International Journal of Medical Physics, Clinical Engineering and Radiation Oncology最新文献_第4页

Auto-Segmentation on Liver with U-Net and Pixel De-Convolutional Network 基于U-Net和像素去卷积网络的肝脏自动分割

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-05-18 DOI: 10.4236/IJMPCERO.2021.102008

Huan-Chung Yao, Jenghwa Chang

{"title":"Auto-Segmentation on Liver with U-Net and Pixel De-Convolutional Network","authors":"Huan-Chung Yao, Jenghwa Chang","doi":"10.4236/IJMPCERO.2021.102008","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2021.102008","url":null,"abstract":"Purpose: To improve the liver \u0000auto-segmentation performance of three-dimensional (3D) U-net by replacing \u0000the conventional up-sampling convolution layers with the Pixel De-convolutional \u0000Network (PDN) that considers spatial features. Methods: The U-net was \u0000originally developed to segment neuronal structure with outstanding performance \u0000but suffered serious artifacts from indirectly unrelated adjacent pixels in its \u0000up-sampling layers. The hypothesis of this study was that the segmentation \u0000quality of the liver could be \u0000improved with PDN in which the up-sampling layer was replaced by a pixel \u0000de-convolution layer (PDL). Seventy-eight plans of abdominal cancer patients were \u0000anonymized and exported. Sixty-two were chosen for training two networks: 1) 3D \u0000U-Net, and 2) 3D PDN, by minimizing the Dice loss function. The other sixteen \u0000plans were used to test the performance. The similarity Dice and Average \u0000Hausdorff Distance (AHD) were calculated and compared between these two \u0000networks. Results: The computation time for 62 training cases and 200 \u0000training epochs was about 30 minutes for both networks. The segmentation \u0000performance was evaluated using the remaining 16 cases. For the Dice score, the \u0000mean ± standard deviation were 0.857 ± 0.011 and 0.858 ± 0.015 for the PDN and \u0000U-Net, respectively. For the AHD, the mean ± standard deviation were 1.575 ± \u00000.373 and 1.675 ± 0.769, respectively, corresponding to an improvement of 6.0% \u0000and 51.5% of mean and standard deviation for the PDN. Conclusion: The \u0000PDN has outperformed the U-Net on liver auto-segmentation. The predicted \u0000contours of PDN are more conformal and smoother when compared with the U-Net.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76982764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Considerations and Experience in the Treatment of Lung Cancer with VMAT SBRT + DIBH in Arms-Down Position VMAT SBRT + DIBH俯卧位治疗肺癌的思考与经验

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-05-18 DOI: 10.4236/IJMPCERO.2021.102007

Yulin Song, B. Mueller, Kenneth J. Dow, Z. Saleh, Xiaoli Tang, M. Zinovoy, D. Gelblum, B. Mychalczak

{"title":"Considerations and Experience in the Treatment of Lung Cancer with VMAT SBRT + DIBH in Arms-Down Position","authors":"Yulin Song, B. Mueller, Kenneth J. Dow, Z. Saleh, Xiaoli Tang, M. Zinovoy, D. Gelblum, B. Mychalczak","doi":"10.4236/IJMPCERO.2021.102007","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2021.102007","url":null,"abstract":"The arms-up position \u0000is the most common treatment position adopted for lung cancer patients treated \u0000with radiation therapy. However, many elderly or frail patients have shoulder \u0000problems and cannot tolerate such an overstretched position for an extended \u0000period. Therefore, the arms-down position becomes the only alternative for this \u0000group of patients during radiation therapy. Even though the arms-down position \u0000is not ideal, it does provide a stable and comfortable patient immobilization \u0000position for radiation treatments that require a longer delivery time, such as \u0000stereotactic body radiation therapy (SBRT). In this study, we designed a \u0000protocol to treat lung cancer patients with VMAT stereotactic body radiation \u0000therapy (VMAT SBRT) and deep inspiration breath-hold (DIBH) in the arms-down \u0000position. Our initial clinical experience with this protocol indicates that it \u0000is reliable for patient immobilization and accurate in delivered dosimetry.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75682162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on Clinical Trial NCT00950001 and NCCTG/N107C/CEC.3: Are We Treating Cancer or Water? 临床试验NCT00950001和NCCTG/N107C/CEC点评3 .我们是在治疗癌症还是水?

