International journal of medicinal mushrooms最新文献_第2页

Morphology of four strains of Medicinl phellinoid Agaricomycetes, and microstructural and physiological properties of their exudates 四株黄皮姬松茸的形态及其渗出物的微观结构和生理特性

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-06-01 DOI: 10.1615/intjmedmushrooms.2024054258

Dong Yating, Lina Guo, Haile Ma, Muhammad Tayyab Rashid, Jamila Akter Tuly, GOLLY, K. Moses, Cunshan Zhou, ronghai He, xiaofei Ye, bingcheng Gan, xing Han

{"title":"Morphology of four strains of Medicinl phellinoid Agaricomycetes, and microstructural and physiological properties of their exudates","authors":"Dong Yating, Lina Guo, Haile Ma, Muhammad Tayyab Rashid, Jamila Akter Tuly, GOLLY, K. Moses, Cunshan Zhou, ronghai He, xiaofei Ye, bingcheng Gan, xing Han","doi":"10.1615/intjmedmushrooms.2024054258","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024054258","url":null,"abstract":"To study and compare the morphology of the phellinoid Agaricomycetes strains and find other strategies to improve Phellinus spp. growth and metabolism. In this study, the morphological characteristics of four Phellinus igniarius strains (phellinoid Agaricomycetes) were observed under a light microscope. The exudates from these fungi were observed using light microscopy, scanning electron microscopy (SEM), and energy-dispersive spectrometry (EDS). The exudates were initially transparent with a water-like appearance, and became darker with time at neutral pH. Microscopy of air-dried exudates revealed regular shapes and crystals. Cl-(chloride) and K+ were the two key elements analyzed using EDS. Polyphenol oxidase (POD), catalase (CAT), and laccase activities were detected in mycelia from each of the four Phellinus strains. The K+ content of the three strains was higher than that of the wild strain. Cl- content correlated negatively with that of K+. Laccase activities associated with each mycelia and its corresponding media differed under cold and contaminated conditions.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"10 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141196663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antifungal and Antibacterial Activities of Crude Extracts of Four Phellinus species and Coltricia fragilissima (Agaricomycetes) from Cameroon and Democratic Republic of Congo 喀麦隆和刚果民主共和国四种黄柏属植物和 Coltricia fragilissima（姬松属）粗提物的抗真菌和抗细菌活性

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-06-01 DOI: 10.1615/intjmedmushrooms.2024054634

MOSSEBO Dominique Claude, Blondo-Pascal Metsebing, Romuald Oba, Fabrice Tsigaing Tsigain, Thierry Fonkui Youmbi, Marthe Carine Djuidje Fosting, Tata Charlotte Mungoh, Derek Ntantoh Ndinteh

{"title":"Antifungal and Antibacterial Activities of Crude Extracts of Four Phellinus species and Coltricia fragilissima (Agaricomycetes) from Cameroon and Democratic Republic of Congo","authors":"MOSSEBO Dominique Claude, Blondo-Pascal Metsebing, Romuald Oba, Fabrice Tsigaing Tsigain, Thierry Fonkui Youmbi, Marthe Carine Djuidje Fosting, Tata Charlotte Mungoh, Derek Ntantoh Ndinteh","doi":"10.1615/intjmedmushrooms.2024054634","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024054634","url":null,"abstract":"Antifungal and antibacterial activities of crude extracts of Phellinus extensus, Ph. gilvus, Ph. pachyphloeus, Ph. senex and Coltricia fragilissima were investigated on eleven species of bacteria and three fungal human pathogens. The minimum inhibitory concentration (MIC) was determined by the microdilution method. The results of this study reveal that for the eleven strains of bacteria tested, including Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, S. epidermidis, Enterobacter cloacae, Klebsiella aerogenes, Mycobacterium smegmatis, Proteus vulgaris, Proteus mirabilis and Escherichia choli, the MIC of the crude extract of the four species of Phellinus as well as that of C. fragilissima ranged from 3.13 to 12.50 mg/mL. For the three strains of fungi tested including Candida albicans, Aspergillus ochraceus and A. fumigetus, the MIC of the crude extracts of the same four species of Phellinus as well as that of C. fragilissima ranged from 0.39 to 3.13 mg/mL. These data reveal that the antimicrobial activity of crude extracts of Phellinus and Coltricia species is stronger on pathogenic fungi than on bacteria. C. fragilissima being of the same family as Phellinus and having recorded the values of MIC eminently close to those of the latter may potentially be used for medicinal purposes like the investigated Phellinus species. Being highly represented in the sub-Saharan regions and owing to the above-mentioned results, these species could now be considered as part of the non-exhaustive list of medicinal mushrooms in these regions and may constitute a new source of natural molecules that may be more active than synthetic products against certain fungal and bacte","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"24 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141528962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Addition of Mucoadhesive Agent to Enzymatically Polymerized Caffeic Acid-Based Nasal Vaccine Formulation Attenuates Antigen-Specific Antibody Responses in Mice 在基于咖啡酸的酶法聚合鼻腔疫苗制剂中添加黏附剂可减轻小鼠的抗原特异性抗体反应

