International Journal of Current Pharmaceutical Research最新文献

STUDY OF PREVALENCE OF POLYCYSTIC OVARIAN SYNDROME AMONG ADOLESCENT AND YOUNG ADULT STUDENTS OF NAVODAYA GROUP OF INSTITUTIONS 纳沃达亚教育机构青少年学生多囊卵巢综合征患病率研究

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5003

Kolan Pallavi, H. K.

引用次数: 0

PEUTZ-JEGHERS POLYP AS A LEAD POINT FOR ILEOCOLIC INTUSSUSCEPTION IN A YOUNG FEMALE: A CASE REPORT 佩兹-杰格息肉是一名年轻女性回结肠肠套叠的导引点：病例报告

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4099

Smruti Ranjan Hota, Pragnya Paramita Mishra, Debashis Nanda

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OCULAR CYSTICERCOSIS: A CASE REPORT 眼囊尾蚴病：病例报告

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5018

Aditya Kashyap, Shaloo Negi, Smriti Sharma

引用次数: 0

A COMPARATIVE STUDY OF TRANSDERMAL BUPRENORPHINE PATCH VERSUS TRANSDERMAL DICLOFENAC PATCH FOR POST-OPERATIVE ANALGESIA IN ELECTIVE BELOW UMBILICAL SURGERIES 透皮丁丙诺啡贴片与透皮双氯芬酸贴片用于脐下择期手术术后镇痛的比较研究

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4095

Farha Deeba Rajasab, Sherley S. Cherian, Rakesh Kalappa, Haripriya Ramachandran

{"title":"A COMPARATIVE STUDY OF TRANSDERMAL BUPRENORPHINE PATCH VERSUS TRANSDERMAL DICLOFENAC PATCH FOR POST-OPERATIVE ANALGESIA IN ELECTIVE BELOW UMBILICAL SURGERIES","authors":"Farha Deeba Rajasab, Sherley S. Cherian, Rakesh Kalappa, Haripriya Ramachandran","doi":"10.22159/ijcpr.2024v16i4.4095","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4095","url":null,"abstract":"Objective: Effective postoperative pain management is crucial for recovery and patient satisfaction. This study compares the efficacy and safety of transdermal buprenorphine, an opioid analgesic, with diclofenac, a non-steroidal anti-inflammatory drug (NSAID), for postoperative pain relief in elective below umbilical surgeries.\u0000Methods: Hundred patients undergoing elective below-umbilical surgeries were randomized into two groups to receive either a transdermal buprenorphine patch or a diclofenac patch. Pain scores using the Numeric Rating Scale (NRS), functional recovery assessed by the WOMAC Index, and patient satisfaction were measured at baseline, 1 w, 2 w, and 4 w post-application.\u0000Results: Both groups showed significant pain reduction over time. However, at 1 and 2 W post-application, the diclofenac group exhibited greater pain relief (p<0.001) and higher patient satisfaction. By the 4 w, differences in pain scores and WOMAC Index between the groups were not statistically significant, indicating similar long-term efficacy.\u0000Conclusion: While both transdermal buprenorphine and diclofenac patches are effective for postoperative pain management, diclofenac patches offer superior short-term relief and patient satisfaction. Tailoring pain management strategies to individual patient needs and recovery phases is essential for optimizing postoperative care.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TUBERCULOSIS AND ITS ASSOCIATION WITH CD4+T CELL COUNT AND VIRAL LOAD AMONG HIV POSITIVE PATIENTS IN A TERTIARY CARE HOSPITAL 一家三级医院的艾滋病毒阳性患者中的结核病及其与 cd4+t 细胞计数和病毒载量的关系