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-29 DOI: 10.4236/IJMPCERO.2021.101002

Jun-fang Gao

引用次数: 0

Dosimetric Characteristics of 6 MV Medical Linac at BAEC 6 MV医用直线剂在BAEC的剂量学特性

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-29 DOI: 10.4236/IJMPCERO.2021.101004

Sudeb Roy, P. K. Das, R. Khatun, M. A. Rahman, S. Akter, Tushar Kumar, M. M. Ahasan

{"title":"Dosimetric Characteristics of 6 MV Medical Linac at BAEC","authors":"Sudeb Roy, P. K. Das, R. Khatun, M. A. Rahman, S. Akter, Tushar Kumar, M. M. Ahasan","doi":"10.4236/IJMPCERO.2021.101004","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2021.101004","url":null,"abstract":"Dosimetric characteristic is one of the essential parameters of a medical linear accelerator (LINAC), which must be obtained before clinical use. The dosimetric characteristics for 6 MV photon beam were measured and compared with the corresponding published data. The study was done using a Varian linear accelerator (Model Clinac-iX) at the Institute of Nuclear Medical Physics (INMP), AERE, Savar, Dhaka, under the Bangladesh Atomic Energy Commission (BAEC). The data is taken for 10 field sizes (2 × 2, 3 × 3, 5 × 5, 7 × 7, 10 × 10, 15 × 15, 20 × 20, 25 × 25, 30 × 30 and 40 × 40 cm2) at same conditions. The measured Percent Depth Dose (PDD) curves were obtained for 6 MV photon beams with the field as mentioned above and compared with the calculated PDD curves. The measured depth dose (Dmax) for reference field size (FS) 10 × 10 cm2 is 15.99 mm, and the PDD at 10 cm depth (D10) is 66.87% for 6 MV photon energies that are found to be compatible with the published report BJR supplement 25. The measured PDD curves for photon energies show a good agreement with the standard PDD curves. The photon beam dosimetry data found in the current study are compatible and all the tolerances are within the clinically acceptable tolerance limit.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"5 1","pages":"38-46"},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78909020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commissioning of the TrueBeam STx 6 MV FFF Beam in the RayStation Treatment Planning System for SRS and SBRT Treatments 在用于SRS和SBRT治疗的RayStation治疗计划系统中调试TrueBeam STx 6 MV FFF光束

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-29 DOI: 10.4236/IJMPCERO.2021.101003

Yongsook C. Lee, Yongbok Kim

{"title":"Commissioning of the TrueBeam STx 6 MV FFF Beam in the RayStation Treatment Planning System for SRS and SBRT Treatments","authors":"Yongsook C. Lee, Yongbok Kim","doi":"10.4236/IJMPCERO.2021.101003","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2021.101003","url":null,"abstract":"Purpose: The purpose of this study is to provide technical information on commissioning the TrueBeam STx 6 MV flattening-filter free (FFF) beam in the RayStation treatment planning system (TPS) for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments. Methods: For beam modeling, percent depth dose curves, profiles and output factors for jaw-collimated fields and stereotactic cones as well as X-jaws transmission were measured. For multi-leaf collimator (MLC) modeling, MLC model parameters such as offset, gain, curvature, leaf tip width, tongue and groove and transmission were determined and output factors for MLC-collimated fields were measured. Absolute dose calibration was also performed. For beam model and MLC model validation, the American Association of Physicists in Medicine Task Group-119 plans, clinical SRS and SBRT plans and end-to-end testing were performed. Results: Beam characteristics of the 6 MV FFF beam agreed well with those in the literature. Validation results showed that our beam model and MLC model were acceptable for SRS and SBRT treatments. Conclusions: The technical information and dosimetric data provided in this study will be a useful reference for other clinics/institutions which will commission the same machine energy in the RayStation TPS.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89590101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Intensity Modulated Proton Therapy for Re-Irradiation of Bulky Loco-Regional Recurrent Breast Cancer: A Case Report 调强质子治疗再照射大体积局部区域复发乳腺癌1例

