International Journal of Legal Medicine最新文献_第3页

A fundamental study on postmortem submersion interval estimation by metabolomics analyzing of gastrocnemius muscle from submersed rat models in freshwater. 通过代谢组学分析淡水中沉水大鼠模型的腓肠肌，对死后沉水间隔估计的基础研究。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.1007/s00414-024-03258-4

Fu-Yuan Zhang, Lin-Lin Wang, Kuo Zeng, Wen-Wen Dong, Hui-Ya Yuan, Xing-Yu Ma, Zi-Wei Wang, Yu Zhao, Rui Zhao, Da-Wei Guan

{"title":"A fundamental study on postmortem submersion interval estimation by metabolomics analyzing of gastrocnemius muscle from submersed rat models in freshwater.","authors":"Fu-Yuan Zhang, Lin-Lin Wang, Kuo Zeng, Wen-Wen Dong, Hui-Ya Yuan, Xing-Yu Ma, Zi-Wei Wang, Yu Zhao, Rui Zhao, Da-Wei Guan","doi":"10.1007/s00414-024-03258-4","DOIUrl":"10.1007/s00414-024-03258-4","url":null,"abstract":"In forensic practice, determining the postmortem submersion interval (PMSI) and cause-of-death of cadavers in aquatic ecosystems has always been challenging task. Traditional approaches are not yet able to address these issues effectively and adequately. Our previous study proposed novel models to predict the PMSI and cause-of-death based on metabolites of blood from rats immersed in freshwater. However, with the advance of putrefaction, it is hardly to obtain blood samples beyond 3 days postmortem. To further assess the feasibility of PMSI estimation and drowning diagnosis in the later postmortem phase, gastrocnemius, the more degradation-resistant tissue, was collected from drowned rats and postmortem submersion model in freshwater immediately after death, and at 1 day, 3 days, 5 days, 7 days, and 10 days postmortem respectively. Then the samples were analyzed with liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate the dynamic changes of the metabolites. A total of 924 metabolites were identified. Similar chronological changes of gastrocnemius metabolites were observed in the drowning and postmortem submersion groups. The difference in metabolic profiles between drowning and postmortem submersion groups was only evident in the initial 1 day postmortem, which was faded as the PMSI extension. Nineteen metabolites representing temporally-dynamic patterns were selected as biomarkers for PMSI estimation. A regression model was built based on these biomarkers with random forest algorithm, which yielded a mean absolute error (± SE) of 5.856 (± 1.296) h on validation samples from an independent experiment. These findings added to our knowledge of chronological changes in muscle metabolites from submerged vertebrate remains during decomposition, which provided a new perspective for PMSI estimation.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141156863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motorcycle injuries: a systematic review for forensic evaluation. 摩托车伤：法医评估的系统回顾。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI: 10.1007/s00414-024-03250-y

Elena Giovannini, Simone Santelli, Guido Pelletti, Maria Paola Bonasoni, Elena Lacchè, Susi Pelotti, Paolo Fais

{"title":"Motorcycle injuries: a systematic review for forensic evaluation.","authors":"Elena Giovannini, Simone Santelli, Guido Pelletti, Maria Paola Bonasoni, Elena Lacchè, Susi Pelotti, Paolo Fais","doi":"10.1007/s00414-024-03250-y","DOIUrl":"10.1007/s00414-024-03250-y","url":null,"abstract":"The intricate interplay of exposure and speed leave motorcyclists vulnerable, leading to high mortality rates. During the collision, the driver and the passenger are usually projected away from the motorcycle, with variable trajectories or final positions. Injuries resulting from the crash can exhibit distinct and specific characteristics depending on the circumstances of the occurrence.The aim of this study is to provide a systematic review of the literature on injuries sustained by motorcyclists involved in road accidents describing and analyzing elements that are useful for forensic assessment.The literature search was performed using PubMed, Scopus and Web of Science from January 1970 to June 2023. Eligible studies have investigated issues of interest to forensic medicine about during traffic accidents involving motorcycle. A total of 142 studies met the inclusion criteria and were classified and analyzed based on the anatomical regions of the body affected (head, neck, thoraco-abdominal, pelvis, and limb injuries). Moreover, also the strategies for preventing lesions and assessing injuries in the reconstruction of motorcycle accidents were examined and discussed.This review highlights that, beyond injuries commonly associated with motorcycle accidents, such as head injuries, there are also unique lesions linked to the specific dynamics of accidents. These include factors like the seating position of the passenger or impact with the helmet or motorbike components. The forensic assessment of injury distribution could serve as support in reconstructing the sequence of events leading to the crash and defining the cause of death in trauma fatalities.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141064559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of false starts by saw created on flesh and dry bones; as close as possible to the real conditions of criminal dismemberment. 比较在肉体和枯骨上制造的锯子的虚假启动；尽可能接近犯罪肢解的真实情况。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI: 10.1007/s00414-024-03256-6

