomes may not apply elsewhere because selection processes differ across contexts. We investigate the midlife health of only children in the UK where one-child families tend to be socio-economically advantaged relative to large families.</p><p><strong>Methods: </strong>Using the 1946, 1958 and 1970 British birth cohort studies, we examine various biomarkers and self-reported measures of chronic disease by sibship size when respondents are aged in their mid-40s, mid-50s and mid-60s. We estimate separate linear probability models for each cohort, age and outcome, adjusting for childhood and early adulthood circumstances.</p><p><strong>Results: </strong>We found no evidence of only children differing from those with one, two or three or more siblings, at any age, in any of the cohorts, on: heart problems, hypertension, high triglycerides, high glycated haemoglobin or high C-reactive protein. However, compared with only children, the probability for cancer (0.019, 95% confidence interval [CI]: 0.002, 0.035; age 46/1970) and poor general health (0.060, CI: 0.015, 0.127; age 55/1958; and 0.110, CI: 0.052, 0.168; age 63/1946) was higher among those with three or more siblings.</p><p><strong>Conclusions: </strong>There is no consistent pattern of only child health disadvantage for midlife chronic disease outcomes across ages or cohorts in the UK. Research should focus on better understanding how sibship size differentials are contingent on context.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew A Jay, Lauren Herlitz, Jessica Deighton, Ruth Gilbert, Ruth Blackburn
{"title":"Cumulative incidence of chronic health conditions recorded in hospital inpatient admissions from birth to age 16 in England.","authors":"Matthew A Jay, Lauren Herlitz, Jessica Deighton, Ruth Gilbert, Ruth Blackburn","doi":"10.1093/ije/dyae138","DOIUrl":"10.1093/ije/dyae138","url":null,"abstract":"<p><strong>Background: </strong>Monitoring the incidence of chronic health conditions (CHCs) in childhood in England, using administrative data to derive numerators and denominators, is challenged by unmeasured migration. We used open and closed birth cohort designs to estimate the cumulative incidence of CHCs to age 16 years.</p><p><strong>Methods: </strong>In closed cohorts, we identified all births in Hospital Episode Statistics (HES) from 2002/3 to 2011/12, followed to 2018/19 (maximum age 8 to 16 years), censoring on death, first non-England residence record or 16th birthday. Children must have linked to later HES records and/or the National Pupil Database, which provides information on all state school enrolments, to address unmeasured emigration. The cumulative incidence of CHCs was estimated to age 16 using diagnostic codes in HES inpatient records. We also explored temporal variation. Sensitivity analyses varied eligibility criteria. In open cohorts, we used HES data on all children from 2002/3 to 2018/19 and national statistics population denominators.</p><p><strong>Results: </strong>In open and closed approaches, the cumulative incidence of ever having a CHC recorded before age 16 among children born in 2003/4 was 25% (21% to 32% in closed cohort sensitivity analyses). There was little temporal variation. At least 28% of children with any CHC had more than one body system affected by age 16. Multimorbidity rates rose with later cohorts.</p><p><strong>Conclusions: </strong>Approximately one-quarter of children are affected by CHCs, but estimates vary depending on how the denominator is defined. More accurate estimation of the incidence of CHCs requires a dynamic population estimate.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergey Timonin, David A Leon, Emily Banks, Tim Adair, Vladimir Canudas-Romo
