International Journal of Mental Health and Addiction最新文献

{"title":"Unpacking the Myth in the Associations Between Self-control and Gaming Disorder in Children and Adolescents: A Comparison Between Traditional and Random Intercept Cross-lagged Panel Model Analyses","authors":"Di QI, Xiaomin LI, Shimin ZHU","doi":"10.1007/s11469-024-01294-0","DOIUrl":"https://doi.org/10.1007/s11469-024-01294-0","url":null,"abstract":"<p>Internet gaming is becoming increasingly popular; however, children and adolescents are highly vulnerable to gaming disorder due to the underdevelopment of cognitive control. Longitudinal research providing empirical evidence confirming the stability and direction of the association between self-control and gaming disorder is scarce. This study is aimed at clarifying whether prospective relationships exist between self-control and gaming disorder in children and adolescents or whether they are associated due to common causes. We examined the temporal dynamics of the associations between self-control and gaming disorder symptom severity using a traditional cross-lagged panel model (CLPM; aggregating between- and within-person variance) and a random intercept CLPM (RI-CLPM; disaggregating between- and within-person effects) with three-annual wave data from a large cohort of primary and secondary students (<i>N</i> = 1359, mean age 12.67 (<i>SD</i> 1.40), 834 (61.7%) girls). The traditional CLPM indicated a unidirectional negative relationship from self-control to later gaming disorder (<i>B</i> with 95% confidence interval [CI] = − 0.12 [− 0.19, − 0.040]), whereas the RI-CLPM analysis revealed no prospective relationship between self-control and gaming disorder (95% CIs of <i>B</i>s all contain 0), indicating that self-control was neither the cause nor the result of gaming disorder in children and adolescents. Our study revealed that the nature of the relationship between self-control and gaming disorder tends to be correlational but not causal. The potential common underlying factors for future research are discussed.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"8 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabidiol Compared to Pharmacological Treatment as Usual for Crack Use Disorder: A Feasibility, Preliminary Efficacy, Parallel, Double-Blind, Randomized Clinical Trial","authors":"Andrea Donatti Gallassi, André Wagner Carvalho de Oliveira, Larissa Alencar Rodrigues, Eduardo Yoshio Nakano, Pedro A. S. Ruas, José Antonio Iturri de La Mata, Ettore Ferrari Júnior, Juliano de Andrade Gomes, Mariana Emanuele Silva Caroba, Marianna Gabriella dos Santos Silva, Mariana G. Q. Vieira, Julia G. G. R. Reis, Jade Luiza Moreira Leite, Guilherme Henrique Alves de Lima, Jonathan Morais Lima, Yasmim P. V. Lima, Jorge A. A. Ribas, Nathalia A. L. das Chagas, Mateus A. Magalhães, Mateus F. da Silva, Renato Filev, Renato Malcher-Lopes","doi":"10.1007/s11469-024-01287-z","DOIUrl":"https://doi.org/10.1007/s11469-024-01287-z","url":null,"abstract":"<p>Cannabidiol (CBD) has been studied for substance use disorders treatment due to its anxiolytic effects, for sleep, appetite, reduction of craving, and maintenance of abstinence. The study aims to assess CBD’s feasibility, safety/tolerability, and preliminary efficacy compared to pharmacological treatment as usual for reducing crack use in people with crack use disorder (CUD) and investigate other parameters: adverse events, physical health symptoms, and craving. A double-blind, randomized clinical trial (RCT) with two treatment arms (CBD and control group) was conducted. Ninety participants were randomized and 73 were allocated: 37 control group and 36 CBD group for a 10-week treatment, comparing CBD (600 mg) with three drugs (fluoxetine, valproic acid, and clonazepam). The per-protocol analysis of participants who did not deviate from the study protocol compared the control and CBD treatment groups. Thirty-four completed at least half of the study and 25 finished. Participants attended weekly meetings for the study procedures (e.g., to receive the medication and provide urine for toxicological tests). Inter-group differences were performed with the Mann–Whitney test, the Wilcoxon test for differences intra-group, and Pearson’s Chi-square test or Fisher’s exact test to compare inter-group demographic data. The significance level was 5%. A “veracity index” (VI) was created as counterevidence (questionnaire data vs. the toxicological test result). Medications were considered safe/tolerable. The CBD group presented significantly fewer adverse events compared to the control group [e.g., dizziness (<i>p</i> = 0.001), memory impairment (<i>p</i> = 0.043)], which performed better in the reduction of clinical and psychiatric complaints (<i>p</i> = 0.008). In the intra-group analyses, the CBD group performed better in more parameters than the control group [e.g., reducing crack use (<i>p</i> = 0.016; T0 to T1)]. Data questionnaires were reliable regarding the use/non-use of crack (VI = 0.787). CBD is a safe/tolerable product. The CBD group manifested fewer adverse events than the control group, which had better clinical and psychiatric complaints results. There are some advantages for the CBD group in the intra-group analysis. Drug use self-report methodologies can be reliable. Trial