Joonas Pitkänen, Amir Sariaslan, Lauren Bishop, Pekka Martikainen
{"title":"Childhood household dysfunction and psychiatric, criminal, and social outcomes in emerging adulthood. A cousin comparison study.","authors":"Joonas Pitkänen, Amir Sariaslan, Lauren Bishop, Pekka Martikainen","doi":"10.1093/ije/dyaf074","DOIUrl":"10.1093/ije/dyaf074","url":null,"abstract":"<p><strong>Background: </strong>Childhood household dysfunction is a well-known risk factor for adverse medical and social outcomes. However, less is known about the extent to which such associations are affected by unmeasured familial confounding.</p><p><strong>Methods: </strong>This cohort study is based on Finnish register data on birth cohorts 1987-2000 (n = 835 987). We considered parental hospital-presenting substance use and psychiatric disorders, prison sentences, death, means-tested social assistance, and union dissolution at ages 0-14 as indicators of childhood household dysfunction. The study participants were followed from age 15 until the end of 2020 for hospital-presenting psychiatric disorders and substance use, psychotropic medication purchases, violent and property crime arrests, and not being in education, employment, or training. The associations were estimated using Cox regression, and cousin comparisons were used to account for unmeasured confounders shared within extended families (n = 87 500).</p><p><strong>Results: </strong>All the exposures were associated with the outcomes in the population-level models, with hazard ratios ranging from 1.3 (95% confidence interval 1.3-1.4) to 2.5 (2.4-2.6). The associations attenuated in the cousin comparisons, on average 12% but with a wide range from -2% to 39% [hazard ratios ranging from 1.2 (1.1-1.4) to 1.9 (1.6-2.3)]. A dose-response relationship between the exposures and the outcomes was observed in the population-level models and the cousin comparisons, with attenuated associations in the latter.</p><p><strong>Conclusion: </strong>Our findings show systematic associations between childhood household dysfunction and subsequent outcomes. Unobserved confounding likely creates upward bias in these associations, but the extent of this confounding depends on the specific exposure-outcome pairs.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enny S Paixao, Deborah A Lawlor, Mauricio L Barreto, Laura C Rodrigues
{"title":"Integrating infectious diseases into life course epidemiology.","authors":"Enny S Paixao, Deborah A Lawlor, Mauricio L Barreto, Laura C Rodrigues","doi":"10.1093/ije/dyaf059","DOIUrl":"10.1093/ije/dyaf059","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Abbadi, Martin Eklund, Markus Aly, Mark Clements, Alessio Crippa, Andrea Discacciati, Astrid Björklund, Vivekananda Lanka, Chiara Micoli, Anna Lantz, Henrik Grönberg, Tobias Nordström
{"title":"Data Resource Profile: STHLM0, the Stockholm Prostate Cancer Diagnostics Register.","authors":"Ahmad Abbadi, Martin Eklund, Markus Aly, Mark Clements, Alessio Crippa, Andrea Discacciati, Astrid Björklund, Vivekananda Lanka, Chiara Micoli, Anna Lantz, Henrik Grönberg, Tobias Nordström","doi":"10.1093/ije/dyaf062","DOIUrl":"10.1093/ije/dyaf062","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Efstate, Vivienne M Hazzard, Natasha L Burke, Kendrin R Sonneville, David Hammond
{"title":"Food security and eating disorder behaviors in the International Food Policy Study, 2018 to 2022.","authors":"Anna Efstate, Vivienne M Hazzard, Natasha L Burke, Kendrin R Sonneville, David Hammond","doi":"10.1093/ije/dyaf060","DOIUrl":"10.1093/ije/dyaf060","url":null,"abstract":"<p><strong>Background: </strong>A link has been established between food insecurity and eating disorder (ED) pathology, but most research on this topic has occurred in the USA. This study examined associations and potential moderators of associations between food security (FS) levels and ED behaviors cross-nationally.</p><p><strong>Methods: </strong>Repeated cross-sectional data representing 104 881 adults 18-100 years of age in Australia, Canada, Mexico, the UK, and the USA came from five waves (2018-22) of the International Food Policy Study. Participants completed the Household Food Security Survey Module and reported on past-3-month binge eating and self-induced vomiting to control weight. Associations between past-year household FS level and ED behaviors were examined with adjusted modified Poisson regression models. Interactions with potential moderators were also tested.</p><p><strong>Results: </strong>Marginal, low, and very low FS were associated with elevated prevalence of both ED behaviors. Compared with households with high FS, binge eating was 1.34, 1.54, and 1.73 times as prevalent in households with marginal, low, and very low FS, respectively. Associations were stronger for self-induced vomiting; compared with households with high FS, self-induced vomiting was 2.40, 7.10, and 11.98 times as prevalent in households with marginal, low, and very low FS, respectively. Moderation results revealed meaningful differences by some factors. For example, associations were weaker in Mexico and stronger among ethnic minorities and participants with children.</p><p><strong>Conclusion: </strong>Results support cross-sectional associations between FS and ED behaviors, with a particularly strong link for self-induced vomiting. Some heterogeneity in these associations was observed across country and sociodemographic factors.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Probst, Sophie Bright, Yachen Zhu, Carolin Kilian, Charlotte Buckley, Yu Ye, Nina Mulia, William C Kerr, Jürgen Rehm