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-29 DOI: 10.4236/IJMPCERO.2021.101001

Bosco Giap, Thorsten Ostrander, Angela Waldinger, F. Giap, H. Giap

{"title":"Intensity Modulated Proton Therapy for Re-Irradiation of Bulky Loco-Regional Recurrent Breast Cancer: A Case Report","authors":"Bosco Giap, Thorsten Ostrander, Angela Waldinger, F. Giap, H. Giap","doi":"10.4236/IJMPCERO.2021.101001","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2021.101001","url":null,"abstract":"Patients with recurrent breast cancer to chest wall, who had previous irradiation, are difficult to manage and have limited options. Several reports described the use of photon therapy, hyperthermia, and brachytherapy. This is a case report of a 72-year-old female with Stage IIIA (pT3N1M0) invasive ductal carcinoma of the right breast status post modified radical mastectomy. The patient developed recurrence to the chest wall and one internal mammary lymph node one year later. She received 3-D conformal photon radiation therapy for this recurrence. Two years later, she had progression of the recurrence at the right chest wall and axillary and internal mammary lymph nodes. She was treated with intensity modulated proton therapy (IMPT) for a total of 6600 cGy in 33 fractions. However, four months later, she was found to have biopsy-proven isolated metastatic disease at her right bicep, which was again treated with IMPT for a dose of 6000 cGy in 20 fractions. Proton beam therapy was used in this case to spare dose to the brachial plexus, heart and lung while optimally irradiating the recurrent tumors. At last follow up, the patient is alive and has been disease free for 39 months. This report describes the technique and dosimetry for this unique case, which also reviewed recent series of re-irradiation using proton beam.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"1 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82326052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated Linac QA Using Scripting and Varian Developer Mode 使用脚本和瓦里安开发模式自动直线测试

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-01 DOI: 10.4236/ijmpcero.2021.104013

K. Pearman, Nicholas Koch, D. Wiant, Han Liu, B. Sintay

{"title":"Automated Linac QA Using Scripting and Varian Developer Mode","authors":"K. Pearman, Nicholas Koch, D. Wiant, Han Liu, B. Sintay","doi":"10.4236/ijmpcero.2021.104013","DOIUrl":"https://doi.org/10.4236/ijmpcero.2021.104013","url":null,"abstract":"Purpose: Linac quality assurance (QA) can be time consuming involving set up, execution, analysis and subject to user variability. The purpose of this study is to develop qualitative automation tools for mechanical and imaging QA to improve efficiency, consistency, and accuracy. Methods and Materials: Traditionally QA has been performed with graph paper, film, and multiple phantoms. Analysis consists of ruler and vendor provided software. We have developed a single four-phantom method for QA procedures including light-radiation coincidence, imaging quality, table motion and Isocentricity and separately cone beam computed tomography. XML scripts were developed to execute a series of tasks using Varian’s Truebeam Developer Mode. Non-phantom QA procedures have also been developed including field size, dose rate, MLC position, MLC and gantry speed, star shot, Winston-Lutz and Half Beam Block. All analysis is performed using inhouse MATLAB codes. Results: Overall time savings were 2.2 hours per Linac per month. Consistency improvements (standard deviation, STD) were observed for some tests. For example: field size improved from 0.11 mm to 0.04 mm and table motion improved from 0.17 mm to 0.12 mm. CBCT STD improved from 0.99 mm to 0.61 mm for slice thickness. No STD change was observed for Isocentricity test. We noticed an increase in STD from 0.33 mm to 0.41 mm for light-radiation coincidence test. There was a small drop in field size accuracy. Isocentricity showed an increase in measurement accuracy from 0.47 mm to 0.15 mm. Table motion increased in accuracy from 0.20 mm to 0.16 mm. Conclusion: Automation is a viable, accurate and efficient option for monthly and annual QA.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83612111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Studies of Absolute Dose in Water Phantom, Solid Water Phantom and MatriXX with MULTICube Phantom 水幻影、固体水幻影和MatriXX多管体幻影绝对剂量的比较研究