registration details: This study is registered with Universal Trial Number (UTN) code: U1111-1234-0806. Available at https://ensaiosclinicos.gov.br/rg/RBR-4stgs8 (<i>Effect of cannabidiol in the treatment of crack dependents</i>)</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"18 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing Academic Burnout’s Relationship with Problematic Internet Use and Specific Health-Risk Behaviours: A Cross-sectional Study of Finnish Higher Education Students","authors":"","doi":"10.1007/s11469-024-01290-4","DOIUrl":"https://doi.org/10.1007/s11469-024-01290-4","url":null,"abstract":"<h3>Abstract</h3> <p>Problematic Internet use is recognised as an emerging public health issue, particularly among young adults. Yet, there is scarce information on problematic Internet use as a predictor for academic burnout. This study aimed to identify academic burnout’s association with both problematic Internet use and specific health-risk behaviour among higher education students. We analysed the population-based cross-sectional survey data (with post-stratification weighting) of Finnish higher education students. Data was collected in 2021 (<em>n</em> = 6258; age 18–34). Regression analyses were used to investigate academic burnout’s relationship with problematic Internet use and health-risk behaviours. The results revealed that female gender, learning difficulties, the use snus (the Swedish-type of moist snuff), problematic Internet use, online shopping, and perceived loneliness were significantly and positively associated with academic burnout. In addition, a higher number of study credits earned, self-perceived good health, and a satisfactory financial level were significantly and inversely associated with academic burnout. The findings suggest that screening students for problematic behaviour and offering support for those in need are likely to be effective at increasing academic well-being among higher education students.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"17 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Country Differences in the Effects of Individual Traits on Depression in Women in Europe","authors":"M. Carolina Rodríguez-Donate, Imanol L. Nieto-González, Ginés Guirao-Pérez","doi":"10.1007/s11469-024-01289-x","DOIUrl":"https://doi.org/10.1007/s11469-024-01289-x","url":null,"abstract":"<p>Mental health and, in particular, depression are of great global concern today, especially in middle- and high-income countries. These health issues show an unequal gender prevalence as they are more common in women than in men. The aim of this work is to use micro-econometric models to analyze the prevalence of depression in women in 27 European countries, as well as to quantify the effects of certain individual characteristics on the probability of experiencing depression and the degree to which it occurs. In addition, measures are proposed to assess how each country differs from the total sample. The data used proceed from the European Health Interview Survey wave 2 (EHIS-2). The results show that higher educational levels and incomes are protective factors, while older age and being unemployed have a positive effect on the probability of having depression, particularly on the probability of severe depression. Furthermore, from the calculation of ratios, notable differences are detected in the effects of these characteristics in different countries. Although the direction of the effect of each characteristic is similar in all countries, the size of the effect in each country varies significantly from the sample average. The results highlight the importance of identifying which individual traits generate a higher propensity to experience depression in women. The proposed procedure leads to the conclusion that the detection of differences and similarities between countries could allow the extrapolation of successful practices in prevention and mental health care.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"80 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Simple Risk Calculator for Alcohol-Related Adverse Outcomes: Results from a Composite Scale Approach in a Nationally Representative Sample","authors":"Nicolas Hoertel, Marie Dosquet, Marina Sánchez-Rico, Jesús Godino-Cruz, Carlos Blanco, Henri-Jean Aubin, Géraldine Ducoutumany, Philip Gorwood, Henri Leleu, Guillaume Airagnes, Cédric Lemogne, Katayoun Rezaei, Hugo Peyre, Frédéric Limosin","doi":"10.1007/s11469-024-01278-0","DOIUrl":"https://doi.org/10.1007/s11469-024-01278-0","url":null,"abstract":"<p>We tested how 5 simple variables, routinely collected in primary care (i.e., the 3 AUDIT-C items, age, and sex), could constitute a clinician-friendly risk calculator tool of the 3-year risk of several alcohol-related adverse outcomes (i.e., alcohol use disorder, withdrawal symptoms, occurrence of tremors or seizures, and alcohol related interpersonal relationship problems, legal problems, and psychological problems) among non-alcohol-dependent individuals consuming alcohol. Data were drawn from a nationally representative sample of US adults, the National Epidemiologic Survey on Alcohol and Related Conditions (wave 1, 2001–2002; wave 2, 2004–2005). We used scaled and rounded composite scoring systems to combine information derived from these predictors and quantify the risks for each subject. Analyses were limited to 16,710 respondents without a lifetime history of alcohol use disorder who completed both interviews and had consumed alcohol during the year prior to wave 1 (development sample <i>N</i> = 8355, validation sample <i>N</i> = 8355). The risk equations calibrated well (Hosmer and Lemeshow test <i>p</i> values ≥ 0.072) and showed good predictive values (<i>C</i> indices ranging from 0.727 to 0.872) in the validation sample. This risk calculator can be clinically useful in primary care for identification of at-risk individuals, encourage respondents to reduce their drinking, and improve prevention.