International journal of medicinal mushrooms最新文献_第10页

Antioxidant and Antimicrobial Properties of Fruiting Body and Submerged Mycelium of Medicinal Mushroom Phellinus robiniae (Agaricomycetes). 药用蘑菇菲利菌子实体和沉水菌丝的抗氧化和抗菌特性

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022047243

Tuan Manh Nguyen, Jaisoo Kim, Nguyen The Hung, Nguyen Huu Tho, Do Bich Due, Do Thi Hien

{"title":"Antioxidant and Antimicrobial Properties of Fruiting Body and Submerged Mycelium of Medicinal Mushroom Phellinus robiniae (Agaricomycetes).","authors":"Tuan Manh Nguyen, Jaisoo Kim, Nguyen The Hung, Nguyen Huu Tho, Do Bich Due, Do Thi Hien","doi":"10.1615/IntJMedMushrooms.2022047243","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022047243","url":null,"abstract":"This study was conducted to evaluate extraction yield, antioxidant content, antioxidant capacity and antibacterial activity of extracts obtained from submerged mycelium (ME) and fruiting body (FBE) of Phellinus robiniae NTH-PR1. The results showed that yields of ME and FBE reached 14.84 ± 0.63 and 18.89 ± 0.86%, respectively. TPSC, TPC, and TFC were present in both mycelium and fruiting body, and the more contents of them were found in fruiting body. The concentrations of TPSC, TPC and TFC in ME and FBE were 17.61 ± 0.67 and 21.56 ± 0.89 mg GE g-1, 9.31 ± 0.45 and 12.14 ± 0.56 mg QAE g-1, and 8.91 ± 0.53 and 9.04 ± 0.74 mg QE g-1, respectively. EC50 values for DPPH radical scavenging revealed FBE (260.62 ± 3.33 μg mL-1) was more effective than ME (298.21 ± 3.61 μg mL-1). EC50 values for ferrous ion chelating in ME and FBE were 411.87 ± 7.27 and 432.39 ± 2.23 μg mL-1, respectively. Thus, both extracts were able to inhibit Gram-positive and Gram-negative pathogenic bacterial strains, at concentrations ranging in 25-100 mg mL-1 of ME and 18.75-75 mg mL-1 of FBE for Gram-positive bacteria; ranging in 75-100 mg mL-1 of ME and 50-75 of FBE for Gram-negative bacteria. Overall submerged mycelial biomass and fruiting bodies of Ph. robiniae NTH-PR1 can be considered as useful natural sources for development of functional food, pharmaceuticals and cosmetic products or cosmeceuticals.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 3","pages":"37-46"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9257110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Potentiation of Antitumor Activity by Antibody Drugs and Mushroom-Derived β-Glucans in Natural Killer Cell-Mediated Tumoricidal Activities against Non-Hodgkin's B-Cell Lymphoma. 抗体药物和蘑菇源β-葡聚糖增强自然杀伤细胞介导的非霍奇金b细胞淋巴瘤的抗肿瘤活性。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022047219

Yoshiyuki Adachi, Fumiyasu Momose, Hiromi Momose, Rui Tada, Naohito Ohno

{"title":"Potentiation of Antitumor Activity by Antibody Drugs and Mushroom-Derived β-Glucans in Natural Killer Cell-Mediated Tumoricidal Activities against Non-Hodgkin's B-Cell Lymphoma.","authors":"Yoshiyuki Adachi, Fumiyasu Momose, Hiromi Momose, Rui Tada, Naohito Ohno","doi":"10.1615/IntJMedMushrooms.2022047219","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022047219","url":null,"abstract":"β-glucans are polysaccharides that activate innate immunity. We herein investigated whether P-glucans promote the immunological effects of antibody drugs against malignant tumor cells using human peripheral blood mononuclear cells (PBMCs). Rituximab bound to CD20-specific lymphoma and exhibited cytotoxic activity in the presence of human mononuclear cells, but not neutrophils. The addition of Sparassis crispa (cauliflower mushroom)-derived β-glucan (SCG) and granulocyte macrophage colony-stimulating factor (GM-CSF) to co-cultures of PBMCs and Raji lymphoma cells further promoted antibody-dependent cell-mediated cytotoxicity (ADCC). The GM-CSF treatment increased β-glucan receptor expression on adherent cells in PBMCs. A co-stimulation with GM-CSF and SCG of PBMCs induced an increase in the number of spreading cells and the activation of natural killer (NK) cells. The enhancement in ADCC was abolished by the removal of NK cells, indicating that SCG and GM-CSF increased ADCC against lymphoma by activating β-glucan receptor-expressing cells in PBMCs and enhancing NK cell activity. The synergistic mechanisms of action of mushroom-derived β-glucans and biopharmaceuticals, including recombinant cytokines and antibodies, in the treatment of malignant tumor cells provide important insights into the clinical efficacy of β-glucans from mushrooms.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 3","pages":"1-19"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9257112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactivity Profiling of Infusion, Decoction, and Hydroalcoholic Fraction Obtained from Wild Golden Chanterelle Mushroom, Cantharellus cibarius (Agaricomycetes). 野生金鸡油菌(Cantharellus cibarius)浸液、煎剂及水醇提取物的生物活性分析。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022046751