{"title":"The COVID-19 syndemic: a perfect storm for the life expectancy of the most disadvantaged Americans.","authors":"Charlotte Probst, Sophie Bright, Yachen Zhu, Carolin Kilian, Charlotte Buckley, Yu Ye, Nina Mulia, William C Kerr, Jürgen Rehm","doi":"10.1093/ije/dyaf069","DOIUrl":"10.1093/ije/dyaf069","url":null,"abstract":"<p><strong>Background: </strong>To explore the syndemic nature of the COVID-19 pandemic by identifying which subpopulations in the United States (US) suffered the greatest losses in life expectancy (LE) in 2020 and 2021, and to which extent these losses can be attributed to COVID-19 and 'other' causes of death.</p><p><strong>Methods: </strong>We analysed individual death records for 2018-2021 from the National Vital Statistics System and population counts from the American Community Survey. Life table and continuous change decomposition analyses were used to quantify cause-/.specific contributions to changes in LE over time in population subgroups defined by sex, educational attainment, and race/ethnicity.</p><p><strong>Results: </strong>From 2019 to 2020, educational differences in LE (high minus low education) increased substantially by 5.0 and 2.6 years in Hispanic men and women, respectively, with increases of one to two years among Black and White adults. Nearly all losses in LE among high-education Hispanic and White groups were due to COVID-19, while among low-education White and Black groups, COVID-19 accounted for 40%-47% of the total losses in LE. Changes in LE were much smaller during 2020-2021.</p><p><strong>Conclusions: </strong>COVID-19 widened preexisting inequalities in LE in the US, both via direct mortality and through syndemic interactions with other diseases and health conditions. The underlying social, political, economic, and environmental factors driving the clustering and interaction of diseases among the most disadvantaged Americans need to be addressed.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henrike Galenkamp, Anitra D M Koopman, J Esi van der Zwan, Bert-Jan H van den Born, Anja Lok, Eric P Moll van Charante, Maria Prins, Arnoud P Verhoeff, Aeilko H Zwinderman, Karien Stronks
{"title":"Cohort Profile Update: The Healthy Life in an Urban Setting (HELIUS) Study.","authors":"Henrike Galenkamp, Anitra D M Koopman, J Esi van der Zwan, Bert-Jan H van den Born, Anja Lok, Eric P Moll van Charante, Maria Prins, Arnoud P Verhoeff, Aeilko H Zwinderman, Karien Stronks","doi":"10.1093/ije/dyaf071","DOIUrl":"10.1093/ije/dyaf071","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hangjie Zhu, Yang Zhao, Nan Li, He Ye, Dongfang You, Bangyu Wang, Yi Qian, Mengyuan Liang, Kunyi Wang, Yisheng Zhang, Ling Tang, Dong Ye, Liya Liu
{"title":"Data Resource Profile: The Ningbo MATernity-CHild LinkEd databaSe Study (MATCHLESS).","authors":"Hangjie Zhu, Yang Zhao, Nan Li, He Ye, Dongfang You, Bangyu Wang, Yi Qian, Mengyuan Liang, Kunyi Wang, Yisheng Zhang, Ling Tang, Dong Ye, Liya Liu","doi":"10.1093/ije/dyaf073","DOIUrl":"https://doi.org/10.1093/ije/dyaf073","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harold H Lee, Ruijia Chen, Sakurako S Okuzono, Laura D Kubzansky
{"title":"Loneliness and cardiovascular disease incidence: two cohorts of older adults in the USA and South Korea.","authors":"Harold H Lee, Ruijia Chen, Sakurako S Okuzono, Laura D Kubzansky","doi":"10.1093/ije/dyaf050","DOIUrl":"https://doi.org/10.1093/ije/dyaf050","url":null,"abstract":"<p><strong>Background: </strong>We investigated the relationship between loneliness and cardiovascular disease (CVD) in older adults from the USA and South Korea. We conducted counterfactual mediation analyses to explore the potential mediation of this relationship by health behaviors.</p><p><strong>Methods: </strong>We used the Health and Retirement Study (HRS; n = 13 073) from the USA and the Korean Longitudinal Study of Aging (KLoSA; n = 8311) from South Korea. In both cohorts, baseline loneliness was assessed using one item from the Center for Epidemiologic Studies Depression Scale. Incident CVD was defined as reporting new-onset CVD on the biennial questionnaire or CVD death reported by proxies. Within each cohort, we estimated adjusted hazard ratios (aHRs) of incident CVD according to loneliness (yes/no) over 12-14 years of follow-up, adjusting for baseline covariates: social isolation, sociodemographic factors, health conditions, and health behaviors.</p><p><strong>Results: </strong>Feeling lonely was associated with an increased likelihood of developing CVD in the USA (aHR: 1.15, 95% CI: 1.04, 1.27) and South Korea (aHR: 1.16, 95% CI: 1.00, 1.34). Several behaviors accounted for a proportion of the association: physical activity (14.3%, P = 0.03 in HRS; 1.3%, P = 0.04 in KLoSA) and alcohol (3.9%, P < 0.001 in HRS; 1.3%, P < 0.001 in KLoSA) in both countries, smoking only in HRS (4.7%, P < 0.001).</p><p><strong>Conclusion: </strong>The magnitude of the impact of loneliness on CVD was similar in both countries, but behavioral pathways differed. Loneliness may be a risk factor for CVD regardless of culture; however, different prevention strategies in clinical settings may be required.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeppe K Sørensen, Louise Dalsager, Lars L Andersen, Hans Bay, Anne H Garde, Nina F Johnsen, Nanna P Larsson, Ida E H Madsen, Jacob Pedersen, Vivi Schlünssen, Kathrine Sørensen, Reiner Rugulies
{"title":"Cohort Profile: the Work Environment and Health in Denmark study.","authors":"Jeppe K Sørensen, Louise Dalsager, Lars L Andersen, Hans Bay, Anne H Garde, Nina F Johnsen, Nanna P Larsson, Ida E H Madsen, Jacob Pedersen, Vivi Schlünssen, Kathrine Sørensen, Reiner Rugulies","doi":"10.1093/ije/dyaf085","DOIUrl":"10.1093/ije/dyaf085","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"54 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}