Caroline Bernardi, Luísa Nogueira, Nicolas Amoretti, Georges F Carle, Véronique Alunni

{"title":"Comparison of false starts by saw created on flesh and dry bones; as close as possible to the real conditions of criminal dismemberment.","authors":"Caroline Bernardi, Luísa Nogueira, Nicolas Amoretti, Georges F Carle, Véronique Alunni","doi":"10.1007/s00414-024-03256-6","DOIUrl":"10.1007/s00414-024-03256-6","url":null,"abstract":"In most experimental protocols, false starts are produced on dry bones obtained through a maceration process for anthropological analyses, for the sake of reproducibility. Although this allows for controlled experimental conditions, the absence of soft parts when experimentally creating false starts does not correspond to the real conditions of criminal dismemberment. The main objective of this study was to determine if the results of experimental work on the characteristics of false starts were valid under medico-legal conditions. In this experimental study, a hand saw (rip saw, wavy set, TPI 32) was used. 240 false starts were produced on human and pig bones. Randomly, the false starts were either produced on a dry bone or on a flesh bone. The criteria for microscopic analysis included the shape of the walls, the shape and visibility of striae on the floor, the shape of the profile, and the minimum width of the false start. On human bone, 100% of the false starts produced on a bone that had previously undergone a maceration process for anthropological analyses (dry bone) allowed the definition of all the blade characteristics. This was the case for 78.3% on bone in the presence of soft tissue (flesh bone). The striae on the floor of the false start are in some cases less visible with flesh bones, implying that it may be more difficult to conclude on the characteristics of a saw under medico-legal conditions.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141064617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In response to: A critical review of "Artificial intelligence in the practice of forensic medicine: a scoping review". 作为回应：对 "法医学实践中的人工智能：范围审查 "的批判性评论。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-22 DOI: 10.1007/s00414-024-03253-9

Thomas Lefèvre, Laurent Tournois, Bertrand Ludes

引用次数: 0

Detrimental effects of scene manipulations on temperature-based time since death estimation. 场景操作对基于温度的死亡时间估计的不利影响。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-21 DOI: 10.1007/s00414-024-03252-w

Patrick Sauer, Constantin Lux, Hannes Gruber, Marcel A Verhoff, Frank Ramsthaler, Natascha Kern, Mattias Kettner

{"title":"Detrimental effects of scene manipulations on temperature-based time since death estimation.","authors":"Patrick Sauer, Constantin Lux, Hannes Gruber, Marcel A Verhoff, Frank Ramsthaler, Natascha Kern, Mattias Kettner","doi":"10.1007/s00414-024-03252-w","DOIUrl":"10.1007/s00414-024-03252-w","url":null,"abstract":"In forensic casework, time since death (TSD) estimations may play a crucial role to establish chains of events as well as for alibi assessment in homicide cases. Classical TSD estimation relies on reasonably stable ambient temperatures and a correct documentation of ambient and rectal temperatures. This constancy is in some cases disturbed by post-discovery alterations of the crime scene, e.g. opening a window. In order to develop a better understanding of this alteration-based detrimental impact on TSD estimation as well as to identify feasible recommendations for casework, the present pilot study examined ambient temperature effects of different window opening scenarios regarding various time intervals (5 to 360 min) in a furnished 10 m2 apartment during winter. In this context, in addition to the ambient temperature and thus the cooling rate of the room, re-approximation to initial room temperature, potential influences on a nomogram-based time since death estimation using a fictitious case, and the impact of the measurement height above the ground were investigated. Our data indicate a significant reduction of the mean temperature decrease rate after 15 min regardless of the remaining opening time and a correlation with the size of the respective opening surfaces. Re-approximation to initial room temperatures was observed with up to three times longer than the initial opening time. There was no evidence of a substantial advantage of temperature measurements above the level of the corpse (> 0.1 m). The limitations of the study and its applicability for forensic casework are critically reviewed.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141075049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the use of alternative light sources in medico-legal assessments of blunt-force trauma: a systematic review. 在钝器击伤的医学法律评估中使用替代光源的研究：系统性综述。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-06-07 DOI: 10.1007/s00414-024-03262-8