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-06-01 DOI: 10.1615/intjmedmushrooms.2024054586

Rui Tada, Hiroki Ito, Yuzuho Nagai, Yasuhiro Sakurai, Daisuke Yamanaka, Naohito Ohno, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi

{"title":"Addition of Mucoadhesive Agent to Enzymatically Polymerized Caffeic Acid-Based Nasal Vaccine Formulation Attenuates Antigen-Specific Antibody Responses in Mice","authors":"Rui Tada, Hiroki Ito, Yuzuho Nagai, Yasuhiro Sakurai, Daisuke Yamanaka, Naohito Ohno, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi","doi":"10.1615/intjmedmushrooms.2024054586","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024054586","url":null,"abstract":"Mucosal vaccination is a promising strategy for combating infectious diseases caused by pathogenic microbes, as it can generate antigen-specific immune responses in both systemic and mucosal compartments. In our recent study, we developed a nasal vaccine system for Streptococcus pneumoniae infections in mice using enzymatically polymerized polyphenols such as caffeic acid. However, the efficacy of this mucosal vaccine system is approximately 70%, indicating a need for improvement. To address this issue, we hypothesized that incorporating a mucoadhesive agent that enhances mucosal absorption into a polyphenol-based mucosal vaccine system would improve vaccine efficacy. Contrary to our expectations, we found that adding a mucoadhesive agent, hydrophobically modified hydroxypropylmethylcellulose (HM-HPMC), to the vaccine system reduced the stimulation of antigen-specific antibody responses in both the mucosal (more than 90% reduction; p < 0.05) and systemic compartments (more than 80% reduction; p < 0.05). Although the addition of the mucoadhesive agent may have interfered with the interaction between the mucosal epithelium and the vaccine system, the underlying mechanism remains unclear, and further research is needed to fully understand the mechanisms involved.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"57 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141513382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Diversity and Ethno-Mycopharmacological Insights of Medicinal Mushrooms of Bangus Valley of Jammu and Kashmir (India) 印度查谟和克什米尔邦古斯山谷药用蘑菇的多样性和民族菌药学见解

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-06-01 DOI: 10.1615/intjmedmushrooms.2024054174

Shoaib Ahmad Lone, Abdul Hamid Wani, MOHD YAQUB BHAT, Prince Firdoos Iqbal

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Medicinal Potential of the Giant Puffball Mushroom Calvatia gigantea (Agaricomycetes): A Review 巨型袖珍蘑菇 Calvatia gigantea（姬松茸科）的药用潜力：综述

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024054161

Małgorzata Cicha-Jeleń, Bożena Muszyńska, Katarzyna Kała, Katarzyna Sułkowska-Ziaja

