{"title":"Comment on: The association between obstructive sleep apnoea and erectile dysfunction: a systematic review and meta-analysis.","authors":"Tao Zhang, Chujie Chen","doi":"10.1038/s41443-026-01349-x","DOIUrl":"https://doi.org/10.1038/s41443-026-01349-x","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gajanan S Bhat, Nandakishore Bhat, Anuradha Shastry
{"title":"Role of afterplay in female sexual satisfaction in heterosexual relationship: A prospective randomized two arm study.","authors":"Gajanan S Bhat, Nandakishore Bhat, Anuradha Shastry","doi":"10.1038/s41443-026-01350-4","DOIUrl":"https://doi.org/10.1038/s41443-026-01350-4","url":null,"abstract":"<p><p>Despite the recognized emotional importance of post-coital intimate behaviors such as hugging, cuddling, talking, kissing, massaging, listening to sensual music, showering, and reading erotic literature (collectively termed afterplay), their impact on female sexual satisfaction has not been systematically studied. This prospective randomized study evaluated the effect of afterplay on sexual satisfaction among sexually active women in heterosexual relationships. Couples with medical comorbidities, psychiatric disorders, or diagnosed sexual dysfunction were excluded. Participants were randomized into two groups using computer-generated random numbers. Both groups received weekly educational sessions on desire, arousal, lubrication, orgasm, satisfaction, pain, and foreplay, with Group B receiving an additional 15-minute session focused on afterplay. Sexual satisfaction was assessed at baseline and after 8 weeks using the Sexual Satisfaction Scale for Women (SSS-W), supplemented by diary-based records of sexual experiences. A total of 431 women completed the study (Group A: 211; Group B: 220), with comparable baseline characteristics. After 8 weeks, Group B showed significantly greater improvement across all SSS-W domains compared with Group A (p ≤ 0.05). These findings identify afterplay as an important factor influencing female sexual satisfaction. Partner education regarding afterplay may represent a simple and effective intervention for improving sexual well-being and addressing female sexual dissatisfaction.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Ventral onlay buccal mucosa graft urethroplasty for female urethral stricture improves female sexual functions.","authors":"Liliana Guadagni, Marco Falcone","doi":"10.1038/s41443-026-01348-y","DOIUrl":"https://doi.org/10.1038/s41443-026-01348-y","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Onder Canguven, Khalid Al Kubaisi, Adnan El-Achkar, Ahmed Ragheb, Orhan Koca, Fernando Nestor Facio, Ege Can Serefoglu
{"title":"Agreement between an anatomy-based inflatable penile prosthesis configuration algorithm and expert surgeon decision-making: a virtual case study.","authors":"Onder Canguven, Khalid Al Kubaisi, Adnan El-Achkar, Ahmed Ragheb, Orhan Koca, Fernando Nestor Facio, Ege Can Serefoglu","doi":"10.1038/s41443-026-01346-0","DOIUrl":"https://doi.org/10.1038/s41443-026-01346-0","url":null,"abstract":"<p><p>Inflatable penile prosthesis configuration remains highly variable among surgeons, with decisions often guided by individual experience rather than standardized criteria. We evaluated agreement between the Canguven Penile Prosthesis Calculator (an anatomy-based decision-support tool) and experienced penile prosthesis surgeons to characterize inter-surgeon variability using a standardized virtual-case model. A total of 60 cases were constructed incorporating total corporal length, proximal corporal length, scrotal size, and predefined prosthesis model (AMS 700 CX™, Boston Scientific Corporation, Marlborough, MA, USA; Titan™, Coloplast Corporation, Minneapolis MN, USA; and Infla10™, Rigicon Inc., Ronkonkoma, NY, USA). A total of 7 experienced penile prosthesis surgeons from 6 institutions independently evaluated the cases, blinded to calculator recommendations, and selected cylinder length, rear-tip extender, and reservoir volume, generating 340 surgeon-case decisions. Agreement was assessed using exact agreement, clinically acceptable agreement (±1 cylinder size), and kappa statistics. Exact agreement between calculator recommendations and