International Journal of Medical Physics, Clinical Engineering and Radiation Oncology最新文献

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Measurement of the Energy Spectrum of a 6 MV Linear Accelerator Using Compton Scattering Spectroscopy and Monte Carlo-Generated Corrections 用康普顿散射光谱和蒙特卡罗校正法测量6 MV直线加速器的能谱
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-09-27 DOI: 10.4236/ijmpcero.2020.94017
S. Taneja, L. Bartol, W. Culberson, L. D. Werd
{"title":"Measurement of the Energy Spectrum of a 6 MV Linear Accelerator Using Compton Scattering Spectroscopy and Monte Carlo-Generated Corrections","authors":"S. Taneja, L. Bartol, W. Culberson, L. D. Werd","doi":"10.4236/ijmpcero.2020.94017","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.94017","url":null,"abstract":"Purpose: The energy spectrum of a linear accelerator used for dose calculations is determined during beam commissioning by iteratively adjusting the spectrum and comparing calculated and measured percent depth-dose curves. Direct measurement of the energy spectrum using pulse mode detectors is particularly challenging because of the high-energy, high fluence nature of these beams and limitations of the detector systems. This work implements a Compton scattering (CS) spectroscopy setup and presents detector corrections and spectral unfolding techniques to measure the spectrum of a 6 MV linear accelerator using a pulse mode detector. Methods: Spectral measurements were performed using a Varian Clinac 21EX linear accelerator and a high-purity germanium (HPGe) detector. To reduce fluence to the detector, a custom-built lead shield and a CS spectrometry setup were used. The detector was placed at CS angles of 46°, 89°, and 125°. At each of these locations, a detector response function was generated to account for photon interactions within the experimental geometry. Gold’s deconvolution algorithm was used to unfold the energy spectrum. The measured spectra were compared to simulated spectra, which were obtained using an experimentally benchmarked model of the Clinac 21EX in MCNP6. Results: Measurements were acquired and detector response corrections were calculated for all three CS angles. A comparison of spectra for all CS angles showed good agreement with one another. The spectra for all three angles were averaged and showed good agreement with the MCNP6 simulated spectrum, with all points above 400 keV falling within 4%, which was within the uncertainty of the measurement and statistical uncertainty. Conclusions: The measurement of the energy spectrum of a 6 MV linear accelerator using a pulse-mode detector is presented in this work. For accurate spectrum determination, great care must be taken to optimize the detector setup, determine proper corrections, and to unfold the spectrum.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82872177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Morphological Characteristics of Thymus in the Newborns in Different Climatic and Geographical Conditions of Kyrgyzstan 吉尔吉斯斯坦不同气候地理条件下新生儿胸腺形态特征
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-09-27 DOI: 10.4236/ijmpcero.2020.94016
T. Abaeva, Z. Muratov, R. Tukhvatshin, Zhypargul D. Abdullaeva, A. Seitova, V. Tursunova, Mira Zhanganaeva, M. Satybaldiev, L. Dzhumaeva, Meerim Abduraimova, Feruza Mamasadykova, A. Alimbekova
{"title":"Morphological Characteristics of Thymus in the Newborns in Different Climatic and Geographical Conditions of Kyrgyzstan","authors":"T. Abaeva, Z. Muratov, R. Tukhvatshin, Zhypargul D. Abdullaeva, A. Seitova, V. Tursunova, Mira Zhanganaeva, M. Satybaldiev, L. Dzhumaeva, Meerim Abduraimova, Feruza Mamasadykova, A. Alimbekova","doi":"10.4236/ijmpcero.2020.94016","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.94016","url":null,"abstract":"This paper is describing a detailed study of morphological structures and characteristics newborns thymus in different climatic and geographical conditions of Kara-Balta, Cholpon-Ata, and Bishkek in Kyrgyzstan. Anatomical structure research done on 26 thymuses of newborn corpses. Research results showed that a significant amount of thymuses consisted of lobes with very thin connective tissues between them. It is observed that the Hassall cells were usually located in the medulla part of the thymus after using the coloring by Van-Gieson’s stain visible clear elastic and collagen fibers. In addition, cell population dynamics in a unit of conditional area of cortical substance thymus lobes in newborns determined.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86033192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on Using IMRT Plan for Preoperative Rectal Cancer Patients 直肠癌患者术前应用IMRT方案的研究
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-09-27 DOI: 10.4236/ijmpcero.2020.94015
Q. Vinh, S. Quoc, Cuong Bui Xuan, T. Van, Truong Vu