{"title":"Faltering mortality improvements at young-middle ages in high-income English-speaking countries.","authors":"Sergey Timonin, David A Leon, Emily Banks, Tim Adair, Vladimir Canudas-Romo","doi":"10.1093/ije/dyae128","DOIUrl":"10.1093/ije/dyae128","url":null,"abstract":"<p><strong>Background: </strong>Before the COVID-19 pandemic, stagnating life expectancy trends were reported in some high-income countries (HICs). Despite previous evidence from country-specific studies, there is a lack of comparative research that provides a broader perspective and challenges existing assumptions. This study aims to examine longevity trends and patterns in six English-speaking countries (Australia, Canada, Ireland, New Zealand, United Kingdom, United States) by combining period and cohort perspectives and to compare them with other HICs.</p><p><strong>Methods: </strong>Using data from the Human Mortality and World Health Organization Mortality Databases, we estimated partial life expectancy, lifespan inequality and cohort survival differences for 1970-2021, as well as the contribution of causes of death to the gap in life expectancy between English-speaking countries and the average for other HICs in 2017-19.</p><p><strong>Results: </strong>In the pre-pandemic period, the increase in life expectancy slowed in all English-speaking countries, except Ireland, mainly due to stagnating or rising mortality at young-middle ages. Relative to other HICs, those born in Anglophone countries since the 1970s experienced relative survival disadvantage, largely attributable to injuries (mainly suicides) and substance-related mortality (mainly poisonings). In contrast, older cohorts enjoyed advantages for females in Australia and Canada and for males in all English-speaking countries except the United States.</p><p><strong>Conclusions: </strong>Although future gains in life expectancy in wealthy societies will increasingly depend on reducing mortality at older ages, adverse health trends at younger ages are a cause for concern. This emerging and avoidable threat to health equity in English-speaking countries should be the focus of further research and policy action.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahyar Etminan, Ramin Rezaeianzadeh, Mohammad A Mansournia
{"title":"Causal diagrams for disease latency bias.","authors":"Mahyar Etminan, Ramin Rezaeianzadeh, Mohammad A Mansournia","doi":"10.1093/ije/dyae111","DOIUrl":"https://doi.org/10.1093/ije/dyae111","url":null,"abstract":"<p><strong>Background: </strong>Disease latency is defined as the time from disease initiation to disease diagnosis. Disease latency bias (DLB) can arise in epidemiological studies that examine latent outcomes, since the exact timing of the disease inception is unknown and might occur before exposure initiation, potentially leading to bias. Although DLB can affect epidemiological studies that examine different types of chronic disease (e.g. Alzheimer's disease, cancer etc), the manner by which DLB can introduce bias into these studies has not been previously elucidated. Information on the specific types of bias, and their structure, that can arise secondary to DLB is critical for researchers, to enable better understanding and control for DLB.</p><p><strong>Development: </strong>Here we describe four scenarios by which DLB can introduce bias (through different structures) into epidemiological studies that address latent outcomes, using directed acyclic graphs (DAGs). We also discuss potential strategies to better understand, examine and control for DLB in these studies.</p><p><strong>Application: </strong>Using causal diagrams, we show that disease latency bias can affect results of epidemiological studies through: (i) unmeasured confounding; (ii) reverse causality; (iii) selection bias; (iv) bias through a mediator.</p><p><strong>Conclusion: </strong>Disease latency bias is an important bias that can affect a number of epidemiological studies that address latent outcomes. Causal diagrams can assist researchers better identify and control for this bias.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of conventional cigarette smoking, heated tobacco product use and dual use with hypertension.","authors":"Huan Hu, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Tetsuya Mizoue","doi":"10.1093/ije/dyae114","DOIUrl":"10.1093/ije/dyae114","url":null,"abstract":"<p><strong>Background: </strong>Heated tobacco products (HTPs) have emerged as alternatives to conventional cigarettes. However, their health effects remain largely unknown. This study aimed to prospectively explore the association between the use of cigarettes and HTPs and the risk of hypertension.