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-01 DOI: 10.4236/ijmpcero.2021.104014

Tusher Kumer, P. K. Das, R. Khatun, Md. Ashikur Rahman, Shirin Akter, S. K. Roy

引用次数: 2

A Novel Technique to Validate Dosimetry for Single-Isocenter Multiple-Target VMAT Stereotactic Radiosurgery 一种验证单等中心多靶点VMAT立体定向放射手术剂量学的新技术

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2021-01-01 DOI: 10.4236/IJMPCERO.2021.102006

Yulin Song, Miao Zhang, L. Voros, Xiaoli Tang, Z. Saleh, W. Cai, J. Jeong, B. Mueller, B. Mychalczak

引用次数: 1

The Evaluation of Efficacy and Side Effects of Radiotherapy in Cerebral Meningiomas 脑膜瘤放射治疗的疗效及副作用评价

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Pub Date : 2020-09-27 DOI: 10.4236/IJMPCERO.2020.94014

T. Koca, R. Aksoy, Y. Şengün, M. Aksu, N. Tunçel, Mine Genc Ozay, A. F. Korcum

{"title":"The Evaluation of Efficacy and Side Effects of Radiotherapy in Cerebral Meningiomas","authors":"T. Koca, R. Aksoy, Y. Şengün, M. Aksu, N. Tunçel, Mine Genc Ozay, A. F. Korcum","doi":"10.4236/IJMPCERO.2020.94014","DOIUrl":"https://doi.org/10.4236/IJMPCERO.2020.94014","url":null,"abstract":"Aims: The current study aimed to evaluate the efficacy, side effects of radiotherapy and factors influencing treatment outcome in patients received radiotherapy for cerebral meningiomas. Methods and Material: In the last two decades, a total of 35 patients with cerebral meningioma who received radiotherapy in our clinic were evaluated statistically in terms of survival, toxicity and prognostic factors. The records of patients diagnosed with cerebral meningioma who underwent postoperative radiotherapy were retrospectively analyzed. Statistical analysis used: Statistical comparisons were made using IBM SPSS v24.0. Kaplan-Meier method was used to compare survival times. Results: Five of the patients had grade I meningioma showing recurrence, 18 were grade II meningioma and 12 were grade III meningioma. Patients were treated with 54 or 60 Gy adjuvant radiotherapy with 2 Gy daily fractions according to histopathological grade and operation type. Three and five-year overall survival rates were 56% and 40%, respectively and median overall survival was 36 months. Progression was observed in 15 of the 35 patients included in the study. Three and five-year progression-free survival (PFS) rates of the patients were 56% and 50%, respectively. There was a statistically significant correlation between histopathological grade and overall survival among patients. However; no statistical difference found in overall survival of patients in terms of tumor location, operation type and age. Conclusions: In the treatment of cerebral meningiomas, changes in radiotherapy dose and field designs can be predicted according to the tumor grade and operation type. In addition, it is thought that large scale studies are needed to determine prognostic factors more meticulously.","PeriodicalId":14028,"journal":{"name":"International Journal of Medical Physics, Clinical Engineering and Radiation Oncology","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84818523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0