{"title":"The 1919-21 influenza pandemic in Greenland.","authors":"Mathias Mølbak Ingholt, Lone Simonsen, Svenn-Erik Mamelund, Paneeraq Noahsen, Maarten van Wijhe","doi":"10.1080/22423982.2024.2325711","DOIUrl":"10.1080/22423982.2024.2325711","url":null,"abstract":"<p><p>In Alaska, the 1918-20 influenza pandemic was devastating, with mortality rates up to 90% of the population, while in other arctic regions in northern Sweden and Norway mortality was considerably lower. We investigated the timing and age-patterns in excess mortality in Greenland during the period 1918-21 and compare these to other epidemics and the 1889-92 pandemic. We accessed the Greenlandic National Archives and transcribed all deaths from 1880 to 1921 by age, geography, and cause of death. We estimated monthly excess mortality and studied the spatial-temporal patterns of the pandemics and compared them to other mortality crises in the 40-year period. The 1918-21 influenza pandemic arrived in Greenland in the summer of 1919, one year delayed due to ship traffic interruptions during the winter months. We found that 5.2% of the Greenland population died of the pandemic with substantial variability between counties (range, 0.1% to 11%). We did not see the typical pandemic age-pattern of high young-adult mortality, possibly due to high baseline mortality in this age-group or remoteness. However, despite substantial mortality, the mortality impact was not standing out relative to other mortality crises, or of similar devastation reported in Alaskan populations.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2325711"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maja Hykkelbjerg Nielsen, Annesofie Lunde Jensen, Michael Lynge Pedersen, Lene Seibæk
{"title":"Living with chronic obstructive pulmonary disease or type 2 diabetes in Greenland - a qualitative interpretive description study.","authors":"Maja Hykkelbjerg Nielsen, Annesofie Lunde Jensen, Michael Lynge Pedersen, Lene Seibæk","doi":"10.1080/22423982.2023.2296706","DOIUrl":"10.1080/22423982.2023.2296706","url":null,"abstract":"<p><p>Non-communicable diseases such as chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2D) represent major challenges for health systems all over the world. In an interview study, we explored patient experiences and perspectives of being diagnosed and living with COPD or T2D in Greenland. Participants (<i>n</i> = 24) were selected by purposeful sampling and recruited by phone. We conducted individual semi-structured interviews at the National Hospital in Nuuk and the four regional hospitals. Interviews were audio-recorded, transcribed verbatim, and analysed using interpretive description. Three themes emerged: shock and shame on receiving the diagnosis, coping with a changed life, and varying needs for care and communication. We found that being diagnosed with COPD or T2D required a rapid change in the participants' everyday lives and lifestyle behaviours. Some self-managed their disease well and were able to transfer their knowledge and integrate it into their daily lives, while others struggled to make lifestyle changes. Additionally, living with COPD or T2D could be related to silence and shame. The findings contribute to a better understanding of living with COPD or T2D in the Arctic region and the development of future, culturally-adapted patient education initiatives.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2296706"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10763871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix N R Wood, Rosemary Hartley, Rebecca Boys, Timothy Parham, Jonathon Lowe, Matthew Warner
{"title":"Repeated freezing to very low temperatures does not impact the amount ejected from EpiPen® and Jext® adrenaline autoinjectors.","authors":"Felix N R Wood, Rosemary Hartley, Rebecca Boys, Timothy Parham, Jonathon Lowe, Matthew Warner","doi":"10.1080/22423982.2024.2367273","DOIUrl":"10.1080/22423982.2024.2367273","url":null,"abstract":"<p><p>It has previously been shown that EpiPen® autoinjectors are likely to activate normally following up to five excursions to -25°C but data about the post-freezing performance of other brands of adrenaline autoinjectors has not previously been published. Additionally, conditions experienced by polar medics may be substantially colder than this and the performance of adrenaline autoinjectors following more extreme freeze-thaw cycles remains uncharacterised. Investigators in Antarctica and the United Kingdom performed laboratory testing on two brands of adrenaline autoinjector, EpiPen® and Jext® (12 devices of each type). A single freeze-thaw cycle involved freezing the device to -80°C then allowing it to come to room temperature. Devices were exposed to 0, 1, 5 or 15 freeze-thaw cycles. The mass of liquid ejected from each device, when activated, was then measured. No significant differences in the mass of the liquid ejected was found between the test groups. Multiple freeze-thaw cycles to -80°C are unlikely to significantly impact the amount of adrenaline solution expelled from EpiPen® and EpiPen® autoinjectors. This preliminary finding encourages further work investigating the safety and effectiveness of adrenaline autoinjectors after exposure to very low temperatures. This information would be valuable for future polar medics planning and delivering medical provision in extreme environments.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2367273"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141320897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morgen Bertheussen, Mylene Riva, Brittany Wenniserí Iostha Jock, Christopher Fletcher, Pierre Ayotte, Gina Muckle, Natalia Poliakova, Richard Bélanger