Sandipta Ghosh, Gouri Basak, Rituparna Saha, Krishnendu Acharya

{"title":"Bioactivity Profiling of Infusion, Decoction, and Hydroalcoholic Fraction Obtained from Wild Golden Chanterelle Mushroom, Cantharellus cibarius (Agaricomycetes).","authors":"Sandipta Ghosh, Gouri Basak, Rituparna Saha, Krishnendu Acharya","doi":"10.1615/IntJMedMushrooms.2022046751","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022046751","url":null,"abstract":"Cantharellus cibarius Fr. is one of the most desirable, popularly known wild edible mushrooms of the genus Cantharellus. Besides having nutritional benefits, this mushroom is reported to harbor significant medicinal potential. In present study, we describe for the first-time bioactive metabolites content and medicinal activities of three different types of extracts including infusion, decoction, and hydroalcoholic fraction from wild Cantharellus cibarius of West Bengal. Bioactive metabolites quantification revealed the phenol and flavonoids present in the range between 0.56-1.46 mg of GAE/g of dried fruit bodies and 0.12-0.29 mg of QE/g of dried fruit bodies, respectively, whereas ascorbic acid contents were also found. Antioxidant activity was assessed using six in vitro systems; decoction displayed better results in all investigated assays with EC50 values ranging between 0.05 and 0.34 mg/ml whereas hydroalcoholic extract showed highest total antioxidant capacity (18 ± 1.61 μg AAE per mg of extract) than other extracts. Moreover, infusion and decoction were found to scavenge highly reactive free radicals like hydroxyl and nitric oxide with their EC50 values ranging between 0.26 and 0.91 mg/ml. Additionally, anti-inflammatory potential of the extracts was evaluated using protein denaturation assay. Hydroalcoholic extract at a concentration range of 0.005-0.1 mg/ml showed comparatively better activity than decoction and infusion, although all the extracts presented dose dependent inhibition of heat induced protein denaturation. Altogether, the present investigation is expected to extend the existing knowledge of this species and recommended its use in pharmaceutical industries as an effective mycomedicine.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 2","pages":"23-33"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10680365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Maitake Medicinal Mushroom, Grifola frondosa (Agaricomycetes), and Its Neurotrophic Properties: A Mini-Review. 灰树花药菇，灰树花菌类及其神经营养特性综述。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022046849

Adrina Mohamad Naguib, Yasaaswini Apparoo, Chuan Xiong, Chia Wei Phan

{"title":"Maitake Medicinal Mushroom, Grifola frondosa (Agaricomycetes), and Its Neurotrophic Properties: A Mini-Review.","authors":"Adrina Mohamad Naguib, Yasaaswini Apparoo, Chuan Xiong, Chia Wei Phan","doi":"10.1615/IntJMedMushrooms.2022046849","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022046849","url":null,"abstract":"Neurodegeneration is one of the most common manifestations in an aging population. The occurrence of oxidative stress and neuroinflammation are the main contributors to the phenomenon. Neurologic conditions such as Alzheimer's disease (AD) and Parkinson's disease (PD) are challenging to treat due to their irreversible manner as well as the lack of effective treatment. Grifola frondosa (Dicks.: Fr.) S.F. Gray, or maitake mushroom, is believed to be a potential choice as a therapeutic agent for neurodegenerative diseases. G. frondosa is known to be a functional food that has a wide variety of medicinal purposes. Thus, this review emphasizes the neuroprotective effects and the chemical composition of G. frondosa. Various studies have described that G. frondosa can protect and proliferate neuronal cells through neurogenesis, antioxidative, anti-inflammatory, and anti-β-amyloid activities. The mechanism of action behind these therapeutic findings in various in vitro and in vivo models has also been intensively studied. In this mini review, we also summarized the chemical composition of G. frondosa to provide a better understanding of the presence of nutritional compounds in G. frondosa.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 2","pages":"11-22"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10680750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant Potential and Stability of Oxidative Sunflower Oil by Using the Ethanolic Extracts of Saprophytic Edible Cultivable Mushrooms from Pakistan. 利用巴基斯坦腐生可食用菌乙醇提取物研究葵花籽油的抗氧化潜力及稳定性。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023048539

Aneeqa Ghafoor, Abdul Rehman Niazi

引用次数: 0

Determination on Tree Species Selection for Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Cultivation by Fourier Transform Infrared and Two-Dimensional Infrared Correlation Spectroscopy. 傅里叶变换红外与二维红外相关光谱法测定灵芝、灵芝菌丝菌栽培树种选择