</p><p><strong>Methods: </strong>This cohort study analysed data from 30 152 workers (82.0% men, mean age 42.9 ± 11.0 years) who were initially free of hypertension, participating in the Japan Epidemiology Collaboration on Occupational Health Study. Participants were categorized into five groups based on their self-reported tobacco product use: never smokers, past smokers, exclusive cigarette smokers, exclusive HTP users and dual users of cigarettes and HTPs. Hypertension cases were identified using three data points from annual health checkup data collected between 2019 and 2021. Cox proportional hazards regression models were used to investigate the association between tobacco product use and hypertension.</p><p><strong>Results: </strong>During a mean follow-up of 2.6 years (range: 0.1-4.0 years), 3656 new cases of hypertension were identified. Compared with never smokers, the risk of hypertension was higher among exclusive cigarette smokers [hazard ratio (HR) 1.26, 95% confidence interval (CI) 1.13-1.41] and exclusive HTP users (HR 1.19, 95% CI 1.06-1.34). There was also a suggestion of increased risk of hypertension among dual users (HR 1.16, 95% CI 0.98-1.38). Furthermore, the risk of hypertension increased with the intensity of cigarette/HTP use in all tobacco product users.</p><p><strong>Conclusions: </strong>Similarly, both cigarette smoking and HTP use elevate the risk of hypertension. HTPs should not be regarded as less harmful alternatives to traditional cigarettes for preventing hypertension.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalie V Scime, Sonia M Grandi, Joel G Ray, Cindy-Lee Dennis, Mary A De Vera, Hailey R Banack, Simone N Vigod, Alexa Boblitz, Hilary K Brown
{"title":"Pregnancy complications and new-onset maternal autoimmune disease.","authors":"Natalie V Scime, Sonia M Grandi, Joel G Ray, Cindy-Lee Dennis, Mary A De Vera, Hailey R Banack, Simone N Vigod, Alexa Boblitz, Hilary K Brown","doi":"10.1093/ije/dyae115","DOIUrl":"10.1093/ije/dyae115","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune diseases disproportionately impact women and female-specific aspects of reproduction are thought to play a role. We investigated the time-varying association between pregnancy complications and new-onset autoimmune disease in females during the reproductive and midlife years.</p><p><strong>Methods: </strong>We conducted a population-based cohort study of 1 704 553 singleton births to 1 072 445 females in Ontario, Canada (2002-17) with no pre-existing autoimmune disease. Pregnancy complications were preeclampsia, stillbirth, spontaneous preterm birth and severe small for gestational age (SGA). Royston-Parmar models were used to estimate the time-varying association between pregnancy complications and a composite of 25 autoimmune diseases from date of delivery to date of autoimmune disease diagnosis or censoring at death, loss of health insurance, or 31 March 2021. Models were adjusted for baseline socio-demographics, parity and comorbidities.</p><p><strong>Results: </strong>At 19 years (median = 10.9 years of follow-up), cumulative incidence of autoimmune disease was 3.1% in those with a pregnancy complication and 2.6% in those without complications. Adjusted hazard ratio (AHR) curves as a function of time since birth were generally L-shaped. Universally, risks were most elevated within the first 3 years after birth [at 1 year: preeclampsia AHR 1.22, 95% confidence interval (CI) 1.09-1.36; stillbirth AHR 1.36, 95% CI 0.99-1.85; spontaneous preterm birth AHR 1.30, 95% CI 1.18-1.44; severe SGA AHR 1.14, 95% CI 0.99-1.31] and plateaued but remained elevated thereafter.</p><p><strong>Conclusions: </strong>Prior history of pregnancy complications may be an important female-specific risk factor to consider during clinical assessment of females for possible autoimmune disease to facilitate timely detection and treatment.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 5","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth M Lawrence,Elyssa A Trani,Kurtis M Anthony,Robert A Hummer,Tiffany Jensen,Sylvie Tuder,Laura R Loehr,Kathleen Mullan Harris,Eric A Whitsel
{"title":"Data Resource Profile: Add Health Mortality Outcomes Surveillance.","authors":"Elizabeth M Lawrence,Elyssa A Trani,Kurtis M Anthony,Robert A Hummer,Tiffany Jensen,Sylvie Tuder,Laura R Loehr,Kathleen Mullan Harris,Eric A Whitsel","doi":"10.1093/ije/dyae121","DOIUrl":"https://doi.org/10.1093/ije/dyae121","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"1 1","pages":""},"PeriodicalIF":7.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142263997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}