Alexander Tyr, Nina Heldring, Brita Zilg

{"title":"Examining the use of alternative light sources in medico-legal assessments of blunt-force trauma: a systematic review.","authors":"Alexander Tyr, Nina Heldring, Brita Zilg","doi":"10.1007/s00414-024-03262-8","DOIUrl":"10.1007/s00414-024-03262-8","url":null,"abstract":"The ability to analyze blunt-force trauma is crucial for deciphering valuable clues concerning mechanisms of injury and as evidence for medico-legal investigations. The use of alternate light sources (ALS) has been studied over the past decade, and is proposed to outperform conventional white light (CWL) during bruise assessments. In response to the growing interest of the technology worldwide, a systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) to address the ability of ALS to detect and visualize bruising. From an initial 4055 records identified, ten studies met the eligibly criteria and were selected for this review. Evaluation also included a novel framework, referred to as SPICOT, to further systematically assess both scientific evidence and risk of bias in forensic literature. Analysis reveals that narrowband wavelengths within in the infrared or ultraviolet spectral ranges do not significantly outperform CWL in visualizing or detecting bruising. However, wavelengths within the visible spectrum, particularly 415 nm combined with longpass or bandpass yellow filters, are more effective. However, the majority of selected studies only address the sensitivity of ALS, and therefore, results may only be considered valid when the location of a bruise is known. Further investigation is required to understand the specificity of ALS, in particular how the use of topical cosmetic products, previous wounds/scar-tissue, tattoos, moles and freckles may affect detection. The ethical concern regarding the interpretation of enhanced visualized trauma should also be considered in prospect discussions prior to implementing ALS into routine practice. Nevertheless, this review finds that narrowband ALS within the visible spectrum demonstrates potential for improved injury documentation, outperforming CWL in the detection and visualization of bruising.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141283604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bionomics, reproductive traits and assessment of forensic relevance of Peckia (Peckia) chrysostoma (Wiedemann, 1830) (Diptera: Sarcophagidae). Peckia (Peckia) chrysostoma (Wiedemann, 1830) (Diptera: Sarcophagidae)的仿生组学、繁殖特征和法医学相关性评估。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-04-30 DOI: 10.1007/s00414-024-03242-y

Henrique Rafael Pontes Ferreira, Taciano de Moura Barbosa, Simão Dias Vasconcelos

{"title":"Bionomics, reproductive traits and assessment of forensic relevance of Peckia (Peckia) chrysostoma (Wiedemann, 1830) (Diptera: Sarcophagidae).","authors":"Henrique Rafael Pontes Ferreira, Taciano de Moura Barbosa, Simão Dias Vasconcelos","doi":"10.1007/s00414-024-03242-y","DOIUrl":"10.1007/s00414-024-03242-y","url":null,"abstract":"Peckia (Peckia) chrysostoma (Wiedemann, 1830) (Diptera: Sarcophagidae) is a colonizer of cadavers in the Neotropical Region. Nevertheless, data on development for the P. (P.) chrysostoma (e.g., instar duration) and behavioral strategies used by the species for locating and colonizing a corpse are scant. We aimed to explore bionomic and reproductive aspects of the flesh fly P. (P.) chrysostoma, and in this article we: (a) provide quantitative data on the life cycle of P. (P.) chrysostoma; (b) present bionomic measurements (length and weight) of larvae and pupae; (c) describe intrauterine egg and larvae development; and (d) analyze the ovo/larviposition behavior by gravid females. Females showed ovaries with discernible eggs and larvae between 8 and 10 days (x̅ = 23.3 eggs/female). This study reports the first observation of egg deposition, an atypical behavior for the species. The average development time for immature stages was 22.24 h and 21.36 h for 1st and 2nd respectively, and 3rd showed an average development time of 80.47 h. Pupa had the longest duration (x̅ = 295.69 h). A direct increase was observed in weight (P < 0.05) and length (P < 0.05) throughout time. The average survival time of males and females is approximately 30 days. This study expands the knowledge on P. (P.) chrysostoma, such as facultative ovoviviparity under laboratory conditions and the life cycle, which may benefit future studies for accuracy in entomology-based estimation of minimum post-mortem interval (min PMI).","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical localized Mongolian spots in dark pigmented skin - a challenge for forensic medical examination. 深色皮肤局部的非典型蒙古斑--法医检查的难题。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-06-01 DOI: 10.1007/s00414-024-03248-6