{"title":"Research on Using IMRT Plan for Preoperative Rectal Cancer Patients","authors":"Q. Vinh, S. Quoc, Cuong Bui Xuan, T. Van, Truong Vu","doi":"10.4236/ijmpcero.2020.94015","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.94015","url":null,"abstract":"Aims: Research the possibility of using IMRT for rectal cancer patients in preoperative radiotherapy. Methods and Material: The research object is the preoperative radiotherapy plan for rectal cancer patients. The research group made two plans (IMRT, 3DCRT) for each image series of 34 rectal cancer patients who have received preoperative radiotherapy in Hanoi Oncology Hospital; and then compared the dose distribution on PTV, bladder, intestine, femoral bones, the average MU, and QA results of two types of plan. Results: The 95% isodose line and 50% isodose of IMRT plan are closer than those of 3DCRT plan. The average dose of PTV in IMRT plan and 3DCRT plan are 5006 ± 23 cGy and 5036 ± 42 cGy, respectively. The HTCI and HI values of IMRT and 3D plan are 0.97 ± 0.026 and 5.37 ± 1.32; 1.00 ± 0.003 and 7.08 ± 0.88. About the dose of organ at risk: The maximum dose, average dose on the right, left femoral head in the IMRT plan are less than those values in the 3DCRT plan (6.2 Gy, 6 Gy, 7.4 Gy, 9 Gy, respectively). The maximum dose and average dose on the bladder of the IMRT plan are smaller than those values of the 3DCRT plan (5.3 Gy, 1.5 times, respectively). The maximum dose and average dose of intestine in the IMRT plan was less than those values in the 3DCRT plan (4.3 Gy, 1.54 times, respectively). The MU number of IMRT plan is 1.5 times bigger than that of 3DCRT plan. Gamma index of IMRT plan is better than that of 3DCRT plan (99% compared with 97%). Conclusions: Using IMRT plan in preoperative radiotherapy for rectal cancer patients can still ensure covered PTV as well as the 3D PLAN. Furthermore, the dose of PTV in the IMRT plan is more uniform than those in the 3D plan, and the dose effect on the OAR surrounding PTV is much lower than when using the 3D plan. When IMRT plan were used to treat the preoperative rectal cancer patients, the LINAC took more time than when using 3DCRT plan.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81515331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Use of a 2-Dimensional Ionization Chamber Array to Measure Head Leakage of a Varian Truebeam® Linear Accelerator 使用二维电离室阵列测量瓦里安Truebeam线性加速器的封头泄漏
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-06-12 DOI: 10.4236/ijmpcero.2020.93009
S. Taneja, J. Teruel, Lei Hu, J. Xue, D. Barbee
{"title":"Use of a 2-Dimensional Ionization Chamber Array to Measure Head Leakage of a Varian Truebeam® Linear Accelerator","authors":"S. Taneja, J. Teruel, Lei Hu, J. Xue, D. Barbee","doi":"10.4236/ijmpcero.2020.93009","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.93009","url":null,"abstract":"The purpose of this work is to evaluate the use of a two-dimensional (2D) planar ion chamber array to characterize leakage radiation from the head of the linear accelerator. Ion chamber arrays provide a benefit over a singular ion chamber measurement as they allow for the measurement of a larger area in order to isolate the point of maximum leakage dose and the small size of each individual ion chamber minimizes volume-averaging effects. A Varian Truebeam® undergoing acceptance testing was used for all measurements. The gantry was wrapped in Portal Pack for Localization (PPL) radiographic film in order to isolate the location of maximum leakage. A calibration curve was developed and used to determine dose-to-film. An Ion Chamber Profiler (IC Profiler™) manufactured by Sun Nuclear Corporation was used to confirm measurements by the PPL film. All measurements were normalized to leakage at 100 cm from the target relative to the central axis. Three points were investigated with the IC Profiler, including the top of the gantry, the Varian logo, and the side of the gantry. For the three locations, respectively, the PPL film and the IC profiler were measured 0.142% and 0.131%, 0.036% and 0.030%, and 0.014% and 0.019%. The good agreement between the PPL film and the IC Profiler provides confidence in the use of a more efficient and accurate ion chamber array for head leakage measurements.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79614443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dosimetric Evaluation of Body Contour Changes to Target Volumes and Organs at Risk for Cervix and Head and Neck Radiotherapy Plans 子宫颈和头颈部放射治疗计划中靶体积和危险器官的身体轮廓变化的剂量学评价
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-06-12 DOI: 10.4236/ijmpcero.2020.93010
Zhe Wu, Jun Yan, Xiaomei Chen, Dong Wang, Ke Liu, Z. Ming, Lin Wang, Bo Yu, Y. Pang