surgeon-selected cylinder length was observed in 198 of 340 decisions (58.2%), increasing to 302 of 340 decisions (88.8%) within a clinically acceptable range. The mean absolute difference was 0.95 ± 1.18 cm, with discrepancies greater than 2 cm observed in 38 of 340 decisions (11.2%). Inter-rater agreement was moderate (Fleiss' κ = 0.46, 95% CI 0.41-0.51), and pairwise agreement between the calculator and individual surgeons ranged from κ = 0.43 to 0.55. Reservoir selection demonstrated excellent agreement (329/340 decisions, 96.8%). Variability in prosthesis configuration decisions was primarily driven by differences in rear-tip extender utilization, reflecting consistent but distinct surgeon-specific strategies. Inflatable penile prosthesis configuration demonstrates substantial variability among experienced surgeons, although most differences fall within clinically acceptable limits. The anatomy-based algorithm demonstrated moderate agreement with expert surgeon selections and may provide a structured, anatomy-based framework for prosthesis configuration planning while preserving individualized surgical decision-making.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hector Rodrigo Gonzalez-Carranza, Erick Mauricio Aceves-Rodriguez, Luis Antonio Reyes-Vallejo
{"title":"Latin America's missing voice in sexual medicine: a call to confront an invisible inequity.","authors":"Hector Rodrigo Gonzalez-Carranza, Erick Mauricio Aceves-Rodriguez, Luis Antonio Reyes-Vallejo","doi":"10.1038/s41443-026-01351-3","DOIUrl":"https://doi.org/10.1038/s41443-026-01351-3","url":null,"abstract":"<p><p>Sexual medicine is inseparable from culture, yet the evidence base that guides its practice is generated almost entirely outside many of the regions where much of the world's population lives. A bibliometric review of 9 530 articles published between 2015 and 2025 in eight leading sexual medicine and andrology journals found that only 501 (5.26%) included an author affiliated with a Latin American institution, and that three countries, Brazil, Mexico, and Argentina, accounted for 91.2% of that limited output. Of the twenty countries conventionally classified as Latin America, seven contributed no qualifying article at all and eight more contributed fewer than ten each, so that fifteen of twenty nations were effectively absent from the specialty literature across an eleven-year period. We argue that this is not a peripheral statistical curiosity but a structural failure with direct clinical consequences: guidelines, normative data, and treatment paradigms in sexual medicine are being built on a narrow, culturally specific evidentiary base and then extended to populations that had no part in generating it. Journals, societies, and funders share responsibility for correcting this imbalance, and concrete measures exist to do so.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Massimiliano Raffo, Mirko Preto, Lorenzo Cirigliano, Francesco Montorsi, Andrea Salonia, Paolo Gontero, Marco Falcone
{"title":"Single-stage dorsal-inlay augmented metoidioplasty: technique, complications, and patient-reported outcomes.","authors":"Massimiliano Raffo, Mirko Preto, Lorenzo Cirigliano, Francesco Montorsi, Andrea Salonia, Paolo Gontero, Marco Falcone","doi":"10.1038/s41443-026-01342-4","DOIUrl":"https://doi.org/10.1038/s41443-026-01342-4","url":null,"abstract":"<p><p>Metoidioplasty is a genital gender-affirming surgery that preserves native sensation and erectile capability but remains technically demanding, particularly regarding urethral lengthening. We evaluated perioperative and functional outcomes of a single-stage modified metoidioplasty using dorsal labia minora graft augmentation, ventral anterior vaginal advancement flap reconstruction, and bilateral rotational scrotoplasty incorporating bilateral Martius fat pads. 23 transgender men underwent surgery at a tertiary referral center between 2017 and 2025. Median age was 38 (33-46) years and median follow-up was 36 (24-48) months. Median operative time was 165 (147.5-175) min and hospital stay was 2 (1.5-2.5) days. Early and late complications were observed in 13.0% of patients each. Cumulatively, urethral fistula and urethral stenosis occurred in 17.4 and 8.7% of patients, respectively. 