{"title":"Using latent class analysis to operationalize a wholistic assessment of Inuit health and well-being.","authors":"Morgen Bertheussen, Mylene Riva, Brittany Wenniserí Iostha Jock, Christopher Fletcher, Pierre Ayotte, Gina Muckle, Natalia Poliakova, Richard Bélanger","doi":"10.1080/22423982.2024.2322186","DOIUrl":"10.1080/22423982.2024.2322186","url":null,"abstract":"<p><p>Many indigenous cultures conceptualize health wholistically, whereby physical, mental, spiritual and relational dimensions of health are interconnected. Yet, quantitative approaches to studying Indigenous health remain anchored in western perspectives, that separate the dimensions of health. This paper aims to operationalize a wholistic indicator of health based on the IQI model of Inuit health. Variables from the 2017 Nunavik Health Survey (<i>N</i> = 1196) were selected based on their representativeness of IQI model. Exploratory Latent Class Analysis (LCA) was used to identify wholistic health profiles. Once participants assigned to their health profile, sociodemographic characteristics were compared across profiles, and multinomial regression models were used to examine the relationship between community-level social determinants of health and the profiles. The LCA revealed three health profiles, labelled as \"<i>excellent\"</i>, \"<i>good\"</i> and \"<i>fair\"</i> based on the distribution of answers to the indicators. Nunavimmiut in \"<i>excellent\"</i> and \"<i>good\"</i> health were more likely to: rate their health positively; be over 30 years old; be in a relationship; and have participated or volunteered in community events. Nunavimmiut in \"<i>fair</i>\" health tended to report lower levels of community cohesion, family relationships, and emotional support. Intergrating culturally relevant models of health can support improved health status assessments and identify opportunities for health promotion.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2322186"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10930148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Trine Jul Larsen, Maria Bråthen Pettersen, Helena Nygaard Jensen, Michael Lynge Pedersen, Henrik Lund-Andersen, Marit Eika Jørgensen, Stine Byberg
{"title":"The use of artificial intelligence to assess diabetic eye disease among the Greenlandic population.","authors":"Trine Jul Larsen, Maria Bråthen Pettersen, Helena Nygaard Jensen, Michael Lynge Pedersen, Henrik Lund-Andersen, Marit Eika Jørgensen, Stine Byberg","doi":"10.1080/22423982.2024.2314802","DOIUrl":"10.1080/22423982.2024.2314802","url":null,"abstract":"<p><p><b>Background:</b> Retina fundus images conducted in Greenland are telemedically assessed for diabetic retinopathy by ophthalmological nurses in Denmark. Applying an AI grading solution, in a Greenlandic setting, could potentially improve the efficiency and cost-effectiveness of DR screening.<b>Method:</b> We developed an AI model using retina fundus photos, performed on persons registered with diabetes in Greenland and Denmark, using Optos® ultra wide-field scanning laser ophthalmoscope, graded according to ICDR.Using the ResNet50 network we compared the model's ability to distinguish between different images of ICDR severity levels in a confusion matrix.<b>Results:</b> Comparing images with ICDR level 0 to images of ICDR level 4 resulted in an accuracy of 0.9655, AUC of 0.9905, sensitivity and specificity of 96.6%.Comparing ICDR levels 0,1,2 with ICDR levels 3,4, we achieved a performance with an accuracy of 0.8077, an AUC of 0.8728, a sensitivity of 84.6% and a specificity of 78.8%. For the other comparisons, we achieved a modest performance.<b>Conclusion:</b> We developed an AI model using Greenlandic data, to automatically detect DR on Optos retina fundus images. The sensitivity and specificity were too low for our model to be applied directly in a clinical setting, thus optimising the model should be prioritised.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2314802"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10877649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139740957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joo Roerholm Svendsen, Michael Lynge Pedersen, John Hauerberg, Ole Gredal
{"title":"Subarachnoid haemorrhage and intracranial aneurysms in Greenland in the period 2018-2021: incidence, outcome and familial disposition.","authors":"Joo Roerholm Svendsen, Michael Lynge Pedersen, John Hauerberg, Ole Gredal","doi":"10.1080/22423982.2024.2356889","DOIUrl":"10.1080/22423982.2024.2356889","url":null,"abstract":"<p><p>Subarachnoid haemorrhages (SAH) caused by rupture of intracranial aneurysms (IA) are a severe condition. Earlier studies found a higher incidence of SAH in Greenlandic patients compared to Danish patients, with familial aggregation also higher in Greenland. However, updated data is lacking. To investigate the contemporary incidence, outcome, and familial disposition of SAH/IA in Greenlandic patients in 2018-2021. Greenlandic patients diagnosed with ruptured or unruptured IA (UIA) during 2018-2021 were included. Data was obtained from patient files, x-ray department, and discharge registry. Incidence rates were estimated as cases/100,000/year. Direct age-standardised incidence rates were calculated using WHO 2000-2025 as standards. Of 30 SAH patients, 20 (66.7%) were females, 10 (33.3%) males. Of 36 UIA patients, 27 (75.0%) were females, 9 (25.0%) males. For SAH, crude incidence was 13.4/100,000/year, age-standardised incidence was 10.8/100,000/year. Familial history was observed in 30.0% of SAH patients. 