Stefanie Schlepper, M Hagen, R Schulz, A Schmeling

引用次数: 0

Forensic age estimation at the University Center of Legal Medicine Lausanne-Geneva: a retrospective study over 12 years. 洛桑-日内瓦法医学大学中心的法医年龄估算：一项历时 12 年的回顾性研究。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-14 DOI: 10.1007/s00414-024-03254-8

Frederique Thicot, Coraline Egger, Claudia Castiglioni, Virginie Magnin, Sana Boudabbous, Nikolaos Angelakopoulos, Silke Grabherr, Pia Genet

{"title":"Forensic age estimation at the University Center of Legal Medicine Lausanne-Geneva: a retrospective study over 12 years.","authors":"Frederique Thicot, Coraline Egger, Claudia Castiglioni, Virginie Magnin, Sana Boudabbous, Nikolaos Angelakopoulos, Silke Grabherr, Pia Genet","doi":"10.1007/s00414-024-03254-8","DOIUrl":"10.1007/s00414-024-03254-8","url":null,"abstract":"With the undeniable increase in asylum requests from unaccompanied alleged minors, age estimation of living individuals has become an essential part of the routine work in European forensic centers. This study aims to review the forensic age estimations performed in our center since 2010, to evaluate the state-of-the-art of this practice in Switzerland with the evolution of the methodology according to upcoming recommendations. Our institute's expert reports performed between 2010 and 2022 were retrospectively analyzed. We gathered the following parameters: demographic data, morphological characteristics, alleged age compared with the assessed minimum age, sexual maturation, dental and bone age. When available, we collected personal and family history, medical history, records of torture-related/self-inflicted injuries, and information about eating habits that might affect skeletal development. Data collection amounted to 656 cases. Forensic age estimations ordered by the Swiss Secretariat for Migration (SEM) represented 76.4% of cases, with 23.6% of them ordered by the Court/Public Prosecutor. Most alleged minors were male (94.5%) and came from Afghanistan (53.4%). Adjunction of CT scans of the sternoclavicular joints was necessary in 86.4% of cases. Only 25.2% of our reports concluded on most probable minority, with 55.6% of definite majors; in 19.2% of our cases, minority could not be excluded. This study aspires to further broaden our expertise regarding forensic age estimations. Given the increasing migratory flows, we can expect a notable increase in the frequency of these requests. Consequently, this study aims to promote a multidisciplinary approach and the international standardization of the methodology of these estimations.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NSPlex: an efficient method to analyze non-specific peaks amplified using commercial STR kits. NSPlex：分析使用商业 STR 试剂盒扩增的非特异性峰的有效方法。

IF 2.2 3区医学

International Journal of Legal Medicine Pub Date : 2024-09-01 Epub Date: 2024-04-13 DOI: 10.1007/s00414-024-03234-y

Yukinobu Kutsuwada, Sho Tomotake, Hidetoshi Tsuda, Kazuhisa Watanabe, Ayumi Matsumoto, Sadahiko Iwamoto, Natsuko Mizuno

{"title":"NSPlex: an efficient method to analyze non-specific peaks amplified using commercial STR kits.","authors":"Yukinobu Kutsuwada, Sho Tomotake, Hidetoshi Tsuda, Kazuhisa Watanabe, Ayumi Matsumoto, Sadahiko Iwamoto, Natsuko Mizuno","doi":"10.1007/s00414-024-03234-y","DOIUrl":"10.1007/s00414-024-03234-y","url":null,"abstract":"Commercial short tandem repeat (STR) kits exclusively contain human-specific primers; however, various non-human organisms with high homology to the STR kit's primer sequences can cause cross-reactivity. Owing to the proprietary nature of the primers in STR kits, the origins and sequences of most non-specific peaks (NSPs) remain unclear. Such NSPs can complicate data interpretation between the casework and reference samples; thus, we developed \"NSPlex\", an efficient method to discover the biological origins of NSPs. We used leftover STR kit amplicons after capillary electrophoresis and performed advanced bioinformatics analyses using next-generation sequencing followed by BLAST nucleotide searches. Using our method, we could successfully identify NSP generated from PCR amplicons of a sample mixture of human DNA and DNA extracted from matcha powder (finely ground powder of green tea leaves and previously known as a potential source of NSP). Our results showed our method is efficient for NSP analysis without the need for the primer information as in commercial STR kits.","PeriodicalId":14071,"journal":{"name":"International Journal of Legal Medicine","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0