{"title":"Dosimetric Evaluation of Body Contour Changes to Target Volumes and Organs at Risk for Cervix and Head and Neck Radiotherapy Plans","authors":"Zhe Wu, Jun Yan, Xiaomei Chen, Dong Wang, Ke Liu, Z. Ming, Lin Wang, Bo Yu, Y. Pang","doi":"10.4236/ijmpcero.2020.93010","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.93010","url":null,"abstract":"Purpose: To investigate how much dose discrepancy would be caused by the anatomy changes during the radiotherapy (RT) course. Methods: Ten cervical cancer and ten nasopharyngeal carcinoma (NPC) CT datasets from RT patients were enrolled. The body contour from different directions changed to simulate the weight loss or gain for cervical cancer patients, who had been treated with external-beam RT using intensity-modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT). Moreover, the body contour from facial and shoulder superior-inferior positional change had been also assessed for NPC patients using IMRT or VMAT. The new CT (n-CT) was generated by the body contour changes with different directions based on original CT datasets. The dosimetric parameters to target volumes and organs at risk (OARs) were evaluated in Eclipse based on n-CT. Results: The target volumes and OARs were influenced by the body contour changes. Body contour expansion resulted in coverage loss, whereas body contour shrinkage increased the dose to the OARs. These findings were generally consistent for both IMRT and VMAT plans. Over a course of research, the dose to 95% of the target volumes for cervical cancer decreased by up to 2.83% per cm for IMRT and 2.87% per cm for VMAT (P < 0.05). And the influence on H&N plans was that the dose to 95% of the target volumes (low risk regions) decreased by up to 4.45% per cm. Conclusions: The RT staff could determine whether resimulation and replaning or not according to which body contour directions were changed.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90943617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of the Trace Elements Concentrations on the Cancerous and Healthy Tissues in Radiotherapy 放射治疗中微量元素浓度对癌变组织和健康组织的影响
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-06-12 DOI: 10.4236/ijmpcero.2020.93011
T. Sahmaran, A. Kaşkaş
{"title":"The Effect of the Trace Elements Concentrations on the Cancerous and Healthy Tissues in Radiotherapy","authors":"T. Sahmaran, A. Kaşkaş","doi":"10.4236/ijmpcero.2020.93011","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.93011","url":null,"abstract":"The study is aimed to investigate the effect of the trace element concentrations in healthy and cancerous prostate tissues on dose distributions in radiotherapy. In this work, the trace element compounds completely soluble in the water were used and their concentrations given in the literature were mixed homogeneously with pure water. This is the first time study in literature as far as we know. The percent depth dose (PDD) measurements were performed using Elekta Synergy Platform Linac device for 6 and 18 MV photon energies. We also obtained the PDDs results by choosing higher trace element concentrations than given in literature in cancerous prostate tissue to see the effect on radiotherapy. The experimental measurements were compared with the results obtained from the GATE simulation code. The TPR20/10 was calculated for 10 × 10 cm2 field size at 6/18 MV energies photons and compared with simulation results. The differences between simulation and measurement for 6 MV and 18 MV photons are 1.75% and 1.82% respectively. The experimental results and simulations were presented an uncertainty lower than 3%. Simulated dose values are in good agreement with less than 2% differences with the experimental results. We see that the trace element concentrations of healthy and cancerous tissues did not affect the dose distribution at high-energy photons. This is expected and well known result. We believe that this in vitro study is important for proving the reliability of the dose given in radiotherapy treatment once again.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82077468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Complex Target Volume Delineation and Treatment Planning in Radiotherapy for Malignant Pleural Mesothelioma (MPM) 恶性胸膜间皮瘤(MPM)放射治疗的复杂靶体积划定与治疗方案
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-06-12 DOI: 10.4236/ijmpcero.2020.93012
Aaron Innocent Bogmis, Adrian Popa, D. Adam, V. Ciocaltei, N. Guraliuc, F. Ciubotaru, I. Chiricuţă