引用次数: 0

Oral administration of Ganoderma lucidum extract protects gingival tissues against proinflammatory TNF and oxidative stress in periodontitis model rats 口服灵芝提取物可保护牙周炎模型大鼠的牙龈组织免受促炎性 TNF 和氧化应激的影响

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024053946

Shahdat Hossain, Mohammad Azizur Rahman, Borhan Uddin, Taslima Nahar, Marzan Sarker, Shoriful Islam Joy

{"title":"Oral administration of Ganoderma lucidum extract protects gingival tissues against proinflammatory TNF and oxidative stress in periodontitis model rats","authors":"Shahdat Hossain, Mohammad Azizur Rahman, Borhan Uddin, Taslima Nahar, Marzan Sarker, Shoriful Islam Joy","doi":"10.1615/intjmedmushrooms.2024053946","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024053946","url":null,"abstract":"Ganoderma lucidum is a medicinal mushroom that has been tempting since ancient times. We investigated whether chronic oral administration of G. lucidum extract withstands the increases in levels of proinflammatory TNF and lipid peroxide (LPO), an indicator of oxidative stress, in gingival tissue of periodontitis model rats. It was also investigated if G. lucidum extract inhibits oxidative stress induced by Fenton’s reagents in whole homogenates of fresh rat gigival tissues in vitro. Prior to in vivo and in vitro experiments with rats, G. lucidum extract was quantitatively tested for its total polyphenols and/or flavonoids content and ability to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH)-free radicals. Chronic oral administration of G. lucidum extract (300 mg/kg BW, body weight) significantly reduced TNF and LPO levels in the gingival tissue of periodontitis model rats. G. lucidum extract also inhibited oxidative stress in vitro (P<0.05), as indicated by reduced LPO levels in gingival tissue whole homogenates preincubated with G. lucidum extract. The in vitro results were thus consistent with those in vivo inhibition of lipid peroxidation, DPPH free radical-scavenging effect and the presence of total polyphenols/flavonoids in G. lucidum extract. Our results provide, at least partial evidence for the beneficial effect of G. lucidum on periodontitis, an inflammatory disease of the gums associated with oxidative stress and preceding infectious gum disease.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"157 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140932605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The Analysis of Chemical and Medicinal Properties of Armillaria Ostoyae (Agaricomycetes) Extracts and the Presence of Heavy Metals in Dry Basidiocarps 姬松茸提取物的化学和药用特性及干基木中重金属含量的分析

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024054187

Nevena Petrovic, Tomislav Tosti, Ivana Srbljak, Ana Đurić, Zoran Simić, Marijana Kosanic

{"title":"The Analysis of Chemical and Medicinal Properties of Armillaria Ostoyae (Agaricomycetes) Extracts and the Presence of Heavy Metals in Dry Basidiocarps","authors":"Nevena Petrovic, Tomislav Tosti, Ivana Srbljak, Ana Đurić, Zoran Simić, Marijana Kosanic","doi":"10.1615/intjmedmushrooms.2024054187","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024054187","url":null,"abstract":"In this manuscript, we investigated the chemical and medicinal properties of methanolic and acetonic extracts of Armillaria ostoyae and the presence of heavy metals in its dry basidiocarps. The chemical content of extracts was analyzed with the HPLC-DAD-MS/MS method. According to our results, the most abundant mineral was potassium; the most abundant organic acid was malic acid; the most abundant carbohydrate was fructose, and the most abundant polyphenol was chlorogenic acid. The antimicrobial potential was evaluated using the microdilution assay, and the results ranged from 0.62 to 20 mg/mL. Antioxidant potential was studied by DPPH (IC50 of the methanolic extract was 619.67 μg/mL and of the acetonic extract was 533.65 μg/mL) and reducing power assays (the results ranged 0.025-0.078 μg/mL). Total phenolic content was presented as gallic acid equivalent (methanolic extract - 6.12 mg GAE/g; acetonic extract – 3.99 mg GAE/g). The antidiabetic potential was explored by applying the α-amylase (the results ranged from 39.62 to 44.33%) and α-glucosidase assays (the results were in the range of 0.27–2.51%). The neuroprotective activity was asserted by the acetylcholinesterase inhibition assay (the results were in the range of 3.06-6.09%). The cytotoxic potential was investigated using the microtetrazolium assay, and the IC50 values ranged from 221.96 to > 400 μg/mL. Heavy metal content of the dry basidiocarps was evaluated using the AAS method and iron was the most abundant metal. Armillaria ostoyae is a conditionally edible mushroom, which was not studied thoroughly before, thus this research will provide valuable knowledge about this species.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"10 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141147757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Enhancing Cordycepin in Functional Porridge through Rice Varietal Fermentation with Cordyceps militaris (Ascomycetes) and Utilizing Non-Targeted Metabolomics for Process Enhancement 通过冬虫夏草（子囊菌）与水稻品种发酵及利用非靶向代谢组学改进工艺，提高功能粥中的虫草素含量