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"261 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use and Knowledge Around Vaping and Their Correlates Among University Students—A Cross-sectional Australian Study","authors":"Janni Leung, Rhiannon Ellem, Sophia Glasgow, Amy-Leigh Rowe, Lauren Gardner, Lily Davidson, Gabrielle Campbell, Nina Pocuca, Calvert Tisdale, Gary Chan, Leanne Hides","doi":"10.1007/s11469-024-01281-5","DOIUrl":"https://doi.org/10.1007/s11469-024-01281-5","url":null,"abstract":"<p>The increasing prevalence of e-cigarette use (“vaping”) among youth has emerged as a public health concern. We aim to explore vape use, knowledge levels, and correlates in a sample of Australian young adults. Participants from six residential university colleges in Queensland, Australia, were invited to complete an online survey. The sample included 716 students (<i>M</i>_age=18.1 years). Correlates of vape use and knowledge examined included socio-demographic variables, other substance use, and mental health, including PHQ-9 depression and GAD-7 anxiety. In our sample, 62% of students reported lifetime vaping. Just under half (47.5%) of the sample had used flavour with nicotine vapes, 18.0% had used flavour only, and 2.8% had used other drugs. Past month vaping rates were low at 4.2% for daily use of flavour with nicotine vapes. Co-use of cigarettes was observed with nicotine vapes but most only vaped occasionally. A substantial proportion lacked knowledge about the legality (37.4%) and health harms (25.4%) of vapes. Males had higher odds of vaping. Use of cigarettes, binge drinking, and cannabis use were associated with vaping. While the co-use of cigarettes with nicotine vapes was observed, this was generally only seen among those who vaped occasionally. A notable knowledge gap existed regarding the legality and awareness of the health harms of vaping, signalling a need for educational initiatives. Future research should continue to monitor emerging vaping trends and long-term outcomes. The project was pre-registered on the Australian New Zealand Clinical Trials Registry (registration number: ACTRN12622000239763).</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"28 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140322542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, Regional, and National Burdens of Major Depressive Disorder and Dysthymia in Adolescents and Young Adults Aged 10–24 Years from 1990 to 2019: A Trend Analysis Based on the Global Burden of Disease Study 2019","authors":"Lina Wang, Dongjun Zhang, Jiali Wu, Minrui Wang, Chenglin Zhang, Jiahan Gao, Haodong Zhao, Dehong Qin","doi":"10.1007/s11469-024-01284-2","DOIUrl":"https://doi.org/10.1007/s11469-024-01284-2","url":null,"abstract":"<p><b>Objective</b> The objective was to assess trends in the burdens of major depressive disorder (MDD) and dysthymia among adolescents and young adults aged 10–24 years from 1990 to 2019 at the global, regional, and national levels. <b>Methods</b> This study was based on average annual percentage changes in the incidence and disability-adjusted life-years (DALYs) for MDD and dysthymia among young people aged 10–24 years. We analyzed global trends by age, sex, and sociodemographic index (SDI). Joinpoint regression was used to analyze global annual change trends. <b>Results</b> Between 1990 and 2019, the incidence of MDD in adolescents and young adults decreased by 0.1% per year, while the incidence of dysthymia increased by 0.2% per year. The greatest increase in the incidence of MDD and dysthymia was observed in the group aged 10–14 years and in the group aged 15–19 years, respectively. The greatest increase in the incidence of and DALYs for MDD was observed in high-SDI countries, while the greatest increase in dysthymia was observed in low-middle-SDI countries. In 2019, the incidence rates of MDD and dysthymia in females were 1.7 times and 1.5 times greater than those in males, respectively. <b>Conclusions</b> Over a 30-year period, the global incidence of MDD in adolescents and young adults did not decrease significantly, and the incidence of dysthymia increased significantly. The results indicate an urgent need for targeted screening for depressive disorders.