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5042

Nigel Jose, Aruna Bula, P. R. Kumari, P. Kamala

{"title":"TUBERCULOSIS AND ITS ASSOCIATION WITH CD4+T CELL COUNT AND VIRAL LOAD AMONG HIV POSITIVE PATIENTS IN A TERTIARY CARE HOSPITAL","authors":"Nigel Jose, Aruna Bula, P. R. Kumari, P. Kamala","doi":"10.22159/ijcpr.2024v16i4.5042","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5042","url":null,"abstract":"Methods: The present study was a prospective study conducted from April 2022 to March 2023 in 4551 patients. Samples of 238 patients newly diagnosed with HIV attending Integrated Counselling and Testing Centre (ICTC), Visakhapatnam, Andhra Pradesh, India and registered for Antiretroviral Therapy (ART) were taken. 5 ml of blood sample was collected aseptically and tested for HIV. The 238 HIV-positive samples were tested for CD4 counts at presentation and after 6 mo using flow cytometry (Sysmex Partec CyFlow Flow cytometer). They were further subjected to real-time RT-PCR to detect viral load at 6 mo follow-up.\u0000Results: Out of 238 HIV-positive cases, predominant gender being males with 140 (58.82%) and the predominant age group was 31-40 y. At 6 mo follow-up, 19 patients (8%) were diagnosed as having TB. The mean CD4 counts at baseline and after 6 mo of antiretroviral therapy (ART)) was 296±229 and 436±271 cells/mm3 (p value of<0.001) for entire study group. The mean baseline CD4 count in patients who were not diagnosed with TB at the time of follow-up and those who were diagnosed as having developed TB was 307±232 cells/mm3 and 167±135 cells/mm3 respectively. At six mo follow-up, 32(14.6%) HIV patients who did not develop TB and 8(42.1%) patients who developed TB still had their CD4 counts<200 cells/mm3. This was statistically significant with a p value=0.019. Significant difference was not found between the two subgroups as the HIV-only group had 192(87.7%) patients and 16(84.2%) patients from newly diagnosed TB patients had their viral loads below detection levels.\u0000Conclusion: low CD4 counts at the baseline was a high-risk factor for the development of tuberculosis in HIV patients. The viral load values at 6-month follow-up did not prove to be significantly linked to the development of tuberculosis.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TRADITIONALLY USED MEDICINAL PLANTS FOR WOUND HEALING IN THIRUVALLUR DISTRICT, TAMIL NADU, INDIA 印度泰米尔纳德邦 Thiruvallur 地区用于伤口愈合的传统药用植物

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4086

K. I. D., U. S., E. K., Kavitha Manivannan, Malathi Ramasamy

{"title":"TRADITIONALLY USED MEDICINAL PLANTS FOR WOUND HEALING IN THIRUVALLUR DISTRICT, TAMIL NADU, INDIA","authors":"K. I. D., U. S., E. K., Kavitha Manivannan, Malathi Ramasamy","doi":"10.22159/ijcpr.2024v16i4.4086","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4086","url":null,"abstract":"The present study aims to enumerate the ethno-medicinal uses of plants by the Irular communities residing around the Thiruvallur district. The medicinal use of (49) plants belonging to 39 families was identified and recorded by the tribes, along with their botanical identities and methods of drug preparation. The drugs administered locally to heal wounds, including antibiotics, antiseptics, etc., and the necessary information related to the traditional medicinal plants were highlighted in this paper. Wound healing activity is a cellular and biochemical process for restoring the original structure and functions of damaged tissue. The wound may occur from a physical, chemical, thermal, microbial, or immunological insult to the tissues. Various parts of the plants have been in use for several years in tribal communities, traditionally for treating many diseases like skin, colic, sores, cancer, etc. Due to their minimal side effects. The natural agents present in the plants induce wound healing and regeneration from tissue loss by multiple mechanisms. Plant extracts have immense potential for the treatment of wound healing activity. In this review, we focused on the wound healing activity with the pharmacological process of medicinal plants.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASSESSMENT OF EYE DROP INSTALLATION TECHNIQUE AMONG PATIENTS ATTENDING OUTPATIENT CLINIC AT PT. JLNGMC, CHAMBA 对上杭县人民医院门诊患者滴眼药水技术的评估樟木头联合国民医疗中心

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5004

Shaloo Negi, Aditya Kashyap, Smriti Sharma

{"title":"ASSESSMENT OF EYE DROP INSTALLATION TECHNIQUE AMONG PATIENTS ATTENDING OUTPATIENT CLINIC AT PT. JLNGMC, CHAMBA","authors":"Shaloo Negi, Aditya Kashyap, Smriti Sharma","doi":"10.22159/ijcpr.2024v16i4.5004","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5004","url":null,"abstract":"Objective: A good eye drops installation technique and its knowledge is vital for curing eye ailments and preventing eye from harmful effects of over-dose and under-dose of drugs. The current study assessed the eye drop installation technique and corrected it by imparting them education regarding the same.\u0000Methods: A total of 120 patients were enrolled in the cross-sectional study using consecutive sampling technique till the sample size was achieved in a tertiary care hospital. The participants were observed by the trained observers for their steps of technique for installing eye drops and the errors were noted which were corrected by the observers and followed up till 3 visits to observe a change in the steps of technique.\u0000Results: The mean age of study participants was 41.44±15.4 y. Majority of them were in the age group 18-30 y (35%), females (55.8%), and belonging to upper middle socio-economic status (31.7%). Majority of study participants had 6/6 VA in right eye (65%) and left eye (61.7%). “Drop land on first attempt” and “direct bottle towards eyes” showed maximum improvement of 45.8% each followed by “tilt head while putting” showed 45 % improvement between 1st visit and 3rd visit. “Trouble putting drops” showed least improvement by 20% between 1st and 3rd visit. All the favorable ophthalmic practices showed a statically significant (<0.05) increase in their proportion in each visit.\u0000Conclusion: A high prevalence of errors while installing eye drops among participants were observed which were improved by educating them about right steps, as observe in follow up visits.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GIANT CELL TUMOUR OF TENDON SHEATH IN THE FOOT: A RARE CASE REPORT 足部腱鞘巨细胞瘤：罕见病例报告