{"title":"Complex Target Volume Delineation and Treatment Planning in Radiotherapy for Malignant Pleural Mesothelioma (MPM)","authors":"Aaron Innocent Bogmis, Adrian Popa, D. Adam, V. Ciocaltei, N. Guraliuc, F. Ciubotaru, I. Chiricuţă","doi":"10.4236/ijmpcero.2020.93012","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.93012","url":null,"abstract":"Introduction: Radiotherapy alone or combined with surgery and/or chemotherapy is being investigated in the treatment of malignant pleural mesothelioma (MPM). This study aimed to simulate a Volumetric Modulated Arc Therapy (VMAT) treatment of a patient with MPM. Materials and Methods: CT images from a patient with intact lungs were imported via DICOM into the Pinnacle3 treatment planning (TP) system (TPS) and used as a model for MPM to delineate organs at risk (OAR) and both clinical and planning target volumes (CTV and PTV) with a margin of 5 mm. Elekta Synergy with 6 MV photons and 80 leafs MLCi2 was employed. VMAT plans were generated using two coplanar arcs with gantry rotation angles of 178° - 182°, the collimator angles of each arc were set to 90°, Octavius® 4D 729 was employed for quality assurance while the calculated and measured doses were compared using VeriSoft. Results: A TP was achieved. The Gamma volume analysis with criteria of 3 mm distance to agreement and 3% dose difference yielded the gamma passing rate = 99.9%. The reference isodose was 42.75 Gy with the coverage constraints for the PTV D95 and V95 = 95.0% of 45 Gy. The remaining dosimetric parameters met the recommendations from the clinically acceptable guidelines for the radiotherapy of MPM. Conclusion: Using well-defined TV and VMAT, a consistent TP compared to similar ones from publications was achieved. We obtained a high agreement between the 3D dose reconstructed and the dose calculated.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89953371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation Protection of a Patient Undergoing an Orthopedic Procedure by Using a Mobile C-Arm X-Ray System 使用移动c臂x射线系统对骨科手术患者的辐射防护
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-06-12 DOI: 10.4236/ijmpcero.2020.93013
N. Ivanova
{"title":"Radiation Protection of a Patient Undergoing an Orthopedic Procedure by Using a Mobile C-Arm X-Ray System","authors":"N. Ivanova","doi":"10.4236/ijmpcero.2020.93013","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.93013","url":null,"abstract":"Modern medicine is unthinkable without X-rays. Accurate diagnosis, leading to effective treatment, is largely based on precise X-ray examinations. The creation of new, modern equipment and various medical procedures that meet the increased requirements are a priority in our time. X-ray examinations are of particular importance for the orthopedic and traumatological clinics, where they provide information about presence of a fracture in the patient’s body, about the concrete operation performed or about the effect of a suitable treatment. Along with their benefits X-rays have also a harmful effect. This requires special care to protect from this radiation. In this direction, research is constantly being done to improve the quality of radiation protection. Park MR, Lee KM and co-authors, compare the dose load obtained using C-arm and O-arm X-ray systems (which have the capability of combined 2D fluoroscopy and 3D computed tomography imaging). In their study, an orthopedic surgical procedure using C-arm and O-arm systems in 2D fluoroscopy modes was simulated. The radiation doses to susceptible organs of the operators were investigated. He results obtained show that the O-arm system delivered higher doses to the sensitive organs of the operator in all configurations [1]. The article of Stephen Balte briefly reviews the available technologies for measuring or estimation of patient skin dose in the interventional fluoroscopic environment, created by various X-ray equipment including C-arm systems. Given that many patients require multiple procedures, this documentation also aids in the planning of follow up visits [2]. Chong Hing Wong, Yoshihisa Kotani and co-authors evaluate the radiation exposures (RE) to the patient and surgeon during minimally invasive lumbar spine surgery with instrumentation using C-arm image intensifier or O-arm intraoperative CT. The results they get are in favor of the O-arm system [3]. The article “Virtual fluoroscopy for intraoperative C-arm positioning and radiation dose reduction” discusses positioning of an intraoperative C-arm system to achieve clear visualization of a particular anatomical feature by a system for virtual fluoroscopy (called FluoroSim) that could dramatically reduce time and received dose during the procedures. FluoroSim was found to reduce the radiation exposure required for C-arm positioning without reducing positioning time or accuracy, providing a potentially valuable tool to assist surgeons [4]. In our study, we performed practical measurements to show how the patient can be treated by applying most effective radiation protection when using a mobile C-arm X-ray system. For the study, we used exposure upon a phantom placed on the patient’s table. For an X-ray shielding, we used a protective apron with a lead equivalent of 1 mm, placed in two layers on the phantom. In each subsequent series of exposures, the protective apron was placed on the phantom, in a different position relative to the X-ray beam","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79333605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Study of Fast Superposition, Superposition Algorithm in Intensity Modulated Radiotherapy Techniques for Prostate Cancer 前列腺癌调强放疗技术快速叠加、叠加算法的比较研究