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"125 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140322522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Media Addiction Predicts Compromised Mental Health as well as Perceived and Objective Social Isolation in Denmark: A Longitudinal Analysis of a Nationwide Survey Linked to Register Data","authors":"Ziggi Ivan Santini, Lau Caspar Thygesen, Susan Andersen, Janne S. Tolstrup, Ai Koyanagi, Line Nielsen, Charlotte Meilstrup, Vibeke Koushede, Ola Ekholm","doi":"10.1007/s11469-024-01283-3","DOIUrl":"https://doi.org/10.1007/s11469-024-01283-3","url":null,"abstract":"<p>Social media addiction has previously been linked to compromised mental health and social isolation; however, most studies are cross-sectional or based on convenience samples. The objective of the current study was to assess the extent to which social media addiction predicts compromised mental health and social isolation (including bi-directionality) in a large prospective sample of Danish adults. Data stem from a nationwide longitudinal Danish survey of 1958 adults (aged 16+) conducted in 2020 and 2021. The Bergen Social Media Addiction Scale (BSMAS) was used. Validated scales were used to assess depression, mental wellbeing, and loneliness. A total of 2.3% screened positive for social media addiction. As compared to no symptoms, social media addiction was associated with an elevated risk for depression (OR = 2.71; 95% CI 1.08, 6.83) and negatively with mental wellbeing (coef = −1.29; 95% CI −2.41, −0.16). Similarly, social media addiction was associated with an elevated risk of loneliness (OR = 4.40; 95% CI 1.20, 16.19), and negatively with social network size (coef = −0.46; 95% CI −0.86, −0.06). There is a need for preventive actions against addictive social media use, as this poses significant risk to mental health and social functioning in the working age population.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"27 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140322447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender Differences in Cannabis Outcomes After Recreational Cannabis Legalization: A United States Repeated Cross-sectional Study, 2008–2017","authors":"Luis E. Segura, Natalie S. Levy, Christine M. Mauro, Emilie Bruzelius, Pia M. Mauro, Sarah Gutkind, Morgan M. Philbin, Deborah S. Hasin, Silvia S. Martins","doi":"10.1007/s11469-024-01271-7","DOIUrl":"https://doi.org/10.1007/s11469-024-01271-7","url":null,"abstract":"<p>Cannabis use has been more prevalent among men than women and prior work has found differing impact of recreational cannabis laws (RCL) by age. We examined changes in the prevalence of past-year and past-month cannabis use, past-month daily cannabis use, and DSM-5-proxy cannabis use disorder (CUD) in the past-year before and after RCL enactment by gender alone and stratified by age using 2008–2017 repeated cross-sectional samples of the US National Survey on Drug Use and Health. Changes in cannabis outcomes were estimated using adjusted multi-level logistic regression with state random intercepts and two-way and three-way interactions between RCL, gender, and age group. Enactment of RCL was associated with higher increases in the past-year (+ 3.2%; aOR = 1.30 [95%CI = 1.19 to 1.41]) and past-month (+ 2.3; 1.37 [1.24 to 1.51]) cannabis use in women than men (+ 2.1%; 1.15 [1.06 to 1.25] and + 1.7%; 1.19 [1.08 to 1.30]). No increases in past-month daily cannabis use and past-year DSM-5 CUD among those using cannabis were observed after RCL enactment. There were no increases in any cannabis outcomes after RCL enactment among those 12–20 years old. RCL enactment may contribute to the narrowing of the cannabis gender gap. Ongoing surveillance is essential to ensure that the social justice aims of legalization are achieved without negative public health consequences.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"76 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140301630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Risk of Adverse Mental Health Events Amongst Users of the National Overdose Response Service (NORS) Telephone Hotline","authors":"","doi":"10.1007/s11469-024-01285-1","DOIUrl":"https://doi.org/10.1007/s11469-024-01285-1","url":null,"abstract":"<h3>Abstract</h3> <p>The National Overdose Response Service (NORS) is a Canadian mobile or virtual overdose response hotline intended to prevent drug overdose deaths but has unexpectedly received mental health related calls, including adverse mental health events. Our study aimed to examine these occurrences and caller characteristics predictive of adverse mental health outcomes. Using the NORS call dataset, we conducted a descriptive representation of mental health occurrences and mental health emergencies along with correlative statistics. We found that NORS had received 2518 mental health calls, with 28 (1.1%) being adverse events. Men, rural callers, polyroute substance consumption and history of overdosing were found to have increased odds of having an adverse mental health event, while being from Quebec, using non-standard consumption routes and using the line between 50 and 99 times were found to decrease odds. This supports the utility of overdose prevention hotlines to also support people experiencing adverse mental health situations and reduce harm for individuals with mental health and/or substance use disorders.</p>","PeriodicalId":14083,"journal":{"name":"International Journal of Mental Health and Addiction","volume":"37 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140301633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}