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022046594

Guansheng Qiu, Jin Lan, Weiwei Zhang, Liankui Wen, Choong Yew Keong, Xiangdong Chen

{"title":"Determination on Tree Species Selection for Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Cultivation by Fourier Transform Infrared and Two-Dimensional Infrared Correlation Spectroscopy.","authors":"Guansheng Qiu, Jin Lan, Weiwei Zhang, Liankui Wen, Choong Yew Keong, Xiangdong Chen","doi":"10.1615/IntJMedMushrooms.2022046594","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022046594","url":null,"abstract":"As a wood-degrading Agaricomycetes mushroom, Ganoderma lucidum can be cultivated on broad-leaf hardwoods. Generally, producers care about the yield, but not the quality of G. lucidum cultivated by different tree species. In this study, five broad-leaf hardwood tree species-Quercus variabilis Bl. (Qv), Castanea mollissima Bl. (Cm), Liquidambar formosana Hance (Lf), Dalbergia hupeana Hance (Dh), and Platycarya strobilacea Sieb. et Zucc. (Ps)-were selected for cultivating of G. lucidum. The chemical compositions of G. lucidum fruiting bodies produced by these tree species were determined by Fourier transform infrared and two-dimensional infrared correlation spectroscopy in order to select the most suitable tree species for cultivation. The overall spectra showed less discrimination of each peak variation detected and properly kept most of the primary metabolites. The second derivative unfolded the stagnation of the first spectrum and more base peaks were detected especially in the range of the first two sections. The protein content contained in G. lucidum cultivated on Ps was 92%, like that on Dh. On the other hand, only 27% similarity was determined in G. lucidum cultivated on Ps and Qv. Therefore, the correlation of this range for the protein content can help in tree species selection. The active sequence of 2DIR spectral could be determined by the active bonding of the component reacted to the perturbation. The result could provide a scientific basis for the selection of tree species and the comprehensive utilization of broad-leaf tree resources on G. lucidum cultivation.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 1","pages":"65-76"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9228677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polysaccharide Elicitors Affect the Yield, Polysaccharide Synthase and Antibacterial Activity of Intracellular Polysaccharides from Submerged Culture of Cordyceps milifaris (Ascomycetes). 多糖激发子对虫草子囊菌胞内多糖产量、多糖合酶及抑菌活性的影响。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2022046732

Kai Ding, Yongxia Wang, Chunchao Han

{"title":"Polysaccharide Elicitors Affect the Yield, Polysaccharide Synthase and Antibacterial Activity of Intracellular Polysaccharides from Submerged Culture of Cordyceps milifaris (Ascomycetes).","authors":"Kai Ding, Yongxia Wang, Chunchao Han","doi":"10.1615/IntJMedMushrooms.2022046732","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2022046732","url":null,"abstract":"This study aimed to increase the yield of Cordyceps militaris intracellular polysaccharide (IPS) by adding elicitors. By comparing the effects of different elicitors on the IPS yield, three polysaccharide elicitors with significant promoting effect were screened out: Tween 80, pH, and vitamin B6 (VB6). We combined these elicitors and optimized the composition of the complex elicitor using response surface methodology to further improve the yield of IPS. The highest percentage of increased yield was 82.52 ± 0.48% obtained at a Tween concentration of 0.41% (w/v), pH of 4.98, and VB6 concentration of 0.17 mg/mL. Simultaneously, the mechanism of promoting high yield of IPS was preliminarily discussed. The complex elicitor may promote the synthesis of IPS by influencing the activity of polysaccharide synthase. Furthermore, the antibacterial activity against Staphylococcus aureus and Escherichia coli was evaluated. The addition of the complex elicitor increased the antibacterial activity of IPS. Therefore, our findings will lead the way for large scale industrial fermentations and commercial uses of IPS from C. militaris as antibacterial constituents.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 2","pages":"35-48"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10680749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Activity of Culinary-Medicinal Polypore Mushroom Lentinus tigrinus (Agaricomycetes). 烹饪药用多孔蘑菇的抗菌活性。