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4093

Girish Garg, Raghuveer Meena, Sandeep Kumar, Mahaveer Meena

引用次数: 0

PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF ATLANTIA MONOPHYLLA (AM) EXTRACT 单叶芸香树（AM）提取物的植物化学分析和抗菌活性

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4078

M. Haritha, BL Kudagi, Pathapati Mohan, V. Chandra, SK. Salma Kamal, R. Manchi, A. Nelavala

{"title":"PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF ATLANTIA MONOPHYLLA (AM) EXTRACT","authors":"M. Haritha, BL Kudagi, Pathapati Mohan, V. Chandra, SK. Salma Kamal, R. Manchi, A. Nelavala","doi":"10.22159/ijcpr.2024v16i4.4078","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4078","url":null,"abstract":"Objective: Plants have long been recognised for their wide range of biological properties, including antibacterial, analgesic, anticancer, antipyretic, and antihypertensive action. They are also a significant source of several chemicals with biological activity. The Rutaceae family consists of a small shrub Atlantia monophylla. It is available all over India. The leaves were employed as an insect repellent and to alleviate swellings. The root bark has been found to contain atalaphyllinine, atalantin, dehydroatalantin, cycloepiatalantin, and atalaphylline 3, 5-dimethyl ether. Essential oil extracted from the leaves was reported to have antimicrobial properties.\u0000Methods: To evaluate the phytochemicals Standard chemical methods for each o the compounds were used – like Tannins (0.1% ferric chloride), saponins (2 ml of water)/flavonoids (with NaOH), Alkaloids (Drangandooff reagent), protein (Million’s reagent) steroids (10% sulphuric acid), anthraquinones (aqueous ammonia), Phenols (lead acetate), terpenoids, (3% sulphuric acids) Carbohydrates (Benedict’s reagent). Disc plate method was used to evaluate the antimicrobial activity of the extract\u0000Results: The results of this study identified the presence of tannins, flavonoids, alkaloids, proteins, steroids, phenols, terpenoids, and carbohydrates in the AM extract. The microbiological studies revealed better inhibitions of microbes compared to standard drugs.\u0000Conclusion: Tannins, flavonoids, proteins, steroids, phenols, terpenoids, carbohydrates and alkaloids were extracted from the AM extract. The extract has significant microbiological action.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE USE OF SUBCISION IN CONJUNCTION WITH FRACTIONAL CARBON DIOXIDE LASER TO IMPROVE ATROPHIC ACNE SCARS 使用亚切法与点阵二氧化碳激光相结合来改善萎缩性痤疮疤痕

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5019

Priyanka Sharma, Ajit Singh, Aditya Kumar Tripathi

{"title":"THE USE OF SUBCISION IN CONJUNCTION WITH FRACTIONAL CARBON DIOXIDE LASER TO IMPROVE ATROPHIC ACNE SCARS","authors":"Priyanka Sharma, Ajit Singh, Aditya Kumar Tripathi","doi":"10.22159/ijcpr.2024v16i4.5019","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5019","url":null,"abstract":"Objective: Acne is a prevalent skin condition affecting a wide range of age groups, often leading to severe scarring if left untreated. The use of subcision combined with fractional CO2 laser therapy has been posited as a potentially more effective treatment method for atrophic acne scars compared to standalone laser treatment.\u0000Methods: This clinical trial was conducted at Asha Derma Clinic, Gorakhpur, Uttar Pradesh, from 30th March 2023 to 30th March 2024. Thirty patients with ice pick and rolling-type atrophic acne scars were enrolled. Participants were treated on one side of their face with five sessions of fractional CO2 laser and on the other side with one session of subcision with fractional CO2 laser combined with four sessions of fractional CO2 laser alone. Outcomes were assessed through scar improvement and patient satisfaction at 1, 2, and 6 mo post-treatment, with data analysis performed using ANOVA and the Wilcoxon rank-sum test.\u0000Results: Significant improvements were observed in both recovery levels and patient satisfaction. The combined method showed higher recovery percentages (40-65%, Mean±SD: 54.7±7) compared to the laser alone (30-55%, Mean±SD: 43±11.1), with a p-value of 0.0005. Patient satisfaction also favored the combined method (1.8-3, Mean±SD: 6.6±1.2) over laser treatment alone (1.6-4, Mean±SD: 5.2±1.8), with a p-value of 0.0007.\u0000Conclusion: The study demonstrated that subcision combined with fractional CO2 laser therapy significantly enhances recovery levels and patient satisfaction in the treatment of atrophic acne scars, suggesting a robust advantage of integrating both treatments.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0