5 patients (16.7%) died before treatment, 28-day case-fatality rate (CFR) for all patients was 23.3%. Overall and age-standardised incidence rates were similar to previous studies but higher among females and compared to neighbouring countries. A high occurrence of familial history was reported. SAH remains a serious condition in Greenland, as evidenced by five fatalities before treatment was administered.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2356889"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11134107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141093282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grateful to be working together to advance Arctic health and well-being.","authors":"Rhonda M Johnson","doi":"10.1080/22423982.2024.2435224","DOIUrl":"10.1080/22423982.2024.2435224","url":null,"abstract":"","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2435224"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11610347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khaled Abass, Alexey A Dudarev, Bryan Adlard, Zoe Gillespie, Arja Rautio, Luke Nych, Cheryl Khoury
{"title":"Methodologies and challenges in Arctic human health risk assessment: case studies and evaluation of current practices.","authors":"Khaled Abass, Alexey A Dudarev, Bryan Adlard, Zoe Gillespie, Arja Rautio, Luke Nych, Cheryl Khoury","doi":"10.1080/22423982.2024.2428471","DOIUrl":"10.1080/22423982.2024.2428471","url":null,"abstract":"<p><p>In Arctic populations, a primary route of exposure to contaminants is through the diet. The health risks associated with these exposures can be characterised by conducting human health risk assessments. However, while there is guidance from many international and national organisations, there are limited examples of human health risk assessment in the Arctic. The 2022 AMAP Human Health Assessment Report was the first AMAP report to describe, in one place, the utility of food-based, dietary intake-based and human tissue-based contaminant data in estimating risk. Here, we present available tools, case studies and challenges associated with conducting human health risk assessments in the Arctic. Future efforts in the Arctic should be able to use this information to best interpret human exposure to contaminants in a risk-based context.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2428471"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix N R Wood, Jason Hicks, Rhiannon Wilkinson, Rosemary Hartley, Jonathon Lowe
{"title":"Orientation affects the integrity of glass ampoules of 1 in 1000 adrenaline on exposure to very low temperatures.","authors":"Felix N R Wood, Jason Hicks, Rhiannon Wilkinson, Rosemary Hartley, Jonathon Lowe","doi":"10.1080/22423982.2024.2309756","DOIUrl":"10.1080/22423982.2024.2309756","url":null,"abstract":"<p><p>In very cold environments, it may be burdensome or impossible for the polar medic to prevent medicines from freezing. We sought to investigate whether orientation affected the risk that glass ampoules of 1 in 1000 adrenaline, an important emergency drug, would break during freezing and subsequent thawing. Ampoules of adrenaline were orientated either upright, horizontally or inverted. They were exposed to freezing temperatures (-25°C or -80°C) and then allowed to thaw. A crossover design was used whereby the orientation of unbroken ampoules was changed for the next trial. No ampoules broke when frozen at -25°C and then thawed. When this was repeated at -80°C, ampoules reliably broke unless they were upright with no liquid in the top part of the ampoule. Upright orientation prevents the breakage of glass ampoules of 1 in 1000 adrenaline rapidly frozen at -80°C. The polar medic may consider storing ampoules upright if they are to be exposed to very low temperatures.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2309756"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Key recommendations and research priorities of the 2021 AMAP human health assessment.","authors":"Cheryl Khoury, Pál Weihe","doi":"10.1080/22423982.2024.2408057","DOIUrl":"10.1080/22423982.2024.2408057","url":null,"abstract":"<p><p>Over the last three decades, the Arctic Monitoring and Assessment Programme has published five human health assessments. These assessments have summarised the current state of the science regarding environmental contaminants and human health in the Arctic. The 2021 Human Health Assessment Report had a particular focus on dietary transitions, in addition to human biomonitoring levels and trends, health effects, risk assessment methodologies, risk communication and multi-disciplinary approaches to contaminants research. The recommendations and research priorities identified in the latest assessment are summarised here to assist decision- and policy-makers in understanding and addressing the impacts of contaminants on human populations in the Arctic.</p>","PeriodicalId":13930,"journal":{"name":"International Journal of Circumpolar Health","volume":"83 1","pages":"2408057"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11451291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}