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023048172

Yasaman Yazdi, Mohammad Reza Rezaei, Hamid R Pourianfar

{"title":"Antibacterial Activity of Culinary-Medicinal Polypore Mushroom Lentinus tigrinus (Agaricomycetes).","authors":"Yasaman Yazdi, Mohammad Reza Rezaei, Hamid R Pourianfar","doi":"10.1615/IntJMedMushrooms.2023048172","DOIUrl":"10.1615/IntJMedMushrooms.2023048172","url":null,"abstract":"Medicinal mushrooms belonging to Lentinus spp. exhibit significant antibacterial activities, but little attention has been paid to their efficacy against the food-borne pathogen, Bacillus cereus. The present study for the first time quantitatively evaluated the antibacterial activity of different extracts from fruiting bodies of a well-authenticated Iranian native strain of medicinal mushroom, Lentinus tigrinus, against Gram-positive spore-forming bacterium B. cereus. The findings revealed that the acetone extract inhibited the growth of B. cereus at concentrations as low as 31.25 μg/ML, while it had no effect against Escherichia coli and Staphylococcus aureus even at 10,000 μg/ML. The rest of the bacteria were also susceptible to the acetone extract at concentrations greater than 5 mg/ML. Antibacterial activities of the methanol-ethyl acetate extract and the hot water extract were significantly weaker than that of the acetone extract, which contained high amounts of total phenols (5.83 ± 0.08 mg GAE/g, dw), while Fourier transform infrared spectroscopy (FT-IR) confirmed the presence of functional groups, such as hydroxyl, carbonyl, amide, and amine. Further studies by scanning electron microscopy (SEM) confirmed obvious changes in the morphology of B. cereus in response to the acetone extract of L. tigrinus. This study may suggest that L. tigrinus could be a good natural source for isolating and purifying antibacterial compounds against B. cereus.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 6","pages":"21-30"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9900585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review. 蘑菇多糖的免疫和抗肿瘤活性研究进展

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023049062

Yating Dong, Tao Wang, Jin Zhao, Bingcheng Gan, Rencai Feng, Renyun Miao

{"title":"Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review.","authors":"Yating Dong, Tao Wang, Jin Zhao, Bingcheng Gan, Rencai Feng, Renyun Miao","doi":"10.1615/IntJMedMushrooms.2023049062","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2023049062","url":null,"abstract":"Mushrooms are full of nutrition and have beneficial properties for human health. Polysaccharides are the main component of edible and medicinal mushrooms, especially β-glucans, which have attracted much more attention for their complex structure and diverse biological activities. Among all the diverse medicinal activities of mushroom polysaccharides, antitumor and immune-enhancing activities are two excellent bioactivities that have much more potential and deserve application. Their bioactivities are highly dependent on their structural features, including molecular weight, monosaccharide composition, degree of branching, type and configuration of glycosidic bonds, substituent pattern, and chain conformation. This review summarizes the current method for obtaining polysaccharides from mushrooms, chemical characterizations of the structures and their roles in immune and antitumor activities. In addition, the methods for preparation of the polysaccharide derivatives and the potential medicinal clinical application are also discussed in this review, which may provide new guidance for mushroom polysaccharide development.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 8","pages":"1-17"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9964679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Exogenous Lanthanum Nitrate on the Active Substance Content and Antioxidant Activity of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes). 外源硝酸镧对冬虫夏草活性物质含量及抗氧化活性的影响

IF 1.2 4区生物学

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023048203

Qi Gao, Debin Zhang, Wenjing Ding, Wenjiao Zhai, Chunmei Gu, Shaofen Guo

{"title":"Effects of Exogenous Lanthanum Nitrate on the Active Substance Content and Antioxidant Activity of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).","authors":"Qi Gao, Debin Zhang, Wenjing Ding, Wenjiao Zhai, Chunmei Gu, Shaofen Guo","doi":"10.1615/IntJMedMushrooms.2023048203","DOIUrl":"https://doi.org/10.1615/IntJMedMushrooms.2023048203","url":null,"abstract":"Cordyceps militaris is a medicinal and edible mushroom. Researchers often add exogenous substances to the culture medium to increase the active substance content in C. militaris. However, the effect of earth elements on the active substance content in C. militaris and its antioxidant effects have not been reported. In this study, the active substance content in C. militaris treated with lanthanum nitrate was determined using high-performance liquid chromatography and ultraviolet spectrophotometry, and the effect on the antioxidant capacity of C. militaris after lanthanum nitrate spraying was further explored. The results showed that, in the experimental concentration range, the two concentrations of 10 mg/L and 50 mg/L had a significant influence on the active substance content of C. militaris. When the concentration of lanthanum nitrate was 10 mg/L, the synthesis of pentostatin and cordycepin was promoted. When the concentration of lanthanum nitrate was 50 mg/L, it significantly promoted the synthesis of cordycepin, and the ferric-reducing power and DPPH· scavenging rate of C. militaris treated at this concentration were significantly higher than those of the control group. However, lanthanum nitrate had no significant effect on ergosterol synthesis (P > 0.05). Finally, considering that the residual amount of lanthanum in C. militaris and the residual amount of lanthanum in 50 mg/L lanthanum nitrate-treated C. militaris is within the allowable daily intake of 4.2 mg for humans, the optimal concentration of lanthanum nitrate-treated C. militaris is 50 mg/L.","PeriodicalId":14025,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 6","pages":"41-54"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9901987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0