2 (8.7%) fistulas resolved spontaneously, while 17.4% of patients required surgical revision. Patient-reported satisfaction was high, with 95.7% of patients satisfied with surgery and 91.3% reporting satisfaction with micturition and quality-of-life improvement using a non-validated binary questionnaire. This buccal mucosa graft-sparing, tissue-preserving approach appears feasible and safe, with urethral complication rates within the spectrum of outcomes reported in the literature, while potentially simplifying specific reconstructive steps and avoiding donor-site morbidity. Larger prospective comparative studies are warranted.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bailey B Carter, Martin S Gross, Britney L Atwater
{"title":"Comment on: Zero-Touch Technique: a new paradigm in penile prosthesis surgery enabled by a sterile genital barrier system.","authors":"Bailey B Carter, Martin S Gross, Britney L Atwater","doi":"10.1038/s41443-026-01343-3","DOIUrl":"https://doi.org/10.1038/s41443-026-01343-3","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Botulinum toxin a combined with penile traction therapy for the treatment of penile retraction: a retrospective single-arm pilot study.","authors":"Zihao Li, Hailong He, Tao Xu, Xiaowei Zhang","doi":"10.1038/s41443-026-01345-1","DOIUrl":"https://doi.org/10.1038/s41443-026-01345-1","url":null,"abstract":"<p><p>This retrospective single-arm pilot study evaluated a novel minimally invasive approach combining Botulinum Toxin A injection with penile traction therapy for the treatment of penile retraction. This study was conducted in 168 men with retractile penis treated between October 2023 and June 2025. Flaccid penile length was measured in the standing position with the penis in a naturally dependent state after a resting period in a room-temperature environment, using a rigid ruler from the pubic symphysis to the tip of the glans with compression of the suprapubic fat pad. Psychological outcomes were assessed using the Self-Esteem and Relationship questionnaire and the Index of Male Genital Image, while erectile function was evaluated using the five-item International Index of Erectile Function. Mean baseline flaccid penile length was 4.4 ± 0.66 cm, increasing significantly to 6.9 ± 0.81 cm at 6 months (P < 0.001). Improvements were also observed under thermal stimulation and in the penile retraction reduction ratio, which decreased from 27.3-11.6% at 6 months (P < 0.001). Erectile penile length and five-item International Index of Erectile Function scores showed no significant changes. Psychological outcomes improved significantly, with Self-Esteem and Relationship and Index of Male Genital Image scores increasing from 28.8 ± 4.3 and 39.3 ± 5.7-54.4 ± 5.6 and 59.0 ± 7.3, respectively (P < 0.001). Mild transient injection-site pain occurred in 11.3% of patients without other complications. This combined therapy may represent a feasible minimally invasive option for selected patients with penile retraction and reduced visible flaccid penile exposure. However, it does not confer true anatomical penile elongation, and given the exploratory single-arm design, the findings should be interpreted with caution. Further prospective randomized controlled studies using standardized penile measurements and longer follow-up are needed to clarify the durability of treatment effects and the independent contribution of each treatment component.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: SAPOC technique for length restoration in complex Peyronie's disease and erectile dysfunction at the time of penile prosthesis placement.","authors":"Liliana Guadagni, Marco Falcone","doi":"10.1038/s41443-026-01340-6","DOIUrl":"https://doi.org/10.1038/s41443-026-01340-6","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148712359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: soft glans after penile prosthesis surgery: a patient-reported study of prevalence and clinical impact.","authors":"Çağrı Şevik, Gökhan Çeker, Halil Lutfi Canat","doi":"10.1038/s41443-026-01341-5","DOIUrl":"https://doi.org/10.1038/s41443-026-01341-5","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}