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-04-27 DOI: 10.4236/ijmpcero.2020.92007
M. Zope, D. Patil, Angel Kuriakose, P. Aslam, B. George, Abhijeet Mandal
{"title":"Comparative Study of Fast Superposition, Superposition Algorithm in Intensity Modulated Radiotherapy Techniques for Prostate Cancer","authors":"M. Zope, D. Patil, Angel Kuriakose, P. Aslam, B. George, Abhijeet Mandal","doi":"10.4236/ijmpcero.2020.92007","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.92007","url":null,"abstract":"This study aims to compare the dosimetric coverage of the Planning Target Volume (PTV) and the dose to main organs at risk (OARs) between two different algorithms fast superposition (FSUP), superposition (SUP) using intensity-modulated radiotherapy (IMRT) techniques for prostate cancer. Ten patients with prostate cancer were selected for this study. For each patient, IMRT plans were created with 6 MV photon beam quality using CMS XiO treatment planning system. The delivery of IMRT was carried out using the step and shoot techniques. The dose coverage for each patient was designated to an ICRU report 62 reference point in the PTV, medium coverage of the planned target volume to be 95% of the prescribed dose while the maximum dose in the target volume to be not greater than 107% of the prescribed dose. A hypofractionated prescription dose of 70 Gy/28# at 2.5 Gy per fraction was used. Besides we compared the number of MUs and OARs dose to D15%, D25%, D35%, D50% on both algorithm planning sets. For target, this evaluation was made with comparing the conformity index (CI) and homogeneity index (HI). In our study, the results show the OARs got less dose from the SUP algorithm compared to FSUP algorithms. Statistically not significant difference was observed in V107% of PTV, MU/CC, conformity Index (p = 0.057, p = 0.215, p = 0.370) and 95% PTV Volume received prescription dose from both Plans. But Homogeneity Index for both algorithms was statistically significant (p = 0.000, p = 0.001). For prostate cancer, the superposition algorithm showed better results in the IMRT plan compared to the fast superposition algorithm.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73303909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement and Comparison of Output Factors Using Two Detectors for NOVAC7 IntraOperative Radiotherapy Accelerator NOVAC7术中放疗加速器两种探测器输出因子的测量与比较
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-03-25 DOI: 10.4236/ijmpcero.2020.92006
Rafiqul Islam, H. Watabe, A. Stefano
{"title":"Measurement and Comparison of Output Factors Using Two Detectors for NOVAC7 IntraOperative Radiotherapy Accelerator","authors":"Rafiqul Islam, H. Watabe, A. Stefano","doi":"10.4236/ijmpcero.2020.92006","DOIUrl":"https://doi.org/10.4236/ijmpcero.2020.92006","url":null,"abstract":"The aim of this work was to evaluate and compare the performance of comparatively new synthetic PTW 60019 microDiamond with PTW 60017 Diode E detector in measuring the output factors (OF) of IntraOperative Radiation Therapy (IORT) electron beams. For a given electron beam, OFs are defined as the ratio of the dose for any applicator size at the depth of maximum to that for a reference applicator. IORT is an innovative treatment technique that delivers a large single fraction of radiation dose to the tumor bed during surgery. The electron beams considered in this study were generated by the mobile NOVAC7 system. This device produces high-dose-per-pulse electron beams with four different energies in the range from 3 MeV to 9 MeV. We performed measurements for two higher energies, namely 7MeV and 9 MeV. The beam collimation was performed through Perspex (PMMA) cylindrical applicators with different diameters. The accurate dose delivery of IORT tightly depends on the precision of measured dose by reference applicator and the output factors of clinical applicators. The output factors were measured using microDiamond and Diode E detectors. The microDiamond detector performance was compared with a Diode E detector. Determined output factors of two detectors were in good agreement. The maximum deviations of output factors for microDiamond were found 2.74%, and 2.17% for 7 MeV and 9 MeV, respectively with respect to the PTW Diode E. The microDiamond detector was shown to exhibit excellent properties for output factor measurements and could be considered as a suitable tool for electron beam dosimetry.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74955123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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