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024054150

Min-Ling Liu, Tsu-Yi Chien, Hui-Chen Lo, Tai-Hao Hsu, Shih-Chieh Lee, Shih-Ching Chao

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In vitro assessment of 4-acetyl-antrquinonol B and erinacine A in suppressing breast cancer-induced osteoclastogenesis 4-acetyl-antrquinonol B 和麦角新碱 A 在抑制乳腺癌诱导的破骨细胞生成方面的体外评估

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024053977

Yi-Ming Huang, You-Sheng Fu, Woan-Ling Chen, Hsi-Chi Lu

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The Artist's Conk Medicinal Mushroom Ganoderma applanatum (Agaricomycetes): A Mycological, Mycochemical, and Pharmacological Values: A Review 艺术家的海螺药用蘑菇灵芝（姬松茸）：真菌学、真菌化学和药理学价值：综述

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2024-05-01 DOI: 10.1615/intjmedmushrooms.2024053900

Mengtao Cheng, Liying Zhang, Jing Wang, Xiaomei Sun, Yitong Qi, Lijing Chen, chunchao han

{"title":"The Artist's Conk Medicinal Mushroom Ganoderma applanatum (Agaricomycetes): A Mycological, Mycochemical, and Pharmacological Values: A Review","authors":"Mengtao Cheng, Liying Zhang, Jing Wang, Xiaomei Sun, Yitong Qi, Lijing Chen, chunchao han","doi":"10.1615/intjmedmushrooms.2024053900","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2024053900","url":null,"abstract":"As a commonly used Chinese herbal medicine, Ganoderma applanatum (Pers.) Pat., also known as flatling Ganoderma (Chinese name Bianlingzhi), old mother fungus (Laomujun) and old ox liver (Laoniugan), has high medicinal value. It is used as an anti-cancer drug in China and Japan. Besides, it can treat rheumatic tuberculosis and has the effect of relieving pain, clearing away heat, eliminating accumulation, stopping bleeding and eliminating phlegm. The purpose of this review is to systematically and comprehensively analyze the research progress in mycology, mycochemistry and pharmacological activities of G. applanatum, and discuss the prospect of prospective research and implementation of this medicinal material. A comprehensive literature search was performed on G. applanatum using scientific databases including Web of Science, PubMed, Google Scholar, CNKI, Elsevier. Collected data from different sources was comprehensively summarized for mycology, mycochemistry and pharmacology of G. applanatum. A total of 324 compounds were recorded, the main components of which were triterpenoids, meroterpenoids, steroids, and polysaccharides. G. applanatum and its active ingredients have a variety of pharmacological effects, including anti-tumor, liver protection, hypoglycemic, anti-fat, anti-oxidation, antibacterial and other activities. Although G. applanatum is widely used in traditional medicine and has diverse chemical constituents, more studies should be carried out in animals and humans to evaluate the cellular and molecular mechanisms involved in its biological activity.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"11 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140941883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0